8th Introductory Course Microbiology and Immunology January 13 – 17, 2014 Large Lecture Hall Institute of Plant Biology Zollikerstrasse 107 8008 Zurich Monday 13th 09:00-09:15 Welcome: Annette Oxenius 09:15-10:15 S01 Students’ Session: Immune System Hans Winkler: FoodN’Immunity - Development of an in-vitro test to assess the safety of food-borne nanoparticles Vural Yilmaz: Pattern recognition requirements in vaccination versus immunity to infection Mario Novkovic: Systems immunological analysis of lymph node stromal cell phenotype and function Hung-Wei Cheng: Phenotypic and functional characterization of mesenchymal lymphoid tissue organizer cells S02 S03 S04 Morning Break (10:15-10:30) 10:30-11:15 S05 S06 S07 Students’ Session: Understanding microbal pathogens Katja Becker: Structural & functional analysis of glycosylation on lipoproteins of slow-growing mycobacteria Jon Paulin Zumthor: Reduced to the max? The unusual giardial clathrin coats Rita Costa: Role of epithelial tight junctions and Staphylococcus aureus in chronic Rhinosinusitis Lunch Break (11:15-12:45) 12:45-13:30 S08 S09 S10 Students’ Session: Living Together - Microbial Interactions Angela Suppiger: Analysis of the BDSF quorum sensing circuitry in Burkholderia cenocepacia H111 Elisa Granato: Cooperation and virulence in Pseudomonas aerugionsa Sebastian Dirren: Ménage-a-trois: The amoeba Nuclearia sp. from Lake Zurich with its ecto- & endosymbiotic partners Coffee Break (13:30-14:00) 14:00-14:45 P01 14:45-15:30 P02 Martin Loessner (Intro: Hans Winkler): Molecular microbiology of foodborne pathogens: Using the weapons of the enemy Rolf Kümmerli (Intro: Sebastian Dirren): Microbial cooperation and its role for virulence Coffee Break (15:30-16:00) 16:00-16:45 P03 16:45-17:30 P04 Burkhard Becher (Intro: Corinne De Gregorio): How T-cells talk to myeloid cells Markus Manz (Intro: Maio Novkovic): Hematopoietic stem cells, founders of cellular Immunology Tuesday 14th 09:00-10:00 S11 S12 S13 S14 Students’ Session: The biochemistry of life - Proteins in catalysis & cell biology Jillianne Eyring: Expression and purification of octameric oligosaccharyltransferase from yeast Andrea Ochsner: Understanding methylotrophy Giorgia Brambilla Pisoni: Role of TMX1 in protein folding and in ERassociated-degradation (ERAD) Corinna Lading: To be named Morning Break (10:00-10:30) 10:30-11:15 S15 S16 S17 Students’ Session: Signalling in disease and immune response Urs Mörbe: The role of CXCL13 signalling in lymph node development Gabriele Fenini: Role of MAPKs in NLRP3 inflammasome activation Michel Crameri: The influenza virus protein NS1 interferes with type I interferon-mediated signaling Lunch Break (11:15-12:45) 12:45-13:30 S18 S19 S20 Students’ Session: The biology of viruses Neeta Shrestha: Further analysis of the functions of the Ov8.25 region of OvHV2 Francesca Franzoso: Mechanisms of interactions of adeno-associated adenovirus and herpes simplex virus 1 in coinfected cells Can Altunbulakli: Role of rhinovirus in asthma exacerbations and regulation of epithelial barrier integrity Coffee Break (13:30-14:00) 14:00-14:45 P05 14:45-16:15 W01 Federica Sallusto (Intro: Hans Winkler): Studies on human T-cell response: Differentiation, migration and function Hauke Hennecke & Tobias Erb: Workshop on Scientific Integrity Transfer to ETH Main Building 17:15-18:00 W02 Alexander Wiedenmann (R&D Scientist, Pieris AG, Germany) From the Institute of Microbiology to therapeutic proteins Room HG E 41, ETH Main Building 18:15-22:15 MIM New Year’s Reception (“MIM Apéro”) Dozentenfoyer ETH Main Building, J-Floor Wednesday 15th 09:15-10:15 S21 S22 S23 S24 Students’ Session: The biology of T-cells Sarah Gabriel: Apoptosis Modulation in T cells for induction of allotolerance Daniela Jaramillo: Differential dendritic cell activation in peripheral T cell tolerance Tobias Wolf: Metabolism and T-cell differentiation Corinne De Gregorio: Studies on T cell activation, differentiation and plasticity in humans Morning Break (10:15-10:30) 10:30-11:15 S25 S26 S27 Students’ Session: Novel approaches to understand infections and resistance Kai Bao: Novel organotypic modeling for the study of periodontal infection Sun Lei: When drugs meet resistances: managing MDR in sequential vs combination multidrug therapy Athmanya Eshwar: Zebrafish larvae as a model host for real time analysis of infection with the opportunistic pathogen Cronobacter spp Lunch Break (11:15-12:45) 12:45-13:30 S28 S29 S30 Students’ Session: Immune reaction(s) Eva Guiducci: NK cell-mediated immunity against fungal infection Marina Tusup: Immunomodulation by exogenous RNA: Fundamental and translational studies Vanessa Mordasini: Impact of OM-85 on innate and adaptive immunity in tonsil Coffee Break (13:30-14:00) 14:00-14:45 P06 14:45-15:30 P07 Hans-Martin Fischer (Intro: Angela Suppiger): Regulatory principles in nitrogen fixing symbiosis Markus Seeger (Intro: Katja Becker): Bacterial drug efflux pumps: Their structure, mechanism and physiology Coffee Break (15:30-16:00) 16:00-16:45 P08 16:45-17:30 P09 Lisa Maier (Intro: Anna Karagianni): Microbiota-derived hydrogen fuels Salmonella Typhimurium invasion of the gut ecosystem Sai Reddy (Intro: Vural Yilmaz): Systems and synthetic biology methods applied to immunology Thursday 16th 09:15-10:15 S31 S32 S33 S34 Students’ Session: HIV - Understanding the virus and its adaptions Nottania Kay Campbell: Next Generation Sequencing (NGS) Analysis of HIV-1 Clinical Samples David Beauparlant: Functional adaptation of HIV-1 during disease progression Audrey Fahrny: Characterization of HIV latency in humanized mice infected with HIV‐1 and potential therapeutic interventions for HIV’s eradication Hanna Ebner: The evolution of broadly neutralizing antibodies in HIV infection Morning Break (10:15-10:30) 10:30-11:15 S35 S36 S37 Students’ Session: Understanding & manipulating secondary metabolite biosynthesis Silke Reiter: In vivo studies with trans-AT polyketid synthases Katja Jensen: New chain release and halogenation mechanisms in polyketide biosynthesis Dominik Peter: Substrate Promiscuity of crotonyl-CoA carboxylase / reductase and Homologs Lunch Break (11:15-12:45) 12:45-13:30 S38 S39 S40 Students’ Session: Bacterial virulence factors Anna Sophie Bahlmann: Factors modulating adherence of streptococci to host cell Rebekka Bauer: Virulence factor screening in Salmonella Typhimurium Anna Karagianni: Characterization of mycobacterial resistance and virulence factors Transfer to Zurich Main Station 14:00-16:00 Foxtrail: "Switzerland most thrilling paper chase” (http://www.foxtrail.ch/en-us) Afterwards: A hot chocolate (and beer…) at the bQm café & bar ETH Main Buildin, Polyterrasse Friday 17th 09:15-10:15 S41 S42 S43 S44 Students’ Session: Inflammation & immune system mediated diseases Barbara Meier: Investigation of very early events in the pathogenesis of psoriasis Carla Sellés Moreno: Sleep and the clock system in inflammatory bowel disease Marina Sabaté Brescó: Role of implant stability and local inflammatory response upon the development of infection associated with internal fixation devices Jeannette Kast: South African - Swiss - mechanisms of the development of allergy Morning Break (10:15-10:30) 10:30-11:15 S45 S46 S47 11:15-11:45 Students’ Session: Cell traffic: Entering & leaving eukaryotic cells Christian Keller: Autophagy-mediated antigen presentation for CD1drestricted NKT cell recognition Monica Loi: Regulation of MHC class I endocytosis by the macroautophagy machinery Branislav Ivan: The HIV envelope trimer: Dissecting molecular properties governing entry & antibody shielding Closing remarks: Leo Eberl For course feedback and evaluation please go online The questionnaire will be accessible on Friday, 17th via: http://www.klicker.uzh.ch/fni List of Participants NAME & INSTITUTION (ETH/Uni) E-MAIL – ADRESS Altunbulakli Bahlmann Bao Bauer Beauparlant Becker Brambilla Pisoni Campbell Cheng Costa Crameri De Gregorio Dirren Ebner Eshwar Eyring Fahrny Fenini Franzoso Gabriel Granato Guiducci Ivan Jaramillo Jensen Karagianni Kast Keller [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] Can Anna Sophie Kai Rebekka David Katja Giorgia Nottania Kay Hung-Wei Rita Michel Corinne Sebastian Hanna Athmanya Jillianne Audrey Gabriele Francesca Sarah Elisa Eva Branislav Daniela Katja Anna Jeannette Christian ETH UZH UZH ETH UZH UZH ETH UZH ETH UZH UZH ETH UZH UZH UZH ETH UZH UZH UZH UZH UZH ETH UZH ETH ETH UZH UZH UZH Lading Lei Loi Meier Mörbe Mordasini Novkovic Ochsner Peter Reiter Sabaté Brescó Sellés Moreno Shrestha Suppiger Tusup Winkler Wolf Yilmaz Zumthor Corinna Sun Monica Barbara Urs Vanessa Mario Andrea Dominik Silke Marina Carla Neeta Angela Marina Hans Tobias Vural Jon Paulin ETH ETH UZH UZH ETH UZH ETH ETH ETH ETH UZH UZH UZH UZH UZH UZH ETH ETH ETH [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] Introductory Course Planning and Organization: Judith Zingg, MIM PhD Program Coordinator ETH Zurich, Institute of Microbiology, Vladimir-Prelog-Weg 1-5/10, HCI G 429 CH - 8093 Zurich, Switzerland, Phone: +41 44 632 04 06 [email protected] Dr. Tobias J. Erb ETH Zurich, Institute of Microbiology, Vladimir-Prelog-Weg 1-5/10, HCI F 437 CH - 8093 Zurich, Switzerland, Phone: +41 44 632 36 54 [email protected] IT-Team of the Institute of Microbiology, ETH Zurich (Technical Support)
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