Università degli Studi di Torino Forum Bone and Mineral Research Board members: Alberta Zallone (president) Patrizia D’Amelio Luigi Gennari Fernando Gianfrancesco Luca Pietrogrande FORUM IN BONE Secretary Marco Di Stefano INFORMATION Participation Participation is reserved to members of the Forum in Bone and Mineral Research, who must registrate for the meeting. CME (Continuing medical education) The event has been included in the program of Continuing Medical Education for the profession: medical doctor and surgeon, interdisciplinary profession and biologist ID CME 173-114832 Credits: 8 FORUM IN BONE SPONSOR Thank you for the unrestricted grant CME Provider University of Turin - Agenas Provider n. 173 Corso Dogliotti, 38 - 10126 Turin Tel. +39 011 6705315 • [email protected] CME scientific coordinators: Simone Cenci, Patrizia D’Amelio Forum Congress Venue Accademia di Medicina via Po 18 - Torino Organizing secretariat Via Gozzano 14 - 10073 Ciriè, Turin Infoline 0119211467 - Fax 011 9224992 [email protected] • www.symposium.it AND MINERAL RESEARCH 15TH Meeting AND MINERAL RESEARCH 15TH Meeting SPA - Società Prodotti Antibiotici S.p.A. Torino, March 6-7, 2015 Printed on FSC paper (Forest Stewardship Council) Meeting scientific organizers: Simone Cenci - Carmine Settembre Aula Magna Accademia di Medicina via Po 18 - Torino FORUM IN BONE AND MINERAL RESEARCH 15TH Meeting SCIENTIFIC PROGRAM Friday, March 6 2015 14.30 Welcome and introductory remarks. G. C. Isaia, Torino - A. Zallone, Bari 14.40 Lecture: From monogenic to complex diseases. A. Falchetti, Bologna COMMUNICATIONS: Electrolyte metabolism and kidney disorders Chairpersons: F. Gianfrancesco, Napoli D. Rendina, Napoli 15.10 Epistatic interaction of VDR and SLC13A2 genes in the pathogenesis of hypocitraturia in patients with calcium oxalate recurrent nephrolithiasis. R. Muscariello, Napoli 15.25 Claudin - 14 gene polymorphisms regulate urinary calcium excretion. T. Arcidiacono, Milano 15.40 Abdominal aortic calcification measured by dexa predicts cardiovascular risk in patients with chronic kidney disease. L. Macrina, Milano Higher - order metabolism Chairman: C. Settembre, Napoli 15.55 Topic and speaker introduction. C. Settembre, Napoli 16.00 Regulation of bone mass by a novel gut-liver-bone axis. V. K. Yadav, Hinxton, Cambridge (U. K.) 16.30 Regulation of the central nervous system by osteocalcin and its potential link with ageassociated cognitive decline. F. Oury, Paris (France) 17.00 Coffee break COMMUNICATIONS: Energy metabolism and bone quality Chairpersons: A. Del Fattore, Roma - D. Merlotti, Siena 17.20 Physical activity can significantly improve osteoblast homeostasis alterations induced by serum of obese subjects: in vitro characterization. V. Papa, Roma 17.35 Effect of type 2 diabetes on bone cell precursors. I. Buondonno, Torino 17.50 Low trabecular bone score and lower bone mineral density at femoral neck are associated with asymptomatic vertebral fractures in wellcompensated type 2 diabetic patients. V. Zhokouskaya, Milano 18.05 Assessment of microtrabecular bone structure by DXA (Trabecular Bone Score, TBS). M. Di Stefano, Torino Diabetes and bone Chairpersons: L. Gennari, Siena - N. Napoli, Roma 18.20 Diabetes and bone: from pathophysiology to fracture risk assessment. N. Napoli, Roma 18.45 Reciprocal interaction between bone and glucose homeostasis: implications for treatment. L. Gennari, Siena 19.10 General Assembly Saturday, March 7 2015 10.00 Intronic mutations in the TCIRG1 gene cause human autosomal recessive osteopetrosis. E. Palagano, Milano 10.15 Antiretroviral treatment and bone: age-dependent effects of Tenofovir on zebrafish skeleton. M. Carnovali, Milano 10.30 Intrauterine growth restriction, gestational age, steroidal prophylaxis and breast feeding influence bone mass in prepubertal children. N. Di Iorgi, Genova 10.45 SuPAR: a new biomarker of prosthetic joint infection. E. Galliera, Milano 11.00 Coffee break COMMUNICATIONS: Translational Chairpersons: B. Peruzzi, Roma - I. Roato, Torino 11.15 In vivo and in vitro evidence for enhanced immunoglobulin production in Paget’s disease of bone with P62/SQSTM1 mutation. D. Merlotti, Siena 11.30 P62 addiction of multiple myeloma: exploiting autophagy to overcome Bortezomib resistance. T. Perini, Milano 11.45 Role of irisin in bone remodeling: in vitro and in vivo studies. C. Cuscito, Bari Opening Lecture Chairman: C. Scotti, Milano 9.00 Osteogenic and vasculogenic grafts engineered from adipose derived cells: a translational process. I. Martin, Basel (Switzerland) COMMUNICATIONS: Miscellaneous Chairpersons: G. Colaianni, Bari - C. Sobacchi, Milano 12.15 Engineering normal and pathologic bone. C. Scotti, Milano 9.45 A large novel CDC73 gene deletion found in cis with a single-nucleotide 5’UTR variant: cotransmission in a 3-generation Canadian family with familial hyperparathyroidism and parathyroid carcinoma. V. Guarnieri, San Giovanni Rotondo 12.00 The role of light in bone remodeling. I. Gigante, Bari Closing seminar Chairman: I. Martin, Basel (Switzerland) 12.45 Closing remarks. A. Zallone, Bari
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