KURA Biotec Brochure 2014

A Beta-glucuronidases catalogue validated for
forensic toxicology, WPDT, TDM and anti-doping.
7,000
6,000
CBD (ng/ml)
CODEINE RECOVERY WITH BG100™
100
80
4,000
EBG
3,000
BG100™
2,000
Helix pomatia
1,000
0
60
40
20
40
60
TIME (MINUTES)
SYNTHETIC CANNABINOIDS
SAMHSA compliant protocol available.
Complete recovery of Oxymorphone, Hydromorphone, Buprenorphine,
Tapentadol, Norbuprenorphine, Morphine at Hi/Lo concentrations in 60
minutes. No 6-MAM formation.
•
•
•
•
Oxazepam
>90%
100%
Lorazepam
>90%
100%
Alprazolam
>90%
100%
400
300
200
100
0
THC RECOVERY
100
EBG
80
BG100™
60
Patella vulgata
Bovine liver
40
Helix pomatia
20
0
3
4
5
6
7
R. RESPONSE
STEROIDS
CANNABINOIDS
80
β-glucuronidase • • •
40
20
BG100™
P. vulgata
Bovine liver H. pomatia 1 H. pomatia 2
Etiocholanolone
DHEA
17α-estradiol
Estrone
All steroids in 60 minutes without conversions.
WADAcompliantprotocolavailable.
aryl-sulfatase •
BAM
Red Abalone β-glucuronidase/Aryl-Sulfatase mix
β-glucuronidase • • •
60
0
Application
Quantification and screening of all known glucuroconjugates.
FORENSIC - WPDT - TDM.
Antidoping-Glucuronidatedsteroids.
Application
Analytes presenting an important sulfate-conjugation.
Steroid-profiling including EPA, DHEA and Antidoping.
Quantification of unknown substances and xenobiotics.
Banned substances in animals.
Dotted line: recovery without hydrolysis.
Room temperature hydrolysis possible. No analyte conversions.
aryl-sulfatase •
BG2.5
Red Abalone
β-glucuronidase Powder
RCS-4 pentanoic
100%
AM2201 hydroxypentyl
at 30 minutes
>90%
% hydrolyzed/
nonhydrolyzed
at 18 minutes
Temazepam
JWH-018 hydroxyindole
500
pH
β-glucuronidase • • •
10timesmoreefficient
Minimizedmatrixeffect
Improveddataquality
Over97%recoveryofJWH-018
SYNTHETIC CANNABINOIDS HYDROLYSIS WITH BG100™
BENZODIAZEPINES
aryl-sulfatase -
Application
Quantification and screening of all known glucuroconjugates.
FORENSIC - WPDT - TDM.
Antidoping-Glucuronidatedsteroids.
Comprehensive hydrolysis of Cannabinoids compounds.
80
JWH-122 hydroxypentyl
20
AM2201 hydroxyindole
0
JWH-210 hydroxyindole
0
β-glucuronidase • • •
BG100™
Red Abalone
β-glucuronidase Solution
2,500
5,000
10,000
ENZYME CONCENTRATION (U/ml)
JWH-250 hydroxyindole
PERCENTAGE
RECOVERY (%)
Application
Labile analytes-hydrolysis at neutral pH/low temperature.
Steroid-glucuronides-WADA-compliant.
Enhanced sensitivity of EIA/online-screening
5,000
OPIOIDS/OPIATES
PERCENTAGE
RECOVERY (%)
EBG
Recombinant E. coli
β-glucuronidase Solution
CBD RECOVERY
Epitestosterone
aryl-sulfatase • •
AS
Red Abalone
Aryl-sulfatase Powder.wder
Application
Quantification of sulfoconjugates.
β-glucuronidase •
aryl-sulfatase • • •
The
β-glucuronidase
Experts
Optimize hydrolysis
Simplify sample workflow
Improve Accuracy
Distributors
CONTACT INFORMATION
www.kurabiotec.com
Sales: [email protected]
Inquiries: [email protected]
Chile (Headquarters)
Gnechen J2
Puerto Varas, Chile
Tel. (+56 9) 82336932
www.chiron.no
USA (Distribution Office)
723 Glasgow Ave., Unit A
Inglewood, CA 90301
Tel. (+1 424) 258 5087

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