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CONFERENCE PROGRAMME
SUNDAY MARCH 2ND - WARM-UP
1700
Registration open
Poster hanging
1800 - 1900
Birgit LANE, Institute of Medical Biology, A*STAR, Singapore:
Introducing the Skin Research Institute of Singapore
1900 - 2100
WELCOME RECEPTION
Infuzi restaurant, Chromos, Biopolis
MONDAY 3RD MARCH - DAY 1
0800
Registration desk opens
0830 - 0900
WELCOME – OPENING SPEECHES
0900 – 0945
LIM Chuan Poh
Chairman of A*STAR
Birgit LANE
Executive Director, Institute of Medical Biology,
Singapore
BRITISH HIGH COMMISSION KEYNOTE LECTURE
Fiona WATT, King’s College London, UK:
Dermal fibroblast heterogeneity
0945 – 1015
Break
1015 – 1230
SKIN STEM CELLS AND AGEING
1015 – 1045 Yann BARRANDON, École Polytechnique Fédérale de Lausanne and
Institute of Medical Biology, A*STAR:
Epithelial stem cells and skin morphogenesis
1045 – 1115 Pritinder KAUR, Peter MacCallum Cancer Centre, Australia:
The secret lives of pericytes in tumour growth and metastasis
1115 – 1130 Xinhong LIM, Institute of Medical Biology, A*STAR, Singapore:
Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling
1130 – 1200 Petra BOUKAMP, German Cancer Research Centre, Germany:
Long-term culture of scaffold-dependent skin models: the niche determines
stem cell maintenance and function
1200 – 1215 Priscilla PEH, National University of Singapore:
Stem cell-bioactive scaffold tissue engineering approach to skin
regeneration in a full thickness skin wound
1215 – 1230 Oliver DREESEN, Institute of Medical Biology, A*STAR, Singapore:
The contrasting roles of lamin B1 in ageing and human disease
MONDAY 3RD MARCH - DAY 1
1230 - 1400
LUNCH AND POSTER VIEWING
1400 – 1700
WOUND HEALING AND BARRIER REPAIR
1400 – 1430 Marjana TOMIC-CANIC, University of Miami, USA:
Molecular Biology and Pathology of Wound Healing
1430 – 1500 Prabha SAMPATH, Institute of Medical Biology, A*STAR, Singapore:
A defective molecular switch impedes healing of chronic wounds
1500 – 1530 David BECKER, LKC School of Medicine, NTU, Singapore:
Connexins as a novel target in wound healing
1530 – 1600 Break
1600 – 1630 Katsuto TAMAI, Osaka University, Japan:
Cross-talk mechanism between injured skin and bone marrow: application
for regenerative medicine for intractable skin diseases
1630 – 1645 Matthew HARDMAN, University of Manchester, UK:
A novel role for PKC alpha in regulating dermal architecture and skin
integrity
1645 – 1700 Clare GARCIN, University of Manchester, UK:
A novel role for Edar signalling in wound healing
1800 - 2000
CONFERENCE GET-TOGETHER (food and drink)
Immunos Building, Biopolis
TUESDAY 4TH MARCH - DAY 2
0900 – 1230
SKIN DISEASES, MODELS, CANCER AND THERAPEUTIC SOLUTIONS
0900 – 0930 John McGRATH, King's College London, UK:
Developing new cell therapies for inherited skin diseases
0930 – 1000 BRITISH HIGH COMMISSION SPONSORED LECTURER
Richard GUY, University of Bath, UK:
Optimisation and quantification of topical drug delivery to the skin
1000 – 1030 Break
1030 – 1100 Pierre COULOMBE, Johns Hopkins University, Baltimore, USA:
A novel role for keratin in regulating gene expression in tumor-prone
keratinocytes
1100 – 1130 Birgit LANE, Institute of Medical Biology, A*STAR, Singapore:
Keratinocyte models of epidermolysis bullosa linking wound healing,
stress and cancer
1130 – 1145 Tjinta BRINKHUIZEN, GROW, Maastricht Univ. Medical Centre,
Netherlands:
Functional epigenomics of basal cell carcinoma suggests new
treatment options
1145 – 1200 Kim ROBINSON, University of Dundee, Scotland, UK:
RNAi depletion of PRSS21 in cutaneous squamous cell carcinoma
keratinocytes induces maspin dependent apoptosis
1200 – 1230 Erwin TSCHACHLER, Medical University of Vienna, Austria:
The role of autophagy in the biology of keratinocytes and melanocytes
1230 - 1400
LUNCH AND POSTER VIEWING
1230 - 1330
LUNCH DISCUSSION: Working with Industry
TUESDAY 4TH MARCH - DAY 2
1400 – 1715
MORE THAN EPIDERMIS: HAIR FOLLICLES AND SKIN APPENDAGES
1400 – 1430
1430 – 1500 Ralf PAUS, University of Manchester, UK:
Exploring the controls of human skin mitochondrial biology:
neurohormones to the front
1500 – 1515 Elaine CHEW, Genome Institute of Singapore, A*STAR:
Androgenetic alopecia: analysis of transcriptome differences between
balding and non-balding human dermal papilla cells
1515 – 1530 Jiawei LIU, Legacy Healthcare, Switzerland:
The discovery of a novel topical apoptosis modulator and antiinflammatory agent opens perspectives for the treatment of several
skin disorders
1530 – 1600 Break
1600 – 1630 Kiarash KHOSROTEHRANI, University of Queensland, Australia:
Extrinsic regulation of epidermal homeostasis
1630 – 1700 Maurice van STEENSEL, Maastricht University Medical Centre and
Institute of Medical Biology, A*STAR:
Understanding acne: Insights into a common skin disease from ultrarare genetic disorders
1700-1715
ROUND-UP DISCUSSION
1800 -
Free evening to explore Singapore
WEDNESDAY 5TH MARCH - DAY 3
0900 – 1245
SKIN DIFFERENTIATION AND THE PERFECT BARRIER
0900 – 0930 Terry LECHLER, Duke University, North Carolina, USA:
Ndel1 promotes local keratin assembly at desmosomes
0930 – 0945 Srikala RAGHAVAN, Institute for Stem Cell Biology and Regenerative
Medicine (inStem), NCBS, Bangalore, India:
The Integrin Network: Role of Integrins in Epithelial Homeostasis and
Inflammation
1000 – 1030 Michael CANGKRAMA, Monash University, Australia:
Coordinate regulation of Transglutaminases by the Grainyhead-like
transcription factors is critical for maintenance of skin barrier
function post-natally
1030 – 1100 Break
1030 – 1100 Masayuki AMAGAI, Keio University, Japan:
Epidermal barrier function and its dysfunction in atopic diseases
1100 – 1115 Hyun Jong KIM, Seoul Medical Center Research Institute, S Korea:
The Effect of Novel Cannabinoid Receptor Agonists on the Oxazolone
induced Atopic Dermatitis Mouse Model
1115 – 1130 Bani Kaur SURI, National University of Singapore:
CA6: a novel candidate gene for atopic dermatitis
1130 – 1200 Irwin McLEAN, University of Dundee, Scotland, UK:
Mouse models of keratoderma – disease mechanisms and therapy
development
1200 - 1330
LUNCH AND FINAL POSTER BROWSING
WEDNESDAY 5TH MARCH - DAY 3
1330 – 1700
SKIN DEFENCE MECHANISMS
1330 – 1400 Michael GIVSKOV, Singapore Centre on Environmental Life Sciences
Engineering and University of Copenhagen, Denmark:
Bacterial cell- signaling circuits as targets for biofilm control
1400 – 1430 Artur SCHMIDTCHEN, LKC School of Medicine, NTU, Singapore and
University of Lund, Sweden:
Basic and translational studies of innate immunity
1430 – 1500 Florent GINHOUX, Singapore Immunology Network, A*STAR,
Singapore:
The role of skin dendritic cells in T cell-mediated cutaneous diseases
1500 – 1530 Break
1530 – 1545 Helen WILLIAMS, University of Manchester:
The role of the intracellular receptor Nod2 and skin microflora in
cutaneous wound repair
1545 – 1600 Hongyuan SHEN, Institute of Molecular and Cellular Biology,
A*STAR:
Ikk2 regulates tissue integrity and cytokinesis during zebrafish
development
1600 – 1630 Lai Guan NG, Singapore Immunology Network, A*STAR: Dynamic
imaging of neutrophil responses during immune complex-mediated
inflammation
1630 – 1700 Kenji KABASHIMA, Kyoto University:
Live imaging of the skin and inducible skin associated lymphoid tissue
(iSALT)
1700 – 1710
PRIZEWINNER ANNOUNCEMENTS
1710 - 1730
ROUND-UP DISCUSSION
1730
- END OF CONFERENCE -

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