Curriculum Vitae
P.A.F.M. (Pieter) Doevendans, MD, PhD, FESC
July 2014
Inhoud
PERSONAL DETAILS ................................................................................................................................................... 3
EDUCATION ......................................................................................................................................................................... 3
THESIS ................................................................................................................................................................................. 3
TRAINING ACTIVITIES ................................................................................................................................................ 4
MEDICAL TRAINING ............................................................................................................................................................. 4
SCIENTIFIC TRAINING .......................................................................................................................................................... 4
TEACHING TRAINING ........................................................................................................................................................... 4
GENERAL TRAINING ............................................................................................................................................................ 4
JOB POSITIONS AND HONORS.................................................................................................................................... 5
CURRENT POSITION............................................................................................................................................................. 5
FORMER POSITION .............................................................................................................................................................. 5
PRINCIPAL INVESTIGATOR ................................................................................................................................................... 5
RESEARCH PARTICIPANT ..................................................................................................................................................... 5
ETHICAL SUPPORT PHYSICIAN ............................................................................................................................................. 6
ONGOING STUDIES 2013 ..................................................................................................................................................... 6
EDITORIAL BOARD ............................................................................................................................................................... 6
REVIEWER ........................................................................................................................................................................... 6
IP AND COMPANIES ............................................................................................................................................................. 7
HONORS AND GRANTS .............................................................................................................................................. 8
HONORS .............................................................................................................................................................................. 8
RESEARCH GRANTS OBTAINED ............................................................................................................................................ 8
MEMBERSHIPS ........................................................................................................................................................ 10
NATIONAL AND INTERNATIONAL ACADEMIC PROFESSIONAL ORGANIZATIONS ............................................................... 10
RESEARCH AND TRAINING COMMITTEES .......................................................................................................................... 10
TEACHING ACTIVITIES .............................................................................................................................................. 12
PHD STUDENTS ....................................................................................................................................................... 14
THESIS DEFENSE ...................................................................................................................................................... 18
ORGANISER INTERNATIONAL MEETINGS .................................................................................................................. 22
LECTURES INTERNATIONAL ...................................................................................................................................... 24
LECTURES NATIONAL ............................................................................................................................................... 30
CHAIRMAN ............................................................................................................................................................. 47
PUBLICATIONS ........................................................................................................................................................ 50
INTERNATIONAL ................................................................................................................................................................ 50
DUTCH JOURNALS (NOT LISTED IN PUBMED) ........................................................................................................................... 50
DUTCH LANGUAGE ............................................................................................................................................................ 52
BOOK CHAPTERS ............................................................................................................................................................... 54
BOOK REVIEWS.................................................................................................................................................................. 57
BOOKS ............................................................................................................................................................................... 57
2
PERSONAL DETAILS
Name:
P.A.F.M. (Pieter) Doevendans, MD, PhD, FESC
Address:
Home:
Nieuwegracht 22 A
3512 LR Utrecht
The Netherlands
Phone +31 30 2313476
Office:
University Medical Center
Division Heart and Lungs, dept. of Cardiology, E 03.511
P.O. Box 85500
3508 GA Utrecht
The Netherlands
Phone +31 88 7559801
E-mail [email protected]
Date of Birth
07/24/59
BSN
93582018
Place of Birth
Goirle
Social Security Number 626 60 0110
Citizenship
The Netherlands
Passport number
BIG reg.nr
19020660301
NRK226J43
EDUCATION
School or College
Field of study
Degree Earned
Year
University Leiden
Medicine
Doctoral
1983
University Leiden
Medicine
MD
1985
University Maastricht
Cardiology
Cardiologist
1997
University Maastricht
Molecular Cardiology
PhD
1997
THESIS
Cardiac specific gene expression of the regulatory myosin light chains (ISBN 90 5278 2350) (1997)
3
TRAINING ACTIVITIES
MEDICAL TRAINING
St. Elisabeth Hospital Leiderdorp, Department of Surgery
1985-1986
St Anna Hospital Oss, Departments of Internal Medicine, Surgery,
and Gynaecology and Obstetrics
1987-1988
Academic Hospital Maastricht, Cardiology
1989-1991
Maaslandziekenhuis Sittard, Internal medicine
1992
Academic Hospital Maastricht, Cardiology
1993-1996
Fellow Interventional Cardiology Maastricht
1996-1998
European Resuscitation Council, Advanced Life Support
2010
SCIENTIFIC TRAINING
Research fellow in molecular cardiology at the American Heart Association
Bugher Foundation Center for Molecular Biology, School of medicine,
University of California, San Diego, Dr Kenneth R. Chien.
1993-1994
TEACHING TRAINING
Professional behaviour: to judge and feedback, UMCU
2003
Use of electronic learning environment, UMCU
2004
Docententraining Interactief College Geven, UMCU
2008
Teach the Teachers (basistraining medische vervolgopleiding), UMCU
2009
UMC Utrecht, Basic rules and organization for clinical researchers (BROK)
2010
GENERAL TRAINING
Chief of Clinical Services, Harvard Business School of Public Health, Boston, USA
2013
Advanced Hemodynamic Course, Abiomed, Rome, Italy
2013
Resistant Hypertension Course, Berlin, Germany
2014
4
JOB POSITIONS AND HONORS
CURRENT POSITION
Full professor in Translational Cardiology, UMC Utrecht
May 2004
Chairman department of Cardiology, UMC Utrecht
Jan. 2005
Chairman Renal Denervation Working group, NVVC
2011
Chairman and Medical Manager Division Heart and Lungs, UMC Utrecht
Chairman Board of Advice UMC Utrecht Sports Medicine
April 2012
November 2012
Chairman Steering committee Planning and Capacity, UMC Utrecht
2013
Member Steering committee Refferals and Transmural collaboration
2014
Acting Chairman department of Cardio Thoracic surgery
January 2014 - present
European Society of Cardiology
Member of the Nominating Committee
July 2012
Member EU affairs committee
Sep 2012 - August 2014
FORMER POSITION
Secretary Friends of the Cardiology Foundation
Associate professor in Cardiology, UMC Utrecht
Associate professor in Cardiology, Maastricht,
Programleader CARIM division II Cardiac function
European Society of Cardiology
Chairman of working Group of Cellular Biology of the Heart
Treasurer Council on Basic Cardiovascular Science
2013
Dec. 2002
Nov. 2000 – Dec. 2002
Nov. 2000 – Dec. 2002
Sep. 2006-2012
Sep. 2010-2012
PRINCIPAL INVESTIGATOR
Recombinant human tumour necrosis factor-binding protein-1 (r-hTBP-1) (01-09-2000).
HEBE trial stem cell treatment post MI.
REPERATOR: Atorvastatine to reduce reperfusion injury in acute Myocardial infarction.
DREAMS: Renal Denervation in drug naieve patients with metabolic syndrome and hypertension
DIASTOLE: Renal denervation in patients with preserved LV function and cardiac failure
SMARTCARE: Biomedical Materials
HUSTCARE: HUman STem cells for CArdiac REpair
RESEARCH PARTICIPANT
DAL-OUTCOME: HDL elevation with Dalcetrapib
BEAUTIFUL: Ivabradine: assessing the cardiovascular prevention benefits of a pure heart rate
lowering agent
TICAB: Ticagrelor in cardiac surgery
5
ON Target: The Ongoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial
ETHICAL SUPPORT PHYSICIAN
MODIFY: Ivabradine start 2013
PEGASUS: The Pegasus-TIMI 54 study aims to determine in this group of patients if treatment with
ticagrelor and aspirin will further reduce the risk of subsequent cardiovascular events compared to
aspirin alone.
ONGOING STUDIES 2013
Pharma: EUROMAX; Atomic AHF; EXAMI part 2.
Devices: Protecta Fase I, Protecta Fase II, Simple, EUtrig Treat Clinical Study, Crystal AF, Nectar,
MARC, Madit CRT LIFR registry.
Interventional: AMICI, BAMI, HEBE, Protect, DEBIUT, DEB-AMI, REMEDEE, Pioneer; Dessolve II,
Tryton II, Demonstrate: Cosira; Maya Eu Rapid; Parachute III; Ptolemy 2;
Stem cells: LUMCU HF
EDITORIAL BOARD
Cardiologen Vademecum 1996-2002
Associate Editor
Netherlands Heart Journal
European Heart Journal 2003-2012
Journal of Cellular and Molecular Medicine
World Journal of Cardiology
PLoS One
REVIEWER
Acta physiologica Scandinavica
American Journal Pathology
American Journal of Physiology
Annals of Medicine
Austrian Science Fund (FWF)
BBA - Molecular Basis of Disease
Biochemical Pharmacology
Biomacromolecules
Circulation
Cardiovascular Research
Clinical and Experimental Hypertension
Clinical Physiology and Functional Imaging
EuroIntervention
European Journal of Clinical Investigation
European Journal Heart Failure
European Journal of Physiology
European Journal of Internal medicine
Journal of Biological Chemistry
Journal of Thrombosis and Haemostatis
Molecular Biology Reports
Molecular and Cellular Biochemistry
Nature Protocols
Lancet
Stem Cells Reviews and Reports
6
IP AND COMPANIES
Embryonic stem cells
Mummery Christine, Doevendans Petrus, Tertoolen Leon: Differentiation of human embryonic stem
cells to cardiomyocytes. Es Cell Int Dec, 28 2005: EP1608740; GB2415437
A method for inducing cardiomyocyte differentiation of a hES cell, the method comprising co-culturing
the hES cell with a cell excreting at least one cardiomyocyte differentiation inducing factor or with an
extracellular medium therefrom, under conditions that induce differentiation, cells and cell...
Companies
Leadpharma http://www.leadpharma.com/
Patent application title: PROVISION OF NEW CARDIOMYOCYTE PROGENITOR CELLS AND
CARDIOMYOCYTES DERIVED THEREFROM
Inventors: Marie Jose Goumans (Mijdrecht, NL) Pieter Doevendans (Utrecht, NL)
Assignees: LEAD PHARMA CEL MODELS IP B.V.
Publication date: 2010-08-12
Patent application number: 20100203021
The present invention relates to cardiomyocyte progenitor cells (CMPCs), to methods for their
isolation and to the use of this CMPCs for the provision of cardiomyocytes, by way of differentiating
the obtained CMPCs with a demethylating agent. The present invention also relates to
pharmaceuticals compositions comprising cardiomyocytes for use in a cardiomyocyte replacement
therapy and/or for the treatment in myocardial infarctation or for ameliorating the effects of
myocardial infarctation. Read more: http://www.faqs.org/patents/app/20100203021#ixzz2NQdhrREm
Dutchcardio (converted to International Cardio Corporation, ICC)
Patent application title: IMAGE GUIDED PLAQUE ABLATION
Inventors: Yolande Appelman, Pieter Doevendans, Donald Knight
Patent application number: 20090048546
A method and system for reducing vascular plaque non-invasively comprising the steps of imaging at
at least a portion of a mammalian body to produce an image; determining the location of at least one
vascular plaque in said image; ascertaining the location of the base of said vascular plaque, said
location of base being the target location; precisely determining the relative position of said target
location with respect to the cardiac rhythm in the body; delivering a beam of ultrasound energy waves
waves from a source to the relative position to elevate temperature of said target location in a predetermined manner; monitoring the temperature of the target location; and discontinuing delivery of
ultrasound energy waves when said target location achieves a pre-determined set temperature. Read
Read more: http://www.freshpatents.com/-dt20090219ptan20090048546.php
HONORS AND GRANTS
HONORS
High School, graduate with distinction
1977
Medical school, graduate with distinction
1985
2nd Price Lorex Award 1998, Best Thesis in Cardiology from
1997
First price poster NVVC Najaarscongres 1999
1999
Fellow of the European Society of Cardiology
2000
Honorary Professor Yantai Yuhuangding Hospital, China
2007
Visiting Professor Harvard University USA
2007-2009
Romanian Academy of Medical Sciences (Honorary Foreign Fellow)
2009
RESEARCH GRANTS OBTAINED
-
-
-
NATO Collaborative Research Grant. 1996-1997. Travel grant for collaboration with Robert S.
Kass, University of Columbia, New York USA. "Expression of min K channels in heart".
The Netherlands Heart Foundation: 1997-1999. "The characterization of the regulatory
sequence of the atrial myosin light chain 2 gene".
NIH: "The role of the min K gene". Grant with R.S. Kass.
The Netherlands Heart Foundation: “Hypertrophic cardiomyopathy: early non-invasive
identification of altered myocardial mechanics and coronary flow” (nr. 99.203) with A.C. van
Rossum, VU Amsterdam.
The Netherlands Heart Foundation: “Characterization of the effects of estrogen on cardiac
function under pathophysiologic conditions” (nr. 99.114)
The Netherlands Heart Foundation: “Elucidation of pathogenic genetic pathways in the
hypertrophic and failing heart by micro-array-technology” (nr. 99.122) with H. Smeets,
University Maastricht.
Jan Dekkerstichting en dr. Ludgardine Bouwmanstichting: “Adenovirale gentherapie voor
boezemfibrilleren” (nr. 99-04)
The Netherlands Heart Foundation: “Inhibition of myocardial hypertrophy and dilatation by
viral mediated blockade of intracellular signaling pathways” (nr. 2000.160)
ICIN: Molecular genetic basis of cardiovascular disease (2000)
ICIN: Human genetics and cardiovascular developement (2000)
NHS: Dekker program: Vanessa van Empel (2001-2004)
STW: Stem cell based cardiomyocyte differentiation and classification in 3 D cultures (2003)
BSIK: Weefsel op maat (2003)
Bekales Research Grant – Cardiology 2004, candidature.
Bekales Research Grant (2005)
NHS: Translational medicine: stem cell applications (2006)
ICIN: Stem cells from patients with genetic cardiac disease (2007)
BMM: SMARTCARE: cardiac repair with microtissues (2008)
NIRM: Stem cells as disease models (2009)
ZonMw: TAS (Translationeel Adult Stamcelonderzoek) Cardiomyocyte progenitor cells for
clinical application in cardiac repair (2011)
CVON: HUSTCARE: HUman STem cells for CArdiac Repair (2011)
8
-
Private donations 500 K€ / annually
Annual total funding since 2008 10.000 K€
9
MEMBERSHIPS
NATIONAL AND INTERNATIONAL ACADEMIC PROFESSIONAL ORGANIZATIONS
The Netherlands Society of Cardiology (NVVC)
1994
The European Society of Cardiology (ESC)
1996
American Heart Association, Basic Science Council
1993
American Association for the Advancement of Science
1993
New York Academy of Sciences
1997-2001
European Affairs Committee (European Society of Cardiology)
2010
RESEARCH AND TRAINING COMMITTEES
National: Maastricht
Member: Teaching in Emergency Medicine (University Maastricht) (1995-2000)
Chair: Electrocardiography course for General Practitioners (1997)
Cardiovascular Education Institute (CVOI)
Chair: Courses on Molecular Cardiology, National post-graduate training programme for
cardiovascular medicine (1997-2001)
Chair: Gene Based Treatment, Hands on post-graduate training (1998-2002)
The Netherlands Heart Foundation (NHS)
Member: Committee on the applications of the humane genome project: The Netherlands Heart
Foundation (2000)
Interuniversity Cardiology Institute the Netherlands (ICIN)
Member: working group on genetic basis of cardiovascular disease (ICIN wg 27)
Programme leader: collaboration with NIOB on human genetics and cardiovascular development
University of Maastricht
Elected: Faculty of medicine advisory board (sept 2001)
Consultant Gezondheidsraad
Stem cell research and applications (2002)
ZonMW
Member: VEMI reviewer committee (March 2012 - 2014)
Member: EEK reviewer committee (March 2012 – present)
Member: call committee MKMD (March 2012 – June 2012)
European committee Brussels
FP6&7 reviewer for cardiovascular proposals (2006, 2007)
Advisor for the Board of Healthresearch in The Hague, The Netherlands
Translational Research (2006-2007): Rooijmans HGM, Doevendans PAFM, Hazes JMW, Levi MM,
van der Maas PJ, van’t Veer LJ, Hallemeesch MM, Langeveld CH. Translationeel onderzoek in
10
Nederland. Van kennis naar kliniek. RGO Raad voor Gezondheidsonderzoek. Publ.nr. 55
(ISBN 978-90-5549-649-5).
-
Multidisciplinaire kopgroep Genderverschillen bij Hart- en Vaatziekten (2011)
-
Member NextDx Advisory Board, FP7 project (2012) Next generation integrated MNBSplatform for instant diagnostics with single-molecule resolution
-
Member Committee for Advanced Therapies (CAT), representing clinicians
(July, 1, 2013 – June 30, 2016)
-
Population Health Research Institute, Ontario, Canada (2013)
Steering Committee and National Leader EnligHTNment,
Invited reviewer:
Deutsche Forschungs Gemeinschaft (2006)
Swiss National Science Foundation (2008, 2012)
Danmarks Grundforskningsfond (2009)
New Euroasia Foundation (2013)
Telethon (2006-2014)
11
TEACHING ACTIVITIES
University Maastricht
Member blokplanningsgroep “Acute Nood” (blok 4.5) in 1997, 1998 en 1999.
Member blokplanningsgroep “Adaptatie” (blok 1.4) 2000.
Tutor Ademnood (blok 1.3) 2001 en 2002.
Presentations for PhD-students and medical students
29-03-1995
Molecular Cardiology
17-04-1997
Molecular biology of cardiovascular diseases
21-04-1997
Vascular wall pathology
11-09-1997
Molecular biology of cardiovascular diseases
15-09-1997
Vascular wall pathology
11-05-1998
Genetic factors in the etiology of ischemic
cardiac disease
22-03-1999
Molecular biology of cardiomyopathies
10-06-1999
15-06-1999
Molecular cardiology
Molecular cardiology
13-09-2000
2001
Onderwijsgroep
“Cardiac function and cardiac failure”.
University Utrecht
2003
Pathophysiology Heart and Circulation
2003
ECG
2004
Pathophysiology Heart and Circulation
2005
Pathophysiology Heart and Circulation
2006
2007
2008
2009
2010
2011
2012
2013
2014
Pathophysiology Heart and Circulation
Moleculaire genetica: dilaterend hartfalen
Moleculaire genetica: dilaterend hartfalen
Coronarialijden
Coronarialijden
Acuut Coronair Syndroom
Acuut Coronair Syndroom
Myocardinfarct
Angina Pectoris
PhD-course CARIM
PhD-course CARIM
PhD-course CARIM
PhD-course CARIM
PhD-course CARIM
PhD-course
PhD-course "Moleculaire biologie
van hart en vaten"
CARIM-cursus voor AIO’s
(blok 3.7) UM
“Introductie in de Cardiologie”
Tropenblok 2000-2001
PhD-course
Werkgroep Ischemie
UMC-U
Cursorisch onderwijs
Agios/agnios AZ
Werkgroep Ischemie
UMC-U
Werkgroep Ischemie
UMC-U
Werkgroep ischemie UMC-U
UMC-U
UMC-U
Summa/CRU
Summa/CRU
Summa/CRU
Summa/CRU
CRU
CRU
CVOI/NHS
“Genlezen voor Genezen”: hands-on course, March, Oct 1998. Jan, Sept, Oct 1999
Moleculaire Cardiologie Avonden, June 18, Oct 20, Nov 24 1998. June 16, Sept 15 1999. Sept 20,
Oct 19 2000. Jan 20, May 9, June 14, Sept 20 2001
Stamceltherapie bij hartfalen, cursus Vasculaire Cardiologie, CVOI Utrecht, 2003
“DNA diagnostiek”: CVOI-cursus klinische genetica voor de cardioloog, Sept 26, 2003
Keynote lecture: Clinical Application of COEUR PhCourse stem cells, facts and myths.
12
Erasmus Rotterdam, April 4, 2005
Cursusleider “Cardiomyopathie” CVOI Utrecht, March 31, 2006
OTHERS
HOVO Utrecht “Stamcellen uit het hart, voor het hart”, November 23, 2011, University Utrecht
Medtronic Symplicity Center of Excellence; Training to enhance patient outcomes with renal
denervation (RDN), January 13, 2012, Utrecht, The Netherlands.
General practitioners day, March 22, 2014, Utrecht, The Netherlands, Update reading
echocardiograms.
13
PhD STUDENTS
Name
1.
2.
3.
Xander H.T.
Wehrens, MD
Meindert Palmen,
MD
Thesis
date
2002
2003
Thesis Title
ISBN
Novel insights in the congenital long
QT-3 syndrome
Growth factors in myocardial
ischemia. Focus on FGF-1 and IGF1
Genetic causes of fatal ventricular
arrhythmias
Smoothelins: expression, regulation,
and function
ISBN 90-9015470-1
ISBN 90166424
Roselie
Jongbloed, MD
Sander Rensen,
PhD student (NHS
D97.014)
2003
Bianca van de
Bosch (NHS
99.122)
Fawzi Babiker
(NHS 99.114)
2005
Gene expression profiling in cardiac
hypertrophy and heart failure
ISBN 90-6464225-9
2004
ISBN 909018608-5
7.
Daan Lips, MD
(private funding)
May 2004
Characterization of the effects of
estrogen on the murine heart under
Pathophysiologic conditions
Cardiomyocyte Survival Pathways
8.
Eva van Rooij
(NHS 2000-104)
2004
ISBN 909018810-X
9.
Rutger Hassink,
MD
Arno van Oostrom
MD
June 2004
Novel insights into the
calcineurin/NFAT pathway in cardiac
hypertrophy
Regenerating the heart
11.
Marco Post MD
12.
Vanessa van
Empel MD
Linda W. van
Laake MD
Leo Timmers MD
February
2006
September
2007
April 2008
4.
5.
6.
10.
13.
14.
15.
16.
17.
18.
Peter Westerweel
MD
Dik Versteeg
Hareld Kemps (TU
Eindhoven)
Piet van Vliet
March
2004
March
2005
June 2008
July 2008
December
2008
February
2009
March
2009
Postprandial lipemia and
inflammation in relation to
cardiovascular disease
Closure of cardiac shunts for
migraine relief
Apoptosis inducing factor in cardiac
cell death and cell survival
Cardiac Recovery by Stem and
Progenitor Cells
Mechanisms and Therapeutic
Modulation of Myocardial Infarct
Healing
Vascular progenitor cells in renal
and cardiovascular disease
Toll-like receptor response in
cardiovascular disease
Oxygen uptake kinetics in chronic
heart failure
Somatic cardiac stem cells
14
ISBN 90-9017134-7
ISBN 90646
49049
9789064649042
ISBN 90-3933686-5
ISBN 90-3933726-8
ISBN 909019140-2
ISBN 90-3934116-8
ISBN 978-905278-646-9
ISBN 978-909022808
ISBN
ISBN 978-90393-4838-3
ISBN
ISBN 978-9076014-21-0
ISBN 978-90393-5021-8
Name
19.
Sander de Vos
Thesis
date
April 2009
20.
Pieter Stella
July 2009
21.
Anke Smits
22.
Jakub Regieli
23.
Matthijs Meijs
September
2009
September
2009
October
2009
24.
Arco Teske
November
2009
25.
Bart de Boeck
November
2009
26.
Irene Joziasse
27.
Pierfrancesco
Agostoni
December
2009
December
2009
28.
Simone Post
December
2009
29.
Kim Jie
April 2010
30.
Margriet de Beus
June 2010
31.
Lennart Bongartz
32.
Anneke Hendrix
February
2011
April 2011
33.
Moniek Cox
April 2011
34.
Angelique van
Oorschot
May 2011
35.
Karien van der
Putten
May 2011
36.
Jia Liu
37.
Ben van den
Branden
Henneke Versteeg
August
2011
September
2011
November
2011
38.
Thesis Title
ISBN
Non-invasive cardiac imaging and
the risk of coronary atherosclerosis
Coronary Restenosis: A shifting
paradigm
Cell-Based Cardiac Repair
ISBN 978-90393-5040-9
ISBN geen
nummer
ISBN 978-90393-5130-7
ISBN 978-903935-144-4
ISBN 978-906464-358-3
Towards personalized treatment in
cardiovascular disease
CT coronary angiography and
cardiac MRI in cardiovascular risk
assessment
Echocardiographic quantification of
regional right ventricular systolic
function
Echo-Physiologic Aspects of
Dyssynchrony and
Resynchronization
Genetics of congenital heart disease
Developments in the percutaneous
treatment of obstructive coronary
artery disease
Peripheral blood derived cells and
angiogenesis in cardiovascular
disease
Circulating cells in heart and renal
failure
Sudden Cardiac events in athletes.
The SPORTCORE initiative
The severe cardiorenal syndrome
Sudden cardiac death in the young:
incidence and consequences
Arrhythmogenic right ventricular
dysplasia/cardiomyopathy. Activation
delay, diagnosis and DNA
Progenitor cells from the heart. In
vitro study of CMPC and EPDC
behavior
Anemia and response to
erythropoietin in the cardiorenal
syndrome
Novel Strategies for Enchancing
Myocardial Healing
Innovation in Intervention: New
devices in interventional cardiology
Cardiovascular implantable
electronic devices. The patient
15
ISBN 978-90393-5220-5
ISBN 978-905335-228-1
ISBN geen
nummer
ISBN geen
nummer
ISBN 978-90393-5227-4
ISBN 978-90393-5304-2
ISBN 978-94610-8050-9
ISBN 978-908891-240-5
ISBN 978-905335-352-3
ISBN 978-909026061
ISBN 978-908891-260-3
ISBN 978-905335-388-2
ISBN 978-90393-55930
ISBN 978 94
6108 205 3
ISBN 978 90
5335 450 6
Name
Thesis
date
November
2011
May 2012
41.
Marisevi
Chaldoupi
Jan van der
Heyden
Barbra Backus
42.
Eissa Aguor
43.
Mireille Emans
October
2012
November
2012
44.
Alain van Mil
45.
Marish Oerlemans
46.
Tycho van der
Spoel
December
2012
47.
Margot Bogaard
48.
Anouar Belkacemi
January
2013
February
2013
49.
Krijn Vrijsen
April 2013
50.
Eric Udo
October
2013
51.
Sjoukje Lok
December
2013
52.
Stefan Koudstaal
53.
Frebus van
Slochteren
Jan Willem
Buikema
March
2014
April 2014
39.
40.
54.
June 2012
November
2012
December
2012
May 2014
55.
Wilco Tanis
June 2014
56.
Vinicius Tragante
do O
Kars Neven
June 2014
57.
June 2014
Thesis Title
perspective
Electrophysiological and genetic
insights into atrial fibrillation
Carotid artery stent prior to cardiac
surgery
The HEART score for chest pain
patients
Proton and sodium MRI assessment
of myocardial viability
Red cell dynamics and
haemodynamics in cardiorenal
failure
MicroRNAs novel targets for cardiac
regenerative medicine
Myocardial infarction; Early
diagnosis and cardioprotective
strategies
Optimization of delivery strategies
for cardiac cell therapy in ischemic
heart disease
Optimization of cardiac
resynchronization therapy
A new interventional strategy in
complex coronary artery disease:
drug-eluting balloons; clinical results
and OCT analysis
Exosomes in cardiac injury and
repair
Long-term outcome in contemporary
bradycardia pacing. The followpace
2 study
Myocardial changes in patients with
end-stage heart failure during
continuous flow left ventricular assist
device support
Protection and repair of the ischemic
heart
Technical Solutions to improve
cardiac regenerative therapy
Molecular control of ventricular
growth and cardiomyocyte
proliferation
Novel Imaging strategies for the
detection of prosthetic heart valve
obstruction and endocarditis
Application of bioinformatics in
cardiovascular genomics
Novel energy modalities for catheter
16
ISBN
ISBN 978 90
393 5666 1
ISBN 978 94
610 82855
ISBN 978 90
8891 419 5
ISBN 978 90
8891 50 62
ISBN 978 94
6108 35 93
ISBN 978 90
8891 52 08
ISBN 978 90
8891 52 60
ISBN 978 90
8200 62 09
ISBN 978 94
6108 38 69
ISBN 978 94
6182 18 20
ISBN 978 90
8891 60 14
ISBN 978-90393-6022-4
ISBN 978-909027964-0
ISBN 978-946108-621-1
ISBN 978-908891-862-9
ISBN 978 90
8891 871 1
ISBN geen
nummer
ISBN 978 90
8891 907 7
ISBN 978 94
58.
Name
Thesis
date
Sailay Siddiqi
June 2014
Thesis Title
ISBN
ablation of cardiac arrhythmias
The orchestra of myocardial
regeneration
6108 699 0
ISBN geen
nummer
17
THESIS DEFENSE
-
R.J. van Suylen
E. Creemers
M. Engelen
C. Ruwhof (LUMC)
A. Beningi, referee
P. Sinnaeve
(University Leuven)
- V. Thijssen
- M.A.W. Broeders
- T.B. Twickler
- M.A.M. Stofmeel
- P.J. Senden
- D.L. van der A
- S.G.R. Racasan
- M. Firouzi
- J. Koerselman
- H. Kamphuis
- R. Budde
- C.R.B. Ramakers
- S.M. Boekholdt
- L.H. van den Heuvel
- H.B. de Laat
- B. Langeveld
- J.P.H. van Wijk
- B. Chiappini
- F.H. Rutten
- A.F. van Raamt
- H. Chon
- A. Elvan-Taspinar
September 30, 1999
June 16, 2000
December 14, 2000
January 16, 2001
December 12, 2001
May 2001 Referee, Modulation of nitric oxide/cyclic GMP
signal transduction in the injured vascular wall.
(ISBN 90 5867 143 7)
November 1, 2002
December 5, 2002. Referee, Production and function of
endothelial nitric oxide in the arterial and venous system.
April 29, 2003Referee, Aspects of cardiovascular
endocrinology.
June 1, 2004. Referee, Quality of Life in pacemakers patients.
June 1, 2004. Referee, Skeletal muscle characteristics and exercise
performance in chronic heart failure. A clinical study before and after
physical training.
2004. Referee, Iron and Cardiovascular disease: An epidemiologic
study in middle-aged women.
2004. Referee, The perinatal balance of nitric oxide and
radical oxygen species modulates blood pressure in adult life.
September 17, 2004. Referee, Connexin 40 Gene Variations and
Human Cardiovascular Pathophysiology-molecular Mechanisms and
Clinical Studies.
November 17, 2004, Chair Referees; Coronary collaterals.
January 11, 2005. Referee, In Rhythm: The impact of an ICD
on Quality of life.
March 1, 2005. Referee, Epicardial Ultrasound in Coronary Artery
Bypass Surgery.
March 11, 2005. Referee; Molecular characterization of ionic currents
in the normal and remodeled canine heart.
March 15, 2005. Referee
April 20, 2005, Referee, Methods to evaluate clinical interventions in
cultured porcine coronary arteries.
May 20, 2005. Referee, Characterization of the binding of
antiphospholipid antibodies to ß2-glycoprotein I.
July 6, 2005 Referee, Experimental in-stent restenosis in rats;
The importance of systemic endothelial function.
October 11, 2005, Referee; Metabolic dysregulation and
interventions in type 2 diabetes and HIV-lipodystrophy.
November 21, 2005. Referee, Surgery for atrial fibrillation.
October 4, 2005. Referee, Heart Failure in COPD
March 24, 2006. Referee, Brain damage in patients with manifest
arterial disease.
August 1, 2005. Referee, Gene expression profiling in conditions
predisposing to cardiovascular disease.
September 8, 2005. Referee, Arterial Illness in Pregnancy.
18
- S.F.J. Störk
- S. van der Heide
- L. Smeets
- I. van Langen
- F. Martens
- B. Movassaghi
- J. Iestra
- P. Monraats
- B.A.N. Verhoeven
- J.K. Olijhoek
- A.H.E.M. Maas
- A. Kruit
- M.H. Kamphuis
- S. Sabour
- S.L.M.A. Beeres
- T.P. de Boer
- S.K.G. Winckels
- A. Rutten
- J.W.M. van Eck
- R. Postel
- W. van Dockum
- Bourajja
- A. Beqqali
- M. Mehdi Rastmanesh
- H. el Azzouzi
- J. van Prehn
- E. de Waal
- R. Walhout
- P. Delnoy
November 18, 2005. Chair Referees; Endocrine and
inflammatory markers, atherosclerosos and cardiovascular risk.
November 24, 2005. Referee
November 25, 2005. Referee
November 30, 2005. Referee; Sudden cardiac Death: clinical genetic
aspects.
February 2, 2006. Referee; Vascoreactivity-Insulin Resistance and
vascular effects of Thiazolidinediones.
March 4, 2005 Chair Referees; 3D Rotational X-Ray Coronography.
May 15, 2006, Chairman referees; Prognosis, Proof and Priorities in
Dietetic Practice.
June 6, 2006. Referee; Genetic, Clinical and Experimental Aspects of
Restenosis.
June 22, 2006. Referee; Athero-sclerotic plaque expression, vascular
events and patient characteristics.
June 26, 2006. Referee; Metabolic syndrome and Vascular disease
September 15, 2006. Chair Referees; Breast arterial calcifations and
heart disease risk in women.
September 27, 2006. Referee; Gene polymorphisms in fibrotic
sarcoidosis.
November 3, 2006. Chair Referee; Depression and cardiovascular
disease: the role of diet, lifestyle and health.
July 12, 2007. Referee; Coronary calcifications in healthy women:
risks and risk factors.
October 17, 2007. Referee; Cardiac Bone Marrow Cell Injection for
Chronic Ischemie Heart Diesease.
October 18, 2007. Referee; Physiology of stem cell-derived
cardiomyocytes.
December 20, 2007. Referee; Ventricular electrical remodeling and
arrhythmmogenesis.
February 20, 2008. Referee: Multi-detector row CT of the heart;
methodological evaluation and application in high-risk patients”.
May 15, 2008: Referee: Outcome after pacemaker implantation of
The FOLLOWPACE study”
May 2008: Identification and Characterization of Novel Genes by
Reverse and Forward Genetics in Zebrafish.
Evaluation of the effects of alcohol septal ablation by cardiac
magnetic resonance imaging.
July 2008: Nuclear Factor of Activated T-cells: key regulator of
cardiac hypertrophy and skeletal muscle adaptation.
November 2008: Human embryonic stem cells as a model for
cardiac gene discovery
December 2008: SOCS and inflammation in chronic renal failure
January 2009: Peroxisome proliferatros-activated receptor (PPAR)
regulation in cardiac metabolism and disease
April 2009: dynamic morphology of the aorta
June 2009: advanced cardiovascular monitoring
June 2009: advances in the management and surveillance of
patients with aortic coarctation
October 2009: new clinical insights and innovative techniques to
19
- R. Hoff
- J. Xiao
- A. Oros
- M. Bos
- E. Kaplan
- N. Prakken
- J. Luermans
- T. ten Cate
- J. Brugts
- E. de Pater
- F. Jonker
- L. Nadery
- E. van Waasdorp
- Y. Juwana
- A. van Zuilen
- M. Beijk
- M. Jonsson
- F. Broeyer
- I. Hof
- M. Klomp
- S. Ng
- T. Luijkx
- J. van Keulen
- J. Habets
- R. Bemelmans
- S. Cornelissen
optimize cardiac resynchronization therapy
November 2009: intravascular volume after aneurysmal
subarachnoid hemorrhage
November 2009: development and evaluation of monte carlo-based
SPECT reconstruction
November 2009: pharmacological control of beat-to-beat variability of
repolarization: to suppress and prevent dofetilide-induced Torsades
de Pointes in the anesthetized CAVB dog
January 2010Genetic Basis of Hypertrophic Cardiomyopathy
January 2010: Experimental myocardial regeneration with stem cell
therapy
February 2010: Cardiac MRI of the Athlete’s Heart
February 2010: Paradoxical embolism, migraine, and cardiac shunt
closure
February 2010: Myocardial Perfusion Studies in Abnormal Ventricular
Activation
February 2010: Tailored-therapy of ACE-inhibitors in Coronary Artery
Disease
June 2010: Growth of the zebrafish heart
December 2010: Thoracic Aortic Catastrophes: Towards the
Endovascular Solution
March 2011: Sympathetic hyperactivity in chronic kidney disease:
pathogenesis, clinical relevance and treatment
April 2011: Results of clinical research to improve EVAR
April 2011: Optimizing primary PCI for ST Elevation Myocardial
Infarction
October 2011: Multifactorial approach and superior treatment
efficacy in renal patients with the aid of nurs practitioners
October 2011: PCI of complex coronary leasion new stent
technologies, and clinical outcomes
December 2011: Applicability of human stem cell-derived
cardiomyocytes for safety pharmacology
January 2012: Anthracycline-induced cardiotoxicity a
pathophysiology based approach for early detection and protective
strategies
January 2012: Impact of catheter ablation of atrial fibrillation on the
left atrium
January 2012: Evaluation of novel stent technology: the Genous EPC
capturing stent
January 2012: Conorary collaterals: occurrence and functions
March 2012: Cardiac MRI in athletes
Postuum 2012: Optimalization of endovascular aortic aneurysm
repair by dynamic imaging studies
July 2012: Computed tomography of prosthetic heart valves
June 2012: The effect of physical exercise and resting heart rate on
cardiovascular risk
September 2012: MRI follow-up of abdominal aortic aneurysm status
after endovascular repair
20
- L. de Heer
- S. Achterberg
- J.R. Martina
- S. Dharma
M. Fokkema
- M. Lafeber
- E. Geelen
- M. Schipper
- P. van de Borne
October 2012: Non-invasive imaging of the aorticroot. Towards
optimal evaluation and sizing of stented (tissue engineered) heart
valves
February 2013: Prognosis after cerebral ischaemia of arterial origin:
clinical characteristics and genetic information
February 2013: Continuous-Flow left ventricular assist devices;
clinical and technical aspects
Augustus 2013: Perspectives in the treatment of cardiovascular
disease: from prognostic parameters to therapeutic modalities
November 2013: Optimal Treatment of the ‘High Risk’ Patient with
Carotid Artery Stenosis
December 2013: The polypill in the Prevention of Cardiovascular
Disease
December 2013: Making genetics not so important; families Dealing
with genetic testing for a familial hear disease
Februari 2014: Features of (reverse) remodeling in heart failure
June 2014: Changing Blood Flow in Peripheral Artery Disease
21
ORGANISER INTERNATIONAL MEETINGS
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European workshop on implications of cardiovascular specific gene expression. European
Science Foundation. December 12-14, 1997, Maastricht, The Netherlands
Meeting of the European Section of the International Society for Heart Research (ISHR). June
23-26, 1999, Maastricht, The Netherlands
Mergelland Symposium (1). Diagnostiek en behandeling van acute coronaire syndromen.
November 2, 1999, Valkenburg aan de Geul, The Netherlands
First US-European e-meeting on Molecular Bases of Cardiovascular Diseases. Beyond
monogenic diseases: the challenge of complex cardiovascular disorders. December 9-11,
1999, Paris, France
Vascular Biology Workshop (1): symposium on neoangiogenesis and the endothelium.
January 7, 1999, Maastricht, The Netherlands
Vascular Biology Workshop (2): Angiogenesis and the endothelium. January 13 – 14, 2000,
Houthem, The Netherlands
Vascular Biology. Parke Davis. May 13-17, 2000, San Diego, USA
Mergelland Symposium (2): Cardiac Failure November 7, 2000, Valkenburg aan de Geul,
The Netherlands
Mergelland Symposium (3): Endotheel en bloedstroom October 31, 2001, Valkenburg aan
de Geul, The Netherlands
Workshop (3): St. Gerlach Vascular Biology Workshop: January 11-12, 2001, Maastricht,
The Netherlands
European workshop on Cardiovascular genomics: new pathophysiological concepts European
Science Foundation: November 29- December 1, 2001, Maastricht, The Netherlands
Workshop (4): St. Gerlach Vascular Biology Workshop: January 24-25, 2002, Maastricht.
PV-LOOPS International Symposium on ventricular function and failure from mice to man:
January 17-19, 2002, Maastricht, The Netherlands
Mergelland Symposium (4): Het hartritme bij de patiënten met een hoog risico prettig
geregeld. November 27, 2002, Valkenburg aan de Geul, The Netherlands
Workshop (5): St. Gerlach Vascular Biology Workshop: January 30-31, 2003, Maastricht,
The Netherlands
Update in Molecular Cardiology 2003, March 29, 2003, San Diego, USA
Voordracht prof. Brutschaert: “Diastolisch hartfalen”: April 27, 2004, Utrecht, The
Netherlands
HLCU symposium “Translational Medicine”: April 14 and 15, 2005, Zeist, The Netherlands
Heart Failure Association Winter Research Meeting (1, Garmisch). January 25-28, 2006
th
4 Dutch - German Joint Meeting of Molecular Cardiology, February 9-11, 2006, Utrecht, The
Netherlands
Second HLCU Symposium on Translational Medicine; Cardiovascular disease:
multidisciplinary approaches for multifactorial diseases. November 21-22, 2006, Zeist, The
Netherlands
Heart Failure Association Winter Research Meeting (2, Garmisch). January 25-28, 2007
The Heart and kidney, fatal twins. October 10, 2007, Amersfoort, The Netherlands
Heart Failure Association Winter Research Meeting (3). January 25-28, 2008, Garmisch,
Germany
Nucleusmeeting WG cellular biology, February 22, 2008, Utrecht, The Netherlands
GUCH, Grown-ups with Congenital Heart Disease, October 24, 2008
22
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-
Cardiorenal 2008, Mechanisms for adverse outcome in Heart and Kidney failure, October 28,
2008, Utrecht, The Netherlands
Netherland Hart Days, January 2009, Curaçao, Netherlands Antilles
Heart Failure Association Winter Research Meeting (4). January 24-28, 2009, Diablerets,
Switzerland
New challenges and frontiers in interventional cardiology, as part of doctorate P.R. Stella, July
8, 2009, Amerongen, The Netherlands
Sudden Cardiac Death and 25 Years ICD Therapy, October 2, 2009, Utrecht, The
Netherlands
EUGeneHeart General Assembly and Seminar, November 25-27, 2009, Utrecht, The
Netherlands
The cardiorenal syndrome; one common pathophysiological process or a mechanistic melting
pot?, November 26, 2009, Amsterdam, The Netherlands
1e Cardiologie Avond regio Utrecht: “Meet the Experts”, December 2, 2009, Utrecht, The
Netherlands
Netherlands Hart Days, January 28-30, 2010, Curaçao, Netherlands Antilles
Symposium Cardiovascular genetics in clinical practice: When and how?, December 15,
2010, Utrecht, The Netherlands
Netherlands Hart Days, January 27-29, 2011, Curaçao, Netherlands Antilles
Cardiomyocyte Regeneration and Protection, June 20 – 21, 2011 La Jolla, California, USA
Symposium Innate Immunity and Cardiovascular Disease, September 5, 2011, Utrecht, The
Netherlands
Steunhart, een alternatief voor Harttransplantatie? September 14, 2011, Utrecht, The
Netherlands
International Conference on the CIED patient perspective: 'Living in a Device World: Focus on
Recent Challenges and Tools to Improve Clinical Care for Patients with an Implantable
Cardioverter Defibrillator', November 3-4, 2011, Tilburg, The Netherlands
Symplicity Center of Excellence, training to enhance patient outcomes with renal denervation,
January 13, 2012, Utrecht, The Netherlands
Symplicity Center of Excellence, training to enhance patient outcomes with renal denervation,
June 8, 2012, Utrecht, The Netherlands
Symposium “Passion for rhythm”, June 8, 2012, Utrecht, The Netherlands
Symposium “Topzorg anno 2012: Opening nieuwe HCK, September 28, 2012, Utrecht, The
Netherlands
2nd Utrecht Stem Cell Conference, June 11, 2013, Utrecht, The Netherlands
Cardiovascular Treaty of Utrecht, September 12, 2013, Utrecht, The Netherlands
Symposium “The meeting point of the adult roundabout”, In conjunction with SailaySiddiqi’s
Thesis Defense on‘Orchestration of MyocardialRegeneration’, June 25, 2014, Utrecht, The
Netherlands
23
LECTURES INTERNATIONAL
1995
-
1996
-
1997
-
1998
-
1999
2000
-
Cellular electrophysiology and immunocytochemistry of single isolated murine embryonic
cardiomyocytes. Dept. of internal medicine, Bonn, Germany.
The atrial myosin light chain gene and atrial arrhythmias. Dept. of biochemistry, New
Orleans, LA, USA.
Characterization of the regulatory sequence of the atrial myosin light chain 2 gene.
Dept. of Cardiology, Max Planck Institute, Bad Nauheim, Germany.
The atrial myosin light chain two gene: Wyeth-Ayerst Research, Princeton, New Jersey,
USA.
The regulatory sequence of the atrial myosin light chain two gene. Dept. of pharmacology,
Columbia University, New York, USA.
Characterization of the MLC-2a promoter. Dept. of Cardiology, Lübeck, Germany.
Molecular Cardiology. Karolinska Institute, Center of Molecular Medicine, Stockholm,
Sweden.
Cardiac Expression of the Regulatory Myosin Light Chains. ESF Workshop, Maastricht, The
Netherlands.
Genetically engineered animal models of heart failure: Problems and Perspectives. XVI World
Congress of the ISHR, Rhodos, Greece.
Apoptosis in the Cardiovascular System. MitoKor, San Diego, USA.
Molecular cardiovascular biology: a perspective. XVI Corso di Emodinamica e
Cineangiografia, Baveno, Italy.
Molecular approach to neoangiogenesis. Symposium on Neoangiogenesis and the
Endothelium, Maastricht, The Netherlands.
An introduction in gene therapy, where are we, what can we expect? Symposium "Int.
Cardiology Towards the New Millenium”, Eindhoven, The Netherlands.
Antiarrhythmic drugs. Vth Interlaken Meeting, Interlaken, Switzerland.
The role of genetics and genomics in cardiac disease. ALMA-meeting, Luik, Belgium.
Cardioprotection and vasculogenesis by FGF overexpression. 2nd Workshop on
angiogenesis and the Endothelium. Valkenburg, The Netherlands.
Interactive Session: Heart Failure and Vascular Disease. UCSD Molecular Cardiology
Educational Program. Introduction to Molecular Biology for Cardiologists, San Diego, USA.
Gene therapy: Which vector? Congress of the European Society of Cardiology, Amsterdam,
The Netherlands.
Gene therapy approaches for myocardial angiogenesis. Congress of the European Society of
Cardiology, Amsterdam, The Netherlands.
Towards new therapies in heart failure: Keiyo University, Tokyo, Japan.
Therapeutics possibilities by molecular genetics in heart failure, Scientific Exchange Visit
24
2001
-
2002
2003
-
-
Oxford, UK.
Molecular Cardiology, basis principles Meeting on Science and Development, Boston, USA.
Genetic approaches in thrombolic coronary syndromes, 3thd Vascular Biology Workshop,
Valkenburg, The Netherlands.
Growth Factors and Myocardial function: Krannert Institute of Cardiology, Indianapolis, USA.
Clinical Symposium Heerlen: “Gene therapy in hypertrophic and dilated cardiomyopathy”,
Vaals, The Netherlands.
Human Embryonic Stem Cell derived Cardiomyocytes: potential for postischemic myocardial
repair, AHA, Myocardial ischeamia, Seattle, USA.
Embryonic Pluripotent Stem Cells: XXIII Congress of the European Society of Cardiology,
Stockholm, Sweden.
Molecular pathways and therapies. Estrogen antagonizes cardiomyocyte hypertrophy by
autocrine/paracrine stimulation of a guanlyl cyclase-A receptor-cGMP-dependent protein
kinase pathway AHA, Anaheim, USA.
Multigenic analysis of cardioavscular disease 4thd vascular biology workshop, Valkenburg,
The Netherlands.
Signalling pathways involved in left ventricular remodeling, ESC Berlin, Germany.
Left ventricular function assessment in mouse, San Diego, USA.
PV-loops in the mouse heart, MICABG workshop, Monaco, France.
Gen therapie : Vlaams ned Cathlab symposium, Maastricht, The Netherlands.
Genetic polymorphisms and cardiac disease: Low Output Syndrome revisited, AMC
Amsterdam, The Netherlands.
Congress of the International Academy of Pathology, Amsterdam, The Netherlands.
Approach of multigenic disease. 5th Vascular Biology Workshop, Valkenburg, The
Netherlands.
Myocardial stem cells, Cardiology Update 2003, 15th International Postgraduate Course on
Cardiovascular Disease, Davos, Switzerland
Potentials of stemcells in cardiovascular research, New Trends in Cardiovascular Biology:
Bridging the Gap between Clinical Practice and Basic Science, Bernried, Germany.
Cardiac phenotyping in the mouse, Update in Molecular Cardiology 2003, Seatlle, USA.
Angelo Scandinavian Cardiac Outcomes Trial, The Netherlands.
Second Dutch-Italian cardiology exchange: From cardiac hypertrophy to failure, Pisa, Italy.
Heart Failure ESC/ISHR meeting, Estradiol as an anti hypertrophic agent, Strasbourg,
France.
Annual meeting Turkish College of Cardiac Surgeons. Istanbul, Turkey.
Stemcell applications in cardiovascular disease. ESC congress: Estrogen actions in the heart;
Chairman’s summary: Therapeutic use of stem cells: ready for prime time?; Presence and
therapeutic potential of stem cells in coronary artery disease, Vienna, Austria.
NSCC Conference 2003: The cardiomyocyte phenotype in cardiogenesis in mouse and man,
Melbourne, Australia.
Potentials of stemcells in cardiovascular research, Munich, Germany.
25
2004
-
2005
2006
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Stem cells for Cardiac Repair, Norderstedt, Germany.
Stem cells in clinical investigation, The 38th annual scientific meeting of European, Society for
Clinical Investigation, Utrecht, The Netherlands.
Europa – Pergene substudy, Scientific committee meeting, Schiphol, The Netherlands.
Cardiac Tissue Repair Cell Transplant & Growth Factors, Sirmione (Lake Garda), Italy.
Academic session Life-Sciences NV, Edegem, Belgium.
Stemcell Treatment for Myocardial Regeneration at ES Cell International, Singapore.
Estrogens block cardiac hypertrophy ISHR, Brisbane, Australia.
Genomics of hypertrophy signalling in zebrafish, 2nd Project Meeting EUGene heart,
Frankfurt, Germany.
Myocardial hypertrophy and estrogen receptors, Berliner Symposium. Geschlechterforschung
in der Medizin, GiM, Berlin, Germany.
Embryonic Stem Cells in Cardiac Repair, Stemcell Colloquium 2004, Maastricht,
The Netherlands.
Stem cell therapy for patients with acute myocardial infarction and relevant experimental
models, Gent, Belgium.
Role of Genes in Cardiology Emex-Apicon-2005, Bombay, India.
Controlling cardiomyocyte survival and cardiac function, Heartfailure. London, United
Kingdom.
ESC congress 2005, Stockholm, Sweden.
Stem Cell Application for Cardiac Repair, Guidant, August 19, San José, USA.
Stem cell Transplantation: October, ESI, Singapore.
Stem cells for cardiac repair: Meeting on translational medicine, October, Bonn, Germany.
Stem cells for Cardiac Repair Cardiovascular Cell and Gene Therapy Conference III, April 2424-26, Cambridge, USA.
New frontiers in protection against atherosclerosis: A glance at the future “Stem cells and
gene therapy for myocardial regeneration”, June 6, Noordwijkerhout, The Netherlands.
The Basics of Mesenchymal Stem Cells Stem Cell Symposium during AO ASIF Foundation
Trustees Meeting 2006, June 15-18, Berne, Switzerland.
Molecular mechanisms – estrogen signaling in the heart Heart Failure 2006, June 17-20,
Helsinki, Finland.
Cardiac Progenitor Cells, The Cardiovascular Institute and The Pennsylvania Muscle Institute,
September 20, Philadelphia, USA.
Review meeting of the German Research Foundation Clinical Research Unit KFO 123/2 Lung
Transplantation, September 26 - 27, Hannover, Germany.
Vascular medicine: new frontiers Stem cells and gene therapy for myocardial regeneration,
Cardiovascular exchange summit, For internists and cardiologists from The Netherlands and
Spain, September 28, Valencia, Spain.
Biological Therapy in Heart Failure. Stem Cell Therapy in Cardiology-Present and Future
Trends Cardiology Summit Oct 6-8, Mumbai, India.
Human cardiac progenitor cells for myocardial repair, 4th Annual CHFR Symposium, Center
for Failure Research, Oct 12, Oslo, Norway.
26
2007
-
-
2008
-
-
The European Society for Heart and Lung Transplantation “The future of heart
transplantation: cells versus devices”, Jan 16-19, Wengen, Switzerland.
Winter meeting on Translational Basic Science of the Heart Failure Association (HFA) of the
European Society of Cardiology (ESC) “From cardiac adaptation to failure and back”,
‘Precursor cells from human atriuim’ Jan 24-27, Garmisch-Partenkirchen, Germany.
nd
“Cardiac Progenitor Cells For Science and Therapy” Interventional Cardiology 2007, 22
annual international symposium, March 11-16, Snowmass Village, Colorado.
Arbeitsgruppe Stammzellen, April 12-14, Congress Centre Mannheim, Germany.
Seminar, June 21 – 25 2007, Trondheim, Norway.
Stem Cells in Cardiac Repair Turijn Molecular Biothechnology Centre University of Torino
Eugene meeting, Nov 29, Torino, Italy.
Potassium Inward Rectifier Expression Is Regulated by TGFB and BMP in Human
Cardiomyocyte Progenitor Cells, AHA Sessions 2007, November 3 – 9, Orlando, USA.
UCSD: Somatic cardiac stem cells, January 3, San Diego, USA.
Reperfusion injury post MI Interventional Cardiology 2008, 23rd Annual International
Symposium, March 9-14, Colorado, USA.
Stem cells for Cardiac repair, Invited seminar speaker April 29, Gottingen, Germany.
Autologous stem cells and cardiac repair: towards a paracrine explanation
European Section Meeting of the International Society for Heart Research, May 28-31,
Athens, Greece.
Progenitor cells for cardiac repair, HFA, Milan, Italy.
Reprogramming of adult-derived cells into the myocardial lineage. Riley Heart Center
Symposium on Cardiac Development, September 9, Indianapolis, USA.
ESC Congress, An integrated view of cardiac development, Valve morphogenesis and
dysmorphogenesis, Cardiac Progenitor cells. September 1-3, Munchen, Germany.
Lage Landen congres, Stemcells and paracrime effects, September 28, Rome, Italy.
Cardiac Progenitor Cells, Sapienza university, September 26, Rome, Italy.
2009
Symposium Interventional Cardiology 2009, March 8-13, Snowmass Village Colorado, USA
Nederlandse Hartdagen, Curaçao, Netherlands Antilles.
Symposium State of the Heart: Heart evidence: putting science into practice, March 27,
Utrecht, The Netherlands.
Congres Heart Failure Association ESC/ISHR, May 30 – June 2, Nice, France.
Seminar Perspectives of cardiac stem cell therapy: what is the optimal cell type? June 8,
Hamburg, Germany.
Meeting Translating cellular mechanisms to therapeutic targets, April 30 – May 3, Villa
Monastero, Italy.
Symposium Cardiac Stem Cells differentiation and Biopsy-derived Cardiac Regenerative
Cells: clinical implications of basic research, October 14-16, Rome, Italy.
Cardiovascular Imaging seminar Coronary angiography: life cases in catheter lab, 26-8
October 26- 28, Yantai, China.
6e National Symposium, Human cardiac progenitor cells from science to bedside and back.
November 3-6, Bucharest, Romenia.
AHA Genetic mechanisms of collateral growth: translational views, November 15, Orlando,
USA.
27
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2010
-
2011
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CSCS Cardiac progenitor cells UCSD, November 20, San Diego, USA.
USD, November 21, San Diego, USA.
e
Symposium 5 Cariorenaal failure The cardiorenal syndrome: one common pathophysiological
process or a mechanistic melting pot?, November 26, Amsterdam, The Netherlands.
Netherlands Heart Days 2010, January 28-30, Management of acute cardiac disease,
Curaçao, Netherlands Antilles.
FEAM conference, March 24- 26, Cardiac stem cells, form science to therapy, Bucharest,
Romenia.
ESC Congress, Heart Failure, May 29 – June 1, Title: Disease modeling with adult cardiac
stem cells Berlin, Germany.
ESC Congress, Frontiers in Cardiovascular Biology, July 16-19, Title: Toll-like receptors:
monocytes and the vasculature, Berlin, Germany.
Colloquium ‘Cardiovascular Science in Europe’, October 4-5, Title: Trends in prevention and
cure of cardiovascular disease, Brussels, Belgium.
nd
22 WECOC, October 29-31, Titles: Facts and Fictions in Regenerative Cardiovascular
Medicine Developing CV services networking in primary care, Jakarta, Indonesia.
th
The 13 La Jolla-International Cardiovascular Research Conference, March 11-13, La Jolla,
California, USA. Title: Enchancing Cardiac Stem Cell Differentiation into Cardiomyocytes
th
26 Annual International Symposium Interventional Cardiology, March 13-18, Aspen,
Colorado, USA. Title: Microtissues to Repair the Heart
Symposium: Psychological triggers of acute cardiac events, June 10, Tilburg, The
Netherlands. Title: The biology of acute coronary syndromes; the role of triggering events
Cardiomyocyte Regeneration and Protection, June 20-21, La Jolla, California, USA. Title:
Cardiac repair through cardiac stem cells
EHRA Europace 2011, June 26-29, Madrid, Spain. Title: Electrical characteristics of human
cardiac derived cardiomyocytes
University of Leicester, November 28, 2011, Leicester, United Kingdom, “Stem cells from the
heart”
The Holst Symposium, December 16, 2011, Eindhoven, The Netherlands, Title: Cardiac
Stem Cell: Worker of Factory?
2012
Symplicity Center of Excellence, training to enhance patient outcomes with renal denervation,
January 13, 2012, Utrecht, The Netherlands. Title: Future of RDN and practical
considerations, difficult cases
Symposium “Translating cardiovascular research, between East and West, April 26, 2012
Utrecht, The Netherlands, Title: Cardiac stem cells; the solution
th
27 Annual International Symposium Interventional Cardiology, March 4-9, Aspen, Colorado,
USA. Title: Tissue engineering for the heart
EuroPCR, May 15-18, 2012, Paris, France. Title: Take home message: Renal Denervation
Academy Colloquium KNAW, May 31 – June 1, 2012, Amsterdam, The Netherlands, Title:
Renal denervation: a new treatment option in resistant arterial hypertension
th
10 World Congress or the International Society for adaptive medicine, June 7-10, 2012,
Bucharest, Romania. Title: Cardiac stem cells: the solution
28
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3rd Lugano Stem Cell Meeting, June 25-26, 2012, Lugano, Switzerland, Title: Role of
exosomes in stem cell-mediated paracrine mechanisms
th
24 WECOC, October 19-21, Titles: Cardio Renal Syndrome; Cardiologist point of view and
Multi modality imaging approach in CAD: Which for What?, Jakarta, Indonesia.
th
Annual meeting CALN, 10 Chinese-Dutch Life Sciences Forum, November 24, 2012,
Leiden, The Netherlands, Title: What does the heart need, stem cells or exosomes.
2013
28th Annual International Symposium Interventional Cardiology, March 24-29, Aspen,
Colorado, USA. Title: The future of cardiac stem cells
th
47 Annual Scientific Meeting ESCI, April 17-20, Albufeira, Portugal. Title: Role of gender in
sudden cardiac death
ESC Congress 2013, August 31 – September 4, 2013, Amsterdam, The Netherlands.
Session TOP 5 in Invasive Cardiology “Why and which patient to refer” Title: Resistant
Hypertension treated with renal denervation
Grand rounds lecture Krannert Institute of Cardiology Indiana University School of Medicine,
October 29, 2013, Indianapolis, Indiana, USA. Title: Do stem cells know what to do.
rd
3 Utrecht symposium on advanced heart failure: a glimpse into the future, November 22,
Utrecht, The Netherlands, Title: Summary and Closure
2014
th
29 Annual International Symposium Interventional Cardiology, March 9-14, Aspen,
th
Colorado, USA. Title: Cardiac Repair48 Annual Scientific Meeting of ESCI, April 30 – May 3,
Utrecht, The Netherlands. Title: Estrogens to maintain or improve cardiac function
Symposium “The meeting point of the adult roundabout”, June 25, 2014, Utrecht, The Netherlands.
Title; Welcome speech, introduction and closure
29
LECTURES NATIONAL
1995
20 januari
Introduction to molecular cardiology
AZM
3 februari
Genecloning
AZM
15 februari
Cellular electrophysiology and immunocytochemistry of
single isolated murine embryonic cardiomyocytes
San Francisco
7 maart
In situ hybridization and PCR: new diagnostic tools
AZM
13 maart
Cellular electrophysiology and immunocytochemistry of
single isolated murine embryonic cardiomyocytes
Bonn (D)
17 maart
Myosin light chain expression and
heart chamber specification
CARIM
29 maart
Molecular Cardiology
AIO-cursus
CARIM
18 mei
Murine transgenic and gene targeting technology
in cardiovascular research
AZM
30 mei
adrenergic receptors in the heart: Rhone
new experimental animal studies
Poulenc
16 juni
De retinoid-X Receptor is essentieel voor een
normale ontwikkeling van het muizenhart
Ass Symp
AZM
21 augustus
The green fluorescent protein as in vivo reproter
gene in cardiomyocytes and other mammalian cells
ESC A’dam
20 oktober
Cardiac gene transcription
AZM
3 november
The atrial myosin light chain 2 promoter
AZM
2 december
Gene therapy in vascular biology
AZM
The atrial myosin light chain 2 regulatory gene
Dept. of biochemistry
New Orleans, LA,
USA
1996
21 maart
18 september Characterization of the regulatory sequence of
Dept. of experimental the atrial myosin light chain 2 gene
Cardiology, Max Planck Institute
Bad Nauheim
14 november Characterization of the atrial myosin light chain 2
Dept. of pharmacology regulatory sequence
Columbia University
New York
30
15 november The atrial myosin light chain 2 gene
Wyeth Ayerst Research
Princeton, NJ
1997
10 januari
North, South, West ...? About slots and blots!
AZM
11 april
Molecular genetics of cardiomyopathies
AMC
Knollsymposium
17 april
Molecular biology of cardiovascular diseases
AIO-cursus CARIM
21 april
Vascular wall pathology
AIO-cursus CARIM
29 mei
Molecular cardiology in clinical practice
Dutch Internal Med.
Society
30 mei
Course on Molecular cardiology in the Netherlands
CVOI
20 augustus Characterization of the MLC-2a promoter
Dept. of Cardiology
Lübeck
22 augustus Molecular Cardiology
Karolinska Institute,
Stockholm. Center of
Molecular Medicine
11 september Molecular biology of cardiovascular diseases
AIO-cursus CARIM
15 september Vascular wall pathology
AIO-cursus CARIM
25 oktober
Cardiac problems in Friedreich's Ataxia
Euro-Ataxia Meeting,
Lunteren
29 oktober
Weefselspecifieke en induceerbare promotoren
ICIN
21 november Molecular genetics of cardiomyopathies
AZM
13 december Cardiac expression of the regulatory myosin
European Science Foundationlight chains workshop
Castle Vaeshartelt
Maastricht
1998
5 maart
Pathophysiology of endothelial dysfunction.
Menarini Company
15 april
Moleculaire evaluatie van cardiomyopathieën.
ICIN Projectdag
11 mei
Genetische factoren bij het ontstaan van
ischemische hartziekten.
AIO-cursus
13 mei
Hypertrofe cardiomyopathie: de relatie tussen
VU, Amsterdam
31
genotype en fenotype.
mei
Genetically engineered animal models of heart
World Congress of the failure:
Problems and Perspectives.
XVI
ISHR
Rhodos, Greece
18 juni
Cardiovasculaire biologie
Moleculaire
Cardiologie Avond,
CVOI
24 juni
Ritmestoornissen
Hartcursus
Huisartsgeneesk.
7 juli
Muis-electrofysiologie
HoofdlijnRitme AZM
6 oktober
Cardiac expression of the regulatory myosin light Vakgroep
Endocrinologie chain
8 t/m 11 okt. Symposium Oostelijk Cardiologisch Genootschap
Praag
19 oktober
Moleculaire cardiologie: Atherosclerose
Zeeland
Negende Symposium
Oosterscheldeziekenhuizen
20 oktober
Moleculaire aspecten van celdood
Moleculaire
Cardiologie Avonden,
CVOI
2 november
Cardiac specific expression of the regulatory myosin
light chains
Institut für Genetik, Bonn
3 november
Molecular Cardiology for the Clinician
Bijeenkomst LVH,
Roosteren
12 november Apoptosis in the Cardiovascular System
MitoKor, San Diego
21 november Molecular cardiovascular biology: a perspective.
XVI Corso di
Emodinamica
Cineangiografia,
Baveno
24 november Moleculaire genetica en genexpressie.
Moleculaire
Cardiologie Avonden,
CVOI
32
1999
7 januari
Molecular approach to neoangiogenesis. Symposium on
Neoangiogenesis and the Endothelium
Maastricht
14 januari
Cellulaire adaptatie bij ischemie.
12e Lauswolt symposium
Beesterzwaag
5 februari
An introduction in gene therapy, Symposium
"Int. Cardiology where are we, what can we expect?
Towards the New Millenium",
Eindhoven
15 februari
Antiarrhythmic drugs
Vth Interlaken
Meeting
22 maart
Moleculaire biologie van cardiomyopathieën. AIO-cursus
"Moleculaire biologie van hart en vaten"
9 april
Hypertrofie en hartfalen. Boerhaave symposium
Leiden
13 april
Gen-lezen-genezen? Symposium
St. Annaziekenhuis,
Geldrop
20 april
Basic Science and Molecular Cardiology.
ACCSAP-cursus,
St.Annaziekenhuis,
Geldrop
28 mei
Lipiden en risicomanagement.
Nascholingscursus
BMS, Vineuil-SaintFirmin, Frankrijk
31 mei
Moleculaire aspecten van duursport. Cursus “Medische
Aspecten Genetische aspecten van hypertrofie en
Duursport”, DNA doping
Sederon, Frankrijk
5 juni
Moleculaire cardiologie: VEGF.
NVVC Juniorkamer,
Noordwijk aan Zee
10 juni
Moleculaire cardiologie.
CARIM-cursus voor AIO’s
15 juni
Moleculaire cardiologie. Blok 3.7, “Introductie in de
Cardiologie”,
UM
16 juni
Cardiovasculaire biologie.
Moleculaire
Cardiologie Avonden,
CVOI
24 juni
Klinische toepassing van moleculaire cardiologie.
Refereeravond Catharina Ziekenhuis
Eindhoven
8 oktober
Moleculaire biologie voor de clinicus.
STOA-cursus,
33
Athene
12 oktober
Moleculaire biologie voor de clinicus.
ACCSAP,
Apeldoorn
14-22
november
Risicoprofielanalyse van cardiovasculaire
aandoeningen.
Huisartsencursus,
Cuba
6 december
The role of genetics and genomics in cardiac disease
.
ALMA-meeting,
Luik
Cardioprotection and vasculogenesis by FGF
2nd Workshop on Angiogenesis overexpression
and the Endothelium.
Valkenburg
31 januari
Isolation of mRNA and construction of cDNA
libraries from human endomyocardial biopsies.
2nd Int
Cardiovascular
Genomics, Miami,
Florida
9 februari
Genetische variatie in hart- en vaatziekten.
Symposium Roche
Chemie Gebruikers
Groep
23 februari
Klinische genetica.
AIO-cursus:
Pathologie en
pathofysiologie van
vaatafwijkingen
29 maart
Hypertrophy.
AIO-cursus
5-8 april
Hands-on: praktische DNA-diagnostiek.
Nascholing voor
internisten,
Novartis, Sardinië
8-11 april
DNA-diagnostiek: wat is uw genotype?
Nascholing voor
cardiologen,
Novartis, Sardinië
8 mei
Genetische factoren bij ischemische hartziekten.
5022: Pathofysiologie en pathologie
van ischemische hartziekten.
AIO-cursus
23 mei
Moderator ACCSAP
Geldrop
8 juni
Genetische ontvankelijkheid voor cardiovasculaire
NUTRIM-cursus: Genetic ziekten. Variations and the
consequences for health.
2000
14 januari
34
13 juni
Moleculaire cardiologie. CVOI. Bijeenkomst MSD:
Van Cholesterolverlaging naar endotheelfunctieverbetering.
27 augustus Gene therapy: Which vector?Congress of the ESC.
Amsterdam
30 augustus Gene therapy approaches for myocardial angiogenesis.
Congress of the ESC
Amsterdam
20 september Moleculaire cardiologie avonden: ritmestoornissen
CVOI Oudaen
Utrecht
6 oktober
Therapeutics possibilities by molecular genetics in
Scientific Exchange heartfailure
Visit Oxford
7 oktober
Moleculaire cardiologie: de link naar de praktijk
uPDate Internisten
Cardiovascular
Disease
Amsterdam
8 oktober
Moleculaire cardiologie: de link naar de praktijk
uPDateCardiologen
Cardiovascular
Disease
Amsterdam
13 oktober
Molecular cardiology, basic principles.
Meeting on Science and Development
Boston
19 oktober
Moleculaire Cadiologie avonden:
ritmestoornissen
CVOI, Utrecht
20 oktober
Hartspiercellen: inzicht in erfelijke hartspierziekten CCMO, Den Haag
en transplantatie
21 oktober
Het endotheel als poortwachter van het hart Medical Davinci,
Noordwijk
26 oktober
Power of Molecular Cardiology
Medtronic, Maastricht
3 november
Genetische defecten van contractiële elementen
CVOI Utrecht
4 november
Veranderende inzichten in de pathofysiologie van de
hartfalen
Het Roche
Drielanden
Forum Vaals
6 november
Betekenis van betablokkers bij hartfalen
Huisartsen,
Meerssen
7 november
Symposium hartfalen Mergelland
Valkenburg a/d Geul
35
18 november Veranderende inzichten in de pathofysiologie van de
Het Roche
Drielanden Forum
Vaals
20 november Implementation of molecular cardiology into clinical
cardiology
Canisius Nijmegen
Opleidingscursus
cardiologie
23 november Genetische defecten van contractiële elementen
CVOI Utrecht
30 november ACCSAP Basic Science and Molecular Cardiology
Nijmegen
08 december Interventies in coronairlijden: van basis naar kliniek
Grip cursus
Utrecht
2001
12 januari
Genetic approaches in thrombotic coronary syndromes
Vascular Biology Workshop St Gerlach
Maastricht
15 januari
Endotheel en NO
Heeze
12 februari
Growth Factors and Myocardial Function
Maastricht
7 maart
Stem cells: potential for treatment of cardiac disease?
ICIN/NIOB, Utrecht
5 april
Biotherapie in de kliniek
e
3 Symposium voor research-medewerkers OLVG
Amsterdam
Gen-therapie bij coronairlijden
Novartis congres 2001 Vasculaire geneeskunde:
Madeira
21 april
“Genen en hartziekte”
Maastricht
9 mei
Moleculaire cardiologie avonden. Hartfalen CVOI
Utrecht
14 juni
Moleculaire cardiologie avonden. Hartfalen CVOI
Utrecht
8 april
5 september Embryonic pluripotent stem cells
ESC/Stockholm
12 september Moleculaire cardiologie in de kliniek
Nieuwegein
12 september Genetic causes and cures of cardiac disease
The AIO course
Garderen
14 september Molecular adaptatie bij myocard hypertrofie
Velp
20 september Moleculaire cardiologie avonden. Hartfalen CVOI
Utrecht
2-4 oktober
Indianapolis
From hypertrophy to failure
36
31 oktober
Mergelland Symposium “Endotheel en bloedstroom”
Juliana/Valkenburg
1-3 november Roche Drielanden Forum
Vaals
2 november
Utrecht
Reparaties van het hart
Dutch Tissue Engineering Congress III
15 november American Heart Association
Anaheim
27 november Cardiovasculaire problematiek
Kerkrade
3 december
Zurich
Cardiac remodeling
12 december Cardiac Hypertrophy and Failure
Munchen
2002
14 februari
Molecularie Cardiologie van hypertrofie
Utrecht
21 februari
De genetica van myocardhypertrofie
Rotterdam
28 februari
Moleculaire Cardiologie. “Gentherapie”
Landgraaf
10 april
Genetic factors in cardiac hypertrophy
Pisa
12 april
Molecular and functional aspects of development
and pathophysiology of the heart
“Stem cell derived cardiomyocytes in mouse and
man”
Amsterdam
24 mei
Moleculaire cardiologie in klinisch perspectief
Tilburg
30 mei
Genetische aspecten van de cardiologie
“Van monogenetische naar polygenetische
cardiovasculaire ziekten”
Maastricht
26 november ACCSAPP
Heeze
e
27 november 4 Mergellandsymposium
Valkenburg
Highlights AHA meeting
Chicago
28 november Moleculaire Cardiologie in de kliniek
UMCU
2003
16 januari
Pathofysiologie Hart en Circulatie, werkgroep ischemie
UMCU
29 januari
Mini workshop PV-loops
UMCU
31 januari
Approach of multigenic disease
Vascular Biology Workshop St. Gerlach
Maastricht
37
18 februari
ECG, cursorisch onderwijs
AZ
Nieuwegein
21 maart
Stamceltherapie bij hartfalen, cursus Vasculaire
Cardiologie
CVOI
Utrecht
3 april
Stem cells for cardiovascular therapy
Ermelo
22 april
Molecular genetics of cardiomyopathies
ICIN, Utrecht
14 mei
Moderator ACCSAP “Molecular Cardiology”
Akkrum
16 mei
15e Internistendagen 2003
Maastricht
27 mei
Pols (Programma Opinion LeaderS) bijeenkomst.
Utrecht
5 juni
Sponsorbijeenkomst Prof. R.L.J. van Ruyvenstichting;
Stamcelontwikkeling en transplantatie.
Utrecht
PHD course “Cardiac Function and Adaption”(5022):
Clinical aspects and Stem cell/ gene therapy.
Papendal
3 oktober
4 oktober
International college of surgeons
Stamcellen in cardiovasculaire aandoeningen
Tilburg
16 oktober
European Meeting on Molecular Diagnostics
Scheveningen
28 oktober
Stagemarkt jaar 6 CRU ’99
Utrecht
30 oktober
Moderator ACCSAP “Moleculaire cardiologie”
Utrecht
3 november
VAT het VAT symposium The golden goal
Optimal treatment of the metabolic syndrome
Utrecht
Symposium Tissue Engineering
Ede
7 november
25 november Seminair Sponsorwerving Prof. R.L.J. van
Ruyvenstichting.
Utrecht
26 november Lunchpraatje Update in Cardiology; Heart failure:
new concepts and approaches
Utrecht
12 december XVIth Annual Scientific WCN Meeting
Innovations in cardiology and clinical implications
Amsterdam
12 december Exploring the limits of cardiovascular interventions
a 30-year journey
Zeist
38
2004
7 januari
The Young Ones, Mico Awards
13 februari
2 Dutch German molecular cardiology meeting
Maastricht
5 februari
Stagemarkt Studentenwetenschapsdag UMCU.
Utrecht
15 maart
ACCSAP cursus “Moleculaire Cardiologie”
Apeldoorn
29 maart
XXV Portuguese Congress of Cardiology
Portugal
20 april
Informatiebijeenkomst Hartezorg,
Hartpatiënten vereniging regio Utrecht.
Utrecht
22/3 april
Jubileum congres NVVC
Amsterdam
13 mei
Symposium van de Nederlandse Vereniging voor
Vaatchirurgie
Veldhoven
14 mei
Het Tilburg Cardiologie Symposium “Diagnostiek
en behandeling van hartfalen anno 2004”
Oisterwijk
17 mei
Symposium Medical Physiology 2004
Utrecht
3 juni
1e Stichts Symposium
Utrecht
14 juni
Moleculaire Cardiologie III
Nieuwegein
16 juni
Hooglerarenbijeenkomst UMCU
Utrecht
Utrecht
nd
30 september Stamcellen bij hart- en vaatziekten: panacee met
potentie?
Enschede
7 oktober
Symposium “Veranderingen in het hart van Meander”.
Amersfoort
8 oktober
Het Eerste Nationale Cardiovasculaire
Lagerhuisdebat
Amsterdam
9 oktober
Nascholingsdag Federatie van Nederlandse
Trombosediensten
Amsterdam
12 oktober
COEUR Course 8 Heart Failure Research
Rotterdam
3 november
Wetenschappelijke vergadering van de
Nederlandse Vereniging van Anesthesiologie
Utrecht
5 november
Nieuwe ontwikkelingen in de Vasculaire
Geneeskunde
Scheveningen
16 november Antihypertensive drug therapy in black people
39
Utrecht
A Cochrane Systematic Review (organisatie)
16 december Hart naar de top
Nieuwegein
2005
24 februari
Exclusion or Targetting
Utrecht
8 maart
Sponsorbijeenkomst Prof. R.L.J. van
Ruyvenstichting
Utrecht
15 maart
Pacemakers: indicaties en follow-up
Utrecht
(organisatie)
19 april
Cardiology and Vascular Medicine Update and
Perspective Heart failure “Molecular biology of
heart failure, cardiac- and circulatory adaption.
Rotterdam
11 mei
Informatiebijeenkomst Hartezorg
Hartpatiëntenvereniging regio Utrecht
Utrecht
13 mei
CVOI-symposium “Tour d’horizon”;
“Hartfalen: een genetische aandoening”.
Noordwijk
25 mei
Docent op COIG-voorjaarscursus Moleculaire
Biologie
Amsterdam
31 mei
2e Stichts Symposium
Utrecht
(organisatie)
24 juni
Symposium Hartfalen: de routekaart naar
optimale zorg. “Stamcellen?”
Amsterdam
30 september OCG-symposium
“Dilaterende CMP binnen de familie”
Den Haag
13 oktober
Regionale Refereeravond Mercure Hotel
‘Acute Coronaire Syndromen’
Nieuwegein
14 oktober
Congres Bonn
Sessie over Stamcellen
Bonn
8 november
Consulent op de Cardiologie Carrousel
‘h-FABP-test’
De Bilt
24/25
november
Opleidingscursus interventie de dagelijkse praktijk
‘En nu verder…’
Zeist
25/26
november
Pfizer Young Cardiovascular Master Class
Oegstgeest
‘State of the art’ en ‘Stamcellen en cardiovascular herstel’
40
28 november Medtronic Avondsymposium
‘Innovatie in de behandeling van hartfalen:
van wetenschap naar de dagelijkse praktijk’.
Utrecht
15/16
december
Regenerative Physiology
Stem cell therapy: hype or hope?
Papendal
2006
13/14
januari
Eugene Heart Start Up Meeting
Gottingen
25-28
januari
Winter Research Meeting 2006
‘Heterogeneity of genetic cardiomyopathies’
Germany
15 maart
Landelijke Moderator ACC TeleReview 2006
Netherlands
11 april
Vergadering ZonMw Commissie
DoelmatigheidsOnderzoek
Utrecht
28 april
Maastricht Symposium on Vascular and Interventional
Cardiology ”Cell transplantation”
Maastricht
11 mei
Als rector tijdens de 3 oraties van de ICIN hoogleraren
J.W. Jukema, W.J. van der Giessen en Y.M. Pinto
Utrecht
11 mei
6 Tilburg Cardiologie Symposium 11 en 12 mei
“Diner discussiant; moleculaire cardiologie voor de
algemene cardioloog”
Oisterwijk
12 mei
PAO-H nascholing voor huisartsen-cardiologiehet hart van uw werk “Hoe ver zijn we met
stamcellen voor het hart?”
Utrecht
e
17 en 23 mei Deelname aan Statistische begrippen in de
medische literatuur
Utrecht
29 mei
e
Voorzitter 3 Stichts Cardiologie Symposium
Utrecht
7 juni
Organisatie en inleiding “Academic Innovations in
Atheroslerosis
Zeist
8 juni
Huisartsen Symposium Cardiologie
Spijk
29 juni
Post AESH symposium nav 21st annual meeting
th
of the American Society of Hypertension and 16
European meeting on Hypertension “Cardiogenetica
bij hartfalen”
Utrecht
21 oktober
Kennisflis @ wetenweek 2006 / Erfocentrum
Utrecht
41
“Stamcellen voor hart- en vaatziekten”
7 november
Organisatie nascholing “Koers in de gezondheidszorg”
Utrecht
9 november
Cardiogenetica avonden
“Moleculair genetisch onderzoek bij hypertrofische
cardiomyopathie: wanneer wel, wanneer niet?”
Venlo
21/22
november
Second HLCU Symposium on Translational Medicine
“Cardiovascular disease: multidisciplinary approaches
for multifactorial diseases”
Zeist
24/25
november
Pfizer Young Cardiovascular Master Class
“Heeft screening zin? Gerichte opsporing met SNPs –
het SMART-cohort”
Oegstgeest
7 december
Seminar ANWB “Plotse dood”
Utrecht
Cardiogenetica avond
“Moleculair genetisch onderzoek bij hypertrofische
cardiomyopathie: wanneer wel, wanneer niet?”
Spreker
Zwolle
1 maart
Van Ruyvenstichting/Rotary De Bilt-Bilthoven
“Stamcellen voor hartreparatie”
Spreker
De Bilt
11 mei
Symposium voor neurologen en cardiologen
“Nieuwe ontwikkelingen op het raakvlak cardiologie
en neurogie”
Spreker
Garderen
15 mei
“Een rondje om het hart”
Spreker
Utrecht
6 juni
Symposium Acadamic innovations in Cardiac Imaging
“Hart en vaten inbeeld”
Organizer
Zeist
6 – 9 juni
International Student Congress of Medical Sciences
Spreker
UMC
Groningen
9 – 12 juni
Heart Failure Congress 2007
Hamburg
5 en 6
oktober
Medclass STOA nascholing
Spreker
Rijswijk
10 oktober
Het derde cardiorenale symposium “The heart and kidney, Amersfoort
2007
11 januari
42
fatal twins” Spreker
30 november Symposium ‘Heart Failure: Link monitoring to Care’
Medtronic Trading NL BV
Voorzitter en spreker
2008
4 maart
Natuurwetenschappelijk Gezelschap Wageningen
Lezing “Stamcellen en hun rol in de geneeskunde”
Spreker
Amsterdam
Wageningen
7 maart
Symposium “Combined stapled coronary bypass and PCI Utrecht
towards least invasive revascularization
8 april
Cardiogenetica Avond
“Cardiogenetische aspecten bij HCM en ARVC”
Spreker
Breda
14 mei
Bijeenkomst “Primaire PCI, het protocol voor de
toekomst”
Emmen
26 mei
Cardiogenetica Avond
“Cardiogenetische aspecten bij HCM en ARVC”
Rotterdam
7 oktober
Cardiogenetica Avond
“Cardiogenetische aspecten bij HCM en ARVC”
Amsterdam
Bijscholing Cardiologie/CCU
“Erfelijkheid bij hart- en vaatziekten”
Utrecht
31 maart
Bijscholing Cardiologie/CCU
“Erfelijkheid bij hart- en vaatziekten”
Utrecht
2 april
Regenerative Medicine Symposium
Utrecht
3 april
Voorjaarscongres NVVC
Amsterdam
23 april
Symposium “Veilig en dichtbij” t.g.v. opening Percutane
Coronaire Interventie Jeroen Bosch Ziekenhuis
Spreker
Helvoirt
28 mei
PAOKC-cursus
“Laboratoriumonderzoek bij hartziekten”
Utrecht
10 juni
Cardiogenetica avond
Genetische aspecten bij bicuspide aortaklep en/of
Venlo
2009
24 maart
43
gedilateerde aorta ascendens. 2. Lamine A/C mutaties
Spreker
30 augustus Cardiogenetica avond
“van klachten gerichte geneeskunde naar voorspellende
geneeskunst: wordt de dokter een waarzegger?”
Barcelona
6 oktober
Spreker Nascholing Cardiogenetica avond
Rotterdam
9 oktober
Cardiovascular Grand rounds Maastricht
“Stemcells: from laboratory to clinic”
Spreker
Maastricht
23 oktober
Lustrumsymposium ‘Trombose en de toekomst’,
voordracht: ‘Stamceltherapie in de cardiologie
Amsterdam
24 november Cardiogenetica avond, cardiogenetische aspecten bij
bicuspide aortaklep en/of gedilateerde aortawortel cq
aorta ascendens
Spreker
2010
27 maart
Zwolle
Biomedisch Interfacultair Congres, hoofdspreker
Leiden
Symposium State of the art cardiovasculair,
Customized genetics
Tilburg
22 mei
Tour d’Horizon, Artificiële weefsels
Noordwijk
7 juni
St. Odulphuslyceum
Nieuwste ontwikkelingen in het stamcelonderzoek
Tilburg
Cardiogenetica avond
Casus: Genetisch risico op coronarialijden en genetische
risicostratificatie
Utrecht
Clinical Investigator Science Symposium (CISS)
Cardiac repair using stem cells
Maastricht
22 april
30 juni
2 juli
16 september Cardiogenetica avond
Casus: Genetisch risico op coronarialijden en genetische
risicostratificatie
Thorn
6 oktober
8 oktober
Cardiogenetica avond
Casus: Genetisch risico op coronarialijden en
genetische risicostratificatie
Apeldoorn
Nationale Patiëntendagen 2010
Stamcellen
Amsterdam
44
9 oktober
Open dag UMC Utrecht
Stamcellen om het hart te repareren
25 november Seminar Procesverbetering en Sturing
Newlands Consultancy Group
Zorgverlening vanuit het perspectief van de client
2011
20 mei
Utrecht
Utrecht
Medische Carriéredag MSFU “Sams”
Utrecht
27 juni
Academic innovations in cardiac imaging
(organisator)
Zeist
30 juni
Workshop Renal Denervation
(organisator)
Houten
Patient Event Medtronic
Heerlen
2012
6 januari
e
25-26 mei
12 Tour d’Horizon
“Stamcellen in de patiënt”
Noordwijk
6 juni
Afscheidscollege prof. R.N.W. Hauer
“Uitzicht op inzicht in het ogenschijnlijk normale hart”
Utrecht
15 juni
CAG symposium
Casussen hartteambespreking
Utrecht
17 september BMM/TeRM annual meeting
presentation and poster award Imaging and Screening
Ermelo
2013
24 april
Cardiovascular Epidemiology course
“Stem cells in clinical practice”
Utrecht
25 april
Regenerative Medicine and Technology
“In stappen van stamcel naar tissue engineering om het
hart te repareren”
Utrecht
17 mei
UMC Utrecht Huisartsendag ‘Samen voor een betere zorg’ Utrecht
“Dokter, ik heb pijn op de borst”
15 juli
Utrecht Summer School Course: Regenerative Medicine
“Clinical application”
45
Utrecht
2014
4 februari
20 maart
Rotary Club Oosterbeek Kabeljouw
“Innovaties in de Cardiologie”
th
VieCuri, 10 Themeday “Diagnostische coronair
angriografie
“Toekomst van de Cardiologie”
46
Renkum
Venlo
CHAIRMAN
1998 &1999
"Cardiobiochemie & moleculaire biologie", Najaarsvergadering NVVC 1998, Garderen, The
Netherlands
“Cardiomyopathies, International Society for Heart Research meeting 1999, Maastricht, The
Nederlands
“Diagnostiek & Pathologie”, Najaarsvergadering NVVC 1999, Garderen, The Netherlands
“Animal models”, 1st US-European e-meeting 1999, Paris, France
2000
“Sudden Cardiac Death”, 2000 Future of Arrhythmology, Lessons from the Past, Promises for
Tomorrow, Maastricht, The Netherlands
“Oxidative stress: a sign of injury or a signal for adaptive processes?”, XXIInd Congress of the
European Society of Cardiology, 2000, Amsterdam, The Netherlands
“W.G. on Cellular Biology of the Heart towards cellular transplantation”, 2000, Stockholm,
Sweden
2001
“Elektrofysiologie”. Voorjaarscongres 2001 NVVC, 2001, Scheveningen, The Netherlands
Clinical Symposium II “Initiating therapy in heart failure”, Vaalsbroek, The Netherlands
2002
“Tour d’horizon”, 2002, CVOI, Noordwijk, The Netherlands
ESC 2002 Session: Growth factor regulation of cardiac size, Berlin, The Netherlands
AHA 2002, Session: Ischemic injury and functional recovery: Metabolism, Function, Ischemia,
Chicago, USA
2003
“Presence and therapeutic potential of stem cells in coronary artery disease” and “Cell cycle
proteins: a future target for the treatment of heart failure. ESC congres 2003, Vienna, Austria
2004
“Estrogen derivatives in cardiovascular disease-old questions, new answers” ISHR 2004
Brisbane, Australia
“Cardiac repair: can we make new cardiomyocytes?” ESC 2004, Munich, Germany
“Experimental cell transplantation: preclinal and clinical developments” ESC 2004, Munich,
Germany
2005
ESC Congress 2005, Stockholm, Sweden
2006
Second Leiden Cardiology Course “The Failing Left Ventricle”, January 16-17, 2006
Heart Failure 2006, June 17-20, “Prevention of heart failure by manipulating maladaptive
hypertrophy”, Helsinki, Finland
ESC World Congress of Cardiology 2006 “Stem cell therapy-the practical approach”,
September 2-6, 2006, Barcelona, Spain
Second HLCU symposium on Translational Medicine; Cardiovascular disease:
multidisciplinary approaches for multifactorial diseases. November 21-22, 2006, Zeist, The
Netherlands
“Symposium on Heart Failure” Cardiology Summit, October 6-8, 2006, Mumbai, India
2007
5th Dutch-German Joint Meeting of Molecular Cardiology Froups “Arrhythmogenesis” February
8-10, 2007, Wuerzburg, Germany
Cardiology and Vascular Medicine Update and Perspective, May 7-9, 2007, Rotterdam
47
Advanced Heart Failure, October 5, 2007, Utrecht
4e Stichts Symposium, May 23 2007, Utrecht
2008
Heart Failure Association Winter Research Meeting Chairman Postersession, January 24,
2008, Garmisch-Partenkirchen, Germany
ACC TeleReview 2008, April 2, 2008, Nieuwegein, Utrecht
Progress in cardiac and vascular tissue engineering”, “Novel aspects in cardiovascular signal
transduction”, “Clinically relevant basic and genetic aspects of arrhythmias. ESC 2008,
Munchen, Germany
2009
HFA Winter Research Meeting 2009, January 28-31, Les Diablerets, Switzerland
-
-
Algemene Ledenvergadering NVVC, Stamceltherapie, April 3, 2009, Amsterdam, The
Netherlands
ESC Congres, August 30 – September 1, 2009 Barcelona, Spain
New therapeutic targets in heart failure , Cell recruitment in cardiovascular repair: Sess.Title:
Cell transplantation for myocardial regeneration
EUGeneHeart Task 2 meeting, “Evaluation of candidate genes as susceptibility genes for
LVH and cardiac failure in man” September 15, 2009, Frankfurt, Germany
2010
Interventional Cardiology 2010, March 7-12, 2010, Microtissues to Repair the heart,
Colorado, USA
FEAM conference, March 25, 2010, morning session 2, Bucharest, Romenia
7e Stichts Cardiologie Symposium, May 17, 2010, “Coagulation Hazard in Atrial Disease”
Utrecht, The Netherlands
ESC Congres, Heart Failure, May 29 – June1, 2010, Chairman: State of the art: genomics in
heart failure research, Berlin, Germany
Symposium, Born to Bike? Cardiologie in de (top)sport, June 9, 2010, Utrecht, The
Netherlands
Frontiers in Cardiovascular Biology, ESC, 16-19 July 2010, Berlin, Germany. Chairman:
Ursula Ravens: Commitment to the heart; Chairman: New opportunities in stem cell research;
Chairman poster session
ESC Congress, August 28 – September 1, 2010, Stockholm, Sweden. Chairman:
Understanding and optimizing cardiovascular repair; Stem cells: new insights, new outcomes
Cardiac repair: Myth or reality?, CVOI, October 1, 2010, Chairman: Clinical Trials, Utrecht,
The Netherlands
No Limits 2010, Symposium Cardiologie & Sport, September 17, 2010, Zeist, The
Netherlands
Symposium Cardiovascular genetics in clinical practice: When and how?, December 15,
2010, Utrecht, The Netherlands, Chairman: Cardiovascular Disease
2011
Netherlands Heart Days 2011, January 27-29, Curaçao, Netherlands Antilles. Chairman:
session Hypertension; Chairman: session Coronary Physiology
th
9 Dutch-German Joint Meeting of the Molecular Cardiology Working Groups, April 14-16,
Ulm, Günzburg. Chairman: Cardiac Repair – what is the answer
8e Stichts Cardiologie Symposium, May 30, 2011, Curing Hypertension, Utrecht, The
Netherlands
ESC Heart Failure 2011, May 21-24, Gothenburg, Sweden. Chairman: New drug targets in
heart failure – from EUGeneHeart.
48
-
2012
2013
-
2014
-
EHRA Europace 2011, June 26-29, Madrid, Spain. Chairman: Mechanism (Basic Science
Arrhythmias, Electrophysiological aspect in stem cell therapy.
Cardiomyocyte Regeneration and Protection, June 20-21, 2011, La Jolla, California, USA.
Chairman: Cellular replacement
Symposium on microRNAs in Cardiovascular Disease, June 30, 2011, Maastricht, The
Netherlands. Chairman: microRNA in heart disease
Conference on the CIED patient perspective, November 4-5, 2011, Tilburg, The Netherlands.
Chairman : Specialized cardiac rehabilitation for ICD patients
ESC Congress 2011, August 27-31, 2011, Paris, France. Chairman: Myocardial regeneration:
searching for the magic key
Symposium Innate Immunity and Cardiovascular Disease, September 5, 2011, Utrecht, The
Netherlands. Chairman: morning session
Symposium Steunhart, een alternatief voor Harttransplantatie? September 14, 2011 Utrecht,
The Netherlands. Chairman: morning session
International Conference on the CIED patient perspective: 'Living in a Device World: Focus on
Recent Challenges and Tools to Improve Clinical Care for Patients with an Implantable
Cardioverter Defibrillator', November 3-4, 2011, Tilburg, The Netherlands. Chairman:
Specialized cardiac rehabilitation for ICD patients.
EuroPCR, May 15-18, 2012, Paris, France. Chairman: Building a simplicity renal denervation
practice
th
10 World Congress or the International Society for adaptive medicine, June 7-10, 2012,
Bucharest, Romania. Session: Cardiac stem cells
rd
3 Lugano Stem Cell Meeting, June 25-26, 2012, Lugano, Switzerland. Chairman: Pracrine
Session
ESC Congress 2012, August 25-28, 2012, Munich, Germany. Chairman: Myocardial
regeneration: what cell sources to use?
Cardiogenetica onderwijs, December 14, 2012, Utrecht, The Netherlands. Chairman: Debat:
De cardiogeneticapoli, wie, wat en hoe?
2nd Utrecht Stem Cell Conference, June 11 , 2013 Utrecht, The Netherlands, Chairman:
Practical aspects of cell therapy in patients
Veiligheid en (hart)chirurgie, June 14, 2013, Utrecht, The Netherlands. Chairman session
Vision and discussion
ESC Congress 2013, August 31 – September 4, 2013, Amsterdam, The Netherlands.
Chairman session Stem cells: unlocking the keys and Renal denervation: beyond the
treatment of resistant hypertension?
48th Annual Scientific Meeting of ESCI, April 30 – May 3, Utrecht, The Netherlands. Chairman
session: Plenary focus session Multidisciplinary view of Regenerative Medicine
49
PUBLICATIONS
INTERNATIONAL
See addendum, Publications Doevendans
DUTCH JOURNALS (not listed in pubmed)
1.
Doevendans PA, Cheriex E, van der Zee R, van den Dool A, van Doorn DJ, de Swart H,
2.
Wellens HJ: Risk stratification in the thrombolytic era: results of a prospective study.
Cardiologie 1996;3:319-323.
3.
Doevendans PA.: Scientific conference on the molecular biology of the normal, hypertrophied
and failing heart. Cardiologie 1997;4:29-30.
4.
Doevendans PA. Evidence-based medicine: cardioprotective strategies to improve outcome
(22 August 1998, Vienna). Cardiologie 1998;5(suppl.):6-7.
5.
Conrath CE, Jongbloed RJ, van Langen IM, van Tintelen JP, Hauer RN, Robles de Medina
EO, Duren DR, Hoorntje TM, Lubbers LJ, Doevendans PA, Mannens MMAM, Geelen JL,
Smeets HJ, Wilde AA: Gene-specific distribution of cardiac events in LQTS1 and LGTS2.
Cardiologie 1999;6:254-259
6.
Doevendans PA: Meeting on Cardiovascular Genomics (10-12 January 1999, Orlando).
Cardiologie 1999;6:219-221.
7.
van Eickels M, Doevendans PA. Scientific conference on molecular, cellular, and integrated
physiological approaches to the failing heart. Cardiologie 1999;11:570-572.
8.
Doevendans PA. Hot line I: results of new clinical trials. Cardiologie 1999;11(suppl.2):4-5.
9.
Doevendans PA. The genetics of fibrillation (editorial). Cardiologie 2000;7:1-2.
10.
Doevendans PA. Molecular medicine at UCSD/SALK (San Diego, 21 March 2000).
Cardiologie 2000;7/8:290-292.
11.
Kirchhoff S, Hofstra L, Smeets JLRM, Doevendans PA. Developments in molecular
cardiology: gene expression in relation to pathophysiology. Cardiologie 2000;7:12-16.
12.
Doevendans PA, Evolving strategies in cardiovascular care: the benefits of renin angiotensin
system blockade. ESC Cardiologie 2000; 7:46-747.
13.
Doevendans PA, Van Empel V, Spiering W, Van der Zee R. Clinical Perspectives of Molecular
Cardiology. Ned. Tijdschr. Klin. Chem. 2001; 26:48-51.
14.
Doevendans PA, Mummery C. Pluripotent Stem Cells: Biology and Applications. Neth Heart J
2001; 2:103-107.
15.
Doevendans PA, van Suylen RJ, van Aarnhem EE, Geskes GG. Fatal rupture of an aneurysm
aneurysm of the left sinus of valsalva into the pericardium. Neth Heart J 2001;9:346-348.
50
16.
Doevendans PA, Cardiovascular hormone replacement therapy: is there a benefit for the risk.
Neth Heart J 2001:9: S11-12.
17.
Sonnemans DG, De Windt L, de Muinck EM, Doevendans PA. Methods in molecular
cardiology: protein analysis. Neth Heart J. 2002;10:181-188.
18.
De Theije CC, de Windt L, Doevendans PA. Methods in molecular cardiology. DNA
sequencing. Neth Heart J 2002; 10:136-144
19.
Sonnemans DGP, de Windt L, de Muinck E, Doevendans PA. Methods in Molecular
Cardiology (3): The Polymerase Chain Reaction. Neth Heart J. 2002; 10:412-418
20.
Doevendans PA, Mummery CL. The days of molecular medicine. Neth Heart J. 2002; 10:387390.
21.
Verduyn SC, Winckels SKG, Gorgels APM, Doevendans PA, Vos MA, Should class III drugs
be initiated in hospital to prevent drug induced Torsade de Pointes arrhythmias? Neth Heart J
2003; 11:70-76
22.
De Theije C, de Windt LJ, Doevendans PA. Methods in molecular cardiology: proteome
analysis. Neth Heart J. 2003; 11: 77-83.
23.
Van den Bosch B, Doevendans PA, Smeets HJM. Methods in molecular cardiology:
microarray technology. Neth Heart J. 2003; 11: 213-220.
24.
Doevendans PA, Genetic secrets from the heart revealed through the zebrafish. Neth Heart J,
2003:11: 243-244
25.
Wehrens XHT, Doevendans PA, Congenital and drug-induced long-QT syndrome: an update.
Neth Heart J, 2004:12: 165-172
26.
Stella PR, Jaegere de P, Batterman JJ, Bouma P, Moerland MA, Doevendans PA. BEta
versus Gamma Utrecht Trial-Cypher (BEGUT-CYPHER) Is intracoronary brachytherapy still
superior to drug-eluting stents? Neth Heart J, 2004:12:389-393.
27.
Passier R, Doevendans PA, Methods in molecular cardiology: in silico cloning. Neth Heart J,
2004:12:400-403
28.
Doevendans PA, From INSIGHT to ACTION-signposting the future of calcium antagonists in
cardiovascular medicine. Neth Heart J, 2004:12:supl 2:33-34.
29.
Jongbloed RJE, Smeets H, Doevendans PA, Van den Wijngaard A, Methods in molecular
cardiology:DHPLC mutation detection analysis. Neth Heart J,2005:vol.13:1:11-17.
30.
Goumans M-J, Doevendans PA, Atsma D, Mummery C. Somatic stem cells and cardiac
repair: where is the science? editorial Neth Heart J Vol.12.No.12.12.2004.
31.
Wieman R, Beelen D, Van der Zwaan C, Lahpor J, De Vos AM, Doevendans PA. Adolescent
with occluded left main coronary artery. Neth Heart J Vol.13.No.6.June 2005.
51
32.
Entius MM, Groenewegen A, Pronk A, Van der Smagt JJ, Loh P, Hauer RN, Derksen R, Van
Gelder IC, Lok DJA, Doevendans PA. Molecular genetic analysis of six Dutch families with
atrial fibrillation. Neth Heart J Vol.13.No.7/8.August 2005.
33.
Doevendans PA, de Man F, Stella PR. Interventional cardiology in the Netherlands. Neth
Heart J (2005)13(11)385-386.
34.
Eefting, F.D., Cramer, M.J.M. ,Stella, P.R., Rensing, B.J. & Doevendans, P.A.F.M. (2006).
Rationale of the PEPARATOR study. A randomised trial with serial cardiac MRI follow-up
testing the ability of atorvastatin to reduce reperfusion damage after primary PCI for acute MI.
Netherlands Heart Journal, 14(3), 95-99.
35.
Kirkels, J.H., Jonge, N. de, Klöpping, C., Lahpor, J.R., Herwerden, L.A. van, Balk, A.H.M.M.,
Bogers, A.J.J.C, Maat, A.P.W.M. & Doevendans, P.A.F.M. (2006). Heart transplantation in
the Netherlands: quo vadis? Netherlands Heart Journal, 14, 425-430.
36.
Man, F.H.A.F. de, Stella, P.R.& Doevendans, P.A.F.M. (2006). Drug-eluting stents not for all
patients. Netherlands Heart Journal, 14, 174-176.
After 2007 NHJ international recognition.
DUTCH LANGUAGE
1.
Doevendans PA, Cheriex E: Een patiente met collaps, waar rook is...!. Hartbulletin
1995;26:202/204-206.
2.
Prins A, Tibben A, Doevendans P: Presymptomatisch genetisch onderzoek bij kinderen met
een risico voor familiaire hypertrofische cardiomyopathie?. Hartbulletin 1996;27:110/113-115.
3.
Doevendans PA: De pathofysiologie van hypertrofische cardiomyopathie. Ned Tijdschr
Geneeskd 1997;141:59-60.
4.
Doevendans PA, Bronsaer R, Bär FWHM, Meijer H. Moleculaire cardiologie: wetenschappelijk
onderzoek en patiëntenzorg. Hartbulletin 1997;28:81-83.
5.
Bronsaer RJP, Doevendans PA. Keukenzout in het hart: chloor. Hartbulletin 1997;28:149-152.
6.
Bronsaer RJP, Doevendans PA. Keukenzout in het hart: natrium. Hartbulletin 1997; 28:11822.
7.
Bronsaer RJP, Geelen J, Vos MA, Doevendans PA. Kalium in het hart: tomaten of bananen?
Hartbulletin 1998;29:22-29.
8.
Bronsaer RJP, de Windt LJ, Doevendans PA. Calcium in het hart: boter, kaas en eieren.
Hartbulletin 1998;29:62-65.
9.
Winkens M, Doevendans PA. Een grensgeval. Hartbulletin 1998;29:27-29.
52
10.
Wilde AAM, van Langen I, Mannens MMAM, Smeets B, Doevendans P. Hypertrofische
cardiomyopathie: bij wie en waarom genetisch onderzoek. Cardiologie 1998;9:489-491.
11.
Doevendans PA. 'In silico cloning' van het T-type-calciumkanaal. Ned Tijdschr Geneeskd
1998;142:2114.
12.
Wilde AAM, van Langen I, Mannens MMAM, Doevendans PA, van Veldhuisen DJ, van
Tintelen JP, Smeets H. Hypertrofische cardiomyopathie; bij wie en waarom genetisch
onderzoek. Tijdschrift voor Cardiologie 1999;1/2:1-4.
13.
Doevendans PA. Het 'ABC' van de Tangier ziekte. Ned Tijdschr Geneeskd 2000; 144: 1456.
14.
Doevendans PA. Is er een genetische oorzaak voor boezemfibrilleren? Cardiologen
vademecum 2001;2:1-2
15.
Boersma HH et al. 99mTc-annexine V bij hartziekten.Pharmaceutisch Weekblad 2001; 136:
106-111.
16.
Wehrens XH, Doevendans PA, Primaire osteomyelitis van het sternum. Ned. Tijdschrift
Geneesk. 2001; 145:245-6.
17.
Doevendans PA, de Windt L, van der Zee MC. Het humane genoom en de betekenis voor
cardiovasculaire ontwikkelingen. Cardiodidact 2001;11-7.
18.
Doevendans PA, Het humaan genoom project. Klinische Cardiologie 2001:1;32-34.
19.
Doevendans PA, Hormonale substitutie-therapie. Wegen de cardiovasculaire voordelen op
tegen de risico’s? Tijdschr Cardiol 2001; 8: 301-3.
20.
Doevendans PA, Myocardinegen speelt sleutelrol bij vorming van hartspier. Ned Tijdschr
Geneeskd 2002;146: 335-336.
21.
Marcelis CL, Schrander-Stumpel CT, Doevendans PA, de Nijs Bik H. Klinische Genetica (32):
familiale hypertrofische cardiomyopathie. Patient Care 2002, 69-74
22.
Stamcellen voor weefselherstel: Onderzoek naar therapie met somatische en embryonale
stamcellen. Gezondheidsraad. 2002
23.
Doevendans PA. Fusie met stamcellen als verklaring voor dedifferentiatie. Ned Tijdschr
Geneesk. 2002; 146: 1204
24.
Doevendans PA, Wat is de verklaring voor hartkloppingen ’s avonds bij het naar bed gaan en
op linker zij draaien bij postmenopauzale vrouwen? Vademecum 2003; 21 nr. 15 – 08 april
25.
Doevendans PA, Het OVERTURE-onderzoek: omapatrilaat versus enalapril bij hartfalen: Ned
Tijdschr Geneesk 2003; 147(13); 629-30
26.
Hassink RJ, Grosfeld MJ, Marcelis C, Delhaas T, Doevendans PA. Hypertrofische
cardiomyopathie: van diagnostiek naar preventie? Ned Tijdschr Geneesk 2003;147:1181-
53
1184.
27.
Doevendans PA, Familiar boezemfibrilleren door een mutatie in een kalium kanaal Ned
Tijdschr Geneesk 2003; 147(28); 1382.
28.
Doevendans PA, Stamcellen verbeteren de doorbloeding van het hart na een recent infarct
Ned Tijdschr Geneesk 2003; 147(40); 1985.
29.
Pronk ACB, Doevendans PA, Welke patiënten moeten door de perifeer cardioloog worden
doorgestuurd voor genetische counseling? Cardiologen Vademecum 2004.
30.
Nathoe HM, Doevendans PA. [The polypill: optimal strategy for reduction of cardiovascular
disease] Ned Tijdschr Geneeskd. 2005 Jul 30;149(31):1740.
31.
Meijs, M.F.L., Vos, A.M. de, Rutten, A., Prokop, M., Cramer, M.J.M, Doevendans, P.A.F.M.
European Congress of Radiology 2005: progress in nonivasive coronary artery imaging using
multislice CT. Netherlands Heart Journal, 13, 2005
32.
Meijs MFL, de Man FHAF, Cramer MJM, Doevendans PA, Prokop M, Stella PR, Multimodality
coronary artery imaging in a high-risk patient. Netherlands Heart Journal, 14,6, june 2006
33.
Bongartz LG, Cramer MJM, Doevendans PA, Braam B, Het cardiorenaal syndroom; “Een
problem in hart en nieren”. Hart Bulletin Feb 2007;38; nr.1;3-10.
BOOK CHAPTERS
1.
Doevendans PA, Hunter JJ, Lembo G, Wollert KC, Chien KR: Strategies for studying
cardiovascular diseases in transgenic mice and gene-targeted mice, in Monastersky GM,
Robl JM (eds): Strategies in transgenic animal science. Washington, American Society For
Microbiology, 1995, pp 107-144.
2.
Kubalak SW, Doevendans PA, Rockman HA, Hunter JJ, Tanaka N, Ross Jj, Chien KR:
Molecular anaysis of cardiac muscle diseases based on mouse genetics, in Adolph KW (ed):
Methods in molecular genetics. Orlando, Academic Press, 1996, pp 470-487.
3.
Doevendans PA, van Dantzig JM, Meijer H, Schaap C. Molecular genetics of human
cardiomyopathies. In: Peters R, Piek J (eds): Molecular cardiology in clinical perspective. 1
Ed. Amsterdam: Knoll, 1997: 33-53.
4.
Doevendans PA, Bronsaer R, van der Zee R, van Eickels M. Molecular cardiology in clinical
perspective. In: Cardiologia Invasiva. Atti del XVI Corso di Emodinamica e Cineangiografia,
Baveno 20-21 novembre 1998.
5.
Doevendans PA, Bronsaer R, Ruiz-Lozano P, van Dantzig J, van Bilsen M. Expression of the
atrial regulatory myosin light chain gene in ventricular cardiomyocytes. In: Doevendans PA,
Reneman R, van Bilsen M (eds): Cardiovascular specific gene expression. Dordrecht, Kluwer
Academic Publishers, 1999.
6.
van Dantzig J, Bronsaer R, Doevendans PA. Myocardial hypertrophy and failure: a molecular
54
approach. In: van der Wall EE, van der Laarse A, Pluim BM, Bruschke AVG (eds): Left
ventricular hypertrophy. Dordrecht, Kluwer Academic Publishers, 1999.
7.
Doevendans PA, van Gilst WH, van der Laarse A, van Bilsen M. Molecular cardiology. Part 1:
Gene transcription in the cardiovascular system. In: Doevendans PA, Molecular Cardiology.
Heusden, Mediselect, 1999, pp5-21
8.
van der Laarse A, Ruwhof C, van Wamel JET, van Gilst WH, Doevendans PA, van Bilsen M.
Molecular cardiology. Part 2: Molecular aspects of cardiac hypertrophy and heart failure.
Mediselect 1999, pp 22-33
9.
de Muinck ED, van Gilst W, van der Laarse A, Doevendans PA. Molecular Cardiology part III:
Restenosis. In: Doevendans PA, Molecular Cardiology. Heusden, Mediselect, 1999, pp34-48
10.
Cornelussen RNM, Snoecks LHEH, Doevendans PA. Molecular Cardiology. Part 4: The role
of inducible stress proteins in the preservation of myocardial function following ischaemia. In:
Doevendans PA, Molecular Cardiology. Heusden, Mediselect, 1999, pp49-67.
11.
Hofstra L, de Muinck E, Doevendans PA. Molecular Cardiology. Part 7: Apoptosis in the
cardiovascular system. In: Doevendans PA, Molecular Cardiology. Heusden, Mediselect,
1999, pp 104-114
12.
Palmen M, van der Zee R, Daemen MJAP, de Muinck ED, Lucassen AJN, Doevendans PA.
Molecular Cardiology. Part 6: Cardiac angiogenesis and growth factors. In: Doevendans PA,
Molecular Cardiology. Heusden, Mediselect, 1999, pp 88-103.
13.
de Windt LJ, Wilde AAM, Doevendans PA. Molecular cardiology. Part 5: Animal models in
molecular cardiovascular research. In: Doevendans PA, Molecular Cardiology. Heusden,
Mediselect, 1999, 68-87.
14.
Bekkers SCAM, Doevendans PA, van der Zee MC. Molecular Cardiology. Part 8: Nitric oxide.
In: Doevendans PA, Molecular Cardiology. Heusden, Mediselect, 1999, pp 115-123.
15.
van Bilsen M, Doevendans PA, Reneman RS, van der Vusse GJ. Molecular Cardiology. Part
9: Metabolic remodelling of the hypertrophied and failing heart. In: Doevendans PA, Molecular
Cardiology. Heusden, Mediselect, 1999, 126-142.
16.
Doevendans PA: Molecular Cardiology. Part 10: Implementation of molecular cardiology into
clinical cardiology. In: Doevendans PA, Molecular Cardiology. Heusden, Mediselect, 1999, pp
143-158.
17.
Carrier L, Jongbloed RJ, Smeets HJ, Doevendans PA. Hypertrophic Cardiomyopathy. In:
Doevendans PA, Wilde AA, editors. Cardiovascular genetics for clincians. Dordrecht: Kluwer,
2001, pp 139-155.
18.
Marcelis C, Doevendans PA, Bonne G. Dilated Cardiomyopathy. In: Doevendans PA, Wilde
AA, editors. Cardiovascular genetics for clincians. Dordrecht: Kluwer, 2001, pp 155-168.
19.
Groothuis S, Van Pol P, Lencer N, Stappers J, Jans J, Janssen J, Dassen W, Doevendans
55
PA, Baljon M, Hasman A, Van Merode, GG. Discrete Event Simulation to support Capacity
Planning for Heart Failure Patients. Computers in Cardiology 2001; 28:137-140.
20.
Dassen W, Spiering W, de Leeuw P, Smits P, Dijk WA, Spruijt H, Gommer E, Bonnemayer C,
Doevendans PA. Unravelling Gene Interactions to Find the Cause of Atherosclerosis, a
Multigenic Disease, Using an Artificial Neural Network. Comp in Cardiol 2001; Vol 28: 373376.
21.
Doevendans PA, Wilde AA. Moleculaire cardiologie. In: Wellens HJ, Roelandt J, editors.
Nederlands Leerboek der cardiologie. Houten: Bohn Scheltema & Holkema, 2002, pp 31-40.
22.
Wilde AA, Langen I, Doevendans PA. Genetica van aandoeningen van de hartspier. In:
Wellens HJ, Roelandt J, editors. Nederlands Leerboek der Cardiologie. Houten: Bohn,
Scheltema & Holkema, 2002, pp . 59-64
23.
Bueno EF, van Rooij E, Lips D, Doevendans PA, de Windt L. Cardiac hypertrophic signaling:
the Good, the Bad and the Ugly. In: Doevendans PA, Kääb S, editors. Cardiovascular
Genomics: new insights into pathophysiology. Dordrecht: Kluwer, 2002, pp 131-155.
24.
Mummery C, Ward D, van den Brink CE, Bird S, Doevendans PA, Tertoolen L, van der
Heyden M, Pera M. Towards embryonic stem cell derived cardiomyocytes. In: Doevendans
PA, Kääb S, editors. Cardiovascular genomics: new pathophysiological concepts. Dordrecht:
Kluwer, 2002, pp 231-243.
25.
van den Bosch B, Doevendans PA, Lips D, Geurts JMW, Smeets B. Towards elucidation of
genetic pathways in cardiac hypertrophy: technique to develop microarrays. In: Doevendans
PA, Kääb S, editors. Cardiovascular genomics: new insights in pathophysiology. Dordrecht:
Kluwer, 2002, pp 97-105.
26.
Doevendans PA, Chien KR, Mummery C. Towards Stem Cell Therapy. In: Chien KR, editor.
The Molecular Basis of Cardiovascular Disease. Philadelphia: Saunders, 2004 107-122.
27.
De Windt LJ, Doevendans PA. Fatty acid homeostatis as a modulator of cardiac disease.
2003, Recent Res. Devel. Biophy. Biochem. ISBN 81-271-0014-5.
28.
De Windt LJ, Doevendans PA, Chien KR. Generation of Genetically Midified Animals. In
Chien KR, editor. The Molecular Basis of Cardiovascular Disease. Philadelphia: Saunders,
2004 49-71.
29.
Doevendans PA, Kirkels JH. Cardiomyopathie, myocarditis en pericarditis.Praktische
huisartsgeneeskunde; Cardiologie. Prins/Verheugt (red) 2005 125-140.
30.
Marcelis CLM, Schrander-Stumpel CTRM, Doevendans PAFM, De Nijs Bik H. Familiale
hypertrofische cardiomyopathie. Praktische Huisartsgeneeskunde; Klinische genetica. Bohn
Stafleu van Loghum 2005 199-207.
31.
Goumans MJ, Smits AvVP, Post S, Hassink RJ, Stella P, Doevendans PA: Can somatic stem
cells regenerate myocardial tissue?, in Pasterkamp G, De Kleijn DP (eds): Cardiovascular
Research: New Technologies, Methods & Applications. New York, Springer, 2005, pp 157-
56
166
32.
Hassink, R.J., Goumans, M.J., Smits, A., Post, S., Vliet, P. van, Doevendans, P.A.F.M.
(2005). Exclusion or Targeting? In N.M. van. Hemel (Ed.), Stem Cells or Reinitiating the Cell
Cycle for Cardiac Repair (pp. 265-276).
33.
Lips DJ, Hassink RJ, De la Riviere A, Doevendans PA. The use of Genetically Modified Mice
in the Investigation of Cardiac Remodeling (2006), (pp. 159-187) in Cardiac Remodeling van
Barry Greenberg.
34.
Conrath CE, Doevendans PAFM. Palpitaties en collaps (2007), (pp. 331-339) in
Probleemgeoriënteerd denken in de cardiologie van Dr. G.K. Hovingh en Dr. G.A. Somsen.
35.
Doevendans P.A.F.M., Hoseyni Guyomi S. Ischemische hartziekten (2010), (pp. 23-41) in
Cardiovasculaire ziektebeelden, de introductie, onder redactie van dr. C. Klöpping
36.
Doevendans P.A.F.M., Kirkels, J.H. Reeks Praktische huisartsgeneeskunde, Cardiologie
(2013), (p135-151) , Cardiomyopathie, myocarditis en pericarditis. Onder redactie van dr. J.C.
Bakx, prof. dr. F.W.A. Verheugt, dr. J.W. Deckers
ISBN 978 90 313 902 74
BOOK REVIEWS
1.
Hoit B.D., Walsh R.A. Cardiovascular physiology in the genetically engineered mouse.
Cardiologie, jaargang 6, p. 471.
2.
Swynghedauw B. Molecular cardiology for the cardiologist. Cardiologie 2000;7:44.
3.
Sanders M.R., Kostis J.B. Molecular cardiology in clinical practice. Cardiologie 2000;4:164.
4.
Sanders M.R., Kostis J.B. Molecular cardiology in clinical practice. Journal de Cardiologie
2000;2:70-71.
5.
Hoit B.D., Walsh R.A. Cardiovascular physiology in the genetically engineered mouse. Neth
Heart J 2002; 10: 488-489.
6.
Ostadal B, Nagano M, Dhalla N.S., Cardiac Development, Neth. Heart. J., 2005;10;380.
BOOKS
1.
Doevendans PA. Cardiac specific gene expression of the regulatory myosin light chains.
(Thesis) December 12, 1997. (ISBN 90 5278 2350)
2.
Doevendans PA, Willems F. Wijzers in de Cardiologie, ed1, Amsterdam, Excerpta Medica,
1998. (ISBN 902198892)
3.
Doevendans PA, Willems F. Dutch pioneers in Cardiology, ed1, Amsterdam, Excerpta
Medica, 1998. (ISBN 902198901 8)
57
4.
Doevendans PA, Reneman R, van Bilsen M. Cardiovascular specific gene expression.
Dordrecht, Kluwer Academic Publishers, 1999. (ISBN 0-7923-5633-0)
5.
Doevendans PA. Molecular Cardiology. Heusden, Mediselect, 1999. (ISBN 90-74764-18-5)
6.
Smeets J.L.R.M., Doevendans PA, Josephson M.E., Kirchhof Ch., Vos M.A. Professor Hein
J.J. Wellens: 33 Years of Cardiology and Arrhythmology. Dordrecht, Kluwer Academic
Publishers, 2000. (ISBN 0-7923-6209-8)
7.
Doevendans PA, Wilde AA, editors. 2001. Cardiovascular Genetics for clinicians. Dordrecht,
Kluwer. (ISBN 1-4020-0097-9).
8.
Doevendans PA, Kääb S, editors. 2002. Cardiovascular Genomics: new pathophysiological
concepts. Dordrecht, Kluwer. (ISBN 1-4020-7022-5)
9.
Wellens HJ, Gorgels A, Doevendans PA. The electrocardiogram in acute myocardial
infarction. 2002, Kluwer. (ISBN 1-4020-7214-7)
10.
Baars, van der Smagt, Doevendans, eds, 2010. Clinical Cardiogenitics (ISBN 978-1-84996470-8)
11.
van der Wall, EE, Bruschke AV, Doevendans PA, van Hemel NM, eds, 2014. Canon van de
cardiologie. Haarlem, dchg medische communicatie (ISBN 978-94-90826-32-1)
58

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