Hoshi University 氏 名 服部 所 属 医療薬剤学教室 学 位 博士(薬学) 最終学歴 教育活動 (担当授業科目) 喜之 職 位 准教授 京都大学大学院薬学研究科博士課程修了 バイオ医薬品とゲノム情報 (第 3 学年前期・専任) 生体分子の立体構造と相互作用 DDS (第 3 学年後期・分担) (第 4 学年前期・分担) 臨床薬剤学特論 I (大学院・分担・隔年) 製剤学実習 (第 3 学年後期・分担 ) 研究活動 (研究テーマ) 所属学会 がん治療のための非ウイルス性遺伝子ベクターの 開発 日本薬学会、日本 DDS 学会、日本薬剤学会、日本癌学会、 遺伝子デリバリー研究会 学内活動 アドバンスト実務実習委員会委員 (役職・委員等) 入試実行委員会委員( 入試準備室 副長) 学外活動 (委員会委員等) Editorial Board Member of Journal of Pharmaceutics 研究業績等 (受賞歴) 平成 11 年 米国甲状腺学会 Travel Grant 受賞, 平成 13 年 日本内分泌学会若手研究奨励賞受賞 平成 21 年 星薬科大学 大谷記念研 究助成金受賞, 平成 21 年 日本薬学会関東支部奨励賞 受賞 (主な論文) 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. HATTORI, Y. AND MAITANI, Y.: Folate-linked nanoparticle-mediated suicide gene therapy in human prostate cancer and nasopharyngeal cancer with herpes simplex virus thymidine kinase . Cancer Gene Ther., 12, 796-809 (2005) HATTORI, Y., KUBO, H., HIGASHIYAMA, K. AND MAITANI, Y.: Folate-linked nanoparticles formed with DNA complexes in sodium chloride solution enhance transfection efficiency, J. Biomed. Nanotechnol., 1, 176-184 (2005) (IF =7.578) HATTORI, Y. AND MAITANI, Y.: Folate-linked lipid-based nanoparticle for targeted gene delivery, Current Drug Delivery, 2, 243-252 (2005) HATTORI, Y., SAKAGUCHI, M. AND MAITANI, Y.: Folate-linked lipid-based nanoparticles deliver a NFB decoy into activated murine macrophage-like RAW264.7 cells, Biol. Pharm. Bull., 29, 1516-1520 (2006) HATTORI, Y. AND MAITANI, Y.: Two-step transcriptional amplification-lipid-based nanoparticles using PSMA or midkine promoter for suicide gene therapy in prostate cancer, Cancer Science, 97, 787-798 (2006) HATTORI, Y., DING, W. AND MAITANI, Y.: Highly efficient cationic hydroxyethylated cholesterol -based nanoparticle-mediated gene transfer in vivo and in vitro in prostate carcinoma PC-3 cells, J Control. Release, 120, 122-130 (2007) (IF =7.261) HATTORI, Y., FUKUSHIMA, M. AND MAITANI, Y.: Non-viral delivery of connexin 43 gene with histone deacetylase inhibitor to human nasopharyngeal tumor cells enhances gene expression and inhibits in vivo tumor growth, Int. J. Oncology, 30, 1427- 1439 (2007) HATTORI, Y., HAGIWARA, A., DING, W. AND MAITANI, Y.:, NaCl improves siRNA delivery mediated by nanoparticles of hydroxyethylated cationic cholesterol with amido -linker, Bioorganic & Medicinal Chemistry letters, 18, 5228-5232 (2008) HATTORI, Y., YOSHIZAWA, T., KOGA, K., AND MAITANI, Y.: NaCl induced high cationic hydroxyethylated cholesterol-based nanoparticle-mediated synthetic siRNA transfer into prostate carcinoma PC-3 cells, Biol. Pharm. Bull., 31, 2294-2301 (2008) HATTORI, Y., SHI, L., DING, W., KOGA, K., KAWANO, K., HAKOSHIMA, M., AND MAITANI, Y.: Novel irinotecan-loaded liposome using phytic acid with high therapeutic efficacy for colon tumors, J. Control. Release, 136, 30-37 (2009) (IF =7.261) HATTORI, Y., HAKOSHIMA, M. KOGA K. AND MAITANI, Y.: Increase of therapeutic effect by treating nasopharyngeal tumor with combination of HER-2 siRNA and paclitaxel, Int. J. Oncology, 36, 1039-1046 (2010) HATTORI, Y., KANAMOTO, N., KAWANO, K., IWAKURA, H., SONE, M., MIURA, M., YASODA, A., TAMURA, N., ARAI, H., AKAMIZU, T., NAKAO, K. AND MAITANI, Y.: Molecular characterization of tumors from a transgenic mice adrenal tumor model: Comparison with human pheochromocytoma, Int. J. Oncology, 37, 695-705 (2010) HATTORI, Y., UBUKATA, H., KAWANO, K. AND MAITANI, Y.: Angiotensin II-induced hypertension enhanced therapeutic efficacy of liposomal doxorubicin in tumor-bearing mice, Int. J. Pharm., 403, 178-184 (2011) HATTORI, Y., NAKAMURA, T., OHNO, H., FUJII, N.,AND MAITANI, Y.: siRNA delivery for tumor by lipid-based nanoparticle composed with hydroxyethylated cholesteryl triamine , Int. J. Pharm.,443:221-229 (2013). HATTORI, Y., YAMASAKU, H. AND MAITANI, Y.: Anionic polymer-coated lipoplex for safe gene delivery into tumor by systemic injection, J. Drug Target., 21(7): 639-647 (2013) HATTORI, Y., ARAI, S., OKAMOTO, R., HAMADA, M., KAWANO, K. AND YONEMOCHI, E.: Sequential intravenous injection of anionic polymer and cationic lipoplex of siRNA could effectively deliver siRNA to the liver, Int J Pharm., 476: 289-298 (2014) (分担著書) 1. 2. 3. HATTORI, Y., AND MAITANI, Y.: Folate-linked lipid-based nanoparticles for tumor-targeted gene therapy, Nanotechnologies for the Life Science, Biofunctionalization of nanomaterials, edited by Challa. Kumar, Wiley-VCH, 1, 270-298 (2005) HATTORI, Y., AND MAITANI, Y.: Tumor-targeting non-viral gene therapy for the treatment of oral cancer, Oral Cancer Research Advances, edited by Alexios P. Nikolakakos, Nova Science Publishers, Inc. , 95-124 (2007) HATTORI, Y., AND MAITANI, Y.: Folate-linked lipid-based nanoparticle gene delivery to the tumor, Encyclopedia of Nanoscience and Nanotechnology, edited by H. S. Nalwa, American Scientific Publishers, 14, 263-277 (2011) 戻る→→ →
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