HYDROLYSED NUTRIPREM MARCH 2014 HYDROLYSED NUTRIPREM Pack size: Cow & Gate hydrolysed nutriprem is available to hospitals only as a sterilised, ready-to-feed milk in a 90ml plastic bottle. Ingredients: Indications: Cow & Gate hydrolysed nutriprem is a food for special medical purposes, for the dietary management of preterm and low birthweight infants who require hydrolysed protein. Hydrolysed nutriprem contains hydrolysed protein which may be helpful for preterm infants post surgery or who are not tolerating standard preterm formulas. Hydrolysed nutriprem preterm formula has been specially developed and formulated in line with the latest ESPGHAN 2010 recommendations for infants weighing 1-1.8kg1. It contains long chain polyunsaturated fatty acids (AA & DHA) in amounts recommended by experts1, nucleotides, vitamins and minerals to meet the requirements of growing preterm infants, which should reduce the need for additional nutrient supplementation1. Contra-indications: Cow & Gate hydrolysed nutriprem should only be used under the close medical supervision of a neonatologist or dietitian. The levels of most vitamins and minerals in Cow & Gate hydrolysed nutriprem are higher than in infant milks and additional supplements are not usually necessary. This product is not suitable for intravenous use. Demineralised water, Lactose (from milk), Maltodextrin, Vegetable oils (including MCT oil and soya lecithin), Hydrolysed whey protein concentrate (from milk), Casein hydrolysate (from milk), Emulsifier (citric acid ester of mono and diglycerides of fatty acids), Egg lipids, Fish oil, Calcium glycero phosphate, Sodium chloride, Calcium chloride, Vitamin C, Magnesium hydrogen phosphate, Inositol, Sodium hydrogenophosphate, L-tryptophan, Choline chloride, Vitamin E, Iron pyrophosphate, Magnesium chloride, Taurine, Vitamin A, Emulsifier (soya lecithin), Zinc sulphate, Nicotinamide, Cytidine 5-monophosphate, L-carnitine, Vitamin D3, Pantothenic acid, Uridine 5-monophosphate sodium salt, Sodium selenite, Inosine 5-monophosphate sodium salt, Adenosine 5-monophosphate, Folic acid, Biotin, Potassium iodide, Guanosine 5-monophosphate sodium salt, Riboflavin, Thiamin, Copper sulphate, Vitamin B6, Vitamin K1, Vitamin B12, Manganese sulphate. Allergy advice: For allergens, see ingredients in bold. May not be suitable for all vegetarians due to the processing of some ingredients and that it contains LCPs from fish oil. Instructions for use: 1 Cow & Gate hydrolysed nutriprem can be fed to the infant at a rate of between 150–200ml/kg/day, until the infant reaches 1800–2000g. 2 Cow & Gate hydrolysed nutriprem can be used to complement breastmilk, i.e. given as alternate feeds with breastfeeds, or prior to the availability of breastmilk. 3 The hydrolysed nature of this product means the contents will settle, so the bottle needs to be shaken well before use. Now improved, the most complete preterm range available 4 There will be some discolouration over time, this is completely normal and the product is safe to use. 5 Discard bottle and remaining contents within 1 hour of opening. Practical advice for healthcare professionals from Practical advice for healthcare professionals from www.in-practice.co.uk For Healthcare Professional Use Only Important notice Breastfeeding is best for babies. Cow & Gate hydrolysed nutriprem is a food for special medical purposes and should only be used under medical supervision, after full consideration of the feeding options available including breastfeeding. Cow & Gate hydrolysed nutriprem is suitable for use as the sole source of nutrition for preterm and low birthweight infants. This product is for enteral use only. PDS: 1006769 20.01.2014 HCP517 (03/14) Nutrients Units Per 100ml Per 100kcal Major nutrients Energy Protein Nutrients Units Per 100ml Per 100kcal Minerals Fatty Acid Composition g/100g Unsaturated kJ 335 420 Potassium mg 85 106 Palmitoleic acid C16:1(n-7) 0.17 kcal 80 100 Chloride mg 83 103 Oleic acid C18:1(n-9) 45.6 g 2.6 3.3 Calcium mg 104 130 Linoleic acid C18:2(n-6) 12.7 of which whey g 1.3 1.6 Phosphorus mg 58 72.2 Alpha linolenic acid C18:3(n-3) 1.77 of which casein g 1.3 1.6 Magnesium mg 8.1 10.1 Gamma linolenic acid C18:3(n-6) 0.17 Carbohydrate g 8.4 10.5 Iron mg 1.6 2 Eicosaenoic acid C20:1(n-9) 0.41 of which sugars g 4.5 5.6 Zinc mg 1.1 1.4 Dihomo gamma linolenic acid C20:3(n-6) 0.03 of which lactose g 3.9 4.8 Copper µg 80 99.8 Arachidonic acid C20:4(n-6) 0.5 g 4 5.0 Manganese µg 10 12.5 Eicosapentaenoic acid C20:5(n-3) 0.1 g 1.5 1.9 Selenium µg 4.5 5.6 Erucic acid C22:1(n-9) 0.07 of which unsaturates g 2.5 3.1 of which LCPs† Flouride mg ≤0.003 ≤0.005 Docosapentaenoic acid C22:5(n-3) 0.01 mg 39.7 49.5 of which arachidonic acid (AA) mg 19 23.7 Iodine µg 25 31.2 Docosahexaenoic acid C22:6(n-3) 0.39 Nervoic acid C24:1(n-9) 0.05 of which docosahexaenoic acid (DHA) mg 15 18.7 Fat of which saturates Fibre g 0 0 Sodium mg 70 87.1 Vitamins Vitamin A µg-RE Vitamin D3 µg Vitamin E mg α-TE Vitamin K1 µg 6 7.5 Vitamin C mg 17 21.2 325 405 3 3.7 3.5 4.4 Others L-carnitine mg 1.8 2.25 Choline mg 17 21.2 Amino Acid Composition Inositol mg 24 29.9 L-Alanine 4.5 Taurine mg 5.5 6.9 L-Arginine 3.4 Nucleotides mg 3.2 3.99 L-Aspartic acid 6 Osmolarity mOsmol/l 370 L-Cysteine 1.6 Osmolality mOsmol/ kg H2O 405 L-Glutamic acid 10 Potential renal solute load mOsmol/l 245 Thiamin (B1) mg 0.14 0.17 Fatty Acid Composition Riboflavin (B2) mg 0.2 0.25 Saturated Niacin (B3) mg NE 3.2 3.99 Caproic acid C6:0 0.12 Pantothenic acid mg 0.9 1.1 Caprylic acid C8:0 4.11 Vitamin B6 mg 0.12 0.15 Capric acid C10:0 3.20 Folic acid µg 35 43.7 Lauric acid C12:0 8.06 Vitamin B12 µg 0.18 0.22 Myristic acid C14:0 3.50 Biotin µg 3.5 4.4 Palmitic acid C16:0 14.1 Stearic acid C18:0 3.19 Arachidic acid C20:0 0.30 Behenic acid C22:0 0.42 Lignoceric acid C24:0 0.18 †Long Chain Polyunsaturated fatty acids Reference: 1. Agostoni C et al. J Pediatr Gastroenterol Nutr 2010;50:85-91 g/100g LA:ALA 7.2:1 g/100g protein Glycine 1.9 L-Histidine 2.5 L-Isoleucine 6.5 L-Leucine 10.6 L-Lysine 10.1 L-Methionine 2.4 L-Phenylalanine 4 L-Proline 8.2 L-Serine 5.7 L-Threonine 6.2 L-Tryptophan 1.8 L-Tyrosine L-Valine 4 6.7
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