ဃ˳ὉҔၲἙἢỶἋဇ ឬࣱἊἽἅἝỸἲӳỉႆ ᵩᶃᶗᴾᵵᶍᶐᶂᶑ ಒ ᙲ Biomaterials, Shape Memory Alloys, Medical Devices ဃ˳ỆܤμễΨእỉỚỂನẰủẆឬࣱࣄׅപỚầᵲᶇᵋᵬᶇỆҒૣ ẴỦᵸᶐኒឬࣱӳửႆẲẺẇႆӳỊࢼஹỉᵬᶇᵋᶄᶐᶃᶃỉᵲᶇؕឬ ࣱӳợụᵑ̿ˌɥỉ࢟ཞࣄׅὉẲễởẦẰểΟủẺဃ˳ᢘӳࣱử ӳỪẶਤếẺỜҔၲἙἢỶἋဇឬࣱӳểẲềஊஓỂẝỦẇ ࢟ཞᚡচӳὉឬࣱӳ ឬࣱἊἽἅἝỸἲӳỉႆ Ṽ ࢟ཞᚡচјௐὉឬࣱ Ṽ ΟủẺኬᏘᢘӳࣱ ᙧ≧グ᠈䞉㉸ᙎᛶྜ㔠䛿⇕䜢ឤ▱䛩䜛䝉䞁䝃䞊ᶵ⬟ 䚸ຊ䛸ṍ䜏䜢Ⓨ⏕䛩䜛䜰䜽䝏䝳䜶䞊䝍䞊ᶵ⬟䚸ᙎᛶ㝈 䛜୍⯡㔠ᒓ䛾ᩘ༑ಸ䛾䇾㉸ᙎᛶ䇿䜢᭷䛧䚸ᕤᴗศ㔝䚸 ་⒪ศ㔝䚸ᐙ㟁〇ရ䚸᪥ᖖ⏝ရ䛺䛹䛾ᵝ䚻䛺ศ㔝䛷 ᖜᗈ䛟⏝䛥䜜䛶䛔䜛䚹 ⏕య䛻Ᏻ䛺ඖ⣲䛾䜏䛷ᵓᡂ䛥䜜䜛ྜ㔠タィ䛻䜘䜚 䚸ඃ䜜䛯⏕య㐺ྜᛶ䜢ᐇ⌧䚹䜎䛯䚸✀䚻䛾⣽⬊ᇵ㣴 ᐇ㦂䛻䜘䜚㼀㼕㻙㻺㼕䛻ẚ䜉ඃ䜜䛯⣽⬊㐺ྜᛶ䜢☜ㄆ䚹 ᙧ≧グ᠈ຠᯝ cell medium specimen ㉸ᙎᛶ incubated for 1d Zr-Ti-Nb-Sn 䠄㛤Ⓨྜ㔠䠅 incubated for 4-7d 1d 4d 7d 1d 4d 7d Ti-Ni WST-1 assay fixed and stained 䝠䝖㦵ⱆ⣽⬊ᵝ⣽⬊ ᰴᇵ㣴ᐇ㦂 ㈇Ⲵ ᚎⲴ Ṽ ΟủẺឬࣱཎࣱ Ṽ ࢟ཞᚡচὉឬࣱӳỉࣖဇ ㏆ᖺ䚸་⒪ᢏ⾡䛾㐍ᒎ䛻క䛔䚸ᙧ≧グ᠈䞉㉸ᙎᛶྜ 㔠䛾་⒪䝕䝞䜲䝇䛸䛧䛶䛾ᛂ⏝䛜༨䜑䜛ྜ䛿ᖺ䚻 ቑ䛧䛶䛔䜛䚹䛧䛛䛧䚸ᐇ⏝㉸ᙎᛶྜ㔠䛷䛒䜛㼀㼕㻙㻺㼕 ྜ㔠䛿ᙉ䛔䜰䝺䝹䜼䞊ᛶ䛸⣽⬊ẘᛶ䜢᭷䛩䜛㻺㼕䜢㧗 ⃰ᗘ䛷ྵ䜣䛷䛔䜛䚹 ᚑ᮶䛾⏕య⏝㼀㼕ᇶ㉸ᙎᛶྜ㔠䜘䜚㻟ಸ௨ୖ䛾㼀㼕㻙㻺㼕䛻 ༉ᩛ䛩䜛ᙧ≧ᅇ䞉䛧䛺䜔䛛䛥䜢ᐇ⌧䚹䛥䜙䛻䚸ඃ䜜 䛯෭㛫ຍᕤᛶ䚸㧗䛔㼄⥺㐀ᙳᛶ䜢᭷䛧䚸㻹㻾㻵䜰䞊䝏䝣 䜯䜽䝖䛾㜵Ṇ䛻䜒᭷ຠ䚹 Zr-Ti-Nb-Sn䠄㛤Ⓨྜ㔠䠅 ᙎᛶ㝈 Ti-Niྜ㔠 ⏕య㐺ྜᛶ ᙧ≧グ᠈ຠᯝ䛸 ㉸ᙎᛶ䛾ᶍᘧᅗ ᛂຊ(MPa) ㈇Ⲵ ᚑ᮶ Tiྜ㔠 㛤Ⓨ Zrྜ㔠 ᚑ᮶ Ti-Niྜ㔠 ㉸ᙎᛶᅇṍ䜏 ṍ䜏(%) ㉸ᙎᛶྜ㔠䛾 ་⒪ศ㔝䜈䛾 ᛂ⏝ 㛤Ⓨ㉸ᙎᛶྜ㔠䛸ᚑ᮶ ㉸ᙎᛶྜ㔠䛸䛾ẚ㍑ Ṽ ेܭẰủỦဇᡦ z 䝯䜺䝛䝣䝺䞊䝮䚸ṑิ▹ṇ䝽䜲䝲䞊䛺䛹⫙䛻┤᥋ ᥋ゐ䛩䜛་⒪ჾල䜔⏕ά⏝ရ z 䝪䞊䞁䝥䝺䞊䝖䜔䝛䝆䚸䜽䝸䝑䝥➼䛾ᅛᐃ⤖ྜ⏝䛾 ་⒪ჾල z 䜺䜲䝗䝽䜲䝲䞊䚸䝇䝔䞁䝖➼䛾యෆ䛻ᤄධ䞉␃⨨䛩 䜛་⒪ჾල ᇌܖٻඥʴ ሇඬ ܖٻૠྸཋឋኒ ཋឋ؏ܖ ་ಝ
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