DOI: 10.3179/jjmu. JJMU.A.49 ◇ ORIGINAL ARTICLE ◇ 日本人における下肢 加茂 健太1 西野 聖吾2 付着部の厚さの正常値の検討 松田 夕子2 川島 朝子2 吉本 智子2 抄 録 目的:脊椎関節炎(SpA)の早期診断と活動性の評価に腱付着部炎の超音波検査が用いられている.当科では下肢 腱付着部炎の超音波検査スコアである Glasgow ultrasound enthesitis scoring system(GUESS)を用いて,スクリー ニング,活動性の評価を行っている.GUESS では腱肥厚の閾値が設定されているが,日本人における腱の厚さの 正常値が不明である.日本人における大腿四頭筋腱付着部,膝蓋腱付着部(膝蓋骨側,脛骨側),アキレス腱付着部, 足底腱膜付着部の腱の厚さの正常値を明らかにすることを目的とした.対象と方法:2014 年 6 月から 2015 年 5 月 の間に,SpA の GUESS による評価を目的として超音波検査を施行した 77 名(770 部位)の中で,圧痛のない部 位を対象とした.炎症性腸疾患,乾癬,SpA や関節リウマチなど膠原病,X線靭帯骨棘を認める症例を除外した. 結果と考察:大腿四頭筋腱付着部 41 膝,膝蓋腱膝蓋骨付着部では 58 膝,膝蓋腱脛骨腱付着部 53 膝,アキレス腱 付着部 24 足, 足底腱膜付着部 39 足が健常群となった.大腿四頭筋腱付着部の厚さは, 5. 11 mm(95% CI 4. 88 - 5. 34, p < 0. 01),膝蓋腱膝蓋骨付着部の厚さは,3. 25 mm(95% CI 3. 08 - 3. 43,p < 0. 01),膝蓋腱脛骨腱付着部の厚さ は, 3. 84 mm(95% CI 3. 64 - 4. 05,p < 0. 01),アキレス腱付着部の厚さは,4. 16 mm(95% CI 3. 90 - 4. 43,p < 0. 01), 足底腱膜付着部の厚さは,2. 69 mm(95% CI 2. 46 - 2. 92,p < 0. 01)だった.結論:本調査結果は目安の 1 つとし て有用であるが,日常生活の活動性,体格,疾患,X線靭帯骨棘など腱肥厚に影響を及ぼす因子を考慮し,日本人 における正常値を検討する必要がある. The normal thicknesses of entheseal insertions in the lower limbs of Japanese individuals Kenta KAMO1, Seigo NISHINO2, Yuko MATSUDA2, Asako KAWASHIMA2, Tomoko YOSHIMOTO2 Abstract Purpose : Ultrasound examination of enthesitis is used to diagnose spondyloarthritis(SpA)early and to evaluate SpA activity. We used the Glasgow ultrasound enthesitis scoring system(GUESS)to screen and evaluate SpA. GUESS defines the cut-off values for the thicknesses of entheseal insertions. However, the thicknesses of entheseal insertions among Japanese individuals is not known. We aimed to clarify the normal thicknesses of entheseal insertions in the lower limbs of Japanese individuals. Subjects and Methods : We evaluated subclinical sites in 77 individuals(770 sites)to screen for SpA and excluded persons with radiographic evidence of enthesophytes, inflammatory bowel disease, psoriasis, and collagen diseases such as SpA and rheumatoid arthritis. Results and Discussion : We evaluated 41 insertions of the quadriceps muscle, 58 insertions of the proximal patellar tendon, 53 insertions of the distal patellar tendon, 24 insertions of the Achilles tendon, and 39 plantar fascia. The mean thickness of quadriceps muscle insertions was 5. 11 mm(95% confidence interval[CI], 4. 88 – 5. 34, p < 0. 01). The mean thickness of proximal patellar tendon insertions was 3. 25 mm(95% CI, 3. 08 – 3. 43, p < 0. 01). The mean thickness of distal patellar tendon insertions was 3. 84 mm(95% CI, 3. 64 – 4. 05, p < 0. 01). The mean thickness of Achilles tendon insertions was 4. 16 mm(95% CI, 3. 90 – 4. 43, p < 0. 01). The mean thickness of the plantar fascia was 2. 69 mm(95% CI, 2. 46 – 2. 92, p < 0. 01). Conclusion : Our results provide a useful guide for the average thicknesses of entheseal insertions among Japanese individuals. The normal thicknesses should be validated in a larger Japanese cohort to consider factors such as activities of daily living, body shape, participation in sports, sex, radiographic evidence of enthesophytes, and disease. Keywords enthesitis, spondyloarthritis, entheseal insertions, ultrasound, early arthritis 山口赤十字病院整形外科,2同検査部 Department of Orthopedics Surgery, 2Department of Clinical Examinations, Yamaguchi Red Cross Hospital, 53︲1 Yahatababa, Yamaguchi 753︲8519, Japan Received on July 2, 2015; Revision accepted on August 13, 2015 J-STAGE. Advanced published. date: October 26, 2015 1 1 Jpn J Med Ultrasonics
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