Erik Scherder.pptx

15-‐04-‐14 Normale situatie
Pijn bij dementie
Prefrontale
cortex
PAG
Lc coeruleus
Subst nigra
Ncl parabrach
Prof. dr. Erik Scherder Afdeling Klinische Neuropsychologie, Vrije Universiteit, Amsterdam Thalamus
A Delta and C fibers:
PIJN!
Normale situatie
Prefrontale
cortex
PAG
Lc coeruleus
Subst nigra
Ncl parabrach
Thalamus
Remming van pijn
Remming
(impuls controle)
Remming van negatieve emoties
Remming
(impuls controle)
Remming van negatieve emoties
Remming
(impuls controle)
Remming van de stress as
1 15-‐04-‐14 Normale situaHe PAG
Lc coeruleus
Subst nigra
Ncl parabrach
Thalamus
Remming van negatieve emoties
A Delta and C fibers
Remming van de stress as
Remming
(impuls controle)
Remming van pijn
8 Vasculaire demenHe Centrale neuropathische pijn A Delta and C fibers
9 Vasculaire demen.e Normale situatie
Remming
dlpfc
Remming
dlpfc vlpfc vlpfc
PAG
PAG 2 15-‐04-‐14 Normale situatie
Initiatief
nemen
sm prm pm
Vroeg stadium Alzheimer
S1
sp
smg
ag
Initiatief
nemen
dlpfc
= childhood
= adolescence
= adulthood
= medial
S1
sp
dlpfc
vlpfc
sgg
orb
sm prm pm
stg
phg
erc
atp
itg
h
smg
vlpfc
vac
= sup long fasc
= unc fasc
sgg
orb
= childhood
= adolescence
= adulthood
= medial
ag
stg
phg
erc
atp
itg
h
vac
= sup long fasc
= unc fasc
= no studies
= degeneration
= overactivity
3 15-‐04-‐14 Vroeg stadium AD
Initiatief
nemen
sm prm pm
S1
sp
dlpfc
smg
vlpfc
sgg
orb
Stress beschadigt hippocampus
= childhood
= adolescence
= adulthood
= medial
ag
stg
phg
vac
h
erc
atp
itg
= sup long fasc
= unc fasc
= no studies
= degeneration
= overactivity
Activatie van de stress as
Eind stadium AD
Initiatief
nemen
sm prm pm
S1
sp
dlpfc
smg
vlpfc
phg
sgg
orb
h
= childhood
erc
= adolescence
atp
= adulthood
itg
= medial
ag
stg
vac
= sup long fasc
= unc fasc
= no studies
= degeneration
= overactivity
Remming
(impuls controle)
Bewegen,
muziek,
empathie
Dank voor uw aandacht! 4

Download Report