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PSORIASIS
Psoriasis is an immune-mediated, non-contagious chronic inflammatory skin disorder of unknown cause
AN ESTIMATED
WORLDWIDE
HAVE PSORIASIS 1
Health Economics
Psoriasis can have a significant impact on the healthcare system and work productivity
TOTAL ESTIMATED U.S. COST
BILLION
Due to
medical expenses
and lost wages2
MALES
OCCURS NEARLY EQUALLY IN
Symptoms
Diagnosis
UP
TO
FEMALES
3.6
80%
MILLION
live with undiagnosed
psoriasis in the U.S.8
DELAY
}
Increased risk for
other health conditions
CROHN’S
DISEASE
STOPPED
WORK5
39%
REPORT
WORK-RELATED
DISABILITY6
42%
EXPERIENCED
LIMITATIONS
IN JOB
PROSPECTS7
MORE
THAN
people with moderate
to severe psoriasis
AVERAGE
26
vs.
DAYS
4
ABOUT
3
average healthy adults
Unmet Medical Need
89% self-conscious
89% angry
HEART
DISEASE
12%
87% helpless
52%
87% embarrassed
81% disfigured5
TWO
YEARS9
OFTEN APPEARS BETWEEN
MISSED
Effect on Emotional Well-being
DIABETES
OBESITY
HEART
ATTACK
HIGH BLOOD
PRESSURE
PSORIATIC
ARTHRITIS
DEPRESSION 2
elbows knees lower back scalp2
AVERAGE
ON TOTAL HEALTHCARE
TO THEIR ILLNESS
Comorbidities
WHO DEVELOP PSORIASIS
HAVE PLAQUE PSORIASIS
patches of raised, reddish skin
covered by silvery-white scales
that appear on these locations
~60%
OF WORK DUE
2
ANNUAL SPENDING
ANNUALLY
AGES 15-30
2
SEVERITY VARIES
63.8% 59.7%
10
46.1%
Symptoms on a regular basis
Itching
Irritation
Burning
or stinging
88%
Impact on Social Perceptions
94% problem in daily life
88% affects overall emotional well-being
82% interferes with enjoyment of life5
of psoriasis
patients were
dissatisfied with
their treatment11
of psoriasis
patients with a
body surface
area of ≥ 4
palm lesions
were receiving
no treatment or
topical therapy
alone9
World Psoriasis Day Consortium. "Key Communication Messages." Key Communication Messages. Accessed 23 Dec. 2013. http://www.worldpsoriasisday.com/web/page.aspx?refid=110.
National Psoriasis Foundation. (2013). Media kit. Retrieved from http://www.psoriasis.org/file/communications---all-documents/MediaKit.pdf.
Horn, E., et al. Association of patient reported psoriasis severity with income and employment. J Am Acad Dermatol. 2007 Aug; 57(6):963-71.
4
Yu, A.P., et al. Economic burden of psoriasis compared to the general population and stratified by disease severity. Current Medical Research Opinion. 10: 2429-438.
5
Armstrong, A.W., et al. Quality of life and work productivity impairment among psoriasis patients: findings from the National Psoriasis Foundation survey data 2003-2011. PLoS One. 7.12 (2012): e52935. doi: 10.1371/journal.pone.0052935.
6
Verstappen, SM., et al. Working status in patients with rheumatoid arthritis ankylosing spondylitis and psoriatic arthritis: results from the British Society for Rheumatology Biologics Register. Rheumatology. 49.8 (2010): 1570-7. doi: 10.1093/rheumatology/keq131.
7
Ayala, F. The impact of psoriasis on work-related problems: a multicenter cross-sectional survey. J Eur Acad Dermatology. (2013): doi:10.1111/jdv.12233.
8
Kurd, S.K., Gelfand, JM. The prevalence of previously diagnosed and undiagnosed psoriasis in US adults: results from NHANES 2003-2004. .J Am Acad Dermatol. 60.2(2009): 218-24. doi: 10.1016/j.jaad.2008.09.022.
9
Lebwohl M, Bachelez H, Barker J, et al. Patient perspectives in the management of psoriasis: Results from the population-based Multinational Assessment of Psoriasis and Psoriatic Arthritis Survey. Journal of the American Academy of Dermatology. 2014,
http://www.jaad.org/article/S0190-9622(14)00977-3/abstract.
10
Sampogna, F., et. al. Prevalence of symptoms experienced by patients with different clinical types of psoriasis. British Journal of Dermatology. 151.3 (2004): 549-599. doi:10.1111/j.1365-2133.2004.06093.x
11
Armstrong, A.W., et al. Undertreatment, Treatment Trends, and Treatment Dissatisfaction Among Patients With Psoriasis and Psoriatic Arthritis in the United States. Findings From the National Psoriasis Foundation Surveys, 2003-2011. JAMA Dermatology. 2013.
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