Curriculum Vitae (1) Name, Gender, Birth date. / (2) Education. 名 陳韋弘(Male) 姓 Name (in Print) Chen, Wei-Hong Date of Birth 01/02/1978 Year (s) Field of study Education / Training Institution and location Degree Taipei Medical University M.S. Taipei Medical University Ph.D. Taipei Medical University Postdoctoral Stem cell center training 2003 Biomaterials 2008 Tissue Engineering Stem cell biology 2009 (3) Current position and relevant experience Professional and Employment 2008-Present: General Manager, Kooper biotech Co., Ltd. 總經理，固寶生物科技股份有限公司 2008-Present: Research Scientist, Stem Cell Research Center, Taipei Medical University 研究員，台北醫學大學幹細胞研究中心 (4) Fields of specialty Biomaterials Stem cell biology. Tissue engineering Cartilage regeneration Executing clinical trials (5) Major awards and honors 2009 7th National Innovation Award 國家新創獎 2009 6th Taipei International Symposium for Molecular Imaging Young Investigator Award th 2008 6 National Innovation Award 國家新創獎 2007 4th Taipei International Symposium for Molecular Imaging Young Investigator Award 1 (6) Publications 1. Liu HY, Huang CF, Lin TC, Tsai CY, Tina Chen SY, Liu A, Chen WH, Wei HJ, Wang MF, Williams DF,Deng WP. Delayed animal aging through the recovery of stem cell senescence by platelet rich plasma. Biomaterials. 2014 Dec. (SCI, IF=8.312). 2. Wei HJ, Nickoloff JA, Chen WH, Liu HY, Lo WC, Chang YT, Yang PC, Wu CW, Williams DF, Gelovani JG, Deng WP. FOXF1 mediates mesenchymal stem cell fusion-induced reprogramming of lung cancer cells. Oncotarget. 2014 Oct. (SCI, IF=6.627). 3. Chen WH, Lo WC, Hsu WC, Wei HJ, Liu HY,Lee CH,David F. Williams,Deng WP*.Anabolic Actions of Hyaluronic Acid and Platelet-rich Plasma Synergistically Promotes Articular Cartilage Regeneration for Osteoarthritis Therapy. Biomaterials. 2014. (SCI, IF=8.312). 4. Liu HY, Liu MC, Wang MF, Chen WH, Tsai CY, Wu KH, Zeng R, Deng WP*. Potential osteoporosis Recovery by Deep Sea Water through Bone Regeneration in SAMP8 mice. Evid Based Complement Alternat Med. 2013 (SCI, IF=2.175). 5. Liu MC, Chen WH, Wu LC, Hsu WC, Lo WC, Yeh SD, Wang MF, Zeng R, Deng WP*. Establishment of a Promising Human Nucleus Pulposus Cell Line for Intervertebral Disc Tissue Engineering. Tissue Engineering. 2013, May; (SCI, IF=4.254). 6. Chen WH, *Lo WC, Lin TC, Hwang SM, Zeng R, Hsu WC, Chiang YM, Liu MC, David F. Williams, Deng WP*. Preferential Therapy for Osteoarthritis by Cord Blood MSCs through Regulation of Chondrogenic Cytokines. Biomaterials. 2013, Jul; 34(20)4739-48. (SCI, IF=8.312) (*Equal contribution). * 7. Chen WH, Zeng R, Lo WC, Chen SY, Lai TY, David F. Williams, Deng WP*. The role of the ERK1/2 pathway as an alternative to the aging-diminished cyclic AMP pathway in calcitonin-mediated chondrogenesis in human nucleus pulposus. Biomaterials. 2012, Nov; 33(33)8256-64. (SCI, IF=8.312) (*Correspondence). 8. Wu CC, Chen WH, Zao B, Lai PL, Lin TC, Lo HY, Shieh YH, Wu CH, Deng WP*. Regenerative potentials of platelet-rich plasma enhanced by collagen in retrieving pro-inflammatory cytokine-inhibited chondrogenesis. Biomaterials 2011, 32(25):5847-5854. (SCI, IF= 8.312) 9. Chen WH, Lai MT, Wu AT, Wu CC, Gelovani JG, Lin CT, Hung SC, Chiu WT,Deng WP*. In Vitro Stage-specific Chondrogenesis of Mesenchymal Stem Cells Committed to Chondrocytes. Arthritis & Rheumatism. 2009, 60:450-459 (SCI, IF= 7.871). 10. Chen WH, Liu HY, Lo WC, Wu SC, Chi CH, Chang HY, Hsiao SH, Wu CH, 2 Chiu WT, Chen BJ, Deng WP*. Intervertebral Disc Regeneration in an Ex Vivo Culture System using Mesenchymal Stem Cells and Platelet-rich Plasma. Biomaterials. 2009, 30:5523-5533. (SCI, IF=8.312) 11. Lo WC, Hsu CH, Wu AT, Yang LY, Chen WH, Chiu WT, Lai WF, Wu CH, Gelovani JG, Deng WP*. A Novel Cell-Based Therapy for Contusion Spinal Cord Injury Using GDNF-Delivering NIH3T3 Cells with Dual Reporter Genes Monitored by Molecular Imaging. J Nucl Med.2008, 49:1512–1519 (SCI, IF= 5.563). 12. Chen WH, Lo WC, Lee JJ, Su CH, Lin CT, Liu HY, Lin TW, Lin WC, Huang TY, Deng WP*. Tissue-engineered intervertebral disc and chondrogenesis using human nucleus pulposus regulated through TGF-β1 in platelet-rich plasma.J Cell Physiol.2006, 209:744-754. (SCI, IF=3.874) 13. Chen WH, Lai WF, Deng WP*, Yang WK, Lo WC, Wu CC, Yang DM, Lai MT, Lin CT, Lin TW, Yang CB. Tissue engineered cartilage using human articular chondrocytes immortalized by HPV-16 E6 and E7 genes. J Biomed Mater Res A.2006, 76:512-520 (SCI, IF= 2.841) 14. *Hung SC, Deng WP*, Yang WK, Liu RS, Lee CC, Su TC, Lin RJ, Yang DM, Chang CW, Chen WH, Wei HJ, Gelovani JG. Mesenchymal stem cell targeting of microscopic tumors and tumor stroma development monitored by noninvasive in vivo positron emission tomography imaging. Clinical Cancer Research 2005, 11:7749-7756 (SCI, IF=8.193) *S-C Hung and W-P Deng contributed equally to this work 專 (7) Patent 利 名 稱國 別 專利號碼 發 明 人 專利權 期 間 富含血小板血漿衍生之生長因子 中華民國 I 411443 鄧文炳,羅文 固寶生 2013.10.11複合物之製備方法以及於活體外 政,陳韋弘 物科技 2029.02.25 促進一組織生長之方法 METHOD OF PRODUCING PLATELET-RICH PLASMA (PRP) DERIVED GROWTH FACTOR COMPLEX AND METHOD FOR ENHANCING GROWTH OF TISSUE IN VITRO 3 治療計篩檢方法以及椎間盤培養 中華民國 I 453280 鄧文炳,羅文 固寶生 2014.9.21-2 方法 政,陳韋弘 物科技 029.02.25 4
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