Cox mAB 31A2 Enteroviruses, including coxsackie B viruses (CVB) have been associated with the development of meningitis, diabetes type 1 and severe forms of acute and chronic myocarditis (inflammatory cardiomyopathy). The monoclonal antibody Cox mAB 31A2 was developed in order to overcome constant problems of virus protein VP1 detection in immunohistochemistry (Curr Diab Rep (2010) 10:350-356; Med Microbiol Immunol (2004) 193:101–107). The antibody reacts specifically with CVB3. Detection of CVB3 VP1 in human cardiomyocytes (lethal myocarditis in a neonate) Detection of CVB3 VP1 in murine cardiomyoctes x400 x400 Immunohistochemistry mAB 31A2 x600 Immunohistochemistry mAB 31A2 x200 Negative control Immunofluorescence mAB 31A2 x400 Negative control Pictures courtesy of Prof. Dr. K. Klingel Dep. of Molecular Pathology, University of Tübingen, Tübingen, Germany Detection of CVB3 VP1 in murine exocrine pancreatic cells x200 x500 Immunohistochemistry mAB 31A2 SDS PAGE Western Blot reduced non reduced 3 different mAB preparations Mediagnost Gesellschaft für Forschung und Herstellung von Diagnostika GmbH Aspenhaustr 25 72770 Reutlingen Deutschland +49 7121 51 4840 - www.mediagnost.de - [email protected] Mouse anti-Coxsackievirus B3 Monoclonal Antibody 31A2 Catalog ID: M47 Target: Coxsackievirus B3, VP1 Host species: mouse Class: monoclonal Clone: 31A2 Isotype: IgG2a Specific reactivity: human, mouse Specificity: Coxsackievirus B3 Cross reactivity: none with Coxsackievirus B2, Coxsackievirus B4, Coxsackievirus B5, Coxsackievirus A9, Echovirus 7 Reagent provided: 100µL in PBS pH7.2, 0,01% sodium azide, stabilizing proteins have been added Application: Immunohistochemistry / Immunofluorescence in frozen and formalin-fixed embedded tissues, Cell Culture, Western Blot, ELISA, FACS Dilutions for applications: Immunohistochemistry / Immunofluorescence 1: 500, Western Blot 1: 500- 1: 1000 Storage: 4°C, long term storage at -20°C avoid repeated thaw freeze cycles Product is for In-Vitro and Research Use Only. Not for Use in diagnostic procedures. Mediagnost Gesellschaft für Forschung und Herstellung von Diagnostika GmbH Aspenhaustr 25 72770 Reutlingen Deutschland +49 7121 51 4840 - www.mediagnost.de - [email protected]
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