Prof. Annegret Kuhn, M.D., MBA
Publication List (selection since 2010)
1. Original Articles (selection since 2010)
1)
Schmitt V, Meuth AM, Amler S, Kuehn E, Haust M, Messer G, Bekou V, Sauerland C,
Köpcke W, Bonsmann G, Kuhn A. Lupus erythematosus tumidus is a separate subtype
of cutaneous lupus erythematosus.
Brit J Dermatol 2010; 162, 64-73. [Impact Factor: 4.100]
2)
Klein S, Kretz K, Krammer PH, Kuhn A. CD127low/- and FoxP3+ expression levels
characterize different regulatory T-cell populations in human peripheral blood.
J Invest Dermatol 2010; 130, 492-499. [Impact Factor: 6.372]
3)
Kuhn A, Haust M, Ruland V, Weber R, Verde P, Felder G, Gensch K, Ohmann C,
Ruzicka T. Effect of bosentan on skin fibrosis in patients with systemic sclerosis: A
prospective, open-label, non-comparative trial.
Rheumatology 2010; 49, 1336-1345. [Impact Factor: 4.435]
4)
Loser K, Vogl T, Voskort M, Lüken A, Kupas V, Nacken W, Klenner L, Kuhn A, Föll D,
Sorokin L, Luger TA, Roth J, Beissert S. The toll-like receptor 4 ligands Mrp8 and Mrp14
are crucial in the development of autoreactive CD8+ T cells.
Nat Med 2010; 16, 713-717. [Impact Factor: 28.054]
5)
Mosca M, Tani C, Aringer M, Bombardieri S, Boumpas D, Brey R, Cervera R, Doria A,
Jayne D, Khamashta MA, Kuhn A, Gordon C, Petri M, Rekvig OP, Schneider M, Sherer
Y, Shoenfeld Y, Smolen JS, Talarico R, Tincani A, van Vollenhoven RF, Ward MM, Werth
VP, Carmona L. EULAR Recommendations for monitoring patients with systemic lupus
erythematosus in clinical practice and in observational studies.
Ann Rheum Dis 2010; 69, 1269-1274. [Impact Factor: 9.270]
6)
Meuth A, Amler S, Haust M, C Sauerland, Köpcke W, Bonsmann G, Nyberg F, Kuhn A. A
database analysis of cutaneous lupus erythematosus with the EUSCLE Core Set
Questionnaire.
Acta Derm Venereol 2010, 90: 386-394. [Impact Factor: 4.244]
7)
Kuhn A, Meuth A, Bein D, Amler S, Beissert S, Böhm M, R Brehler, J Ehrchen, S
Grundmann, M Haust, V Ruland, M Schiller, P Schulz, S Ständer, C Sauerland, Köpcke
W, Luger TA, Bonsmann G. Revised Cutaneous Lupus Erythematosus Disease Area and
Severity Index (RCLASI): A modified outcome instrument for cutaneous lupus
erythematosus.
Brit J Dermatol 2010; 163, 83-92. [Impact Factor: 4.100]
Prof. Dr. med. Annegret Kuhn, MBA
8)
Publication List (selection since 2010)
Kretz CC, Norpo M, Abeler-Dörner L, Linke B, Haust M, Edler L, Krammer PH, Kuhn A.
Anti-annexin 1 antibodies: A new diagnostic marker in the serum of patients with discoid
lupus erythematosus.
Exp Dermatol 2010; 19, 919-921. [Impact Factor: 4.115]
9)
Antiga E, Kretz CC, Klembt R, Massi D, Ruland V, Stumpf C, Baroni G, Hartmann M,
Hartschuh W, Volpi W, Del Bianco E, Enk A, Fabbri P, Krammer PH, Caproni M, Kuhn A.
Characterization of regulatory T cells in patients with dermatomyositis.
J Autoimmun 2010; 35, 342-50. [Impact Factor: 7.018]
10) Kuhn A, Gensch T, Haust M, Meuth AM, Boyer F, Dupuy P, Lehmann P, Metze D,
Ruzicka T. Photoprotective effects of a broad-spectrum sunscreen in UV-induced
cutaneous lupus erythematosus: A randomized, vehicle-controlled, double-blind study.
J Am Acad Dermatol 2011; 64, 37-48. [Impact Factor: 5.004]
11) Naschberger E, Wenzel J, Kretz CC, Herrmann M, Stürzl M, Kuhn A. Increased
expression of guanylate binding protein-1 in lesional skin of patients with cutaneous lupus
erythematosus.
Exp Dermatol 2011; 20, 102-106. [Impact Factor: 4.115]
12) Mosca M, Tani C, Aringer M, Bombardieri S, Boumpas D, Cervera R, Doria A, Jayne D,
Khamashta MA, Kuhn A, Gordon C, Petri M, Schneider M, Shoenfeld Y, Smolen JS,
Talarico R, Tincani A, Ward MM, Werth VP, Carmona L. Development of quality indicators
to evaluate the monitoring of SLE patients in routine clinical practice.
Autoimmun Rev 2011; 10, 383-388. [Impact Factor: 7.095]
13) Bein D, Kuehn E, Meuth AM, Amler S, Haust M, Nyberg F, Sauerland C, Luger TA,
Bonsman G, Kuhn A. Evaluation of disease activity and damage in different subtypes of
cutaneous lupus erythematosus using the CLASI.
J Eur Acad Dermatol Venereol 2011; 25, 652-659. [Impact Factor: 3.105]
14) Kuhn A, Gensch K, Haust M, Schneider SW, Bonsmann G, Gaebelein-Wissing N,
Lehmann P, Wons A, Reitmeir P, Ruland V, Luger TA, Ruzicka T. Efficacy of tacrolimus
0.1% ointment in cutaneous lupus erythematosus - A multicenter, randomized, doubleblind, vehicle-controlled trial.
J Am Acad Dermatol 2011; 65, 54-64. [Impact Factor: 5.004]
15) Klein S, Kretz CC, Ruland V, Stumpf C, Haust M, Hartschuh W, Hartmann M, Enk A, SuriPayer E, Oberle N, Krammer PH, Kuhn A. Reduction of regulatory T cells in skin lesions
but not in peripheral blood of patients with systemic scleroderma.
Ann Rheum Dis 2011; 70, 1475-1481. [Impact Factor: 9.270]
Page 2 of 8
Prof. Dr. med. Annegret Kuhn, MBA
Publication List (selection since 2010)
16) Kuhn A, Wozniacka A, Szepietowski JC, Gläser R, Lehmann P, Haust M, SysaJedrzejowska A, Reich A, Oke V, Hügel R, Calderon C, de Vries DE, Nyberg F.
Photoprovocation in cutaneous lupus erythematosus: A multicenter study evaluating a
standardized protocol.
J Invest Dermatol 2011; 131, 1622-1630. [Impact Factor: 6.372]
17) Toberer F, Sykora J, Göttel D, Ruland V, Hartschuh W, Enk A, Luger TA, Beissert S, Loser
K, Joos S, Krammer PH, Kuhn A. Tissue microarray analysis of RANKL in cutaneous
lupus erythematosus and psoriasis.
Exp Dermatol 2011; 20, 600-602. [Impact Factor: 4.115]
18) Kuhn A, Patsinakidis N, Luger TA. Alitretinoin for cutaneous lupus erythematosus.
J Am Acad Dermatol 2012; 67, 123-126. [Impact Factor: 5.004]
19) Mierau R, Moinzadeh P, Riemekasten G, Melchers I, Meurer M, Reichenberger F, Buslau
M, Worm M, Blank N, Hein R, Müller-Ladner U, Kuhn A, Sunderkotter C, Juche A,
Pfeiffer C, Fiehn C, Sticherling M, Lehmann P, Stadler R, Schulze-Lohoff E, Seitz C,
Foeldvari I, Krieg T, Genth E, Hunzelmann N. Frequency of disease associated and other
nuclear autoantibodies in patients of the German network for systemic scleroderma:
correlation with caracteristic clinical features.
Arthritis Res Ther 2012; 13, R172. [Impact Factor: 4.117]
20) Patsinakidis N, Wenzel J, Landmann A, Koch R, Gerß J, Luger TA, Metze D, Surber C,
Kuhn A. Suppression of UV-induced damage by a liposomal sunscreen: A prospective,
open-label study in patients with cutaneous lupus erythematosus and healthy controls.
Exp Dermatol 2012; 21, 958-961. [Impact Factor: 4.115]
21) Groth S, Vafia K, Recke A, Dähnrich C, Zillikens D, Stöcker W, Kuhn A, Schmidt E.
Antibodies to the C-terminus of laminin γ1 are present in a distinct subgroup of patients
with systemic and cutaneous lupus erythematosus.
Lupus 2012; 21, 1482-1483. [Impact Factor: 2.481]
22) Ruland V, Haust M, Stilling R, Amler S, Ruzicka T, Kuhn A. Updated analysis of
standardised photoprovocation in patients with cutaneous lupus erythematosus.
Arthritis Care Res 2013; 65, 767-776. [Impact Factor: 3.731]
23) Sigges J, Biazar C, Landmann A, Ruland V, Patsinakidis N, Amler S, Bonsmann G, Kuhn
A, and the EUSCLE Co-Authors. Therapeutic strategies evaluated by the European
Society of Cutaneous Lupus Erythematosus (EUSCLE) Core Set Questionnaire in more
than 1000 patients with cutaneous lupus erythematosus.
Autoimmun Rev 2013; 12, 694-702. [Impact Factor: 7.095]
Page 3 of 8
Prof. Dr. med. Annegret Kuhn, MBA
Publication List (selection since 2010)
24) Biazar C, Sigges J, Patsinakidis N, Ruland V, Amler S, Bonsmann G, Kuhn A, and the
EUSCLE Co-Authors. Cutaneous lupus erythematosus: First multicentre database
analysis of 1002 patients from the European Society of Cutaneous Lupus Erythematosus
(EUSCLE).
Autoimmun Rev 2013; 13, 444-54. [Impact Factor: 7.095]
25) Abeler-Dörner L, Kretz CC, Berger B, Weyd H, Gräf D, Pfrang S, Tarner I, Schwarting A,
Lorenz HM, Müller-Ladner U, Krammer PH, Kuhn A. IFN-α abrogates the suppressive
effect of apoptotic cells on dendritic cells in an in vitro model of SLE pathogenesis.
J Rheumatol 2013; 40, 1683-1696. [Impact Factor: 3.173]
26) Szepietowski JC, Nilganuwong S, Wozniacka A, Kuhn A, Nyberg F, Szechiński J, van
Vollenhoven RF, Bengtsson AA, Reich A, de Vries DE, van Hartingsveldt B, Robinson D,
Gordon R, Hsu B. Phase 1, randomized, double-blind, placebo-controlled, multiple IV,
dose-ascending study of sirukumab in cutaneous or systemic lupus erythematosus.
Arthritis Rheum 2013; 65, 2661-2671. [Impact Factor: 7.871]
27) Toberer F, Sykora J, Göttel D, Hartschuh W, Werchau S, Enk A, Joos S, Krammer PH,
Kuhn A. Apoptotic Signal Molecules in Skin Biopsies of
Cutaneous Lupus
Erythematosus: Analysis Using Tissue Microarray.
Exp Dermatol 2013; 22, 656-659. [Impact Factor: 4.115]
28) Van Vollenhoven R, Mosca M, Bertsias G, Isenberg D, Kuhn A, Lerstrom K, Aringer M,
Bootsma H, Boumpas D, Bruce I, Cervera R, Clarke A, Costedoat-Chalumeau N, Czirják
L, Derksen R, Dörner T, Gordon C, Graninger W, Houssiau F, Jacobsen S, Jayne D,
Jedryka-Goral A, Inanc M, Levitsky A, Levy R, Mariette X, Morand E, Navarra S,
Neumann I, Rahman A, Rovenský J, Smolen J, Vasconcelos C, Voskuyl A, Voss A,
Zakharova E, Zoma A, Schneider M. Treat-to-target in systemic lupus erythematosus:
recommendations from an international task force.
Ann Rheum Dis 2014; 73, 958-967. [Impact Factor: 9.270]
29) Tsianakas A, Herzog S, Landmann A, Patsinakidis N, Perusquía Ortiz AM, Bonsmann G,
Luger TA, Kuhn A. Successful treatment of discoid lupus erythematosus with fumaric
acid esters.
J Am Acad Dermatol 2014; 71, e15-e17. [Impact Factor: 5.004]
30) Kuhn A, Sigges J, Biazar C, Ruland V, Patsinakidis N, Landmann A, Amler S, Bonsmann
G. Influence of smoking on disease severity and antimalarial therapy in cutaneous lupus
erythematosus: Analysis of 1002 patients of the EUSCLE database.
Brit J Dermatol 2014; 171, 571-579. [Impact Factor: 4.100]
Page 4 of 8
Prof. Dr. med. Annegret Kuhn, MBA
Publication List (selection since 2010)
31) Zahn S, Graef M, Patsinakidis N, Landmann A, Surber C, Wenzel J, Kuhn A. Ultraviolet
light protection by a sunscreen prevents interferon-driven skin inflammation in cutaneous
lupus erythematosus.
Exp Dermatol 2014; 23, 516-518. [Impact Factor: 4.115]
32) Günther C, Kind B, Reijns MA, Berndt N, Martinez-Bueno M, Wolf C, Tüngler V, Chara O,
Lee YA, Hübner N, Bicknell L, Blum S, Krug C, Schmidt F, Kretschmer S, Koss S, Astell
KR, Ramantani G, Bauerfeind A, Morris DL, Cunninghame Graham DS, Bubeck D, Leitch
A, Ralston SH, Blackburn EA, Gahr M, Witte T, Vyse TJ, Melchers I, Mangold E, Nöthen
MM, Aringer M, Kuhn A, Lüthke K, Unger L, Bley A, Lorenzi A, Isaacs JD, Alexopoulou D,
Conrad K, Dahl A, Roers A, Alarcon-Riquelme ME, Jackson AP, Lee-Kirsch MA.
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity.
J Clin Invest 2015; 125: 413-424. [Impact Factor: 13.765]
33) Isenberg D, Gordon C, Licu D, Copt S, Rossi CP, Wofsy D, and co-authors. Efficacy and
safety of atacicept for prevention of flares in patients with moderate-to-severe systemic
lupus erythematosus (SLE): 52-week data (APRIL-SLE randomised trial).
Ann Rheum Dis 2015; in press. [Impact Factor: 10.377]
34) Kunz M, König I, Schillert A, Kruppa J, Ziegler A, Grallert H, Müller-Nurasyid M, Lieb W,
Franke A, Ranki A, Panelius J, Koskenmies S, Hasan T, Kere J, Rönn AC, Simon J,
Schmidt E, Wenzel J, Tüting T, Landsberg J, Zeller T, Blankenberg S, Gläser R,
Patsinakidis N, Kuhn A, Ibrahim S.
Genome-wide association study identifies new susceptibility loci for cutaneous lupus
erythematosus.
Exp Dermatol 2015; in press. [Impact Factor: 4.115]
35) Calderon C, Zucht HD, Kuhn A, Wozniacka A, Szepietowski JC, Nyberg F, Weichenthal
M, Piantone A, Budde P. A multicenter photoprovocation study to identify potential
biomarkers by global peptide profiling in cutaneous lupus erythematosus.
Lupus 2015; in press. [Impact Factor: 2.197]
2. Review Articles (selection since 2010)
1)
Aringer M, Kuhn A. Gibt es wirklich einen kutanen Lupus erythematodes?
Z Rheumatol 2010; 69, 389-392. [Impact Factor: 0.456]
2)
Kuhn A, Patsinakidis N, Bonsmann G. The Impact of the EUSCLE Core Set
Questionnaire for the assessment of cutaneous lupus erythematosus.
Lupus 2010; 19, 1144-1152. [Impact Factor: 2.481]
Page 5 of 8
Prof. Dr. med. Annegret Kuhn, MBA
3)
Publication List (selection since 2010)
Kuhn A, Ruland V, Bonsmann G. Photosensitivity, phototesting, and photoprotection in
cutaneous lupus erythematosus.
Lupus 2010; 19, 1036-1046. [Impact Factor: 2.481]
4)
Kuhn A, Ochsendorf F, Bonsmann G. Treatment of cutaneous lupus erythematosus.
Lupus 2010; 19, 1125-1136. [Impact Factor: 2.481]
5)
Kuhn A, Ruland V, Bonsmann G. Lupus erythematosus tumidus: A separate subtype in
the classification of cutaneous lupus erythematosus - reply from authors.
Brit J Dermatol 2010; 163, 231-232. [Impact Factor: 4.100]
6)
Kuhn A, Luger TA. Is ustekinumab superior over etanercept in the treatment of psoriasis?
Nat Rev Rheumatol 2010; 6, 500-501. [Impact Factor: 10.252]
7)
Kuhn A, Ruland V, Patsinakidis N, Luger TA. Use of methotrexate in patients with
psoriasis.
Clin Exp Rheumatol 2010; 28, S138-144. [Impact Factor: 2.973]
8)
Kuhn A, Ruland V, Bonsmann G. Measuring disease activity and damage in cutaneous
lupus erythematosus - reply from authors.
Brit J Dermatol 2010; 164, 222-224. [Impact Factor: 4.100]
9)
Kuhn A, Ruland V, Bonsmann G. Cutaneous lupus erythematosus - Update of
therapeutic options (Part 1).
J Am Acad Dermatol 2011; 65, e179-e193. [Impact Factor: 5.004]
10) Kuhn A, Ruland V, Bonsmann G. Cutaneous lupus erythematosus - Update of
therapeutic options (Part 2).
J Am Acad Dermatol 2011; 65, e195-e213. [Impact Factor: 5.004]
11) Kuhn A, Ruland V, Bonsmann G. Hautmanifestationen des Lupus erythematodes. CME
Weiterbildungsartikel.
Z Rheumatol 2011; 70, 213-227. [Impact Factor: 0.456]
12) Sárdy M, Ruzicka T, Kuhn A. Topical glucocorticoids and calcineurin inhibitors in
cutaneous lupus erythematosus.
J Clin Dermatol 2011; Epub. [kein Impact Factor]
13) Riemekasten G, Hellmich B, Hoffmann U, Sunderkötter C, Weiss N, Kuhn A.
Management digitaler Ulzera bei Patienten mit systemischer Sklerose.
Dtsch Med Wochenschr 2012; 137, 34-40. [Impact Factor: 0.550]
Page 6 of 8
Prof. Dr. med. Annegret Kuhn, MBA
Publication List (selection since 2010)
14) Mrowietz U, Adamczyk A, Altmeyer P, Augustin M, Boehncke W H, Bonnekoh B,
Frambach Y, Gambichler T, Ghoreschi K, Hertl M, Hund A C, Jacobi A, Kuhn A, Lippert
U, Ludwig R, Luger T, Martin S F, Merk H, Norgauer J, Reich K, Rostami-Yazdi M, Sabat
R, Schäkel K, Scharffetter-Kochanek K, Schön M P, Scola N, Sticherling M, Thaci D,
Viehweg A, Wilsmann-Theis D, Zouboulis C C, Neureither M. Neue Erkenntnisse zu
Fumarsäureestern (Fumaderm®): Ergebnisse des 2. Experten-Workshops.
J Dtsch Dermatol Ges 2012; 10, 1-15. [Impact Factor: 1.815]
15) Kuhn A, Landmann A, Bonsmann G. Der kutane Lupus erythematodes. CME
Weiterbildungsartikel.
Akt Dermatol 2012; 39, 36-52. [kein Impact Factor]
16) Kuhn A, Landmann A. The classification and diagnosis of cutaneous lupus
erythematosus.
J Autoimmun 2014; 48-49, 14-19 [Impact Factor: 7.018]
17) Kuhn A, Wenzel J, Weyd H. Photosensitivity, Apoptosis and Cytokines in the
Pathogenesis of Cutaneous Lupus Erythematosus: A Critical Review.
Clin Rev Allergy Immunol 2014; 47, 148-162. [Impact Factor: 4.728]
18) Schultz HY, Dutz JP, Furukawa F, Goodfield MJ, Kuhn A, Lee LA, Nyberg F,
Szepietowski JC, Sontheimer RD, Werth VP. From Pathogenesis, Epidemiology, and
Genetics to Definitions, Diagnosis, and Treatments of Cutaneous Lupus Erythematosus
and Dermatomyositis: A Report from the 3rd International Conference on Cutaneous
Lupus Erythematosus (ICCLE) 2013.
J Invest Dermatol 2015; 135, 7-12. [Impact Factor: 6.372]
19) Kuhn A, Bonsmann G, Anders HJ, Herzer P, Tenbrock K, Schneider M. Diagnostik und
Therapie des systemischen Lupus erythematodes.
Dtsch Arztebl 2015; 19, 112, 423-32. [Impact Factor: 3.542]
20) Kuhn A, Wenzel J, Bijl M. Lupus erythematosus revisited.
Semin Immunopathol 2015; in press. [Impact Factor: 7.748]
3. Book Chapters (selection since 2010)
1)
Kuhn A, Böhm M, Luger TA. Tissue injury and the skin.
In: Lahita R, Buyon J, Koike T, Tsokos G. Systemic Lupus Erythematosus. 5th Edition.
Elsevier, New York, USA, 2010; 475-490.
2)
Kuhn A, Haust M, Bonsmann G. Klinik und Therapie von SLE Hautmanifestationen.
In: Aringer M. Aktuelle Therapieoptionen beim systemischen Lupus erythematodes.
Page 7 of 8
Prof. Dr. med. Annegret Kuhn, MBA
Publication List (selection since 2010)
2. Aufl., Unimed Verlag, Bremen, 2011; pp 56-63.
3)
Kuhn A. Muzinosen.
In: Plewig G, Landthaler M, Burgdorf W, Ruzicka T. Braun-Falco’s Dermatologie,
Venerologie und Allergologie, 6. Aufl., Springer-Verlag, Heidelberg, 2012; 1540-1547.
4)
Kuhn A, Sticherling M. Lupus erythematodes.
In: Plewig G, Landthaler M, Burgdorf W, Ruzicka T. Braun-Falco’s Dermatologie,
Venerologie und Allergologie, 6. Aufl., Springer-Verlag, Heidelberg, 2012; 866-882.
5)
Kuhn A, Aberer E, Aringer M, Gläser R, Kreuter A, Ochsendorf F, Sardy M, Sticherling M,
Varga R, Wenzel J, Wittmann E, Wozel J. Lupus Erythematodes.
In: Burg G, Gollnick H. Dermokrates eHandbuch, 2013; online.
6)
Aringer M, Kuhn A. Skin manifestations of systemic lupus erythematosus.
In: Matucci-Cerinic M, Warren P. Rheumatic Diseases and the Skin, 1st Edition, Elsevier,
New York, USA, 2013; 217-230.
7)
Kuhn A. Lupus erythematodes.
In: Stebut-Borschitz E, Steinbrink K, Berneburg M, Maurer M. Buchreihe Facharztprüfung.
Georg Thieme Verlag KG, Stuttgart, 2014; 169-173.
8)
Kuhn A, Haust M, Bonsmann G. Klinik und Therapie von SLE Hautmanifestationen.
In: Aringer M. Aktuelle Therapieoptionen beim systemischen Lupus erythematodes. 3.
Aufl., Unimed Verlag, Bremen, 2014; 63-71.
9)
Kuhn A, Landmann A. Lupus erythematosus.
In: Katsambas A, Lotti T, Dessinioti C, Massimilano A. European Handbook of
Dermatological Treatment. Springer Verlag, Heidelberg, 2015; 547-560.
10) Kuhn A, Sunderkötter C, Bonsmann G. Raynaud-Syndrom und akrale Ischämiesyndrome.
In: Müller-Ladner U. Dermatologische Differentialdiagnostik kutaner Durchblutungsstörungen. 3. Aufl., Unimed Verlag, Bremen, 2015; in press.
11) Kuhn A, Landmann A. Advances in therapy of cutaneous lupus erythematosus.
In: van Vollenhoven R. Clinical Therapy Research in the Inflammatory Diseases. 1st
Edition World Scientific Publishing, Singapore, 2015; in press.
12) Kuhn A, Landmann A, Bonsmann G. Skin in SLE.
In: Tsokos GC, Encyclopedia of Medical Immunology. Vol 1: Autoimmune Diseases. 1st
Edition, Springer Verlag, Heidelberg, Berlin, New York, Bremen, 2015; in press.
Page 8 of 8

Esther Kuehn, PhD - Aging & Cognition Research Group

17_01_22_ZVR_Zillertal Arena_Results