Mediators of Inflammation Special Issue on Inflammatory Markers and Health Status CALL FOR PAPERS Persistent, chronic low-grade systemic inflammation has been increasingly recognized as a common pathological process and an important contributing factor to chronic diseases such as hypertension, dyslipidemia, diabetes, cardiovascular diseases, cancer, dementia, and osteoporosis, many of which are age-related. Clarifying the strength of the relationship between various inflammatory markers and health status, establishing diagnostic cutoff points for levels of serum inflammatory markers, identifying inflammatory level risk factors (such as lifestyle, genetic, and environmental factors), and investigating new treatment strategies to reduce inflammatory levels in different populations are crucial steps toward providing early treatment and for disease prevention. We invite investigators to contribute original research and review articles that seek to explore the relationship between serum inflammatory markers and chronic and age-related diseases and the development of strategies to modify systemic levels of inflammatory markers in different populations. We are interested in articles that explore aspects of chronic low-grade systemic inflammation and its management in different populations. Potential topics include, but are not limited to: Recent developments in the relationship between various serum inflammatory markers and chronic or age-related diseases Identification of diagnostic cutoff points for levels of serum inflammatory marker as indicators of health status Elucidation of the influence of lifestyle, genetic, and environmental factors on inflammatory levels Development and testing of novel and effective anti-inflammatory strategies Authors can submit their manuscripts via the Manuscript Tracking System at http://mts.hindawi.com/submit/journals/mi/imhs/. Lead Guest Editor Kaijun Niu, Tianjin Medical University, Tianjin, China [email protected] Guest Editors Guowei Huang, Tianjin Medical University, Tianjin, China [email protected] Zongjian Zhu, Colorado State University, Fort Collins, USA [email protected] Ryoichi Nagatomi, Tohoku University, Sendai, Japan [email protected] Nadine L. Wicks, Douglas College, New Westminster, Canada [email protected] Manuscript Due Friday, 9 January 2015 First Round of Reviews Friday, 3 April 2015 Publication Date Friday, 29 May 2015