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Plant Foods for Human Nutrition
June 2011, Volume 66, Issue 2, pp 129-135
Date: 19 Apr 2011
Antigenotoxicity and Antioxidant Activity of Acerola Fruit
(Malpighia glabra L.) at Two Stages of Ripeness
Abstract
Genotoxic and antigenotoxic effects of acerola fruit at two stages of ripeness were investigated using mice
blood cells. The results show that no ripeness stage of acerola extracts presented any genotoxic potential
to damage DNA (Comet assay) or cytotoxicity (MTT assay). When antigenotoxic activity was analyzed,
unripe fruit presented higher DNA protection than ripe fruit (red color) extract. The antioxidant capacity
of substances also showed that unripe samples inhibit the free radical DPPH more significantly than the
ripe ones. The results about determination of compounds made using HPLC showed that unripe acerola
presents higher levels of vitamin C as compared to ripe acerola. Thus, vitamin C and the complex mixture
of nutrients of Malpighia glabra L., and especially its ripeness stages, influenced the interaction of the
fruit extract with the DNA. Acerola is usually consumed when ripe (red fruit), although it is the green
fruit (unripe) that has higher potential as beneficial to DNA, protecting it against oxidative stress.
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Title
Antigenotoxicity and Antioxidant Activity of Acerola Fruit (Malpighia glabra L.) at Two
Stages of Ripeness
Journal
Plant Foods for Human Nutrition
Volume 66, Issue 2 , pp 129-135
Cover Date
2011-06-01
DOI
10.1007/s11130-011-0223-7
Print ISSN
0921-9668
Online ISSN
1573-9104
Publisher
Springer US
Additional Links
Register for Journal Updates
Editorial Board
About This Journal
Manuscript Submission
Topics
Food Science
Chemistry/Food Science, general
Plant Physiology
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Ecology
Nutrition
Keywords
Malpighia glabra L.
Acerola
Genotoxicity
Antigenotoxicity
Vitamin C
Industry Sectors
Pharma
Chemical Manufacturing
Biotechnology
Electronics
IT & Software
Telecommunications
Consumer Packaged Goods
Authors
Roberta da Silva Nunes (1) (2)
Vivian Francília Silva Kahl (1)
Merielen da Silva Sarmento (1)
Marc François Richter (3)
Letícia Veras Costa-Lotufo (4)
Felipe Augusto Rocha Rodrigues (4)
Juan Andres Abin-Carriquiry (5)
Marcela María Martinez (5)
Scharline Ferronatto (6)
Alexandre de Barros Falcão Ferraz (6)
Juliana da Silva (1)
Author Affiliations
1. Laboratório de Genética Toxicológica—Programa de Pós-Graduação em Genética e
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Toxicologia Aplicada, Universidade Luterana do Brasil, 92425–900, Canoas, Rio
Grande do Sul, Brazil
2. Centro Universitário Luterano de Ji-Paraná, Universidade Luterana do Brasil,
76.907–438, Ji-Paraná, RO, Brazil
3. Universidade Estadual do Rio Grande do Sul, UERGS, 90.010–191, Porto Alegre,
RS, Brazil
4. Laboratório de Oncologia Experimental, Universidade Federal do Ceará, UFC,
60341–970, Fortaleza, CE, Brazil
5. Department of Neurochemistry, Instituto de Investigaciones Biológicas Clemente
Estable, 11600, Montevideo, Uruguay
6. Laboratório de Farmacognosia e Fitoquímica, Universidade Luterana do Brasil,
92425–900, Canoas, RS, Brazil
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