Program

UC Davis Cardiovascular Symposium 2014
Systems Approach to Understanding Cardiac Excitation-Contraction Coupling and Arrhythmias
— Na+ channel and Na+ transport
Organizing Committee
Advisory Board
Donald M Bers, Ph.D. (Chair)
Ye Chen-Izu, Ph.D. (Organizer)
Colleen Clancy, Ph.D.
Sanda Despa, Ph.D.
Frederick Meyers, M.D.
Kyriacos Athanasiou, Ph.D.
Reginald Low, M.D.
Lars Maier, M.D. Ph.D.
Nipavan Chiamvimonvat, M.D.
Saul Schaefer, M.D.
Wine Tour and Dinner Reception for Invitees
Transportation: Symposium invitees (speakers, discussion leaders and panelists) will meet at 1:30 PM in the
Biophysical Society Meeting registration area in the San Francisco Moscone Center, and then walk together to
the UC Davis bus. The bus for the wine tour and dinner will depart at 2:00 PM, go to Tamber Bey Vineyards
at 3pm, and to the Culinary Institute of America at 5:30pm.
Name Card: Please use your Biophysics Badge as your name card for the UC Davis symposium.
Feb. 19 (Wed.)
Symposium Program
Feb.20 (Thurs.)
8:00 AM - 5:00 PM
7:30 AM
Coffee and light pastry
8:00 – 10:00 AM
8:00 – 8:40
8:40 – 9:20
9:20 – 10:00
Session-I: Na+-induced arrhythmias: from cellular level to the whole heart
Experimental studies – Penny Boyden
Modeling studies – James Weiss
Panel discussion: Critical issues & Controversies – Ole Sejersted (lead)
Jonathan Lederer, Leighton Izu, Zhilin Qu, Livia Hool
10:00 – 12:00 PM
10:00 – 10:40
10:40 – 11:20
11:20 – 12:00
Session-II: Disruption of Na+ homeostasis
Na balance in the normal heart - Sanda Despa
Altered Na homeostasis in heart disease - Brian O’Rourke
Panel discussion: Critical issues & Controversies - Don Bers (lead)
Alicia Mattiazzi, William Louch, Christoph Maack, Sridharan Rajamani
12:00 -1:00 PM
Lunch on site for all attendees /Trainees Career Luncheon in Founders Board Room
1:00 – 3:00 PM
1:00 – 1:40
1:40 – 2:20
2:20 – 3:00
Session-III: Na+ channel structure and function
Structural studies – William Catterall
Modeling studies – Vladimir Yarov-Yarovoy
Panel discussion: Critical issues & Controversies – Richard Aldrich (lead)
Mark Cannell, Walter Chazin, Eric Sobie, Jon Sack
3:00 – 5:00 PM
3:00 – 3:20
3:20 – 3:40
3:40 – 4:00
4:00 – 4:20
4:20 – 5:00
Session-IV: Na+ channel regulation
Experimental studies – Hugues Abriel
Experimental studies – Ye Chen-Izu
Modeling studies – Victor Maltsev
Modeling studies – Thomas Hund
Panel discussion: Critical issues & Controversies - Geoffrey Pitt (lead)
Eleonora Grandi, Randall Rasmussen, Lars Maier, Al George, Céline Marionneau
5:15 – 6:45 PM
7:00 – 9:30 PM
Tour of Mondavi Food and Wine Institute (invitees only)
Dinner & social mixing for registered attendees (Buehler Alumni Center)
Feb.21 (Friday)
7:00 AM - 4:00 PM
6:40 AM
Coffee and light pastry
7:00 – 9:00 AM
7:00 – 7:40
7:40 – 8:20
8:20 – 9:00
Session-V: Trafficking, sequestration and complexing
Sequestration – Peter Mohler
Trafficking – Isabelle Deschênes
Panel discussion: Critical issues & Controversies – Robin Shaw (lead)
Nip Chiamvimonvat, Robert Harvey
9:00 – 11:00 AM
9:00 – 9:40
9:40 – 10:20
10:20 – 11:00
Session-VI : Na/Ca exchanger – structure, function and regulation
Structure studies - Michela Ottolia
Function studies – Karin Sipido
Panel discussion: Critical issues & Controversies – John Bridge (lead)
Joshua Goldhaber, Kenneth Philipson, Andy Edwards
11:00 AM -12:00 PM Lunch on site for all attendees
12:00 – 2:00 PM
12:00 – 12:40
12:40 – 1:00
1:00 – 1:20
1:20 – 2:00
Session-VII: Na/K pump – structure, function and regulation
Structure and function – Julie Bossuyt
Na/K-ATPase in disease - Jerry Lingrel
Na/K-ATPase in disease - Mike Shattock
Panel discussion: Critical issues & Controversies – Mordecai Blaustein (lead)
Jack Kaplan, Zi-Jian Xie
2:00 – 4:00 PM
2:00 – 2:40
2:40 – 3:20
3:20 – 4:00
Session-VIII: Therapeutics
Experimental studies – Robert Kass
Modeling studies – Colleen Clancy
Panel discussion: Critical issues & Controversies – Luiz Belardinelli (lead)
Andras Varro, Laszlo Csernoch, Antonio Zaza, Bernard Fermini, Crystal Ripplinger
4:00 PM
Bus departure to San Francisco Airport and Moscone Center
Logistics
Trainee and Guest Registrations are due Feb. 1st, 2014.
Please register with Ms. Maria Horan ([email protected]) and send her a check for the
registration fee payable to UC Regents (Fed Tax ID: 94-6036494).
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
US$50 for trainee (student, post-doc)
US$200 for non-trainee
The registration fee will also cover light pastry, coffee, lunches, and the dinner/social mixing for all
registered attendees on Feb.20 (Thur.) at the conference site.
Transportation from San Francisco to Davis on Feb.19 (wed.)
Symposium invitees (speakers, discussion leaders and panelists) will meet at 1:30 PM in
the Biophysical Society Meeting registration area in the San Francisco Moscone Center,
and then walk together to the UC Davis bus.
The bus will depart at 2pm for the wine tour and dinner (see below) and then to Davis.
Tamber Bey Vineyards (~ 3-5PM)
1251 Tubbs Lane,
Calistoga, CA 94515
phone 707-942-2104
Culinary Institute of America (CIA at Greystone, ~5:30-8:30PM)
2555 Main Street,
St. Helena, CA 94574
Phone: 707-967-1100
Transportation from Davis to San Francisco at 4pm on Feb.21 (Fri.)
The bus will depart at 4pm from the conference site, drive to the San Francisco Airport,
and then to the Moscone Center at downtown San Francisco. If you need a ride, please
reserve your seat by emailing to Maria Horan ([email protected]) before Jan.25.
Other local transportation:
Amtrak (between San Francisco and Davis)
Taxi (~$55 to SAC, ~$170 to SF; the cost can be reduced by sharing a ride.)
Airport shuttle (530-756-6715, 800-565-5153, ~25 minute to Sacramento, ~1.5 hour
to SFO airport)

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