Surname(s) Massimo Gentile Address(es) Department of Molecular

Europass
Curriculum Vitae
Personal information
First name(s) / Surname(s)
Address(es)
Massimo Gentile
Department of Molecular Medicine, Laboratory of Virology, Viale di Porta Tiburtina 28, 00185 Rome
Telephone(s)
0039-06-44741224
Fax(es)
0039-06-44741236
E-mail
Nationality
Date of birth
Gender
Occupational field
Mobile:
[email protected]
Italian
March - 4 -1959
male
Virology
Work experience
1985-1986
1991-1992
1992
1994, 1995, 1996
1998
Occupation or position held
Main activities and responsibilities
Postgraduate in Virology, Institute of Virology, “Sapienza” University of Rome.
Postdoctoral Research Fellow, Dept. of Virology, Robert Koch-Institut, Electron Microscopy Unit, Prof.
H. Gelderblom, Berlin, Germany
Visiting Scientist, Dept. of Biochemistry, Biomedical Center, Electron Microscopy Unit, Dr. S. Hoglund,
Uppsala University, Sweden.
Visiting Scientist, Dept of Virology, Robert Koch-Institut, Electron Microscopy Unit, Prof H. Gelderblom,
Berlin, Germany.
Visiting Scientist, Karoliska Institutet, Dept. of Immunology, Microbiology, Patology and Infectious
Diseases. Division of Clinical Virology, Prof. A. Vahlne, Huddinge University Hospital, Stockholm,
Sweden
Assistant Professor
- Fine structure, antigenic make-up and cell interactions of human and animal viruses, with particular
emphasis on Retrovirus, HIV and Herpesvirus.
- Diagnostic electron microscopy in Virology
- Diagnosis of infectious diseases by serologic and molecular tests
- Responsible for under/ postgraduate teaching/supervision and research in Medical Virology
Name and address of employer
Sector
“Sapienza” University of Rome, Viale di Porta Tiburtina 28, 00185 Rome
Medical Microbiology
Education and training
Page 1/5 - Curriculum vitae of
Surname(s) First name(s)
For more information on Europass go to http://europass.cedefop.europa.eu
© European Union, 2004-2010 24082010
1983
2002
1992
1994
Degree in Pharmacy, “Sapienza” University of Rome
Postgraduate MD specializzation course in Microbiology and Virology, “Sapienza” University of Rome
Postdoctoral Fellows: sponsored by Italian Ministry of Health against AIDS infection.
Postdoctoral Fellows: sponsored by “Deutsher Akademisher Austausschdienst e.V.” of German
Government (DAAD).
1994
EMBO course in "Low temperature immunocy citochemistry and quantitation in biological electron
microscopy. 14-20 May, , Oslo, Norwey
LEICA course on “ Cryofixation, Freeze-Substitution and Freeze-Drying: Important methods for
research in Biology and Medicine”. Rome, December 3,.
1996
Name and type of organisation
providing education and training
Personal skills and competences
Mother tongue(s)
Other language(s)
Self-assessment
European level (*)
Language
Language
“Sapienza” University of Rome; Dept of Virology, Robert Koch-Institut, Berlin, Germany
Techniques and diagnosis of viruses in electron microscopy
Italian
(1) English, (2) German
Understanding
Speaking
Writing
Listening
Reading
Spoken
interaction
Spoken
production
1 B1
1 B1
1 B1
1 B1
1 B1
2 A1
2 A1
2 A1
2 A1
2 A1
(*) Common European Framework of Reference for Languages
Additional information
Reviewer for following journals:
-European Journal of Clinical Microbiology & Infectious Diseases;
-International Journal of Infectious Diseases
Receiving
Annexes
Page 2/5 - Curriculum vitae of
Surname(s) First name(s)
List any items attached.
For more information on Europass go to http://europass.cedefop.europa.eu
© European Union, 2004-2010 24082010
Scientific Publication
1) V. Ruggiero, G. Antonelli, G. Conciatori, M. Gentile, J. Van Damme and F. Dianzani."The in vitro
antiviral activity of Tumor Necrosis Factor (TNF) in WISH cells is mediated by IFN-beta induction"
(1989) Antiviral Resarch, 11, 77-88, I.F. 2.758
2) V. Ruggiero, G. Antonelli, M. Gentile, G. Conciatori and F. Dianzani. "Comparative study of the
antiviral activity of TNF-alpha, Lymphotoxin/TNF-beta and IL-1 in WISH cells" (1989) Immunology
letters, 21, 165-170, I.F. 1.546
3) F. Dianzani, F. De Marco, P. Di Marco, M. Gentile, G. Antonelli, P. Amicucci, A. Cefaro, V.
Ruggiero, O. Turriziani e M.R. Capobianchi. "Produzione di IFN-alfa acido-labile da PBMC stimolati
con cellule infette da HIV" (1989) Annali Istituto di Igiene, May-Aug., 1(3-4), 647-60,
4) P. Amicucci, O. Turriziani, M. Gentile, E. Riva, A. Faggioni, M.R. Torrisi, M.R. Capobianchi, G.
Antonelli, F. Dianzani. "Cinetica di replicazione dell'HIV su C8166: aspetti biologici e applicativi" (1990)
L'igiene moderna, Vol. 94, 717-730,
5) M.R. Capobianchi, P. Mattana, M. Gentile, G.C. Conciatori, H. Hankel, F. Dianzani. "Role of
glycosilation in the susceptibility of acid-labile interferon alpha to acid treatment" (1991) J. Biol. Regul.
Homeost. Agents, Vol. 5, No 4, 147-153, I.F. 0.853
6) C.M. Ausiello, G. Antonelli, G.C. Spagnoli, M. Gentile, F. Urbani, M. Gitto. "A macrophage derived
blastogenic factor- MBF-induces cytokines and cytotoxic effectors in human peripheral blood
mononuclear cells" (1992) J. Biol. Regul. Homeost. Agents, Vol. 6, No 1, 8-14, I.F. 0.803
7) M.R. Capobianchi, S. Fais, C. Castilletti, M. Gentile, F. Ameglio and F. Dianzani. " A simple and
reliable method to detect cell membrane proteins on infectious human immunodeficiency virus-1
particles" (1994) J. Infect. Dis., 169, 886-889, I.F. 4.988
8) M. Gentile, T. Adrian, A. Scheidler, M. Ewald-Feldt, F. Dianzani, G. Pauli and H. Gelderblom.
"Determination of the size of HIV using Adenovirus type 2 as an internal length marker" (1994) J.Virol.
Meth., 48, 43-52, I.F. 1.505
9) S. Fais, M.R. Capobianchi, I. Abbate, C. Castilletti, M. Gentile, P. Cordiali Fei, F. Ameglio, F.
Dianzani. "Unidirectional budding of HIV-1 at the site of cell to cell contact is associated with copolarization of intercellular adhesion molecules (ICAM)-1 and HIV-1 viral matrix protein. (1995) AIDS,
9, 329-335, I.F. 8.018
10) B. Ludewig, J. Holzmeister, M. Gentile, H.R. Gelderblom, K. Rokos, Y. Becker and G. Pauli.
"Replication pattern of human immunodeficiency virus type 1 in mature Langerhans cells. (1995) J.
Gen. Virology, 76, 1317-1325, I.F. 3.126
11) F. Dianzani, O. Scheglovitova, M. Gentile, V. Scanio, C. Barresi, B. Ficociello, F. Bianchi, D.
Fiumara, M.R. Capobianchi. “Interferon gamma stimulates cell mediated transmission of HIV-1 from
abortively infected endothelial cells. (1996) AIDS Res. and Hum. Retrovirus, Vol. 12, Num. 7, 621-627,
I.F. 2.870
12) C. Rozera, S. Baccarini, M. Gentile, M.R. Torrisi, E. Proietti, M. Federico and S. Pulciani. “Stable
transfection of HIV provirus into a murine packaging cell line”. (1997) Acta Virologica, 41, 105-110,
I.F. 0.558
13) F. Dianzani, C. Castilletti, M. Gentile, H.R. Gelderblom, F. Frezza, M.R. Capobianchi. “Effects of
IFN-alpha on late stages of HIV-1 replication cycle” (1998) Biochimie, Vol. 80, No 8-9, 745-754, I.F.
2.324
14) G. Cardinali, M. Gentile, M. Cirone, C. Zompetta, L. Frati, A. Faggioni, and M.R. Torrisi. “Viral
glycoproteins accumulate in newly formed Annulate Lamellae following infection of lymphoid cells by
Human Herpesvirus 6” (1998) J. Virology, Vol. 72, No 12, 9738-9746, I.F. 5.930
15) M.R. Torrisi, M. Gentile, G. Cardinali, M. Cirone, C. Zompetta, L.V. Lotti, L. Frati and A. Faggioni.
“Intracellular Transport and Maturation Pathway of Human Herpesvirus 6” (1999) Virology, 257, 460471, I.F. 3.507
Page 3/5 - Curriculum vitae of
Surname(s) First name(s)
16) S. Uccini, E. Riva, G. Antonelli, G. D’Offizi, A. Prozzo, A. Angelici, A. Faggioni, A. Angeloni, M.R.
Torrisi, M. Gentile, L.P. Ruco, C.D. Baroni. “The benign cystic lymphoepithelial lesion of the parotid
gland
is a viral reservoir in HIV type-1 infected patients” (1999) AIDS Res. Hum. Retrovirus, Vol 15
For more information on Europass go to http://europass.cedefop.europa.eu
1339-1344,
2.870 24082010
©
European Union,I.F.
2004-2010
17) G. Andreola, L. Rivoltini, C. Castelli, V. Huber, P. Perego, P.Deho, P. Squarcina, P. Accornero, F.
Luzupone, L. Luigini, A. Stringaro, A. Molinari, G. Arancia, M. Gentile, G. Permiani and S. Fais.
“Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles” (2002) J.
Exp. Medicine, Vol. 195, N° 10, May 20, 1303-1316,
I.F. 15.837
18) O. Turriziani, C. Scagnolari, F. Bambacioni, F. Bellomi, F. Focher, M. Gentile and G. Antonelli.
“Selection of a T-cell line resistant to stavudine and zidovudine by prolonged treatment with stavudine”
(2002) Antiviral Therapy, 7, 105-111, I.F. 6.565
19) M. Caruso, M. Cavaldesi, M. Gentile, O. Sthandier, P. Amati and M.I. Garcia. “Role of sialic acidcontaining molecules and the alpha-4-beta-1 integrin receptor in the early steps of polyomavirus
infection”. (2003).J. Gen. Virology, 84, 2927-2936, I.F. 3.026
20) Gentile M., H.R. Gelderblom (2005). Rapid viral diagnosis: role of electron microscopy. New
Microbiologica, vol. 28; p. 1-12, I.F. 0.529
21) V.Huber, S. Fais, M. Iero, L. Lugini, P. Canese, P. Squarcina, A. Zaccheddu, M.Colone, G.
Arancia, Gentile M., E. Seregni, R. Valenti, G. Ballabio, F.Belli, E. Leo, G. Parmiani, L. Rivoltini (2005).
Human colorectal cancer cells induce T cell death through release of pro-apoptotic microvesicles: Role
in immune escape. Gastroenterology, vol. 128 (7); p. 1796-1804; I.F. 12.386
22) Molinari A., Stringaro A., Gentile M., Colone M., Toccacieli L., Arancia G. (2005). Invasive
properties of multidrug resistant human melanomacells. Ital. J. Anat. And Embriol,, vol. 110 (Suppl. 1);
p. 135-141,
23) L. Lugini, P. Materrese, A. Tinari, F. Lozupone, C. Federici, E. Iessi, Gentile M., F. Luciani, G.
Parmiani, L. Rivoltini, W. Malorni and S. Fais. (2006). Cannibalism of Live Lymphocytes by Human
Metastatic but Not Primary Melanoma Cells. Cancer Research, vol. 66 (7); p. 3629-3638, I.F. 7.656
24) Caruso M, Busanello A, Sthandier O, Cavaldesi M, Gentile M., Garcia M.I. and Amati P (2007).
Muatation in the VP1-LDV motif of the murinepolyomavirus affects viral infectivity and conditions virus
tissue tropism in vivo. J. Molec. Biol., vol. 367; p. 54-64, I.F. 4.472
25) Pierangeli A, Gentile M., Di Marco P, PagnottiP, Scagnolari C, Trombetti S, Lo Russo L, Tromba
V, MorettiI C, Midulla F. and Antonelli A (2007). Detection and typing by molecular techniques of
respiratory viruses in children hospitalized for acute respiratory infection in Rome, Italy. Journal of
Medical Virology, vol. 79; p. 463-468, I.F. 2.831
26) Caviglia R, Ribolsi M, Gentile M., Rabitti C, Emerenziani S, Guarino P.L, Petitti T. and Cicala M
(2007). Dilated intercellular spaces and acid reflux at the distal and proximal oesophagus in non
erosive gastro-oesophagus reflux disease (NERD) patients. Alimentary Pharmacology & Therapeutics,
vol. 25; p. 629-636; I.F. 3.201
27) Colone M, Calcabrini A, Toccacieli L, Bozzuto G, Stringaro A, Gentile M., Cianfriglia M, Ciervo A,
Caraglia M, Budillon A, Meo G, Arancia G, Molinari A (2008). The multidrug Transporter PGlycoprotein: A Mediator of Melanoma Invasion?. Journal of Investigate Dermatology, vol. 128 (4); p.
957-971, I.F. 5.251
28) Ribolsi M, Perrone G, Caviglia R, Gentile M., Emerenziani S, Luca Guarino M.P, Petitti T, Cicala
M (2009). Intercellular space diameters of the oesophageal epithelium in NERD patients: head to head
comparision between light and electron microscopy. Digestive and Liver Disease, vol. 41 (1); p. 9-14,
ISSN: 1590-8658; I.F. 2.577
29) Gentile M., Galli C, Pagnotti P, Di Marco P, Tzantzoglou S, Bellomi F, Ferreri M.L, Selvaggi C,
Antonelli G (2009). Measurement of the sensitivity of different commercial assays in the diagnosis of
CMV infection in pregnancy. European Journal of Clinical Microbiology & Infectious Disease, I.F.
2.866
30) Pierangeli A., Scagnolari C., Gentile M., Spina M.T., Iudicello A., Bertazzoni G. Antonelli G. (2009)
“Virological diagnosis of respiratory virus infection in patients attending an emergency department
during the influenza season”. Clin. Microbiol. Infect. (2010), 16, (4), 391-393 I.F. 3.554
Page 4/5 - Curriculum vitae of
Surname(s) First name(s)
For more information on Europass go to http://europass.cedefop.europa.eu
© European Union, 2004-2010 24082010
Textbooks (Chapters, etc.)
Page 5/5 - Curriculum vitae of
Surname(s) First name(s)
2008 Principi di Virologia Medica. G. Antonelli, M.Clementi. Casa Editrice Ambrosiana. Prima
edizione
For more information on Europass go to http://europass.cedefop.europa.eu
© European Union, 2004-2010 24082010

Download Report