XIAOBO LI Personal Information Project Leader Department of Plant Biology Carnegie Institution for Science 260 Panama Street, Stanford, CA, 94305, USA [email protected] Tel: 517-599-6262 Education Aug. 2007-Nov. 2012: Michigan State University, East Lansing, MI, USA Ph.D., Department of Plant Biology Department of Energy-Plant Research Laboratory Sept. 2002-Jul. 2007: Xi’an Jiaotong University, Xi’an, Shaanxi, China B.E., Department of Bioengineering Research Experience Nov. 2012-present, Generation of a mutant library and characterization of lipid mutants in Chlamydomonas reinhardtii Leading a team of two technicians and one bioinformatician, guided by Martin Jonikas, Carnegie Institution for Science Aug. 2007-Nov. 2012, Ph.D. thesis project: Molecular genetics of lipid metabolism in algae and yeasts Advisors: Christoph Benning and Min-Hao Kuo, Michigan State University Jan. 2007-Jul. 2007, Bachelor thesis project: Immunogold-facilitated thermal destruction of cancer cells Advisor: Jiansheng Mei, Xi’an Jiaotong University Jun. 2006-Sept. 2006, Internship: Molecular analysis of salt-tolerant Taraxacum calli and plants Advisor: Yinxin Li, Institute of Botany, Chinese Academy of Sciences Teaching and Mentoring Experience Fall 2011, Teaching Assistant at Michigan State University. Course: Fundamental Genetics; Instructor: Dr. Barbara B. Sears. Currently leading a team of two technicians and a bioinformatician on generation of an indexed mutant library. Trained four undergraduates and one high school student on biochemistry and molecular biology. By presenting their projects, two of them won the Best Undergraduate Presentation Award on ASPB-Midwest (Fabian Brandenburg) and 1st Place on the Contra Costa County Science and Engineering Fair (Augustine Chemparathy) respectively. Publications Xiaobo Li, James G. Umen, Martin C. Jonikas. (2014) Waking sleeping algal cells. Proc Natl Acad Sci USA. doi: 10.1073/pnas.1418295111. 1 Xiaobo Li, Eric R. Moellering, Bensheng Liu, Cassandra Johnny, Marie Fedewa, Barbara B. Sears, Min-Hao Kuo, Christoph Benning. (2012) A galactoglycerolipid lipase is required for triacylglycerol accumulation and survival following nitrogen deprivation in Chlamydomonas reinhardtii. The Plant Cell. 24:4670-4686. Xiaobo Li, Christoph Benning, Min-Hao Kuo. (2012) Triacylglycerol turnover in Chlamydomonas reinhardtii requires a lipase with broad substrate specificity. Eukaryotic Cell. 11(12):1451-1462. Astrid Vieler, Guangxi Wu, Chia-Hong Tsai, Blair Bullard, Adam J. Cornish, Christopher Harvey, Ida-Barbara Reca, Chelsea Thornburg, Rujira Achawanantakun, Christopher J. Buehl, Michael S. Campbell, David Cavalier, Kevin L. Childs, Teresa J. Clark, Rahul Deshpande, Erika Erickson, Ann Armenia Ferguson, Witawas Handee, Que Kong, Xiaobo Li, Bensheng Liu, Steven Lundback, Cheng Peng, Rebecca L. Roston, Sanjaya, Jeffrey P. Simpson, Allan TerBush, Jaruswan Warakanont, Simone Zäuner, Eva M. Farre, Eric L. Hegg, Ning Jiang, Min-Hao Kuo, Yan Lu, Krishna K. Niyogi, John Ohlrogge, Katherine W. Osteryoung, Yair Shachar-Hill, Barbara B. Sears, Yanni Sun, Hideki Takahashi, Mark Yandell, Shin-Han Shiu, Christoph Benning (2012) Genome, functional gene annotation, and nuclear transformation of the heterokont oleaginous alga Nannochloropsis Oceanica CCMP1779. PLoS Genetics. 8(11): e1003064. Rachel Miller, Guangxi Wu, Rahul R. Desphande, Astrid Vieler, Katrin Gaertner, Xiaobo Li, Eric R. Moellering, Simone Zäuner, Adam Cornish, Bensheng Liu, Blair Bullard, Barbara B. Sears, Min-Hao Kuo, Eric L. Hegg, Yair Shachar-Hill, Shin-Han Shiu, Christoph Benning. (2010) Changes in transcript abundance in Chlamydomonas reinhardtii following nitrogen-deprivation predict diversion of metabolism. Plant Physiology. 154(4):1737-1752. Manuscripts in revision Fantao Kong, Tomohito Yamasaki, Sari Dewi Kurniasih, Xiaobo Li, Nina Ivanova, Shigeru Okada, Takeshi Ohama. (2014) Robust expression of heterologous genes by selection marker fusion system in improved Chlamydomonas strains. Journal of Bioscience and Bioengineering. In revision. Manuscripts in preparation Xiaobo Li*, Ru Zhang*, Weronika Patena*, Spencer S. Gang, Sean R. Blum, Nina Ivanova, Rebecca Yue, Arthur R. Grossman, Martin C. Jonikas. Construction of an indexed mutant library to enable reverse genetics studies of biological processes in Chlamydomonas reinhardtii. In preparation for eLife. (*, equal contribution) Xiaobo Li, Martin Jonikas. (2014) High-Throughput Genetics strategies for identifying new components of lipid metabolism in the alga Chlamydomonas reinhardtii. Lipids in plant and algae development. (Edited by Yonghua Li-Beisson and Yuki Nakamura). Invited; in preparation. Wenqiang Yang*, Tyler Wittkopp*, Xiaobo Li, Jaruswan Warakanont, Rick Kim, Claudia Catalanotti, Eva MC Mowack, Munevver Aksoy, Sarah D’Adamo, Luke 2 Mackinder, Dudley Page, Mark Heinnickel, Xenie Johnson, Alexandra Dubini, Jean Alric, Martin Jonikas, Christoph Benning, Sabeeha Merchant, Matthew C. Posewitz, Arthur R. Grossman. Finding the Way in the Dark: the Impact of a Mutant in FDX5 on Growth and Membrane Structure in Chlamydomonas reinhardtii. In preparation. (*, equal contribution) Wenqiang Yang, Tyler Wittkopp, Claudia Catalanotti, Xiaobo Li, Matthew C Posewitz, Arthur R Grossman. Acetate Kinase 1 is the Main Enzyme for the Acetate Assimilation in the Dark in Chlamydomonas reinhardtii. In preparation. Witawas Handee, Xiaobo Li, Min-Hao Kuo. Intracellular triacylglycerol accumulation is required for long-term survival of Saccharomyces cerevisiae quiescent cells. In preparation for Proc Natl Acad Sci USA. Patents Christoph Benning, Xiaobo Li, Bensheng Liu, Min-Hao Kuo, Barbara B. Sears. Method to Increase Algal Biomass and Enhance its Quality for the Production of Fuel. US20140134685 A1. Presentations Oral Presentations Invited by Institutions or International Conferences 2014 The 16th International Conference on the Cell and Molecular Biology of Chlamydomonas, Pacific Grove, CA, USA: “An indexed mutant library to transform Chlamydomonas research” 2013 College of Life Science and Technology Seminar, Jinan University, Guangzhou, China: “Triacylglycerol biosynthesis in microalgae” 2013 Hans Kende Memorial Lecture, MSU-DOE Plant Research Lab, East Lansing, MI, USA: “Fatty acid export from the plastid: biochemistry, genetics and genomics” 2011 Plant Biology-American Society of Plant Biologists, Minneapolis, MN, USA: “Characterization of Chlamydomonas lipase candidates involved in triacylglycerol metabolism” 2011 The First International Conference on Algal Biomass, Biofuels and Bioproducts, St. Louis, MO, USA: “Characterization of Chlamydomonas lipase candidates involved in triacylglycerol metabolism” 2009 Gordon Research Conference-Plant lipids, Galveston, TX, USA: “Regulation of triacylglycerol biosynthesis and degradation in Chlamydomonas reinhardtii” Poster Presentations on International Conferences 2013 Plant Biology-American Society of Plant Biologists, Providence, RI, USA: “Use of a green algal mutant library to understand plant lipid metabolism” 2011 Symposium on Transcriptional Dynamics, Evolution, and Systems Biology, East Lansing, MI, USA: “Characterization of Chlamydomonas lipase candidates involved in triacylglycerol metabolism” 2010 The 14th International Conference on Chlamydomonas, Norton, MA, USA: 3 “Characterization of Chlamydomonas triacylglycerol lipase candidates” Awards and Fellowships 2013 “Hans Kende Award”, for “best dissertation” selected from all plant science dissertations at MSU, Department of Energy Plant Research Lab 2013 “Bessey Award” for Ph.D. dissertation, MSU Department of Plant Biology 2013 Travel Grant, American Society of Plant Biologists 2011 Second Prize for oral presentation, The 9th Plant Science Graduate Student Research Forum-basic science group, MSU 2011 “Paul Taylor Award”, MSU Department of Plant Biology 2009-2010 GEDD Fellowship, Gene Expression in Development and Disease Focus Group, MSU 2009 Travel Fund, Gordon Research Conference-Plant lipids 2007 CNPC Scholarship, China National Petroleum Corporation 2005 “Student Leadership Prize”, Xi’an Jiaotong University 2005 Chinese Academy of Sciences Scholarship 2004-2005 National Scholarship, The Ministry of Finance and the Ministry of Education, People’s Republic of China 2004 First Prize in Contest of Advanced Mathematics of Shaanxi Province, Mathematic Association of Shaanxi Province Academic Service and Memberships 2013-present Editorial Board, Plant Signaling & Behavior 2011-present Member, American Society of Plant Biologists Independently reviewed articles for: The Plant Cell; Plant Physiology; New Phytologist; Plant Molecular Biology; BMC Systems Biology; Journal of Integrative Plant Biology; Molecular Biology Reports; American Journal of Molecular Biology; Journal of Applied Phycology; Biofuel Research Journal; BMC Research Notes; International Conference on Systems Biology 2012 and 2013; Bio-protocol 4
© Copyright 2024 ExpyDoc
