Performing Optimal CPR 1. Begin using the ResQPOD and performing chest compressions as soon as cardiac arrest is confirmed. Do not delay chest compressions! 2. Remove the ResQPOD if a pulse returns. 3. Ventilate over 1 second (until chest rises) with both secured and unsecured airways; do not hyperventilate! 4. Assure that the chest wall recoils completely after each compression. 5. Provide chest compressions at a depth of 1.5 - 2” and a rate of 100/ min. Timing assist lights can be used to guide the chest compression/ release rate: 100/min = 10 compressions/light flash. 6. Avoid unnecessary delays or interruptions in chest compressions. 7. Remove secretions from ResQPOD by shaking or blowing out with the ventilation source. Clinical Data The ResQPOD, or an earlier version of the ITD, has been evaluated in over 10 animal and 7 clinical studies (www.advancedcirculatory.com). These studies have shown that the ResQPOD doubles blood flow to the heart and brain, and significantly increases circulation and survival in out-of-hospital cardiac arrest. In a Milwaukee (WI) study of cardiac arrest patients undergoing conventional CPR, systolic blood pressure and 24-hour survival rates in patients presenting in a rhythm other than asystole almost doubled when an active (functional) ITD was used compared to a sham (placebo) ITD (p<0.05 for both). 90 35 80 30 mmHg 70 60 50 40 25 20 % 15 S ha m Strengthening the Chain of Survival An impedance threshold device is recommended in the 2005 AHA guidelines as the only Class IIa CPR device to improve hemodynamics and increase the return of spontaneous circulation during cardiac arrest Act ive 30 10 20 10 5 0 0 Systolic BP after 14 minutes of ITD use1 Survival to 24 Hours2 1Pirrallo et al. Effect of an inspiratory ITD on hemodynamics during conventional manual CPR. Resuscitation 2005;66:13-20. 2Aufderheide et al. Clinical evaluation of an inspiratory ITD during standard CPR in patients with out-of-hospital cardiac arrest. Crit Care Med 2005;33(4):734-40. The generally cleared indication for the ResQPOD is for a temporary increase in blood circulation during emergency care, hospital, clinic and home use. Studies are ongoing in the United States to evaluate the long-term benefit of the ResQPOD for indications related to patients suffering from cardiac arrest, hypotension during dialysis and severe blood loss. This communication is not intended to imply specific outcome-based claims not yet cleared by the US FDA. 49-0336-000, 02 7615 Golden Triangle Drive, Suite A Eden Prairie, MN 55344 USA Phone: 866-314-1596 www.advancedcirculatory.com ResQPOD® Circulatory Enhancer The ResQPOD is an impedance threshold device that provides Perfusion on Demand by regulating pressures in the thorax during states of hypotension. Animal and clinical studies have shown that during CPR, the ResQPOD: • Doubles blood flow to the heart • Increases blood flow to the brain by 50% • Doubles systolic blood pressure • Increases survival rates • Increases the likelihood of successful defibrillation • Provides benefit in all arrest rhythms • Circulates drugs more effectively The American Heart Association, in their 2005 Guidelines, gave an impedance threshold device (e.g. ResQPOD) a Class IIa recommendation to increase blood flow and immediate survival rates in patients in cardiac arrest. It is the most highly recommended CPR adjunct in the new Guidelines and carries a higher recommendation than any medication used to increase circulation in adults in cardiac arrest. The ResQPOD is the only impedance threshold device on the market. The ResQPOD is easy to use. It provides a unique way to increase circulation during CPR by refilling the heart after each chest compression. In addition, timing assist lights on the ResQPOD help provide guidance on the proper compression and ventilation rates. How it Works The ResQPOD prevents unnecessary air from entering the chest during CPR. When air is prevented from rushing into the lungs as the chest wall recoils, the vacuum (negative pressure) in the thorax is greater. This enhanced vacuum pulls more blood back to the heart, doubling blood flow during CPR. Studies have shown that this mechanism increases cardiac output, blood pressure and survival rates. Patient ventilation and exhalation are not restricted in any way. Using the ResQPOD on a Facemask 1. Connect ResQPOD to facemask. 2. Open airway. Establish and maintain tight face seal with mask throughout chest compressions; a head strap or 2-handed technique is recommended. 3. Connect ventilation source to ResQPOD, or mouthpiece if performing mouth to mask ventilation. 4. Perform CPR @ recommended compression to ventilation ratio. Mouth to Mask Using the ResQPOD on an ET Tube 1. Confirm ET tube placement and secure with commercial tube restraint. 2. Connect ResQPOD to ET tube. 3. Connect ventilation source to ResQPOD. 4. Perform continuous chest compressions. 5. Remove clear tab and turn on timing assist lights. Ventilate asynchronously @ timing light flash rate of 10/min. 6. Administer ET meds directly into ET tube. 7. Place ETCO2 detector between ResQPOD and ventilation source.