Workshops Current trends in Biomedicine THE NUCLEAR LAMINA IN HEALTH AND DISEASE Speakers Organized by: Vicente Andrés Laboratory of Molecular and Genetic Cardiovascular Pathophysiology, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC). Madrid, Spain. Vicente Andrés Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC). Madrid, Spain. Peter Askjaer Andalusian Center for Developmental Biology (CABD), CSIC/Junta de Andalucía/Universidad Pablo de Olavide. Sevilla, Spain. Wendy A. Bickmore MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh. Edinburgh, UK. Scope The human cell nucleus is a highly organized and compartmentalized structure. The nuclear lamina is one of the major structural elements and organizers of the cell nucleus. Besides its well established architectural role, groundbreaking work over the last few years has demonstrated that the lamina and the associated nuclear envelope proteins regulate multiple cellular functions, including higher-order chromatin organization, DNA replication and repair, gene transcription, and signal transduction. Interest in the nuclear lamina has taken on added relevance in recent years with the discovery that mutations in the lamin proteins which make up the lamina, or genetic defects leading to changes in lamin abundance or post-translational processing, cause a variety of rare genetic disorders termed laminopathies. This workshop will bring together leaders in nuclear lamina research with the aim of discussing cutting-edge research in the field which is providing a fertile ground for discoveries that are impacting the basic understanding of cellular functions, aging and disease. Format of the Workshop The workshop will bring together 17 speakers and a maximum of 33-35 participants, to form a group of around 50 people. The scientific programme will start in the morning of Monday, November 16th, and will end around noon on Wednesday, November 18th. Ample time for informal discussion will be reserved. Participants will be invited to present a poster. Venue of the Workshop The workshop will be held in Baeza, at the “Campus Antonio Machado”, a XVII century building turned into a Conference Centre of the Universidad Internacional de Andalucía (UNIA). This Seat includes a recently restored residence, where participants will be accommodated. Baeza is a World Historic Heritage town, renowned for its Renaissance and Gothic buildings. Gisèle Bonne Center of Research in Myology, Sorbonne Universités, UPMC Université Paris 06, INSERM U974, CNRS FRE3617, Institut de Myologie. Paris, France. Peter Askjaer Andalusian Center for Developmental Biology (CABD), CSIC/Junta de Andalucía/ Universidad Pablo de Olavide. Sevilla, Spain. Tom Misteli National Cancer Institute, National Institutes of Health (NIH). Bethesda, USA. Sponsors: Dennis E. Discher Molecular and Cell Biophysics Laboratory, Department of Chemical and Biomolecular Engineering / Graduate Groups in Physics and Cell & Molecular Biology; University of Pennsylvania. Philadelphia, PA, USA. Roland Foisner Max F. Perutz Laboratories, Department of Medical Biochemistry, Medical University Vienna. Vienna, Austria. Susana Gonzalo Department of Biochemistry and Molecular Biology, St. Louis University School of Medicine. St. Louis, MO, USA. Martin W. Hetzer Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies. La Jolla, CA, USA. Juan Carlos Izpisúa Belmonte Gene Expression Laboratory, Salk Institute for Biological Studies. La Jolla, CA, USA. Jan Lammerding Department of Biomedical Engineering, Weill Institute for Cell and Molecular Biology, Cornell University. Ithaca, NY, USA. Carlos López-Otín Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología del Principado de Asturias, IUOPA, Universidad de Oviedo. Oviedo, Spain. Tom Misteli National Cancer Institute, National Institutes of Health (NIH). Bethesda, MD, USA. Baeza, Spain • 16th-18th November 2015 Deadline: th 18 September 2015 Venue: Campus Antonio Machado Universidad Internacional de Andalucía Palacio de Jabalquinto Plaza de Santa Cruz, s/n 23440 Baeza (Jaén), Spain Tel: +34 953 74 27 75 Fax: +34 953 74 29 75 E-mail: [email protected] Eric C. Schirmer The Wellcome Trust Centre for Cell Biology and Institute of Cell Biology, University of Edinburgh. Edinburgh, UK. More information and application: Catherine M. Shanahan BHF Centre, Cardiovascular Division, King’s College London. London, UK. [email protected] Colin L. Stewart Developmental and Regenerative Biology, Institute of Medical Biology / Department of Biological Sciences, NUS. Singapore. Bas van Steensel Division of Gene Regulation, Netherlands Cancer Institute. Amsterdam, The Netherlands. Katherine L. Wilson Department of Cell Biology, Johns Hopkins University School of Medicine. Baltimore, MD, USA. http://www.unia.es/biomedicine
© Copyright 2025 ExpyDoc