FORUM IN BONE AND MINERAL RESEARCH 15TH Meeting SCIENTIFIC PROGRAM

Università degli Studi di Torino
Forum Bone and Mineral Research
Board members:
Alberta Zallone (president)
Patrizia D’Amelio
Luigi Gennari
Fernando Gianfrancesco
Luca Pietrogrande
FORUM IN
BONE
Secretary
Marco Di Stefano
INFORMATION
Participation
Participation is reserved to members of the Forum in
Bone and Mineral Research, who must registrate for the
meeting.
CME (Continuing medical education)
The event has been included in the program of Continuing
Medical Education for the profession: medical doctor and
surgeon, interdisciplinary profession and biologist
ID CME 173-114832 Credits: 8
FORUM IN
BONE
SPONSOR
Thank you for the unrestricted grant
CME Provider
University of Turin - Agenas Provider n. 173
Corso Dogliotti, 38 - 10126 Turin
Tel. +39 011 6705315 • [email protected]
CME scientific coordinators:
Simone Cenci, Patrizia D’Amelio
Forum Congress Venue
Accademia di Medicina
via Po 18 - Torino
Organizing secretariat
Via Gozzano 14 - 10073 Ciriè, Turin
Infoline 0119211467 - Fax 011 9224992
[email protected] • www.symposium.it
AND
MINERAL
RESEARCH
15TH Meeting
AND
MINERAL
RESEARCH
15TH Meeting
SPA - Società Prodotti Antibiotici S.p.A.
Torino,
March 6-7, 2015
Printed on FSC paper (Forest Stewardship Council)
Meeting scientific organizers:
Simone Cenci - Carmine Settembre
Aula Magna Accademia di Medicina
via Po 18 - Torino
FORUM IN BONE AND MINERAL RESEARCH
15TH Meeting
SCIENTIFIC PROGRAM
Friday, March 6 2015
14.30 Welcome and introductory remarks.
G. C. Isaia, Torino - A. Zallone, Bari
14.40 Lecture: From monogenic to complex diseases.
A. Falchetti, Bologna
COMMUNICATIONS:
Electrolyte metabolism and kidney disorders
Chairpersons: F. Gianfrancesco, Napoli
D. Rendina, Napoli
15.10 Epistatic interaction of VDR and SLC13A2 genes in
the pathogenesis of hypocitraturia in patients with
calcium oxalate recurrent nephrolithiasis.
R. Muscariello, Napoli
15.25 Claudin - 14 gene polymorphisms regulate urinary
calcium excretion.
T. Arcidiacono, Milano
15.40 Abdominal aortic calcification measured by dexa
predicts cardiovascular risk in patients with chronic
kidney disease.
L. Macrina, Milano
Higher - order metabolism
Chairman: C. Settembre, Napoli
15.55 Topic and speaker introduction.
C. Settembre, Napoli
16.00 Regulation of bone mass by a novel gut-liver-bone axis.
V. K. Yadav, Hinxton, Cambridge (U. K.)
16.30 Regulation of the central nervous system by
osteocalcin and its potential link with ageassociated cognitive decline.
F. Oury, Paris (France)
17.00 Coffee break
COMMUNICATIONS:
Energy metabolism and bone quality
Chairpersons: A. Del Fattore, Roma - D. Merlotti, Siena
17.20 Physical activity can significantly improve osteoblast
homeostasis alterations induced by serum of obese
subjects: in vitro characterization.
V. Papa, Roma
17.35 Effect of type 2 diabetes on bone cell precursors.
I. Buondonno, Torino
17.50 Low trabecular bone score and lower bone
mineral density at femoral neck are associated
with asymptomatic vertebral fractures in wellcompensated type 2 diabetic patients.
V. Zhokouskaya, Milano
18.05 Assessment of microtrabecular bone structure by
DXA (Trabecular Bone Score, TBS).
M. Di Stefano, Torino
Diabetes and bone
Chairpersons: L. Gennari, Siena - N. Napoli, Roma
18.20 Diabetes and bone: from pathophysiology to fracture
risk assessment.
N. Napoli, Roma
18.45 Reciprocal interaction between bone and glucose
homeostasis: implications for treatment.
L. Gennari, Siena
19.10 General Assembly
Saturday, March 7 2015
10.00 Intronic mutations in the TCIRG1 gene cause human
autosomal recessive osteopetrosis.
E. Palagano, Milano
10.15 Antiretroviral treatment and bone: age-dependent
effects of Tenofovir on zebrafish skeleton.
M. Carnovali, Milano
10.30 Intrauterine growth restriction, gestational age,
steroidal prophylaxis and breast feeding influence
bone mass in prepubertal children.
N. Di Iorgi, Genova
10.45 SuPAR: a new biomarker of prosthetic joint infection.
E. Galliera, Milano
11.00 Coffee break
COMMUNICATIONS: Translational
Chairpersons: B. Peruzzi, Roma - I. Roato, Torino
11.15 In vivo and in vitro evidence for enhanced
immunoglobulin production in Paget’s disease of
bone with P62/SQSTM1 mutation.
D. Merlotti, Siena
11.30 P62 addiction of multiple myeloma: exploiting
autophagy to overcome Bortezomib resistance.
T. Perini, Milano
11.45 Role of irisin in bone remodeling: in vitro and in
vivo studies.
C. Cuscito, Bari
Opening Lecture
Chairman: C. Scotti, Milano
9.00 Osteogenic and vasculogenic grafts engineered from
adipose derived cells: a translational process.
I. Martin, Basel (Switzerland)
COMMUNICATIONS: Miscellaneous
Chairpersons: G. Colaianni, Bari - C. Sobacchi, Milano
12.15 Engineering normal and pathologic bone.
C. Scotti, Milano
9.45
A large novel CDC73 gene deletion found in cis with
a single-nucleotide 5’UTR variant: cotransmission
in a 3-generation Canadian family with familial
hyperparathyroidism and parathyroid carcinoma.
V. Guarnieri, San Giovanni Rotondo
12.00 The role of light in bone remodeling.
I. Gigante, Bari
Closing seminar
Chairman: I. Martin, Basel (Switzerland)
12.45 Closing remarks.
A. Zallone, Bari