Company Overview PPI

Company Overview PPI
Speed | Innovation | Happiness
Phama Packaging Innovations
About Bilcare Group

BIL from Bhandari Industries Ltd
Founder Mohan Bhandari

Founded in 1995

Headquarter in Pune, India

USD 500 million in revenues

Over 2,500 customers globally

Bilcare Ltd is listed on Bombay Stock Exchange (BSE)

Team of 1,600 strong professionals

Research-driven customer-centric organization

Comprehensive and innovative product portfolio

Global footprint with 8 manufacturing sites

State-of-the-art research and manufacturing facilities with operations in
Singapore, USA, Germany, Italy and India
Speed | Innovation | Happiness
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Bilcare Solutions
Bilcare Research AG - History
1962
1965
Founded under the
name of Myraplast
Staufen GmbH,
production: 200 tpa
1962
Acquired by
Alusuisse,
(1974
integrated
LONZA)
Name changed
into
Kunststoffwerk
Staufen
1969
Acquisition of plant in
Bötzingen from Pegulan.
Name changed into
Vereinigte
Kunststoffwerke
GmbH,
production: 11.000 tpa
Speed | Innovation | Happiness
1983
Acquired by ICI,
production: 33.000 tpa
1988
Integrated into EVC,
production: 52.000 tpa
1997
2005
Integration of EVC
members Vereinigte
Kunststoffwerke
GmbH and
Mazzucchelli Vinyls
into EVC Rigid Film
Acquisition of
Adriaplast
2004
EVC Films
separated from EVC
Polymer
Acquisition of PVCfilm plant in the USA
Name changed
into INEOS Films
2010
08/10 Bilcare acquired
INEOS Films
12/10 Name Change to
Bilcare Research
INEOS market bid
for 100 % share
equity in EVC
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Bilcare Solutions
Bilcare Research
Bilcare Research AG
is organized in four Business divisions
Speed | Innovation | Happiness
Pharma
Packaging
Innovations
Global supplier to the pharmaceutical industry offering a wide range of
pharmaceutical films & foils, product specific research services.
Packaging
Films
Solutions
Leading supplier of a wide range of rigid mono and multilayer films for
food and non-food consumer goods.
Cards
Solutions
Specialty
Films
Solutions
Core and overlay films for EMV, ID, driver license, inlays,
dual interface, gift and Casino playing cards.
Various specialized mono layered and stentered, films for printing and
decoration, visual packaging, office material, shrink sleeve and technical
applications.
4
Bilcare Solutions
Bilcare Research – Production Plants
■ Weißandt-Gölzau, Germany
Staufen, Germany ■■ Bötzingen, Germany
Castiglione, Italy ■
Delaware, USA ■
■ Nasik, India
Pune, India ■
■ Singapore
Speed | Innovation | Happiness
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Bilcare Solutions
Bilcare Research – Sales 2013
Annual turnover of: Bilcare Research AG, Bilcare Research GmbH, Bilcare Research S.r.l., Bilcare Research Inc.
Speed | Innovation | Happiness
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Bilcare Solutions
Pharma Packaging Innovations
The Global Supplier to the Pharmaceutical Industry
Speed | Innovation | Happiness
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Bilcare Solutions
Bilcare Vision
To be a true value partner for
the global pharmaceutical
sector, addressing its
complete value chain with
innovative and research
driven services & products
Speed | Innovation | Happiness
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Bilcare Solutions
Pharma Packaging Innovations (PPI)
Leading Supplier to the Pharmaceutical Industry
Bötzingen
More than 30 % market share
Delaware
Global representation and distribution network
Nasik
Most comprehensive portfolio in the Industry
Dedicated sales force
Singapore
In-house coating / lamination in class 100 000
5 dedicated Sites
Speed | Innovation | Happiness
Pune
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Bilcare Solutions
PPI - Product Range
Films and foils from low to ultra high barrier materials
for all applications used in
pharmaceutical, medical and healthcare packaging
Speed | Innovation | Happiness
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Bilcare Solutions
PPI - Product Range
Speed | Innovation | Happiness
 Mono
- PVC / PET-G
 Duplex
- PVC/PVDC
 Triplex
- PVC/PE/PVDC
 Aclar®
- PVC/PCTFE

- PVC/PVDC
 CFF
- PVC/Alu/OPA
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Bilcare Solutions
Mono - PVC / PET-G
 Applications:





Pharmaceutical blister packs
Ampoule packs
Syringe packs
Medical device packs
EtO-sterilisation
 Thickness range 60 – 800 mic
 Homopolyer / Copolymer formulations
 Light protection (UV inhibitor, colours)
Speed | Innovation | Happiness
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Bilcare Solutions
Duplex - PVC/PVDC
 Characteristics
 2-layer films PVC/PVDC
 Superior dimensional
stability
 High water vapour and
oxygen barrier
 Excellent processability
 No difference in water vapour
and oxygen transmission
compared to „Triplex“ structures
 Cost effective high barrier film
PVDC Coating 40, 60, 90, 120 g/m²
Standard thickness PVC 200 and 250 µm
Speed | Innovation | Happiness
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Bilcare Solutions
Triplex - PVC/PE/PVDC
 Characteristics
 Good mechanical flexibility of
 3-layer films PVC/PE/PVDC
the film
 Superior dimensional stability
 High water vapour and
oxygen barrier
PVDC Coating 40, 60, 90 g/m²
Intermediate PE layer 25 or 30 µm
Standard thickness PVC 200 and 250 µm
Speed | Innovation | Happiness
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Bilcare Solutions
Aclar® - PVC/PCTFE
 Characteristics
 High water-vapour barrier
 Superior dimensional stability
 Reduced heating
temperatures / higher speed
 Excellent processability
 Chemically stable, biochemically
inert
 Flex-crack resistant
 High transparency
 Excellent layflat
Aclar® 160, 900, 20E, 2000,
3000, 4000, 6000
Special PVC formulation to avoid curling
Standard thickness PVC 200 and 250 µm
®
Speed | Innovation | Happiness
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Product of
Bilcare Solutions
- PVC/PVDC
 Characteristics
 Unique water vapour and
oxygen barriers
 Optimum film flexibility
 Excellent processability
 “Triplex” structures
requirements eliminated
AquaBa 130, 160, 200
Standard thickness PVC 200 and 250 µm
Speed | Innovation | Happiness
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Bilcare Solutions
Cold Form Foil - PVC/Alu/OPA
 Characteristics
 High malleability for deep drawing
blister cavities
 High aesthetic appeal
 100 % barrier against water
vapour, gases, light etc.
 Excellent formability
 Sealable with standard
aluminum foil
OPA 25 µm
Alu 45 and 50 µm
PVC 60 µm
Speed | Innovation | Happiness
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Bilcare Solutions
PPI - The Perfect Film for your Application
Venus
Aclar® 6000
Aqua│Ba® 200
Aclar® 4000
0,04
0,06
0,06
Aqua│Ba® 160
0,08
Aclar® 3000
0,08
Aqua│Ba® 130
Aclar® 2000
Tropical Conditions
ASTM F-1249
38o C / 90 % r.h.
Base Film PVC 250 µm
0,00
0,11
0,11
Aclar® 900
0,24
PVDC 120 g/m²
0,25
Aclar® 20E
0,27
PVDC 90 g/m²
Aclar® 160
PVDC 80 g/m²
PVDC 60 g/m²
PVDC 40 g/m²
0,30
0,35
0,35
0,45
0,65
3,30
PVC Mono
Water Vapour Transmission Rate [g/m2d]
Speed | Innovation | Happiness
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Bilcare Solutions
PPI - The Perfect Film for your Application
Venus
Aqua│Ba® 200
Aqua│Ba® 160
Aqua│Ba® 130
PVDC 120 g/m²
PVDC 90 g/m²
PVDC 80 g/m²
PVDC 60 g/m²
PVDC 40 g/m²
Tropical Conditions
ASTM D-3985
23o C / 50 % r.h.
Base Film PVC 250 µm
0,00
0,07
0,10
0,13
0,30
0,50
0,60
0,70
1,20
Aclar® 6000
9,00
Aclar® 4000
11,30
Aclar® 3000
12,30
Aclar® 2000
13,30
Aclar® 900
14,60
14,80
Aclar® 20E
15,00
Aclar® 160
16,00
PVC Mono
Oxygen Transmission Rate [cm³/m*d]
Speed | Innovation | Happiness
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Bilcare Solutions
PPI in the Pharmaceutical Industry
since 2010
2008
2001
1990‘s
1970‘s
1960‘s
Development
of rigid PVC
films for
blister
packaging
Speed | Innovation | Happiness
PVDC
coating of
PVC-films
40g/m²
■ Triplex
■
Development of
■ PVC/Aclar®
Production of
■ AquaBa®
■ PET-G
Implementation of
■ BilcareOptimaTM
Development of
■ Bilcare Academy
Production of
■ Duplex
90,120 g/m²,
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Bilcare Solutions
PPI - BilcareOptimaTM
Speed | Innovation | Happiness
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Bilcare Solutions
PPI - BilcareOptimaTM
 It is the first and only scientific packaging development study for the
pharmaceutical solid dosage formulations
 Studies and quantifies degradation pattern of the final formulation and
suggests optimal packaging using software based mathematical
modeling
 Reliable tools to decrease time to market and offers the ability to select
the optimal packaging from the beginning
 Precursor to stability study
Speed | Innovation | Happiness
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Bilcare Solutions
PPI – BilcareOptimaTM Methodology

Degradation pattern of formulation is evaluated using a set of designed
experiments

Three fresh batches are studied under various climatic conditions to evaluate








Hygroscopicity
Physical degradation
Chemical degradation
Drug release properties
Hardness & friability
Photo sensitivity
Gas liberation
The blister is designed and thinning profile modeled to predict real-life MVTR
Speed | Innovation | Happiness
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Bilcare Solutions
Speed | Innovation | Happiness
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Bilcare Solutions
What is Bilcare Academy
 Unique competence centre
 Training modules
 Special services
 Solid educational platform for customers and potential customers
 Training modules will address all areas of our customers processes
related to blister packaging
 Packaging development
 Production
 QA / QC
Speed | Innovation | Happiness
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Bilcare Solutions
What is Covered by Bilcare Academy?
Modules:
1.
2.
3.
4.
5.
6.
7.
8.
The diversity of packaging materials and their properties
Select the ideal packaging material for your product and process
Production of PVC films (plant tour)
Typical defects of calendered PVC films and their impact on films and your product
/ process
Design cost effective and effective incoming inspections and create meaningful
specifications
Blister production - Thermoforming parameters and potential issues
TM
BilcareOptima - Packaging solutions that pay off
GMP Standards – Validation of machinery / processes
Special services:
1.
2.
3.
Optimize your production process and reduce the overall cost
Optimize blister design for better protection
TM
BilcareOptima – Packaging solutions that pay off
Speed | Innovation | Happiness
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Bilcare Solutions
Bötzingen - Pharma Production Plant
 Production of mono,
coated/laminated films under one
roof
 Dedicated facility
 314 Employees
 ISO 9001 certified
 ISO 15378 certified
 ISO 14001 certified
 EMAS 1221/2009/EU validated
 Capacity: 40,000 tons
 State of the art equipment
Speed | Innovation | Happiness
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Bilcare Solutions
Bötzingen - State of the Art Machinery
 4 calender-lines
 1 coating line
 1 laminating line
 8 reel slitters
 Automated labelling and
packaging
 In-line surface inspection
Speed | Innovation | Happiness
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Bilcare Solutions
Bötzingen - PVDC Coating Line
 State of the art coating line
 Capacity: 25,000 tons
 In-line inspection
 In-line coating weight controls
 Contact less air-borne dryers
 Vacuum fixed web transport
 Multiple electrostatic web cleaning
 GMP measures
Speed | Innovation | Happiness
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Bilcare Solutions
Bötzingen - Lamination Line
 State of the art lamination line
 Use of solvent free and waterborne
adhesives
 State of the art control and surface
treatment systems
 Integrated processes: QM, GMP, ISO
15378 und ISO 14001
Products:
PVC/PE/PVDC
PVC/PE
PVC/Aclar®
and other Multilayer Structures
Speed | Innovation | Happiness
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Bilcare Solutions
Bötzingen - Reel Slitters
 State of the art slitters
 In-line surface inspection
 Automated labelling
 Automated packaging
Speed | Innovation | Happiness
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Bilcare Solutions
Delaware - Pharma Production Plant
 Production of films and foils
 Pharmaceutical research services
- BilcareOptima™
 110 Employees
 ISO 9001 certified
 Capacity: 18,000 tons
 State of the art equipment
Speed | Innovation | Happiness
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Bilcare Solutions
Nasik - Pharma Production Plant
 Production of mono,
coated/laminated films
under one roof
 Dedicated facility
 200 Employees
 ISO 9001:2008 certified
 Capacity: 14,000 tons
 State of the art equipment
Speed | Innovation | Happiness
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Bilcare Solutions
Pune - Pharma Production Plant
 Production of coated/ laminated
films and foils under one roof
 Dedicated facility
 106 Employees
 ISO 9001 certified
 ISO 14001 certified
 Pharmaceutical research services
- BilcareOptima™
Speed | Innovation | Happiness
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Bilcare Solutions
Singapore- Pharma Production Plant
 Production of coated/laminated
films and foils under one roof
 Dedicated facility
 90 Employees
 ISO 9001 certified
 ISO 15378 certified
 ISO 14001 certified
 Pharmaceutical research services
- BilcareOptima™
Speed | Innovation | Happiness
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Bilcare Solutions
PPI - Global Supply Position
Abbott
Merck
Actavis
Mylan
AstraZeneca
Novartis
Bayer HealthCare Pharmaceuticals
Pfizer
BMS
RB
Boehringer Ingelheim
Roche
Catalent
Sandoz
Eli Lilly
Sanofi
GSK
Stada
Johnson & Johnson
TEVA
Menarini
and many more…..
Speed | Innovation | Happiness
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Bilcare Solutions
PPI – The Bilcare Advantage
 Widest range of Pharma packaging products worldwide
 Long-term commitment and focus to Pharma industry
 Innovation and Research driven
 Technical Service
 Highest quality and GMP standards under one roof
 Complete solution provider for entire Pharma Value Chain
 Global reach, local service
Speed | Innovation | Happiness
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Bilcare Solutions
WE bilCARE
ABOUT YOU
Speed | Innovation | Happiness
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Bilcare Solutions

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