Conference Program

Program Schedule
DNP Satellite Meeting
Monday, Sept 29, 2014, BBAW, Markgrafenstr. 38, 10117 Berlin
09:00
09:10
09:40
10:00
10:20
10:40
11:10
11:40
12:00
12:20
12:40
13:30
14:00
14:20
14:40
15:00
Welcome by Shimon Vega (Rehovot)
DIP - DNP Session 1
Chair: Shimon Vega
Leibniz-Saal
Marina Bennati (Göttingen) Recent Insights in Overhauser DNP in Liquids at 0.3 and 3 Tesla
Umit Akbey (Berlin) DNP of Proteins and Sillicates: New Radicals and Higher Temperatures
Vasyl Denysenkov (Frankfurt/M) Overhauser DNP Experiments on Oriented Lipid Bilayers at
9.4 T: Setup and Applications
Or Szekely (Rehovot) Sensitizing Protein NMR by Nuclear Hyperpolarization Methods
Coffee Break
Jan-Henrik Ardenkjaer-Larsen (Lyngby) Hyperpolarized Metabolic Imaging: Preclinical and
Clinical Progress
Akiva Feintuch (Rehovot) Static and MAS DNP. Similarities and Differences
Daphna Shimon (Rehovot) Hetero-Nuclear Polarization Exchange During DNP
Discussion time
Lunch
DIP - DNP Session 2
Chair: Hartmut Oschkinat
Leibniz-Saal
Geoffrey Bodenhausen (Lausanne) Technical Improvements for Dissolution DNP
Andriy Marko (Frankfurt/M) Role of Dipolar Electron Spin-Spin Interaction in High Field DNP
Experiments in Liquid Solutions
Christian Bretschneider (Rehovot) DNP in Diamond
Discussion time
Internal Discussion of DIP Project Members
Chair: Shimon Vega and Hartmut Oschkinat
FGMR2014
Monday, Sept 29, 2014, BBAW, Markgrafenstr. 38, 10117 Berlin
15:00
Registration
Foyer
BBAW Markgrafenstr. 38
16:30
17:30
Educational Session
Chair:
Leibniz-Saal
Gunnar Jeschke (Zürich) Advanced EPR for
NMR spectroscopists
Shimon Vega (Rehovot) Advanced DNP for
Beginners
18:30
Welcome Mixer & Snacks
19:00
19:10
Welcome / Opening remarks
Presentation of the FGMR-Award
Chair: Christina Thiele and Marina Bennati
Leibniz-Saal
FGMR Honory Member Robert G. Griffin (Cambridge, USA) Overhauser Effects in
Insulating Solids
Presentation of the Ernst-Awards
Chair: Wolfgang Jahnke
Leibniz-Saal
19:30
20:15
20:25
Moritz Schmidt (Konstanz) A Genetically Encoded Spin Label for Electron Paramagnetic
Resonance Distance Measurements
20:45
21:05
Nanette Jarenwattananon (Los Angeles) Thermal Maps of Gases in Heterogeneous
Reactions
David Schulze-Suenninghausen (Karlsruhe) Rapid Heteronuclear Single Quantum
Correlation NMR Spectra at Natural Abundance
Tuesday, Sept 30, 2014, Campus Buch, MDC.C, Robert-Rössle-Str. 10, 13125 Berlin
09:00
09:30
10:00
10.30
11:00
11:30
12:00
12:30
13:30
13:55
14:20
14:35
14:50
15:05
15:20
15:50
16:15
16:40
16:55
Plenary I: Frontiers in Magnetic Resonance
Chair: Jochen Balbach
Axon I
1
13
Lucio Frydman (Rehovot) Emerging Opportunities in High-Sensitivity H and C In Vivo
Magnetic Resonance
Thomas Prisner (Frankfurt a. M.) New Methodical Aspects for Dipolar Spectroscopy
Christian Hilty (College Station) Dissolution DNP in Chemistry
Coffee Break
Plenary II: Imaging
Chair: Bernhard Blümich
Axon I
Peter Jezzard (Oxford) New MRI Methods for Assessment of Cerebrovascular Disease
Jens Frahm (Göttingen) Magnetic Resonance Imaging in Real Time
Klaas Prüssmann (Zürich) Advances in NMR Magnetometry for MRI Applications
Lunch
A1: Materials & Small Molecules
B1: BioMR-Applications
Chair: Christina Thiele
Axon II Chair: Enrica Bordignon
Axon I
Ernst Rössler (Bayreuth) Field-Cycling NMR Jochen Balbach (Halle) Ex vivo NMR during
Relaxometry Investigating Soft Matter
PTH Hormone Phosphorylation and
Alzheimer Amyloid Formation
Eike Brunner (Dresden) Solid-state NMR
Christiane Ritter (Stöckheim) Solid-state
and SENS DNP Studies of Diatom Biosilica
NMR Structure of the Helical Signal
Transduction Filament MAVS
Benno Meier (Southampton) Electric
Aaron Hahn (Berlin) Site-Directed Spin
Detection of Ortho and Para Water in
Labelling of Sulfite Oxidase Using NonFullerene Cages
Natural Amino Acids
Hideto Matsuoka (Bonn) Time-Resolved
Franziska Kappert (Frankfurt) Structural
EPR and DFT Studies of Organic
Characterization of FGFR-Ligand Interaction
Electroluminescent Materials
by NMR Spectroscopy
Ulrich Scheler (Dresden) Interfaces and
Johann Klare (Osnabrück) Conformational
Dynamics in Polymer Composite Materials
Heterogeneity of Roc Domains in WT and
Mutant C. tepidum Roc-COR
Daniel Gunzelmann (Geelong) Decoupled
Manuel Etzkorn (Düsseldorf) NonNa+ ion Conduction in Poly-AMPS Based
Conventional Approaches for the NMR
Ionomer Electrolytes by Solid-State NMR
Characterization of Membrane Proteins
Coffee Break
A2: Signal Enhancement Techniques
B2: NMR in Chem. Biology and Drug
Design
Chair: Marina Bennati
Axon II Chair: Wolfgang Jahnke
Axon I
Anne Lesage (Lyon) Determining the
Gregg Siegal (Leiden) NMR as a Structural
Conformation of Surface Species by DNP
Biology Tool for Drug Discovery – Making a
Enhanced Solid-State NMR
Comeback
Shimon Vega (Rehovot) Indirect Double
Geoffrey Bodenhausen (Paris) Study of
Cross Effect DNP on Heteronuclear Spin
Ligand-Protein Interactions by Combining
Systems
DNP with Long-Lived States
1
13
Björn Corzilius (Frankfurt a. M.) H, C, and Brigitte Fiege (Basel) A Combination of NMR
15
N Direct Solid Effect DNP with Gd(III)
and X-Ray Crystallography Reveals the Fine
Details of Mannoside Binding to FimH Lectin
Stefan Glöggler (UCLA) Hyperpolarisation of Heiko M. Möller (Potsdam) NMR Studies
Unprotected Amino Acid Derivates Utilizing
with the 216 kDa Transmembrane Enzyme
17:10
17:25
18:00
18:30
20:00
PHIP in Water
Chris Witte (Berlin) MRI of Hyper-CEST
Xenon Biosensors Targeted to Cell-Surface
Glycans
+
Complex Na -NQR from V. cholerae
Sonja Dames (Garching) Phosphorylation
Induced Dynamic Changes Facilitate
Estrogen Independent Coactivator Binding to
ERβ
Veronika Kropf (Regensburg) Modulation of
the Conformational Equilibrium of Activated
Ras by Potential Drug Compounds
Roberto Rizzato (Göttingen) Sensitivity
Enhancement in ENDOR by Cross
Polarisation and Relaxation
Poster Session 1 (odd numbers presenting)
Wine and Cheese – Informal Snacks and Drinks, Poster Session continued
FGMR member meeting
Wednesday, Oct 1, 2014, Campus Buch, MDC.C, Robert-Rössle-Str. 10, 13125 Berlin
09:00
09:30
10:00
10:30
11:00
11:25
11:50
12:05
12:20
13:15
13:40
14:05
14:30
14:45
Plenary III: Small Molecules & Materials
Chair: Kay Saalwächter
Axon I
Lyndon Emsley (Lyon) DNP Enhanced Solid-State NMR Spectroscopy
Christina Thiele (Darmstadt) Recent Advances in Orienting Organic Compounds for RDC
Structural Analysis
Gerd Buntkowsky (Darmstadt) Applications of Solid State NMR in Heterogeneous Catalysis
Coffee Break
A3: Dynamics and Computational
B3: BioMR applications
Methods
Chair: Steffen Glaser
Axon II Chair: Leif Schröder
Axon I
Kay Saalwächter (Halle) Rotational and
Philipp Selenko (Berlin) Cells, Drugs and
Translational Diffusion in Crowded Protein
NMR
Solutions
1
Thomas Heydenreich (Garching) Obtaining A. Alia (Leiden) In Vivo H MRI and Localized
Insight into Spin Manipulation: TimeSpectroscopic Analysis of Alzheimer's Disease
Frequency Representation of NMR Pulses
in Mouse Models
31
Johannes Weber (Siegen) Linking P
Steffen Goerke (Heidelberg) The Signature of
Magnetic Shielding Tensors to Crystal
Protein Unfolding in CEST Imaging
Structures
Janosch Hennig (Neuherberg) Combining
Daniela Lalli (Florenz) Studying the Ferritin
NMR and Small-Angle Neutron Scattering to Nanocage by NMR
Study Protein-RNA Complexes
Lunch
A4: BioMR – Methods & Apps
B4: Materials & Small Molecules
Chair: Eike Brunner
Axon I Chair: Johannes Liermann
Axon II
Daniella Goldfarb (Rehovot) Probing
Jürgen Senker (Bayreuth) Studying the
Protein Conformation in Cells by EPR
Nucleation of Supramolecular Polymer
3+
Distance Measurements Using Gd Spin
Additives with NMR Crystallography
Labeling
Bernd Reif (Garching) Amyloid Aggregates
Claudia Schmidt (Paderborn) Effects of
and Large Soluble Protein Complexes
Micellization and Aggregrate Growth on the
NMR Spectra of Surfactants
Jörg Matysik (Leipzig) The Solid-State
Bernhard Blümich (Aachen) Compact NMR:
Photo-CIDNP Effect
Non-Destructive Testing and Real-Time
Spectroscopy
1
Müge Kasanmascheff (Freiburg) Insights
Maryia Sin (Dresden) Quantitative H
into the FeMo Cofactor of Nitrogenase
Spectroscopy in Studies of Liquid-Phase
Adsorption on Porous Materials
Garima Jaipuria (Göttingen) The 18 kDa
Philipp Selter (Münster) Synthesis and
Translocator Protein in a Lipid Bilayer
Characterization of PAS-PPO Co-Polymers for
+
Li Batteries
15:00
Wiktor Kozminski (Warschau) New High
Dimensionality Experiments for Intrinsically
Disordered Proteins
Alicia Lund (Santa Barbara) Directly Probing
27
Surface Al in Al-SBA-15 with Static and MAS
DNP
15:15
Dmitry Akhmetzyanov (Frankfurt a. M.)
2+
PELDOR on High Spin Mn Coupled with a
Nitroxide Radical
15:30
Rasmus Linser (Göttingen) Ultra-SparseNUS, Diagonal-Compensated 4D
Spectroscopy for Facilitated Structure
Determination
Coffee Break
16:00
16:45
17:30
18:15
Plenary IV: Public Lectures
Chair: Hartmut Oschkinat
Axon I
Mitsu Ikura (Toronto) Systems Biology of Ras Signalling by NMR
Harald Schwalbe (Frankfurt a. M.) NMR in Chemical Biology and Drug Design
John-Dylan Haynes (Berlin) What Does Functional MRI Teach us About the Human Mind?
Poster Session 2 (even numbers presenting)
19:30
20:45
21:15
Barbeque (Poster Session continued)
John Waugh and the Early Days of CP
Drinks & Dancing
Thursday, Oct 2, 2014, Campus Buch, MDC.C, Robert-Rössle-Str. 10, 13125 Berlin
09:00
09:30
10:00
10:30
11:00
11:30
12.00
12.30
12:40
13:10
Plenary V: Magnetic Resonance in Structural Biology
Chair: Robert Bittl
Axon I
Anja Böckmann (Lyon) Atomic-Resolution 3D Structure of Amyloid β Fibrils Bearing the
Osaka Mutation: Parts I & II
Beat Meier (Zurich) Atomic-Resolution 3D Structure of Amyloid β Fibrils Bearing the Osaka
Mutation: Parts III & IV
Gunnar Jeschke (Zürich) Sensitivity Enhancement in Pulsed EPR on Nitroxide and Gd(III)
Spin Labels
Coffee Break
Plenary VI: Magnetic Resonance in Structural Biology
Chair: Thomas Risse
Axon I
Wayne Hubbell (Los Angeles) Revealing Protein Conformational Substates and Dynamics
with Site-Directed Spin Labeling and High Pressure EPR
Adam Lange (Berlin) Supramolecular Assemblies Studied by 3D and 4D Solid-State NMR
Michael Sattler (Garching) Structure and Dynamics of Protein Complexes Using Integrated
Structural Biology
Concluding remarks Gerd Buntkowsky, Enrica Bordignon, Thomas Risse, Christina Thiele
Lunch (in Campus Mensa)
G-NMR

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