Curriculum Vitae PERSONAL INFORMATION Angel Concheiro WORK EXPERIENCE July 1988–Present Full Professor (Catedratico) University of Santiago de Compostela, (Spain) Teaching and Research EDUCATION AND TRAINING October 1968–June 1973 Degree in Chemistry University of Santiago de Compostela, (Spain) Chemistry October 1973–July 1976 PhD in Chemistry University of Santiago de Compostela, (Spain) Analytical Chemistry October 1978–July 1981 PhD in Pharmacy University of Santiago de Compostela, (Spain) Pharmaceutical Technology/Biopharmaceutics ADDITIONAL INFORMATION Expertise Publications Pharmaceutical Technology, Biopharmaceutics, Development of Drug Dosage Forms, Drug-Device Combination Products. A. Cambón, A. Rey-Rico, S. Barbosa, J. F. A. Soltero, S. G. Yeates, J. Brea, M.I. Loza, C. AlvarezLorenzo, A. Concheiro, P. Taboada, V. Mosquera. Poly(styrene oxide)-poly(ethylene oxide) block copolymers: From “classical” chemotherapeutic nanocarriers to active cell-response inducers. Journal of Controlled Release 167, 68-75 (2013) M. Rodríguez-Évora, R. Reyes, C. Alvarez-Lorenzo, A. Concheiro, A. Delgado, C. Évora. Bone regeneration induced by an in situ gel-forming poloxamine, bone morphogenetic protein-2 system. Journal of Biomedical Nanotechnology 10, 959-969 (2014). T. Segura, A.M. Puga, G. Burillo, J. Llovo, G. Brackman, T. Coenye, A. Concheiro, C. Alvarez-Lorenzo. Materials with fungi-bioinspired surface for efficient binding and fungi-sensitive release of antifungal agents. Biomacromolecules 15, 1860-1870 (2014). M.I. Rial-Hermida, N.M. Oliveira, A Concheiro, C Alvarez-Lorenzo, J.F. Mano. Bioinspired superamphiphobic surfaces as a tool for polymer- and solvent-independent preparation of drugloaded spherical particles. Acta Biomaterialia 10, 4314-4322 (2014). M.A. Luna-Straffon, A. Contreras-García, G. Brackman, T. Coenye, A. Concheiro, C. Alvarez-Lorenzo, E. Bucio. Wound debridement and antibiofilm properties of gamma-ray DMAEMA-grafted onto cotton gauzes. Cellulose 21, 3767-3779 (2014). Title: Cytocompatibility and P-glycoprotein Inhibition of Block Copolymers: Structure-Activity Relationship Author(s): Cambon, A.; Brea, J.; Loza, M. I.; et al. Source: MOLECULAR PHARMACEUTICS Volume: 10 Issue: 8 Pages: 3232-3241 DOI: 10.1021/mp4002848 Published: AUG 2013 Title: Edible chitosan/acetylated monoglyceride films for prolonged release of vitamin E and antioxidant activity Author(s): Blanco-Fernandez, Barbara; Isabel Rial-Hermida, Maria; Alvarez-Lorenzo, Carmen; et al. 30/1/15 © European Union, 2002-2014 | http://europass.cedefop.europa.eu Page 1 / 6 Curriculum Vitae Angel Concheiro Source: JOURNAL OF APPLIED POLYMER SCIENCE Volume: 129 Issue: 2 Special Issue: SI Pages: 626-635 DOI: 10.1002/app.38766 Published: JUL 15 2013 Title: Poloxamine-Cyclodextrin-Simvastatin Supramolecular Systems Promote Osteoblast Differentiation of Mesenchymal Stem Cells Author(s): Simoes, Susana M. N.; Veiga, Francisco; Torres-Labandeira, Juan J.; et al. Source: MACROMOLECULAR BIOSCIENCE Volume: 13 Issue: 6 Pages: 723-734 DOI: 10.1002/mabi.201300017 Published: JUN 2013 0 Title: Immobilization of liposomes on temperature-responsive polymer networks cross-linked with polyL-lysine and grafted onto polypropylene Author(s): Garcia-Uriostegui, Lorena; Burillo, Guillermina; Concheiro, Angel; et al. Source: DESIGNED MONOMERS AND POLYMERS Volume: 16 Issue: 3 Pages: 241-249 DOI: 10.1080/15685551.2012.725215 Published: MAY 1 2013 Title: Poly(styrene oxide)-poly(ethylene oxide) block copolymers: From "classical" chemotherapeutic nanocarriers to active cell-response inducers Author(s): Cambon, A.; Rey-Rico, A.; Barbosa, S.; et al. Source: JOURNAL OF CONTROLLED RELEASE Volume: 167 Issue: 1 Pages: 68-75 DOI: 10.1016/j.jconrel.2013.01.010 Published: APR 10 2013 Title: beta-Cyclodextrin hydrogels for the ocular release of antibacterial thiosemicarbazones Author(s): Glisoni, Romina J.; Garcia-Fernandez, Maria J.; Pino, Marylu; et al. Source: CARBOHYDRATE POLYMERS Volume: 93 Issue: 2 Pages: 449-457 DOI: 10.1016/j.carbpol.2012.12.033 Published: APR 2 2013 0 Title: Doxorubicin-loaded micelles of reverse poly(butylene oxide)-poly(ethylene oxide)-poly(butylene oxide) block copolymers as efficient "active" chemotherapeutic agents Author(s): Cambon, A.; Rey-Rico, A.; Mistry, D.; et al. Source: INTERNATIONAL JOURNAL OF PHARMACEUTICS Volume: 445 Issue: 1-2 Pages: 47-57 DOI: 10.1016/j.ijpharm.2013.01.056 Published: MAR 10 2013 Title: Poloxamine micellar solubilization of alpha-tocopherol for topical ocular treatment Author(s): Ribeiro, Andreza; Sandez-Macho, Isabel; Casas, Matilde; et al. Source: COLLOIDS AND SURFACES B-BIOINTERFACES Volume: 103 Pages: 550-557 DOI: 10.1016/j.colsurfb.2012.10.055 Published: MAR 1 2013 Title: Wound dressings loaded with an anti-inflammatory juca (Libidibia ferrea) extract using supercritical carbon dioxide technology Author(s): Dias, A. M. A.; Rey-Rico, A.; Oliveira, R. A.; et al. Source: JOURNAL OF SUPERCRITICAL FLUIDS Volume: 74 Pages: 34-45 DOI: 10.1016/j.supflu.2012.12.007 Published: FEB 2013 Title: Dexamethasone eye drops containing gamma-cyclodextrin-based nanogels Author(s): Moya-Ortega, Maria D.; Alves, Tiago F. G.; Alvarez-Lorenzo, Carmen; et al. Source: INTERNATIONAL JOURNAL OF PHARMACEUTICS Volume: 441 Issue: 1-2 Pages: 507515 DOI: 10.1016/j.ijpharm.2012.11.002 Published: JAN 30 2013 Title: Radiation grafting of glycidyl methacrylate onto cotton gauzes for functionalization with cyclodextrins and elution of antimicrobial agents Author(s): Hiriart-Ramirez, Erick; Contreras-Garcia, Angel; Jose Garcia-Fernandez, Maria; et al. Source: CELLULOSE Volume: 19 Issue: 6 Pages: 2165-2177 DOI: 10.1007/s10570-012-9782-5 Published: DEC 2012 Title: Poly(ethylene oxide)-poly(styrene oxide)-poly(ethylene oxide) copolymers: Micellization, drug solubilization, and gelling features Author(s): Cambon, Adriana; Barbosa, Silvia; Rey-Rico, Ana; et al. Source: JOURNAL OF COLLOID AND INTERFACE SCIENCE Volume: 387 Pages: 275-284 DOI: 10.1016/j.jcis.2012.06.090 Published: DEC 1 2012 Title: Antifouling foldable acrylic IOLs loaded with norfloxacin by aqueous soaking and by supercritical carbon dioxide technology Author(s): Gonzalez-Chomon, Clara; Braga, Mara E. M.; de Sousa, Herminio C.; et al. 30/1/15 © European Union, 2002-2014 | http://europass.cedefop.europa.eu Page 2 / 6 Curriculum Vitae Angel Concheiro Source: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Volume: 82 Issue: 2 Pages: 383-391 DOI: 10.1016/j.ejpb.2012.07.007 Published: OCT 2012 Title: Single and mixed poloxamine micelles as nanocarriers for solubilization and sustained release of ethoxzolamide for topical glaucoma therapy Author(s): Ribeiro, Andreza; Sosnik, Alejandro; Chiappetta, Diego A.; et al. Source: JOURNAL OF THE ROYAL SOCIETY INTERFACE Volume: 9 Issue: 74 Pages: 2059-2069 DOI: 10.1098/rsif.2012.0102 Published: SEP 7 2012 Title: Poly-epsilon-caprolactone/poloxamine matrices for drug delivery and bone regeneration applications Author(s): Puga, A. M.; Rey-Rico, A.; Alvarez-Lorenzo, C.; et al. Source: JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE Volume: 6 Special Issue: SI Supplement: 1 Pages: 326-326 Published: SEP 2012 Title: Cyclodextrin-based nanogels for pharmaceutical and biomedical applications Author(s): Moya-Ortega, Maria D.; Alvarez-Lorenzo, Carmen; Concheiro, Angel; et al. Source: INTERNATIONAL JOURNAL OF PHARMACEUTICS Volume: 428 Issue: 1-2 Pages: 152163 DOI: 10.1016/j.ijpharm.2012.02.038 Published: MAY 30 2012 Title: Loading and Release of Drugs from Oxygen-rich Plasma Polymer Coatings Author(s): Jose Garcia-Fernandez, Maria; Martinez-Calvo, Laura; Ruiz, Juan-Carlos; et al. Source: PLASMA PROCESSES AND POLYMERS Volume: 9 Issue: 5 Pages: 540-549 DOI: 10.1002/ppap.201100192 Published: MAY 2012 Title: Temperature- and pH-sensitive interpenetrating polymer networks grafted on PP: Cross-linking irradiation dose as a critical variable for the performance as vancomycin-eluting systems Author(s): Munoz-Munoz, Franklin; Ruiz, Juan-Carlos; Alvarez-Lorenzo, Carmen; et al. Source: RADIATION PHYSICS AND CHEMISTRY Volume: 81 Issue: 5 Pages: 531-540 DOI: 10.1016/j.radphyschem.2012.01.007 Published: MAY 2012 Title: Hydrophilic acrylic hydrogels with built-in or pendant cyclodextrins for delivery of anti-glaucoma drugs Author(s): Ribeiro, Andreza; Veiga, Francisco; Santos, Delfim; et al. Source: CARBOHYDRATE POLYMERS Volume: 88 Issue: 3 Pages: 977-985 DOI: 10.1016/j.carbpol.2012.01.053 Published: APR 15 2012 Title: Cytocompatibility and P-glycoprotein Inhibition of Block Copolymers: Structure-Activity Relationship Author(s): Cambon, A.; Brea, J.; Loza, M. I.; et al. Source: MOLECULAR PHARMACEUTICS Volume: 10 Issue: 8 Pages: 3232-3241 DOI: 10.1021/mp4002848 Published: AUG 2013 Title: Antiseptic cyclodextrin-functionalized hydrogels and gauzes for loading and delivery of benzalkonium chloride Author(s): Jose Garcia-Fernandez, Maria; Brackman, Gilles; Coenye, Tom; et al. Source: BIOFOULING Volume: 29 Issue: 3 Pages: 261-271 DOI: 10.1080/08927014.2013.765947 Published: 2013 Title: Hot melt poly-epsilon-caprolactone/poloxamine implantable matrices for sustained delivery of ciprofloxacin Author(s): Puga, Ana M.; Rey-Rico, Ana; Magarinos, Beatriz; et al. Source: ACTA BIOMATERIALIA Volume: 8 Issue: 4 Pages: 1507-1518 DOI: 10.1016/j.actbio.2011.12.020 Published: APR 2012 Title: Antiviral Properties of Polymeric Aziridine- and Biguanide-Modified Core-Shell Magnetic Nanoparticles Author(s): Bromberg, Lev; Bromberg, Daniel J.; Hatton, T. Alan; et al. Source: LANGMUIR Volume: 28 Issue: 9 Pages: 4548-4558 DOI: 10.1021/la205127x Published: MAR 6 2012 Title: Cross-linked hydroxypropyl-beta-cyclodextrin and gamma-cyclodextrin nanogels for drug delivery: Physicochemical and loading/release properties 30/1/15 © European Union, 2002-2014 | http://europass.cedefop.europa.eu Page 3 / 6 Curriculum Vitae Angel Concheiro Author(s): Moya-Ortega, Maria D.; Alvarez-Lorenzo, Carmen; Sigurdsson, Hakon H.; et al. Source: CARBOHYDRATE POLYMERS Volume: 87 Issue: 3 Pages: 2344-2351 DOI: 10.1016/j.carbpol.2011.11.005 Published: FEB 14 2012 Title: Syringeable Pluronic-alpha-cyclodextrin supramolecular gels for sustained delivery of vancomycin Author(s): Simoes, S. M. N.; Veiga, F.; Torres-Labandeira, J. J.; et al. Source: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Volume: 80 Issue: 1 Pages: 103-112 DOI: 10.1016/j.ejpb.2011.09.017 Published: JAN 2012 Title: Radiation-grafting of 2-hydroxyethylmethacrylate and oligo (ethylene glycol) methyl ether methacrylate onto polypropylene films by one step method Author(s): Ramirez-Jimenez, Alejandro; Alvarez-Lorenzo, Carmen; Concheiro, Angel; et al. Source: RADIATION PHYSICS AND CHEMISTRY Volume: 81 Issue: 1 Pages: 27-32 DOI: 10.1016/j.radphyschem.2011.09.002 Published: JAN 2012 Title: Drug-Eluting Intraocular Lenses Author(s): Gonzalez-Chomon, Clara; Concheiro, Angel; Alvarez-Lorenzo, Carmen Source: MATERIALS Volume: 4 Issue: 11 Pages: 1927-1940 DOI: 10.3390/ma4111927 Published: NOV 2011 Title: Receptor-based biomimetic NVP/DMA contact lenses for loading/eluting carbonic anhydrase inhibitors Author(s): Ribeiro, Andreza; Veiga, Francisco; Santos, Delfim; et al. Source: JOURNAL OF MEMBRANE SCIENCE Volume: 383 Issue: 1-2 Pages: 60-69 DOI: 10.1016/j.memsci.2011.08.030 Published: NOV 1 2011 Title: Timolol-Imprinted Soft Contact Lenses: Influence of the Template: Functional Monomer Ratio and the Hydrogel Thickness Author(s): Yanez, Fernando; Chauhan, Anuj; Concheiro, Angel; et al. Source: JOURNAL OF APPLIED POLYMER SCIENCE Volume: 122 Issue: 2 Pages: 1333-1340 DOI: 10.1002/app.34022 Published: OCT 15 2011 Title: Surface functionalization of polypropylene devices with hemocompatible DMAAm and NIPAAm grafts for norfloxacin sustained release Author(s): Contreras-Garcia, Angel; Bucio, Emilio; Concheiro, Angel; et al. Source: JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS Volume: 26 Issue: 4 Pages: 405-419 DOI: 10.1177/0883911511407788 Published: JUL 2011 Title: PEO-PPO Block Copolymers for Passive Micellar Targeting and Overcoming Multidrug Resistance in Cancer Therapy Author(s): Alvarez-Lorenzo, C.; Sosnik, A.; Concheiro, A. Source: CURRENT DRUG TARGETS Volume: 12 Issue: 8 Pages: 1112-1130 Published: JUL 2011 Title: Synergistic performance of cyclodextrin-agar hydrogels for ciprofloxacin delivery and antimicrobial effect Author(s): Blanco-Fernandez, Barbara; Lopez-Viota, Margarita; Concheiro, Angel; et al. Source: CARBOHYDRATE POLYMERS Volume: 85 Issue: 4 Pages: 765-774 DOI: 10.1016/j.carbpol.2011.03.042 Published: JUL 1 2011 Title: Bioinspired Imprinted PHEMA-Hydrogels for Ocular Delivery of Carbonic Anhydrase Inhibitor Drugs Author(s): Ribeiro, Andreza; Veiga, Francisco; Santos, Delfim; et al. Source: BIOMACROMOLECULES Volume: 12 Issue: 3 Pages: 701-709 DOI: 10.1021/bm101562v Published: MAR 2011 Title: Stimuli-responsive networks grafted onto polypropylene for the sustained delivery of NSAIDs Author(s): Contreras-Garcia, Angel; Alvarez-Lorenzo, Carmen; Taboada, Cristina; et al. Source: ACTA BIOMATERIALIA Volume: 7 Issue: 3 Pages: 996-1008 DOI: 10.1016/j.actbio.2010.10.001 Published: MAR 2011 Title: Bactericidal Core-Shell Paramagnetic Nanoparticles Functionalized with Poly(hexamethylene biguanide) 30/1/15 © European Union, 2002-2014 | http://europass.cedefop.europa.eu Page 4 / 6 Curriculum Vitae Angel Concheiro Author(s): Bromberg, Lev; Chang, Emily P.; Hatton, T. Alan; et al. Source: LANGMUIR Volume: 27 Issue: 1 Pages: 420-429 DOI: 10.1021/la1039909 Published: JAN 4 2011 Title: Biofilm inhibition and drug-eluting properties of novel DMAEMA-modified polyethylene and silicone rubber surfaces Author(s): Contreras-Garcia, Angel; Bucio, Emilio; Brackman, Gilles; et al. Source: BIOFOULING Volume: 27 Issue: 2 Pages: 123-135 Article Number: PII 931892261 DOI: 10.1080/08927014.2010.548115 Published: 2011 Title: OSTEOGENIC EFFICIENCY OF IN SITU GELLING POLOXAMINE SYSTEMS WITH AND WITHOUT BONE MORPHOGENETIC PROTEIN-2 Author(s): Rey-Rico, Ana; Silva, Maite; Couceiro, Jose; et al. Source: EUROPEAN CELLS & MATERIALS Volume: 21 Pages: 317-340 Published: JAN-JUN 2011 Title: Supercritical fluid-assisted preparation of imprinted contact lenses for drug delivery Author(s): Yanez, Fernando; Martikainen, Lahja; Braga, Mara E. M.; et al. Source: ACTA BIOMATERIALIA Volume: 7 Issue: 3 Pages: 1019-1030 DOI: 10.1016/j.actbio.2010.10.003 Published: MAR 2011 Title: To Remove or Not to Remove? The Challenge of Extracting the Template to Make the Cavities Available in Molecularly Imprinted Polymers (MIPs) Author(s): Lorenzo, Rosa A.; Carro, Antonia M.; Alvarez-Lorenzo, Carmen; et al. Source: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Volume: 12 Issue: 7 Pages: 4327-4347 DOI: 10.3390/ijms12074327 Published: JUL 2011 Projects Patents Alvarez-Lorenzo, C., Rodríguez-Tenreiro Sanchez, C., Torres Labandeira, J.J. y Concheiro Nine, A. Procedimiento de obtención de hidrogeles de ciclodextrinas con glicidiléteres, las composiciones obtenidas y sus aplicaciones. P200500556 (WO2006/089993 A2) N. patent: 2310948 Spain Alvarez-Lorenzo, C., Concheiro Nine, A., Mayo Pedrosa, M., Barreiro Iglesias, R. y Martínez Pacheco, R. Procedimiento de recubrimiento de núcleos sólidos por fotopolimerización in situ de monómeros. P200600757, ES 2285931 Spain Alvarez-Lorenzo, C., Rosa dos Santos, J.F., Torres-Labandeira, J.J., Concheiro Nine, A. Hidrogeles acrílicos con ciclodextrinas colgantes, su preparación y su aplicación como sistemas de liberación y componentes de lentes de contacto. P200802364. N. patent: ES2 335958 Spain Rey Rico, A., Puga Jiménez de Azcárate, A., Alvarez-Lorenzo, C., Concheiro Nine, A., Couceiro Follente, J. Sistema para la administración de sustancias biológicamente activas que comprende poli-caprolactona, poloxamina y una o varias sustancias activas. P200902039 N. patent: ES 2358403 Spain Alvarez-Lorenzo, C., Rey Rico, A., Silva Rivera, M., Couceiro Follente, J., Concheiro Nine, A. Uso de poloxaminas como inductoras de la diferenciación osteogénica de células mesenquimales. P201000670,PCT/ES2011/070348, WO/2011/144785, Spain. Alvarez-Lorenzo, C., Concheiro Nine, A., Moya Ortega, M.D.; Loftsson, T. Nanogeles de ciclodextrinas. P201131575 N. patent: ES 2371898 B2 Spain Muñoz Muñoz, F., Bucio Carrillo, E., Alvarez-Lorenzo, C., Concheiro Nine, A. Modificación de poliuretano con polímeros sensibles a estímulos biocompatibles para carga y cesión de fármacos. P201231908 Spain Alvarez-Lorenzo, C., Concheiro Nine, A., Simoes, S., Veiga, F. Hidrogeles de poloxamina y su uso para la regeneración o reparación ósea. P201330135 Spain Segura, T., Burillo, G., Puga Giménez de Azcárate, A.M., Alvarez-Lorenzo, C., Concheiro Nine, A. Sistemas antifúngicos bioinspirados. P201330893 Spain Memberships 30/1/15 Member of the Spanish Society of Pharmaceutics and Pharmaceutical Technology. © European Union, 2002-2014 | http://europass.cedefop.europa.eu Page 5 / 6 Curriculum Vitae Angel Concheiro Other Relevant Information 30/1/15 © European Union, 2002-2014 | http://europass.cedefop.europa.eu Page 6 / 6