No. 11 http://nucleosome.kyushu-u.ac.jp News Letter 1. 2. 2015 5th Jan : : PLOS One Nature 3. 4. : 1. lncRNA lncRNA hnRNP U X hnRNP U hnRNP U Xist RNA Xist RNA lncRNA cre hnRNP U Xist RNA X X hnRNP U lncRNA hnRNP U hnRNP U lncRNA 50% Neutrophil Extracellular Traps 2004 NETs 3 4 Brinkmann Zychlinsky NETs HL-60 NETs NETs DNA DNA HPLC UV UV (Sci.Rep.,4:4950|2014 ) HPLC 2. PLOS One DNA binding properties of the actin-related protein Arp8 and its role in DNA repair. Osakabe A, Takahashi Y, Murakami H, Otawa K, Tachiwana H, Oma Y, Nishijima H, Shibahara KI, Kurumizaka H, Harata M. Published: October 09, 2014 http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0108354 DNA DNA DNA DNA DNA ATP DNA DNA INO80 Actin-related-protein: Arp Arp8 DNA Arp8 15 DNA INO80 DNA Arp8 DNA Arp8 DNA Arp8 DNA DNA Arp8 ATP DNA Arp8 ATP DNA Arp8 ATP DNA ATP Arp8 Arp8 Nalm-6 B Arp8 DNA DNA Arp8 DNA INO80 DNA DNA INO80 DNA INO80 Arp8 DNA INO80 Nature ONLINE Nature Reviews Molecular Cell Biology Regulation of RNA polymerase II activation by histone acetylation in single living cells Stasevich TJ, Hayashi-Takanaka Y, Sato Y, Maehara K, Ohkawa Y, Sakata-Sogawa K, Tokunaga M, Nagase T, Nozaki N, McNally JG, Kimura H. Nature. 2014 Dec 11;516(7530):272-275 http://www.nature.com/nature/journal/v516/n7530/full/nature13714.html RNA II RNAP2 Fab-based live endogenous modification labeling; FabLEM RNAP2 H3 27 H3K27ac RNAP2 H3K27ac ChIP-seq H3K27ac RNAP2 3. SWR1 and INO80 Chromatin Remodelers Contribute to DNA Double-Strand Break Perinuclear Anchorage Site Choice. Chihiro Horigome, Yukako Oma, Tatsunori Konishi, Roger Schmid, Isabella Marcomini, Michael Hauer, Vincent Dion, Masahiko Harata and Susan M. Gasser Mol Cell. 2014 Aug 21;55(4):626-39 DNA DNA DNA double strand break: DSB DSB (Dion et al. 2012, Nat Cell Biol; Mine-Hattab and Rothstein 2012, Nat Cell Biol; Seeber et al. 2013, Genes Dev) DSB Nup84 SUN Mps3 (Nagai et al. 2008, Science; Oza et al. 2009, Gens Dev; Kalocsay et al. 2009 Mol Cell; Oza et al. 2010, Cell Cycle) DSB DSB SWR1 INO80 DSB Mps3 Htz1 DSB Mps3 DSB Mps3 SUMO DSB Mps3 Rad51 Mps3 INO80 G1 SWR1 uSCR DSB Slx5/Slx8 SUMO FMI HO 150 2014 CCD nucleolus organizer region: NOR DNA 4. DNA http://nucleosome.kyushu-u.ac.jp/outreach/20150112.html 2015 1 12 ( ) 13:00 17:30 ( 12:30) 1 DNA DNA DNA 2 DNA 3 DNA DNA 130 X Chromatin Structure, Dynamics, and Function http://www.knt-ec.net/2015/iscsdf/ http://nucleosome.kyushu-u.ac.jp/activities/20150823.html 2015 8 23-26 Invited speakers: Frederic Berger (GMI, Austria) Kerstin Bystricky (Univ. Toulouse, France) Philippe Collas (Univ. Oslo, Norway) Roland Foisner (MFPL, Austria) Peter Fraser (Babraham Inst., UK) Martin W. Hetzer (Salk Inst., USA) Anthony Imbalzano (Univ. Mass, USA) Joachim Lingner (EPFL, Switzerland) Michael Guy Poirier (Ohio State Univ., USA) Kannanganattu V. Prasanth (Univ. Illinois, USA) Maria-Elena Torres-Padilla (IGBMC, France) Paul A. Wade (NIEHS, NIH, USA 編集後記：寒さが身に沁みる今日この頃ですが、いかがお過ごしでしょうか。私は年末年始も容赦なく宿題がてんこ盛りの中、いつの 間にか年が明けていて焦りました。みなさま風邪などひかれないよう、ご自愛ください。今年もどうぞよろしくお願いします。 HiKi 間違い探し 左右の絵で違うところはどこでしょう？ 答えは本研究領域のホームページで！ http://nucleosome.kyushu-u.ac.jp/index.html
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