EUROTHERM3235 trial newsletter issue: 22 S e pte r2 mbe 01 4 350th Patient Prize awarded – WGH 46 sites have now randomised a The 350th patient was randomised at the Western General Hospital, Edinburgh! Thank you to all the staff, a small prize has been awarded. 10 or more patients randomised are listed Recruitment Update A total of 378 patients have now been recruited to the trial! 700 700 600 600 Number of of Patients Patients Number 500 500 400 400 Predicted Predicted Recruitment Recruitment Actual Actual Recruitment Recruitment 300 300 200 200 May-16 May-16 Jan-16 Jan-16 Sep-15 Sep-15 Jan-15 Jan-15 May-15 May-15 Sep-14 Sep-14 Jan-14 Jan-14 May-14 May-14 Sep-13 Sep-13 Jan-13 Jan-13 May-13 May-13 Sep-12 Sep-12 Jan-12 Jan-12 May-12 May-12 Sep-11 Sep-11 00 May-11 May-11 100 100 Months Months 400th Patient Thank you to all sites for randomising patients over the past few months. We are approaching another milestone in the trial! We will offer a prize to the site that recruits the 400th patient! More details to follow. Team News We would like to thank Corrie Roberts for all her work on the Trial in the past year. We wish her well for the future. Welcome back Louise Sinclair, Trial Manager who returned to the Trial in August after maternity leave. patient. The highest recruiting centres with below: City, Country No. Randomised (1st Sept 2014) Western General Hospital, Edinburgh................... 41 All India Institute of Medical Services, New Dheli....... 37 King’s College Hospital, London.......................... 30 Hospital Erasme, Brussels.................................... 27 North Estonia Medical Centre, Tallin...................... 19 University Hospital of Wales, Cardiff..................... 19 Derriford Hospital, Plymouth................................. 16 Salford Royal NHS Foundation Trust, Salford........ 13 Royal Victoria Infirmary, Newcastle........................ 12 University Hospital of North Staffordshire, Stoke on Trent....................................................... 12 Complejo Universitario Asistencial de Burgos, Spain...12 Cork University Hospital, Cork.............................. 10 General University Hospital of Larissa, Greece..... 10 Recruitment at all centres is important to the trial. In addition to the top 10 centres, the centres below have recruited patients in support of the trial. City, Country No. Randomised (1st Sept 2014) London (St Mary’s), UK.......................................... 8 Rotterdam, Netherlands......................................... 8 Belfast, UK............................................................. 7 Hull, UK.................................................................. 6 Leeds, UK.............................................................. 6 London (Royal London), UK.................................. 6 Aberdeen, UK........................................................ 5 Hungary, Szeged................................................... 5 Attica, Greece........................................................ 5 Brussels (Jette), Belgium....................................... 5 Yvoir, Belgium........................................................ 5 Preston, UK............................................................ 5 Athens (Evangelismos) Greece............................. 4 Oporto, Portugal.................................................... 4 Charleroi, Belgium................................................. 4 Milan, Italy.............................................................. 4 Romford, UK.......................................................... 4 London (Charing Cross), UK................................. 3 Sheffield, UK.......................................................... 3 Athens (Gennimatas), Greece............................... 3 Riyadh, Saudi Arabia.............................................. 3 Halle, Germany...................................................... 2 Arlon, Belgium....................................................... 2 Rome, Italy............................................................. 2 Kavala, Greece...................................................... 2 Abu Dhabi, UAE..................................................... 2 Reading, UK.......................................................... 1 Brighton, UK.......................................................... 1 Moscow, Russia.................................................... 1 Liege, Belgium....................................................... 1 Ioannina, Greece................................................... 1 Coventry, UK.......................................................... 1 Madrid, Spain........................................................ 1 EUROTHERM3235 trial newsletter issue 22 Welcome on board Co-enrolment We are pleased to welcome two new sites to the Trial: Queen’s Medical Centre, Nottingham and The Walton Centre, Liverpool. Co-enrolment agreements have been set up with several other trials. Please make sure that a coenrolment agreement is in place before recruiting patients to more than one study. Site Feature Please let Trial Managers know if a patient is co-enrolled. Queen’s Medical Centre, Nottingham “Greetings from Queens Medical Centre, Nottingham! Our research team is a bit different to most others in the trust. We run both Critical Care and Emergency Department research trials as one team over a seven day rota. Due to the similar research challenges we face, we work exceptionally well together and the trials complement each other in terms of the skills and knowledge required. At QMC we are part of Nottingham University Hospitals NHS Trust. We are the tertiary Major Trauma Centre for the East Midlands and are the regional centre for a number of specialties e.g. Neurosurgery. We are the fourth largest acute teaching trust in the UK providing services to approximately 2.5 million people within the East Midlands. We employ around 13,000 staff, have 1700 beds across 87 wards and have a total of 65 adult ICU/HDU beds across 4 units. We are looking forward to joining the Eurotherm3235 Team and contributing to this important study.” Upcoming Meetings DMC The DMC will next meet in October. Please therefore ensure that all data are completed for your site The Trial Managers will contact you if there are any data queries. Contact Details • The European Society of Intensive Care Medicine (ESICM) 27th Annual Congress of the Society 29th September- 1st October. Professor Peter Andrews will be attending. Eurotherm Trial Office University of Edinburgh 2nd Floor Outpatient Building Western General Hospital Edinburgh EH 4 2XU Website: www.eurotherm3235trial.eu Email: [email protected] TEL: +44131 537 1131 (Office Hours) Mobile: + 44 7834416962 (Out of hours) • 2nd AIIMS ANNUAL NEUROTRAUMA CONFERENCE: 31st October - 2nd November 2014, New Delhi, India. Professor Peter Andrews will be speaking. The Eurotherm3235trial is funded by the National Institute for Health Research’s Health Technology Assessment Programme • The Society of British Neurological Surgeons (SBNS) Autumn meeting - 17th-19th September. Jonathan Rhodes and Claire Battison will be attending this meeting. Please stop by and visit the Eurotherm table if you are attending. Thank you to all sites for supporting the Eurotherm Trial. If any new sites are interested in joining the Trial please get in touch with the Trial Team for further information.