Thugs, Bugs and Drugs! David Aucoin DVM, DipACVCP! Chief Technology Officer! VCA ANTECH! Thug! Giardia duadenalis! Giardia in Colorado! ! Reportable Human Disease! ! Is Dog Giardia different from Human Giardia?! ! Where is it?! ! Management Goals! Giardia in Colorado! ! Reportable Human Disease! Reported cases of Human Giardiasis is increasing in Colorado Giardia in Colorado! ! Is Dog Giardia different from Human Giardia?! Giardia in Colorado! ! Is Dog Giardia different from Human Giardia?! Giardia in Colorado! ! Assemblage D is Dog Specific! ! Assemblage F is Cat Specific! ! Assemblage A and B is found in humans! ! Certain Sub-assemblages A/B are considered Human Specific! Giardia in Colorado! ! Asymptomatic Dogs! ! Urban Setting in SouthWest! ! 35-40% of Giardia Positive samples had Human Specific Genotypes! Giardia in Colorado! ! Where is it?! Giardia in Colorado! ! Weld County! Giardia in Colorado! ! Arapahoe County! Giardia in Colorado! ! Denver! Giardia in Colorado! ! Douglas County! Giardia in Colorado! ! Boulder! Giardia in Colorado! ! Management Goals! ! Do I treat when asymptomatic?! ! Is there a Cure?! ! Which is best Drug?! Giardia in Colorado! ! Management Goals! ! Do I treat when asymptomatic?! ! Is there a Cure?! ! Which is best Drug?! Giardia in Colorado! ! Flagyl (metronidazole)! ! GOOD: 70-90% Efficacy at best! ! 50 mg/kg BID x 5 days! Giardia in Colorado! ! Panacur (fenbendazole)! ! BETTER > 90% Efficacy! ! 50 mg/kg OD x 3 days in food! Giardia in Colorado! ! Drontal Plus (febantel/ praziquantel/pyrantel)! ! BEST > 95%! ! Labeled Dose x 2 days! ! If Recurrent: Repeat as Management 3-4 times a year! Thug! Leptospira interrogans! Leptospirosis! Where is it?! How do I test for it?! Should I test for it?! Treatment Options! Leptospirosis in Colorado! ! NOT Reportable Human Disease! ! Is Dog Leptospirosis different from Human?! ! Where is it?! ! Treatment Goals! Leptospirosis in Colorado! ! Where is it?! El Paso County with 1/20th the population as Metro Areas is County with Highest Activity Leptospirosis in Colorado! ! Considered a Mid West Disease! ! Now its Pan-Regional! ! Seasonal: Spring-Summer most common! ! MAT most common test (250 serovars!)! ! Serovars VERY difficult to standardized! ! L.Pomona and L.Grippotyphossa (Hepatic vs Renal?)! ! L.Bratislava and L.autumnalis NOT Infective! When do I consider Leptospirosis! ! Increase in Renal and Liver Function tests! ! Acute: Fever? Vomiting? Petecchia?! Treatment! ! Good news! 80-90% success! ! Better News: Susceptable to simple penicillins! ! Best News: ! ! Doxycycline 10 mg/kg BID x 3-4 weeks! ! Enrofloxacin 5 mg/kg SID x 3 weeks! Questions?!
© Copyright 2024 ExpyDoc
