IGF (suppress) (suppress) IFN P4 Fas L (synergistic) TNF TNF-R Prostaglandins Fas (?) (?) P4-R Sphingomyelin/ceramide pathways MAPK PL-A2 Caspases NFkB JNK AA Bcl-2 (active) Survival Bcl-2 (inactive) Apoptosis
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