The clinically organ-confined adenocarcinoma of the

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Book details
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Author :
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Pages : 74 pages
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Publisher : Steinkopff 1994-01-01
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Language : English
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ISBN-10 : 3798509980
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ISBN-13 : 9783798509986
Book Synopsis
Dr. Hans-Peter Schmid has addressed in this monograph the basic dilemmas surrounding prostate
cancer. These dilemmas include the 40 % histologic incidence of invasive cancer in men in
comparison to a 3 % death rate, the extraordinary slow doubling time of four to five years for
untreated early clinical stages (T1 and T2 cancers), the limited life span of even healthy men over
70 years of age, and the national and international debates of how to treat this cancer. It is
important, however, to recognize that despite these uncertainties, prostate cancer is probably the
most predictive of all human solid tumors. Dr. Schmid has addressed the basis for much of this
predictability in this monograph. The level of serum PSA and its rate of increase in the untreated
patient with a prostate size of less than 50 grams is undoubÂ- tedly the most useful of all
measurements in predicting volume and grade of the cancer, but it is closely followed by
assessment of the extent and percent of grade 4 and 5 cancer in six systematic, spatially
separated biopsies. Estimating the amount of suspected cancer on digital rectal examination by
assigning a clinical stage is useful, but far less quantitative than PSA and systematic biopsies. The
Basel series in this monograph adds strong support to these basic concepts. April 1994 ThomasA.
Stamey, M. D. Professor and Chairman Department of Urology Stanford University School of
Medicine Stanford, California, USA v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . V I. 1 Introduction and overview . . . . . . . . . . . . . . . . . . . . . . . . . . .

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