Magnetic Resonance Techniques in Multiple

Università Vita-Salute
San Raffaele
Neuroimaging Research Unit
Institute of Experimental Neurology, Division of Neuroscience,
San Raffaele Scientific Institute and Vita - Salute San Raffaele University
Magnetic Resonance Techniques
in Multiple Sclerosis
Eighteenth Advanced Course
SCIENTIFIC PROGRAM
CME ACCREDITED COURSE
Milan, 19-20 March 2015
San Raffaele Scientific Institute
Via Olgettina, 60 - 20132 Milano, Italy
ORGANIZING SECRETARIAT
Biomedia srl – Monica Arosio
Via L. Temolo 4 – 20126 Milano
Tel. 02/45498282 - Fax 02/45498199
e-mail: [email protected]
Biomedia utilizza un Sistema di Gestione Qualità Certificato per
progettazione ed erogazione di eventi di formazione
residenziale e a distanza e di servizi organizzativi per corsi e convegni
MAGNETIC RESONANCE TECHNIQUES
IN MULTIPLE SCLEROSIS
Eighteenth Advanced Course
Milan, 19-20 March 2015
SCIENTIFIC DIRECTION:
M. Filippi
G. Comi
SCIENTIFIC SECRETARIAT:
M.A. Rocca
ORGANIZING SECRETARIAT:
G. Nyitrai
L. Zonca
FACULTY MEMBERS
Maria P. Amato (Firenze, Italy)
Massimo Filippi (Milan, Italy)
John Ashburner (London, UK)
Jeroen J. Geurts (Amsterdam, Netherlands)
Marco Battaglini (Siena, Italy)
Roland Henry (San Francisco, USA)
Ralph Benedict (Buffalo, USA)
Mark A. Horsfield (Leicester, UK)
Giancarlo Comi (Milan, Italy)
Mark Jenkinson (Oxford, UK)
John De Luca (West Orange, USA)
Carsten Lukas (Bochum, Germany)
Nicola De Stefano (Siena, Italy)
Maria A. Rocca (Milan, Italy)
Christian Enzinger (Graz, Austria)
James Sumowski (West Orange, USA)
Arman Eshaghi (Teheran, Iran)
Koen Van Leemput (Boston, USA)
Monica Falautano (Milan, Italy)
Alex P. Zijdenbos (Montreal, Canada)
Magnetic Resonance Techniques in Multiple Sclerosis - Eighteenth Advanced Course
Milan, 19-20 March 2015
1
Programme
19 March 2015
09.00-09.15
Welcome, introductory remarks
G. Comi
09.15-09.30
Program overview
M. Filippi
Atrophy quantification in MS: from clinical needs to methodological
pitfalls. Towards the identification of the best method?
SESSION I - THE CLINICAL PERSPECTIVE
Chairs: M. Filippi, G. Comi
09.30-10.00
What structures should be measured?
Whole brain vs WM/GM segmentation?
N. De Stefano
10.00-10.30
Deep GM nuclei: a simple, clinically meaningful measure?
R. Benedict
10.30-11.00
Spinal cord atrophy: the missing measure?
C. Lukas
11.00-11.30
Coffee break
SESSION II - METHODOLOGICAL CONSIDERATIONS
Chairs: N. De Stefano, R. Henry
2
11.30-12.00
How to measure: accuracy, reproducibility, sensitivity to changes
M.A. Horsfield
12.00-12.30
T1 lesion refilling: how and why?
M. Battaglini
12.30-13.30
Lunch
Magnetic Resonance Techniques in Multiple Sclerosis - Eighteenth Advanced Course
Milan, 19-20 March 2015
Programme
SESSION III - METHODS AND SOFTWARES: CROSS-SECTIONAL AND
LONGITUDINAL APPLICATIONS, PROS AND CONS I
Chairs: M.A. Rocca, A. Eshaghi
13.30-14.00
FSL: SIENA, SIENAx, FIRST
M. Jenkinson
14.00-14.30
SPM
J. Ashburner
14.30-15.00
Freesurfer
K.V. Leemput
15.00-15.30
Afternoon tea
SESSION IV - METHODS AND SOFTWARES: CROSS-SECTIONAL AND
LONGITUDINAL APPLICATIONS, PROS AND CONS II
Chairs: R. Benedict, M.A. Horsfield
15.30-16.00
CIVET
A.P. Zijdenbos
16.00-16.30
ANTs
A. Eshaghi
16.30-17.00
How to choose a method and its implementation
R. Henry
17.00-18.00
SESSION V - ROUND TABLE SUMMING UP AND CONCLUSIONS
Chair: M. Filippi
Discussants: N. De Stefano, R. Benedict, C. Lukas,
M.A. Horsfield, R. Henry
Magnetic Resonance Techniques in Multiple Sclerosis - Eighteenth Advanced Course
Milan, 19-20 March 2015
3
Programme
20 March 2015
Imaging cognitive dysfunction in MS
SESSION VI - THE CLINICAL PERSPECTIVE
Chairs: M. Falautano, J. Sumowski
9.00-9.15
Introduction
G. Comi
9.15-9.45
Neuropsychological profiles in MS: from cognitive relapse to dementia
J. De Luca
9.45-10.15
Cognitive assessment: towards a unified evaluation
M.P. Amato
10.15-10.45
Coffee break
SESSION VII - THE IMAGING PERSPECTIVE
Chairs: J. De Luca, M.P. Amato
4
10.45-11.15
WM lesions and damage: just a disconnection syndrome?
C. Enzinger
11.15-11.45
GM lesions and damage: do they explain the whole story?
J.J. Geurts
11.45-12.15
Plasticity: what is the evidence?
M.A. Rocca
12.15-12.45
Brain reserve and cognitive reserve: where are we going?
J. Sumowski
12.45-13.15
Concluding remarks
M. Filippi
13.15-14.30
Farewell cocktail
Magnetic Resonance Techniques in Multiple Sclerosis - Eighteenth Advanced Course
Milan, 19-20 March 2015
General Information
REGISTRATION
Registration is free and includes admission to scientific sessions, conference materials,
coffee breaks, lunch and certificate of attendance.
HOW TO REGISTER
All participants are kindly recommended to register via the online registration form at www.biomedia.net
CONTINUING MEDICAL EDUCATION (ECM only for Italian participants)
The event addresses to the disciplines of Neurology, Neurophysiopathology, Neuroradiology. In order
to obtain credits, participants must attend the full educational programme (100% of the meeting) and
pass the final learning test available on line on the site www.providerecm.it.
CERTIFICATE OF ATTENDANCE
A certificate of attendance will be available to each participant at the end of the meeting
OFFICIAL LANGUAGE
English. Simultaneous translation service is not provided.
HOTEL ACCOMMODATION
In case of accomodation please contact:
Biomedia Travel di Biomedia srl
Via L. Temolo, 4 – 20126 Milano
Tel.: 02/45498282 - Fax: 02/45498199 - e-mail: [email protected]
CONGRESS VENUE
San Raffaele Scientific Institute - Aula San Raffaele (c/o Direzione Sanitaria)
Via Olgettina, 60 - 20132 Milano, Italy
HOW TO REACH THE VENUE
 Motorways: San Raffaele Congress Centre can be reached by all motorways, following the direction "Tangenziale Est" (East ring road) till Cascina Gobba exit.
 Subway: San Raffaele Congress Centre is connected to Milan by green subway line.
The subway stop is Cascina Gobba.
 Railway: Milano Central Railway Station is connected to San Raffaele Congress Centre by
subway (green line).
 Airports: Malpensa Airport (50 km) and Linate Airport (5km) are connected to San Raffaele
Congress Centre by railway, bus or taxi.
Magnetic Resonance Techniques in Multiple Sclerosis - Eighteenth Advanced Course
Milan, 19-20 March 2015
5
Magnetic Resonance Techniques
in Multiple Sclerosis
Eighteenth Advanced Course
Milan, 19-20 March 2015
Unrestricted Educational Grant