PAP の発現とその経緯

Figure Supplemental Digital Content 1
% cell viability
Panc-1
120
AZD6244 (MEK-I)
100
BEZ235 (PI3K-I)
80
60
40
20
0
0
0.001
0.01
0.1
1
Drug concentration (μM)
Effects of MEK inhibitor AZD6244 or the PI3K inhibitor BEZ235 on the viability of Panc1 cells. Cell viability was markedly reduced by BEZ235
and mildly reduced by AZD 6244.