CURRICULUM VITAE NAME: Gulshan Sharma, M.D., M.P.H., F.C.C.P DATE: September 19, 2014 PRESENT POSITION AND ADDRESS/BIOGRAPHICAL: 06/2011 to Present Director, Division of Pulmonary Critical Care and Sleep Medicine The University of Texas Medical Branch 301 University Blvd. Galveston, Texas 77555-0561 TEL: 409-772-2436 FAX: 409-772-9532 Email: [email protected] EDUCATION: 06/1988 to 03/1990 Premedical DAV College Chandigarh, India 07/1990 to 05/1995 M.B.B.S. Dayanand Medical College Ludhiana, India 08/1995 to 03/1996 Externship Internal Medicine, Dermatology, Psychiatry, Surgery The University of Texas Medical Branch Galveston, Texas 07/1997 to 06/2000 Residency Internal Medicine Henry Ford Hospital Detroit, Michigan 07/2000 to 06/2001 Chief Resident Internal Medicine Henry Ford Hospital Detroit, Michigan 07/2001 to 06/2004 Fellow Pulmonary & Critical Care Department of Internal Medicine Yale University School of Medicine New Haven, Connecticut Gulshan Sharma, M.D. Page 2 EDUCATION (continued) 09/2002 to 12/2003 MPH Degree Yale University School of Epidemiology Public Health New Haven, Connecticut NON DEGREE EDUCATION 08/2007 Clinical Safety and Effectiveness Course The University of Texas M.D. Anderson Cancer Center Houston, TX 10/2012 Annual Research Intensive Institute for Patient-Centered Comparative Effectiveness Oregon Health & Science University 2013 Patient Safety System Lifewings® UTMB, Galveston 11/2013 Leadership Development for Physicians in Academic Health Centers Harvard School of Public Health, Boston 2/2014 The Leadership Challenge® Workshop UTMB, Galveston 4/2014 Strategy for Healthcare Delivery Value Based Healthcare Delivery Leadership Workshop Texas Medical Center, Houston, TX BOARD CERTIFICATION: American Board of Internal Medicine Certified: August 6, 2000 (expired 2010) American Board of Internal Medicine Pulmonary Diseases Certified: November 5, 2003 Recertified: 2013 American Board of Internal Medicine Critical Care Medicine Certified: November, 2004 Recertified: 2013 LICENSURE INFORMATION: Gulshan Sharma, M.D. Texas Medical License Page 3 Expiration 11-20-2014 PROFESSIONAL AND TEACHING EXPERIENCE: 09/2014 – Present Professor Department of Internal Medicine University of Texas Medical Branch Galveston, Texas 04/2014-Present Associate Chief Medical Officer 05/2013-3/2013 Interim Associate Chief Medical Officer Quality and Patient Safety UTMB Health System 06/2011- Present Training Program Director, P&CCM Fellowship Program, Department of Internal Medicine University of Texas Medical Branch Galveston, Texas 06/2011 - Present Director, Medical Intensive Care Unit John Sealy Hospital and TDCJ-ICU University of Texas Medical Branch Galveston, Texas 09/2009 - Present Member, Institute for Translational Sciences Scientific Review Committee (ITS-SRC) – UTMB 09/2009 - Present Associate Professor Division of Pulmonary and Critical Care Medicine Department of Internal Medicine University of Texas Medical Branch Galveston, Texas 04/2005 – 5/2011 Associate Program Director P&CCM Fellowship Program Department of Internal Medicine University of Texas Medical Branch Galveston, Texas 07/2004 to 08/2009 Assistant Professor Gulshan Sharma, M.D. Page 4 Division of Allergy, Pulmonary, Immunology, Critical Care, and Sleep Department of Internal Medicine University of Texas Medical Branch Galveston, Texas RESEARCH ACTIVITIES: Current: Grants U01AG048270 Volpi, E (PI) 7/1/2014 – 6/30/2019 NIA/PCORI The STRIDE Study STRIDE is a large pragmatic trial of a care management strategy to reduce fall-related injuries among patients 75 years of age or older. STRIDE research activities are coordinated by investigators at Harvard, UCLA and Yale. Co-Investigator: Gulshan Sharma, MD (5% effort) 2R01 AG033134 Goodwin, J (PI) 9/1/2011 - 08/31/2014 NIH/NIA $298,436 Care of the Elder Hospitalized Patient: The Role of Hospitalists Goal: This project studies the impact of hospitalists on the care of older hospitalized patients using a 5% national sample of Medicare charge data from 1995 through 2010, and 100% Medicare data from Texas for 2000-2010. Co-Investigator: Gulshan Sharma, MD (10% effort) P30 AG017231 – NIH National Institute on Aging 5/1/2010-4/30/2015 NIH/NIA $780,593/year The major goals of this center grant is to conduct basic and clinical research on ways for elderly Americans to lead a more independent life for as long as possible. The center is focused on the effect of aging on skeletal muscle and protein metabolism. The ability of androgens and nutritional supplements to reduce the loss of muscle in the elderly is tested. PI: Elena Volpi MD RCDC Career Development Scholar: Gulshan Sharma, MD (50% effort) UTMB Claude Pepper Older Americans Independence Center (OAIC) The University of Texas System Chancellor’s Health Fellow for Health Information Technology Grant Integrated Computer Based Clinical Decision Support System to improve care transition of patients hospitalized for Congestive Heart Failure (CHF) and Chronic Obstructive Pulmonary Disease (COPD) (No cost extension) PI: Gulshan Sharma, MD 9/1/2010 – 8/31/2015 UT Health System Health IT $500,000 The University of Texas System Chancellor’s Health Fellow for Systems Engineering Grant Gulshan Sharma, M.D. Page 5 Systems engineering to provide Integrated care for patients with Chronic Obstructive Pulmonary Disease (COPD) PI: Gulshan Sharma, MD 6/1/2012 – 5/31/2015 UT Health System Health IT $300,000 1R24HS022134-01 Goodwin (PI) 05/01/13-04/30/18 AHRQ Patient Centered Outcomes Research in the Elderly The goal of Patient Centered Outcomes Research in the Elderly is to transform UTMB into a center of rigorous high quality comparative effectiveness research (CER) and patient-centered outcomes research (PCOR), focused on healthcare decision-making facing older individuals, their providers, and the health systems providing their care. Co-investigator: Gulshan Sharma (5% effort) Past NIH: K08 AG31583-01- National Institute on Aging Continuity of care and end of life ICU use – Mentored Oriented Career Development Award - K08 PI: Gulshan Sharma, MD (75% effort) 9/1/2008 – 8/30/2013 NIH/NIA $593,000 R01 AG 033134-01 – National Institute on Aging Care of the elder hospitalized patients: the role of hospitalists PI: James S Goodwin MD Co-Investigator: Gulshan Sharma, MD (10% effort) 9/15/2009 – 9/31/2011 NIH/NIA $656,488 Other: Protocol#04-039: A Randomized, Double-blind, Placebo-Controlled, Phase II Study to Assess the Safety and Efficacy of Cytomegalovirus gB/MF59 Vaccine in Preventing Systemic Cytomegalovirus Infection in Health Adolescent Females. 7/2008-Present PI: Larry Stanberry, MD Member Data Safety Monitoring Board (DSMB): Gulshan Sharma, MD WELPICUS STUDY "Consensus Guidelines for Worldwide End of Life Practice for Patients in Intensive Care Units. PI: Charlie Sprung MD. 2009 - Present The project consists of 3 dependent clusters of work packages: 1. Develop consensus definitions for EOL decisions (WP 1). 2. Develop Worldwide Consensus Guidelines for best EOL practices (WP 2). 3. Valorisation of the results (WP 3). The work will be carried out by an international network in the fields of ethics and science of a) ICUs whose researchers have a proven interest in intensive care, education, and ethics, b) A consortium of intensive care society representatives from countries worldwide including Europe, North and South America, South Africa, Japan, PR China, Korea, India, Hong Kong, Australia/New Zealand and the World Federation of Societies of Intensive and Critical Care Medicine and c) experts in medical specialties, nursing, ethics, theology, sociology, gerontology, law, education, media and public policy. Gulshan Sharma, M.D. Page 6 Past Other: The University of Texas System Chancellor’s Health Fellow for Health Information Technology Grant Enabling Peer Researchers Access to i2B2 PI: Ralph Farr Co-investigator: Gulshan Sharma, MD 9/1/2010 – 8/31/2012 UT Health System Health IT $500,000 A Phase 4, Randomized, Double-Blind, Multi-Center, Comparator Study Evaluating the Safety and Efficacy of Dexmedetomidine Compared to IV Midazolam in ICU Subjects Requiring Greater than Twenty-Four Hours of Continuous Sedation. 7/2006-6/2009 Co-Investigator; Gulshan Sharma, MD PI: Victor J Cardenas, MD Site: UTMB, Galveston, TX. A Two-Week, Randomized, Modified-Blind, Double-Dummy, Parallel Group Efficacy and Safety Study of Arformoterol Tartrate Inhalation Solution Twice-Daily, Tiotropium Once-Daily,, and Arformeterol Tartrate Inhalation Solution Twice-Daily and Tiotropium Once-Daily (Dosed Sequentially) in Subjects with Chronic Obstructive Pulmonary Disease. 6/2006-7/2007 PI: William C. Calhoun, MD Co-Investigator; Gulshan Sharma, MD Site: UTMB, Galveston, TX. A Phase 2 Study to determine the efficacy and safety of Sivelestat in Subjects with Acute Lung Injury. 7/2002- 6/2004 Co-Investigator; Gulshan Sharma, MD PI: Mark Siegal, MD Site: Yale New Haven Hospital, New Haven, CT. A Double-Blind, Placebo-Controlled, Parallel, Multicenter Study on extended VTE Prophylaxis in Acutely Ill Medical Patients with Prolonged Immobilization. 7/2002- 6/2004 Co-Investigator; Gulshan Sharma, MD PI: Mark Siegal, MD Site: Yale New Haven Hospital, New Haven, CT. A randomized, multicenter, open label trial comparing intravenous zithromax (azithromycin) plus intravenous rocephin (ceftrioxone) followed by oral zithromax with intravenous levaquin (levofloxacin) followed by oral levaquin for the treatment of moderate to severely ill hospitalized subjects with community-acquired pneumonia. 7/1999-6/2001 Co-Investigator; Gulshan Sharma, MD PI: Bruno DiGiovine, MD Site: Henry Ford Health System Detroit, MIZ A randomized, double-blind, phase III, comparative study of Cidecin (Daptomycin) to rocephin Gulshan Sharma, M.D. Page 7 (ceftrioxone) in the treatment of moderate to severe community-acquired acute bacterial pneumonia due to S. pneumoniae. 6/1998-5/2000 Co-Investigator; Gulshan Sharma, MD PI: Bruno DiGiovine Site: Henry Ford Health System Detroit, MI COMMITTEE RESPONSIBILITIES: UTMB 2014 2013 - Present 2013 - Present 2013 - Present 2013 - Present 2012 - Present 2012 - Present 2012 - Present 2011 - Present 2011 - Present 2009 - Present 2008 - 2013 2007 - 2012 2006 - 2013 2006 - 2013 2013 2011 2011 2010 - 2011 2009 2007 - 2012 2007 - 2011 2007 2006 - 2011 2006 - 2008 2006 2006 Chair, Self-study Committee, Department of Internal Medicine 6 year review R-24 Operations Committee Health System Clinical Strategy and Operations Committee IT Planning Task Force Operations Council Chair, Core Measures Task Force Committee Member-at-Large on the Medical Staff Executive Committee Member, Sealy Center on Aging Leadership Committee Bundled Payment Committee Member, Steering committee for CSE course at UTMB Internal Medicine Leadership Committee Member, Institutional Translational Science-Scientific Review Committee (ITS-SRC) Member, Department of Internal Medicine, Quality Improvement Steering Committee Division Lead for EPIC implementation Resident Advisory Committee, Department of Internal Medicine Member, Rapid Response Team Committee Member, Search Committee Vice President of Ambulatory Operations Member Search Committee, Sleep Medicine Director Member Search Committee, Director, Heart Failure Program Chair, Search Committee - Director, Division of General Medicine Chair, Search Committee - Health Economist, Division of Geriatrics, Sealy Center on Aging. Member, Allergy and Immunology Fellows Research Advisory Committee Chair, Anticoagulation Committee Physician Liaison at UTMB: University Health System Consortium. Deep Vein Thrombosis/Pulmonary Embolism Benchmarking Project. Member, Quality Improvement Committee, Department of Internal Medicine Member, Physician Advisory Group, Department Internal Medicine Member, External Ventilatory Support, University Hospitals Member, Development and Implementation of Induced Hypothermia Gulshan Sharma, M.D. 2006 Non UTMB Page 8 Protocol Member, ICU Sedation Protocol Committee Co-Chair, 67th Koppa Conference, Mo Ranch, Tx – Aug 2014 Regional meeting of pulmonary, critical care, and sleep specialist across state of TX. TEACHING RESPONSIBILITIES: EDUCATION Medical Students 7/2005 – 6/2011 Cardiovascular Pulmonary (CVP) Core Lecture for Second Year Medical Students Ventilation-Perfusion Relationships Hypoxia Respiratory Failure Facilitator for CVP problem based learning (PBL) for Second Year Medical Students - (6hrs. per week for 6 weeks / yr.) May 2008 - 2011 Lecture on Great Syndromes – ARDS 2004 2006 Examiner, Medical Student OSCE Judge, Medical Student Research Forum Internal Medicine Housestaff 7/2004 –6/2008 Facilitate daily morning reports (1hr 2-3 times per months) 7/2005 – 2012 Core Pulmonary & Critical Care Medicine Lectures to Internal Medicine House Staff: Yearly Acute Respiratory Distress Syndrome COPD Hemodynamic Monitoring Pleural Diseases Sepsis Shock-Pathophysiology and Management - Referee, Internal Medicine Quarterly Morbidity & Mortality Conference – 2005 - Weekly Morbidity & Mortality Conference in MICU during service months (3months/year) Pulmonary Critical Care Medicine Fellows Gulshan Sharma, M.D. Page 9 2005 to present Core Pulmonary & Critical Care Medicine Lectures: Yearly Sepsis Acute Respiratory Distress Syndrome Pleural Diseases Hemodynamic Monitoring Role of hypothermia in ICU Health Care Associated Pneumonia Ageing Lung Ageing and COPD EOL ICU use Smoking Cessation Sedation & Analgesia Clinical Study Design & Statistics 2005 – Present Moderator, Monthly Journal Club 2005 – 2009 Moderator, Pulmonary Board Review Series Rheumatology Fellows 2009 – Present Connective tissue disorder associated pleura-pulmonary Disease Geriatrics 2011 – Present COPD in Older adults Mentoring: Name Sattar, F Title Pulmonary & Critical Care Medicine Fellow Terminella, L Pulmonary & Critical Care Medicine Fellow Pulmonary & Critical Care Medicine Fellow Pulmonary & Critical Care Medicine Fellow Jain, A Imad, M Babu, R Pulmonary & Critical Care Medicine Fellow Project Obesity hypoventilation syndrome. An under recognized entity. Selected as Top 20 posters (out of 3000)at ACCP 2005 mtg. Diagnostic studies in patients with acute respiratory distress syndrome (ARDS). Is etomidate really a culprit in relative adrenal insufficiency in patients with septic shock? A case in point: What caused this patient’s cough and hemoptysis? Ventilator associated pneumonia and mortality in mechanically ventilated obese patients A 57-Year-Old Man with Abdominal Pain, Jaundice, and History of a Blood Transfusion." (First prize in infectious disease category at ACCP 2006) Babu R, Gulshan Sharma, M.D. Espino, D Post-doc Pharm D Rastogi, S House-staff Internal Medicine Post-doc Pulmonary & Critical Care Medicine Fellow Pulmonary & Critical Care Medicine Fellow House-staff Internal Medicine Lemus, Frank C Murugan, Anandhi Naik, Shantanu Goyal, Geetinder Garza, Gutirrez Pulmonary & Critical Care Medicine Fellow Tran, Tru Post-doc Pharm D Shah, S House-staff Internal Medicine Pulmonary & Critical Care Medicine Fellow House-staff Internal Medicine House-staff Internal Medicine Prys-Picard, Curig Jatwani, S Ubhayker, K Page 10 Cardenas Jr. V, Sharma G Acute Respiratory Distress Syndrome from Chlorine Inhalation during a Swimming Pool Accident: A Case Report and Review of the Literature. Babu R, Sharma G. A 39-Year-Old Man with Epigastric Pain, Intermittent Chest Pain, and Progressive Dyspnea. Incidence of Severe Hypokalemia in Septic Shock Patients with Relative Adrenal Insufficiency Receiving Hydrocortisone. Pattern of cardiac troponin release in patients without acute coronary syndrome. Kempner Postdoctoral Scholar Award Obesity and Lung Diseases. Review article. Chr. Resp. Diseases. Quality Improvement Project: UTMB compliance with Sepsis bundle (QI project) Implementation and outcomes of Hypothermia Protocol in post arrest patients. (QI project) End of life ICU use in state Prisoners Retrospective review of risk factor in hospitalized patients with community MRSA Identifying harm in patients on oral anticoagulation therapy using electronic health record (QI Project) Role of RRT’s in academic center. Does it work? Multiple use of Vasopressors and outcomes (MUPPET) A retrospective review of PCR positive H1N1 cases Focused educational activity to reduce routine chest radiograph in mechanically ventilated patients (QI project) Reduce the total dose of corticosteroids used in patients hospitalized for AECOPD (QI project) Ramirez, R Pharmacy resident Mathis, Samuel Medical Student 2011 Summer Research Training in Ageing Hijjawii, Shadi House Staff Internal Medicine Pulmonary & Critical Care Medicine Fellow Pulmonary & Critical 30-day readmission in patients hospitalized with AECOPD (Best abstract) Iatrogenic pneumothorax. A single center perspective. Outcome of HIV positive patients Meena, Regai Meena, Regai Gulshan Sharma, M.D. Sudhakar, Selvin Care Medicine Fellow House Staff Internal Medicine Allergy Immunology Fellow Cardiology Fellow Sonstein, Lindsay Faculty Sharif, Roozbeh House Staff Internal Medicine Onguti, Sharon Sokol, Kristen Almontasembellah, House Staff Internal Aljaafareh Medicine Singh, Gurinder Pulmonary Fellow Page 11 hospitalzed with PJP Outcomes of patients hospitalized with bacteremia Spirometry Trends: Use in newly diagnosed patients with asthma Validation of readmission risk score and readmission in heart failure patients at a quaternary hospital Improving Adherence for Management of Acute Exacerbation of Chronic Obstructive Pulmonary Disease Predictors of Early Readmission Among Patients Aged 40 to 64 Years Hospitalized for Chronic Obstructive Pulmonary Disease Risk of cardiovascular events after initiation of long acting bronchodilators in patients with chronic Obstructive Lung disease Trends in 30-day readmission rates in fee-forservice Medicare beneficiaries with COPD2001-2010 MPH/MS Thesis Advisor: Edwards, TQ Sharif, Roozbeh Pulmonary & Critical Care Medicine Fellow House Staff Internal Medicine Surveillance following curative intent surgery for lung cancer COPD Management: How good are we doing? Predictors of 30-day readmission in patients hospitalized with COPD MEMBERSHIP IN SCIENTIFIC SOCIETIES/PROFESSIONAL ORGANIZATIONS: Associate Member, American College of Physicians, American Society of Internal Medicine Member, American Thoracic Society Member, American College of Chest Physician Member, Association of Pulmonary & Critical Care Medicine Program Directors Member, Infectious Disease Society of America Member, Society of Critical Care Medicine Member, Academy Health Member, HIMMS HONORS: 2005 - Department of Internal Medicine Alumni-Faculty Excellence in Teaching Award 2005 - Voted ‘Teacher of the Year’ by Internal Medicine house staff 2005 - Invited to attend the “7th Leadership Development Program for Academic Physicians ACCP, Montreal Gulshan Sharma, M.D. 2006 - Present 2007 - 2013 2014 - Present 2008 - Finalist 2011 2012 2013 2013 2014 2014 Page 12 Fellow American College of Chest Physician (F.C.C.P) Fellow of the Sealy Center on Aging, UTMB, Galveston Senior Fellow of the Sealy Center on Aging, UTMB, Galveston Robert Wood Johnson Foundation – Physician Faculty Scholars Program Sealy and Smith Distinguished Chair in Internal Medicine UT System Clinical Safety and Effectiveness Fellow Best Doctors of America Texas Super Doctors, Critical Care Best Doctors of America Texas Super Doctors, Critical Care ADDITIONAL INFORMATION: Editor May 2009 – Present Core Evidence Editor-in-Chief Peer-Review Journal Reviewer JAMA Archives of Internal Medicine (JAMA Internal Medicine) Annals of Internal Medicine Am J Med J Gen. Int. Med Journal of Hospital Medicine Postgraduate Medicine Journal of Gerontology: Medical Sciences Gerontology Annals of the American Thoracic Society Respiratory Medicine Critical Care Medicine Int J Chr Obstr Pulm Dis. Clinical Nutrition Lung India The American Journal of Managed Care BMC Geriatrics Clinical Epidemiology Cancer Management and Research Clinical Medicine Reviews in Therapeutics Respirology PLoS One Grant Reviewer 2011 2014 Physicians’ Services Inc. Foundation, Toronto, Canada The University of Texas Healthcare Safety and Effectiveness Grants Program: Gulshan Sharma, M.D. Page 13 Quality of Care Research Grants BIBLIOGRAPHY (PUBLISHED): A. ARTICLES IN PEER-REVIEWED JOURNALS 1. Terminella, L., Sharma, G.: Diagnostic studies in patients with acute respiratory distress syndrome (ARDS). Semin Thorac Cardoivasc Surg. 2006; 18:2-7. PMID16766246 2. Sharma, G., Goodwin, J.: Effect of “normal” ageing on respiratory system. Clinical Intervention in Ageing 2006; 3(1):255-260. PMID 18046878 PMC2695176 3. Sharma, G., Han, L., Quagliarello, V.: Functional outcome of hospitalized elderly patients with community acquired pneumonia. Infect Dis Clin Pract.2006; 14:365-368. 4. Imad, M., Schnedig, V., Sharma, G.: A case in point: What caused this patient’s cough and hemoptysis? J Respir Dis. 2007; 28(3):109-112 5. Babu R, Sharma G. A 57-Year-Old Man with Abdominal Pain, Jaundice, and History of a Blood Transfusion." Chest. 2007;132(1):347-50 PMID 17625097 6. Babu R, Romero A, Sharma G. A 39-Year-Old Man with Epigastric Pain, Intermittent Chest Pain, and Progressive Dyspnea. Chest. 2007;132(6): 2012-2015 PMID18079237 7. Sharma, G., Freeman, J., Zhang, D., Goodwin, J. Trends in end of life care among older adults with advanced lung cancer. Chest 2008; 133: 72-78. PMID17989164 8. Babu R, Cardenas Jr. V, Sharma G. Acute Respiratory Distress Syndrome from Chlorine Inhalation during a Swimming Pool Accident: A Case Report and Review of the Literature. Journal of Intensive Care Med 2008; 23(4):275-280. PMID18508837 9. Murugan, A, Sharma, G. Obesity and lung diseases. Chron Respir Dis 2008; 5(4):233-242. PMID19029235 10. Sharma, G., Freeman, J., Zhang, D., Goodwin, J. Continuity of care and ICU utilization during end of life. Arch Intern Med. 2009;169(1) 81-86. PMID19139328 PMC2745737 11. Kuo YF, Sharma G, Freeman J, Goodwin JS. Growth of General Internal Medicine hospitalists caring for older patients in US hospitals. N Eng J Med 2009; 360:1102-12. PMID19279342 PMC2977939 12. Martinez, JD, Babu R, Sharma, G. Case Report: Escherichia coli Septic Shock Masquerading as ST-Segment Elevation Myocardial Infarction. Postgrad Med 2009; 121(2): 102-105. PMID19332967 13. Sharma G, Fletcher K, Zhang D, Kuo YF, Freeman J, Goodwin JS. Continuity of outpatient and inpatient care by primary care physicians for hospitalized older patients. JAMA 2009;301(16):1-10 PMID19383958 PMC2771916 14. Enfield K, Shim M, Sharma G. Asthma, Obesity and type 2 diabetes – mechanisms, management and prevention. Diabetes Voice 2009;54(2):30-33 15. Bhutani MS, Saftiou A, Chaya C, Gupta P, Markowitz A, Willis M, Kessel I, Sharma G, Zwischenberge JB. Irregular echogenic foci representing coagulation necrosis: a useful but under-recognized EUS echo feature of malignant lymph node invasion. J Gastrointestin Liver Dis. 2009;18(2):181-184. PMID19565048 16. Abu Said G, Tuero E, Khalife W, Paniagua O, Barbagelata A, Sharma G. Diastolic Dysfunction and COPD exacerbation Postgrad Med 2009 Jul;121(4):76-81 PMID19641273. 17. Sharma G, Hanania N, Shim MY. The aging immune system and its relationship to the Gulshan Sharma, M.D. Page 14 development of COPD. Proc Am Thorac Soc 2009 Dec 1;6(7):573-580. PMID19934352 18. Sharma G, Kuo YF, Zhang D, Freeman J, Goodwin JS. Co-management of hospitalized surgical patients by medicine physicians in the United States. Arch Intern Med. 2010 Feb 22;170(4):363-368 PMID20177040 PMC2843086 19. Chow L, Sharma G. Images in Radiology: Diabetes mellitus and confusion. Am J Med 2010 Mar;123(3):228-230 PMID20193830 20. Gopal M, Romero A, Baillargeon J, Sharma G. Trends in pleural biopsies between 1996 and 2006 at a tertiary medical center. Am J Med Sci. 2010 Apr; 339(4):345-349. PMID20228666 21. Shah S, Phan NB, Goyal G, Sharma G. Progressive Pulmonary alveolar proteinosis in a 67 year old women with Wegener’s Granulomatosis. J Gen Int Med. 2010 Oct;25(10):11051108. PMID20623200 PMC2955465 22. Sharma G, Kuo YF, Zhang D, Freeman J, Goodwin JS. Outpatient follow-up visit and 30day risk of emergency room visit and readmission in patients hospitalized for chronic obstructive pulmonary disease. Arch Intern Med. 2010 Oct;170(18):1664-1670. PMID20937926 PMC2977945 23. Hanania N, Sharma G, Sharafkhaneh, A. COPD in the Elderly patient. Semin Respir Crit Care Med. 2010 Oct;31(5):596-606. PMID20941660 24. Shah SK, Cardenas V, Kuo YF, Sharma G. Rapid Response Team in an Academic Institution-Does It Make a Difference? Chest 2011 Jun;139(6);1361-1367. PMID20864618 25. Sharma G. On being a Doctor. A Dozen eggs. Ann Intern Med. 2011 May;154:640-641 PMID21536941 26. Fletcher KE, Sharma G, Zhang D, Kuo YF, Freeman J, Goodwin JS. Trends in Inpatient Continuity of Care for a Cohort of Medicare Patients 1996-2006. J Hosp. Med. 2011 Oct; 6(8):438-44. PMID21990172 PMCID:3201736 27. Baillargeon J, Holmes HM, Lin YL, Raji MA, Sharma G, Kuo YF. Concurrent use of warfarin and antibiotics and the risk of bleeding in older adults. Am J Med. 2012; Feb;125(2):183-9 PMID:22269622 28. Shah S, Kumar S, Babu R, Sharma G, Duarte A. Management of Calcium Channel Antagonist Overdose with Hyperinsulinemia-Euglycemia Therapy: Case Reports in Critical Care Volume 2012 (2012), Article ID 927040, 5 pages,doi:10.1155/2012/927040 29. Prys-Picard C, Shah S, Williams B, Cardenas V, Sharma G. Outcomes of critically ill patients on multiple vasoactive drugs. J Intensive Care Med 2012 Jun 24 doi:085066612448738; PMID:22733722 30. Fisher SR, Kuo YF, Sharma G, Raji MA, Kumar A, Goodwin JS, Ostir GV, Ottenbacher KJ. Mobility After Hospital Discharge as a Marker for 30-Day Readmission. J Gerontol Med Sci 2013 Jul;68(7):805-10. PMID:23254776; PMCID:3674716 31. Baillargeon J, Wang Y, Kuo YF, Holmes HM, Goodwin JS, Sharma G. Temporal Trends in Hospitalization Rates for Older Adults with Chronic Obstructive Pulmonary Disease. Am J Med 2013 Jul;126(7):607-14. PMID:23688662 32. Sharif R, Cuevas C, Wang Y, Arora M, Sharma G. Guideline Adherence in Management of Stable Chronic Obstructive Pulmonary Disease. Respir Med 2013 Jul;107(7):1046-52. PMID:23639271 33. Edwards TQ, Kuo YF, Sharma G. Surveillance Following Lung Cancer Resection. Clin Res Pulmonol 2013 Aug; 1:1001 Gulshan Sharma, M.D. Page 15 34. Sharma G, Wang Y, Graham JE, Kuo YF, Goodwin JS (2013). Provider Continuity Prior to the Diagnosis of Advanced Lung Cancer and End-of-Life Care. PLoS ONE 8(9): e74690. doi:10.1371/journal.pone.0074690 35. Trikha, Anita, Tan, Alai PhD, Pierson, Karen, Sharma, G, Wilkinson, G, Bonds R. Development of food allergies in pediatric patients with Gastroesophageal Reflux Disease treated with gastric acid suppressive medications. Pediatr Allergy Immunol 2013 Aug 2. PMID23905907 36. Shawn P. E. Nishi, Yue Wang, Yong-Fang Kuo, James S. Goodwin, and Gulshan Sharma "Spirometry Use among Older Adults with Chronic Obstructive Pulmonary Disease: 1999–2008". Ann Am Thorac Soc. 2013;10(6)565-573. 37. Sharif R, Parekh T, Pierson K, Kuo YF, Sharma G. Predictors of Early Readmission Among Patients Aged 40 to 64 Years Hospitalized For Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2014; 11(5):685–694. 38. Jordan Terasaki MD, Shawn P.E. Nishi MD. Bill T. Ameredes PhD, Gulshan Sharma MD. Arformoterol: Rationale for use in Chronic Obstructive Pulmonary Disease. Clinical Investigation. 2014; 4(5):429-439. Letters: 1. Sharma G, Kuo YF. In Reply- Relapse After Hospital Admission for COPD: Are Routine Outpatient Follow-up Visits the Way to Go? Arch Intern Med. 2011;171(8):790. Book Chapters: 1. Shah S, Nishi S, Sharma G. Chronic Obstructive Pulmonary Disease in Older adults. Aging and Lung Disease: A clinical guide. Chapter 3;pages 63-89 2. Shah S, Sharma G. Current Clinical Diagnostic Tests for Asthma. Heterogeneity in Asthma. Chapter 5. Invited Commentary: Sharma G. Medical Consultation of Surgical cases in the era of value-based care. JAMA Intern Med. Published online August 04, 2014. doi:10.1001/jamainternmed.2014.1499 B. ABSTRACTS: 1. Sharma, G., Ailani, R., Kucukarsalan, S., Teague, K., Wright, D., DiGiovine, B.: Effectiveness of American Thoracic Society-inspired guidelines for inpatient management of Community Acquired Pneumonia. Am. J. Respir. Crit. Care Med. 2000; 2. Asmi, A.E., Sharma, G., Villanueva, F., Harpootlian, S., Vollman, K., DiGiovine, B., Hyzy, R.: Implementation of a ventilator pathway decreases length of mechanical ventilation in COPD patients with acute respiratory failure. Am. J. Respir. Crit. Care Med. 2000; 3. Sharma, G., Eyzaguirre, A., Yataco, J., DiGiovine, B.: Predictors of outcome in patients with culture positive empyemas (POPE study). Am. J. Respir. Crit. Care Med. 2001; Gulshan Sharma, M.D. Page 16 4. Sharma, G., Arora, S., Parambil, J.: Pleural Effusions in patients with Acquired Immunodeficiency Syndrome: Emphasis on spectrum of diseases. Chest 2001; 120 (4): 134S 5. Sharma, G., Ataya, S., Madichetty, H., Jaffery, H., DiGiovone, B.: Cytologically positive pleural effusions: Emphasis on etiology and distribution of transudates and exudates. Chest 2001; 120 (4): 194S 6. Sharma, G., Parambil, J., Arora, S., Abbas, M.: Epidemiology of pleural effusions among HIV patients in the era of highly active antiretroviral therapy. IDSA 2001 7. Sattar, F., Terminella, L., Duarte, A., Sharma, G.: Obesity hypoventilation syndrome. An under recognized entity. Chest 2005; 128 (4): 231S 8. Imad, M., Schnedig, V., Sharma, G.: Mucinous cystadenocarcinoma pulmonary tumor. Chest 2005; 128 (4): 484S 9. Sharma, G., Freeman, J., Zhang, D., Goodwin, J.: Trends in ICU utilization among patients with advanced lung cancer in last 6 months of life. Am. J. Respir. Crit. Care Med. 2006; 10. Jain, A., Imad, M., Sharma, G.: Is etomidate really a culprit in relative adrenal insufficiency in patients with septic shock? Am. J. Respir. Crit. Care Med. 2006; 11. Rastogi, S., Gupta, R., Sharma, G.: Pattern of cardiac troponin release in patients without acute coronary syndrome. Chest 2006; 130 (4): 203S 12. Babu R, Sharma G. Babesiosis: A rare and potentially fatal risk of blood transfusion. Chest 2006; 130 (4): 299S 13. Imad M, Sharma G. Ventilator associated pneumonia and mortality in mechanically ventilated obese patients. Am. J. Respir. Crit. Care Med. 2007; 14. Sharma G, Bidell E, Graves D, Odette C, Cardenas V. Impact of Rapid Response Teams on in-hospital codes. Society of Critical Care Med 2008 15. Abu Said G, Sharma G, Tuero E, Khalife W, Paniagua O, Barbagelata A. Diastolic Dysfunction is a useful marker to risk stratify patients with frequent COPD exacerbation and normal left ventricle ejection fraction. American Heart Failure Society 2008. 16. Romero A, Gopal M, Sharma G. Retrospective review of blind pleural biopsies at a tertiary medical center. Chest.2008;134(4_MeetingAbstracts):p55003. doi:10.1378/chest.134.4_MeetingAbstracts.p55003 17. Naik S, Chiarchiaro J, Sharma G. A rare and fatal case of Mycoplasma associated myocarditis. ACCP 2008 18. Sharma G, Garza-Gutierrez G, Cardenas V, Baillargeon G, Murray O, Williams B, Baillargeon J. Use of Intensive Care during the End-of-Life among a State Prison Population. ATS San Diego 2009. 19. Garza-Gutierrez, Shah S, Sharma G. Risk factors for community acquired MRSA and outcomes. ACCP San Diego 2009. (oral presentation) 20. Prys-Picard C, Williams B, Cardenas V, Sharma G. Outcomes of critically ill patients on multiple vasopressor therapy (ERS2010) 21. Mohsen N, Sharma G. Angiotensin-converting Enzyme Inhibitor And Angiotensin II Receptor Blocker-Induced Angioedema: Overuse of Ineffective Treatment. (Poster presentation Journal of Allergy and Clinical Immunology - J ALLERG CLIN IMMUNOL 01/2011; 127(2). DOI: 10.1016/j.jaci.2010.12.421 22. G Sharma, YL Lin, Y F Kuo, T Riall, J Goodwin. Trends in surveillance following lung cancer resection. ATS Denver 2011 Am J Respir Crit Care Med 183;2011:A2595 23. Hoang-Edwards TQ, Sharma G. Surveillance following curative intent surgery for nonsmall cell lung cancer. A systematic review. Chest 2011 Gulshan Sharma, M.D. Page 17 24. Ubhayaker KM, G Garza, V Cardenas, Sharma G. The effectiveness of focused educational activities on reducing the use of routine chest radiographs in mechanically ventilated patients. Chest.2011;140(4_MeetingAbstracts):329A.doi:10.1378/ chest.1111847 25. De Los Santos M, Shah S, Valentine V, Sharma G. Innocent bystander or partner in crime. Am J respire Crit Care Med 185;2012:A6117 26. De Los Santos M, Shah S, Valentine V, Sharma G. Lessons learned from a larva. Am J Respir Crit Care Med 185;2012:A5477. 27. Ramirez RL, Lee E, Clark C, Sonstein L, Sharma G. Improving Variation in Amount of Corticosteroid Used in Patients Hospitalized with Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD). AJRCCM ATS Denver 2013 28. Shah S, Farber A, Sharma G. Diagnostic tests in patients with community acquired pneumonia. Am J Respir Crit Care Med 185;2012:A1503 29. Roozbeh Sharif MD, Christel Cuevas MD, Mohit Arora MD, 1Yue Wang MS, Gulshan Sharma MD MPH. Disease Management in Ambulatory Clinics. How good are we doing? Oral presentation Chest 2012 30. Shadi B. Hijjawi, MD, Marwan Abu Minshar, MD, Yue Wang, MS, Gulshan Sharma, MD, MPH 30- day Readmissions in Patients Hospitalized with Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD). Oral presentation Chest 2012 31. Jacques Baillargeon PhD, Yue Wang MS, Yong-Fang Kuo PhD, James S. Goodwin MD, Gulshan Sharma MD, MPH. Temporal Trends in Hospitalization Rates for Older Adults with Chronic Obstructive Pulmonary Disease. Oral presentation The American Journal of Medicine, Volume 126, Issue 7, Pages 607-614 32. Nishi SP, Wang Y,Kuo YF, Goodwin JS, Sharma G. Spirometry Use In Older Adults With Chronic Obstructive Pulmonary Disease: 1999-2008. Am J Respir Crit Care Med 187;2013:A2839 33. Nishi SP, Wang Y, Kuo YF, Sharma G. Long-Term Oxygen Therapy Use In Older Adults With Chronic Obstructive Pulmonary Disease. ATS 2013 34. Meena Regai, Sharma G. Iatrogenic pneumothorax. A single center perspective. Am J Respir Crit Care Med 187;2013:A3901 35. Samuel G, Loeffelholz M, Lea Alfred S Sharma, G. Diagnosis of Respiratory Pathogens From Bronchoalveolar Fluid Using the Film Array Respiratory Panel. ICAAC 2013. 36. Nishi SPE, Mercado AC, Zhang W, Kuo YF, Sharma G. Trends in use of Pulmonary Rehabilitation among older adults with Chronic Obstructive Pulmonary Disease. Chest 10/2013; 144(4_MeetingAbstracts):786A. DOI: 10.1378/chest.1704529 37. Sudhakar S, Sharma G. Validation of Readmission Risk Score and Readmission Rate in Heart Failure Patients at a Quaternary Hospital. Circulation. 2013;128:A16883 38. Regai M, Samuel S, Sharma G. Outcome of HIV Positive Patients Hospitalized with Pneumocystis Jirovecii Pneumonia. Chest October 30 2013 39. Onguti S, Sharma G. Outcomes of patients hospitalized with staphylococcus bacteremia. Chest 2013 40. Cardenas V, Zeng L, Sharma G. Peripheral blood eosinophilia: A marker for corticosteroid responsiveness in patients with acute exacerbation of chronic obstructive pulmonary disease. Chest 10/2013;144(4_MeetingAbstracts):710A. DOI: 10.1378/chest.1704304 41. Washington TM, Zhang W, Kuo YF, Cooksley C, Sharma G. The Use of MRI in the Gulshan Sharma, M.D. Page 18 Evaluation of Breast Cancer. 2013 San Antonio Breast Cancer Symposium, December 10-14, 2013, San Antonio, Texas. Program P1-09-03; #365 42. Li Zeng, Smriti Neogi, and Jamie Rogers,Susan Seidensticker, Carlos Clark, Lindsey Sonstein, Rick Trevino, and Gulshan Sharma. Statistical Models for Hospital Readmission Prediction with Application to Chronic Obstructive Pulmonary Disease (COPD) Patients. Industrial Engineering and Operations Management (IEOM). 2014;ID037. (awarded the best track paper) 43. Gulshan Sharma, Carlos Clark, Lindsay Sonstein, Rick Trevino, Laura Grady. Use of Systems Engineering Tools and Concepts to Improve Chronic Disease Management. Industrial Engineering and Operations Management (IEOM). 2014. 44. Sharif R, Parekh T, Pierson K, Kuo YF, Sharma G. Predictors of Early Readmission Among Patients Hospitalized For Chronic Obstructive Pulmonary Disease. World Chest Conf. Madrid 2014 45. Ragai Meena, MD; Gulshan Sharma, MD, MPH; Wei Zhang; Yong-Fang Kuo, PhD; Shawn Nishi, MD; Alexander G. Duarte, MD. Burn Injury Associated With Domiciliary Oxygen Use In Patients With COPD. Am J Respir Care Med 189;2014:A3057. 46. Almotasembellah Aljaafareh MD, Jose R. Valle MD; Karen Pierson, Gulshan Sharma, MD, MPH. Risk of cardiovascular events after initiation of long acting bronchodilators in patients with Chronic Obstructive Lung disease. AM J Respir Crit Care Med 189;2014:A1122. 47. Singh G, Wei Z, Kuo YF, Sharma G. Trends in 30-day readmission rates in fee-forservice Medicare beneficiaries with COPD-2001-2010. Am JRespir Crit Care Med 189;2014:A5204. PUBLICATIONS – IN PRESS: 1. Sonstein L, Clark C, Seidensticker S, Zeng L, Sharma G. Improving Adherence for Management of Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Am J Med. 2. Shadi B. Hijjawi, MD, Marwan Abu Minshar, MD, Gulshan Sharma, MD, MPH. Chronic Obstructive Pulmonary Disease Exacerbation: A Single-Center Perspective on Hospital Readmissions. Postgrad Med. 3. Kusum S. Mathews, MD, MPH, Jose R. Valle, MD, & Gulshan Sharma, MD, MPH PNEUMONIA & TUBERCULOSIS IN PREGNANCY (Book chapter) PUBLICATIONS – SUBMITTED: 1. Parmar A, Sharma G, Lin Yu-Li, Kuo YF, Riall T, Goodwin JS. Pattern of imaging following lung cancer resection: 1992-2005. 2. Gulshan Sharma, MD, MPH; Ragai Meena, MD; James Goodwin, MD;Wei Zhang; Yong-Fang Kuo, PhD; Alexander G. Duarte, MD. Burn Injury Associated With Domiciliary Oxygen Use In Patients With COPD. Gulshan Sharma, M.D. Page 19 3. Selvin Sudhakar, MD, Wei Zhang, MS, Yong-Fang Kuo, PhD, Mohammed Algrouz, MD, Wissam Khalife, MD, Gulshan Sharma, MD, MPH. Validation of the Readmission Risk Score® in Heart Failure Patients at a Tertiary Hospital. MANUSCRIPTS IN PREPARATION: 1. Washington TM, Zhang W, Kuo YF, Cooksley C, Sharma G. The use of MRI in the Evaluation of Breast Cancer in Texas 2. Nishi SPE, Wang Y, Kuo YF, Sharma G. Oxygen Therapy Use in Older Adults with COPD. 3. Nishi SPE, Mercado AC, Zhang W, Kuo YF, Sharma G. Trends in the Use of Pulmonary Rehabilitation Among Older Adults with COPD. PAPERS AND CONTINUING EDUCATION PROGRAMS PRESENTED: Grand Rounds April 12, 2005: Oct 27, 2006: Nov 14, 2006: Mar 30, 2007: Dec 5, 2006: Nov. 4, 2007: May 15, 2009: July 17, 2009: May 20, 2010: July 1, 2010: Nov 4, 2010: June 21, 2013: Courses: “If you’re not confused, you’re not paying attention.” Department of Internal Medicine, UTMB “Smoking Cessation” Department of Internal Medicine, UTMB “Conceptual framework on Continuity of Care” Center for Population Health and Health Disparities, UTMB “Smoking Cessation”: The 14th annual Essentials in Internal Medicine: Update on Principles and Practice in conjunction with The 2007 Department of Internal Medicine Alumni Society and Scientific Meeting “Update on Hospital acquired pneumonia, Health Care associate pneumonia, and Ventilator associated Pneumonia.” Mainland Hospital, Texas City “Smoking Cessation”. Texas Academy of Internal Medicine (TAIM) meeting at Galveston, TX. “Morbidity & Mortality Conference” Department of Internal Medicine, UTMB ”Using QI tools for improving quality. Quality Improvement Symposium” Department of Internal Medicine, UTMB “Improving DVT prophylaxis rates in hospitalized patients” First annual Quality and Research Forum, Department of Internal Medicine, UTMB “Role of human error in diagnostic adverse events, Department of Internal Medicine, UTMB “Improving DVT prophylaxis rates in hospitalized patients using HIT.” UT Health Systems. Clinical Safety and Effectiveness Meeting. Austin, TX Translating Evidence in Management of COPD, UT Tyler Grand Rounds, Tyler, Texas Gulshan Sharma, M.D. Page 20 1. Sharma, G., Rochester, C.L.: Respiratory complications of obesity. PCCU, Vol. 18, Lesson 16, 2004. 2. Sharma, G.: Critical Care Journal Club, 2004. http://www.thoracic.org/assemblies/cc/ccjcframe.html 3. Sharma, G.: Airway inflammation in asthma and autoimmune disease. Facilitator ATS 2005. 4. Sharma, G.: Epidemiology and Outcomes thematic poster session. Facilitator: Society of Critical Care Medicine, Hawaii 2008. 5. Sharma, G: What’s new in Swine flu? Lead Facilitator, ATS International Conference , New Orleans, 2010. 6. Sharma, G. Fundamental Critical Care Support Course. Diagnosis and management of shock. UTMB 2/25/2012. 7. Nishi S, Sharma G. Chronic Obstructive Pulmonary Disease. First Consult contributor. 8. Sharma G. Nonresolving Pneumonia. Audio-Digest Internal Medicine (RESPIRATORY ILLNESS). 2012. Volume 59, Issue 37. 9. Sharma G. Moderator. COPD severity metrics. Chest 2013 INVITED LECTURES: May 13, 2008: April 22-23, 2009: October 15, 2010: April 14, 2011: September 20, 2011: April 14, 2012: April 18, 2012: October 9, 2012: Research Talk – “Continuity of care and end of life ICU use”. Baylor College of Medicine, Section of PCCM. IXth COPD conference in Lund, Sweden: “Development and Ageing: Relevance to COPD? Aging and immune system and its relationship to lung disease” 14th Annual Interdisciplinary Conference on Supportive Care, Hospice and Palliative Medicine, MD Anderson, Houston, TX “Overuse of care, considered aggressive during end of life” Research Conference – “Surveillance following lung cancer resection” BCM, Houston, TX The John P McGovern Academy of Oslerian Medicine - UTMB Osler Club: “Overuse of care, considered aggressive during end of life” “Non-Resolving Pneumonia”: The 18th annual Essentials in Internal Medicine: Update on Principles and Practice in conjuction with The 2012 Department of Internal Medicine Alumni Society and Scientific Meeting “Overuse of Care Considered Aggressive During End of Life” Special Topics in Geriatrics: Addressing Difficult Topics in Aging and Disease: UTMB East Texas Geriatric Education Center Consortium (ETGEC-C) in partnership with the Texas AHEC East “A Career in academic medicine” 2nd Annual Hispanic Center of Excellence Faculty Development Conference. Moody Gardens, Galveston Gulshan Sharma, M.D. May 19, 2013: May 21, 2013: June 21, 2013: August 10, 2013 August 8, 2014 Page 21 Hospital Readmissions: The next challenge in pulmonary medicine practice; “Hospitalist movement and its impact on process of care and post-discharge outcomes” American Thoracic Society, Philadelphia, PA Special Case of the Older Adult in Pulmonary and Critical Care “COPD in Older Adults” American Thoracic Society, Philadelphia, PA Translating Evidence in Management of COPD, UT Tyler Grand Rounds, Tyler, Texas “Readmissions to ICU and Hospital”; 66th Koppa Conference, Mo Ranch Conference Center, Hunt, Texas Choosing wisely: Top 5 recommendations for Pulmonary & Critical Care Medicine. 67th Koppa Conference, Mo Ranch Conference Center, Hunt, Texas
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