Publikationen Seite 1/19 Publikationen 2015 Boettcher B, Palige K, Jacobs en ID, Hube B, Brunke S (2015) Cs r1/Zap1 Maintains Zinc Homeos tas is and Influences Virulence in Candida dubliniens is but Is Not Coupled to Morphogenes is . Eukaryot Cell 14: 661-670 Brandes S, Mokhtari Z, Es s ig F, Hunniger K, Kurzai O, Figge MT (2015) Automated s egmentation and tracking of non-rigid objects in time-laps e micros copy videos of polymorphonuclear neutrophils . Med Image Anal 10.1016/j.media.2014.10.002 Brunke S, Quintin J, Kas per L, Jacobs en ID, Richter ME, Hiller E, Schwarzmuller T, d'Enfert C, Kuchler K, Rupp S, Hube B, Ferrandon D (2015) Of mice, flies - and men? Comparing fungal infection models for large-s cale s creening efforts . Disease Models & Mechanisms 10.1242/dmm.019901 Bruns T, Lutz P, Stallmach A, Nis chalke HD (2015) Low as citic fluid protein does not indicate an increas ed ris k for s pontaneous bacterial peritonitis in current cohorts . J Hepatol 10.1016/j.jhep.2015.03.040 Bruns T, Zimmermann HW, Pachnio A, Li KK, Trivedi PJ, Reynolds G, Hubs cher S, Stamataki Z, Badenhors PW, Wes ton CJ, Mos s PA, Adams DH (2015) CMV Infection of Human Sinus oidal Endothelium Regulates Hepatic T Cell Recruitment and Activation. J Hepatol 10.1016/j.jhep.2015.02.046 Cambau E, Bauer M (2015) Multi-pathogen real-time PCR s ys tem adds benefit for my patients : yes . Intensive Care Med 41: 528-530 Duggan S, Leonhardt I, Huenniger K, Kurzai O (2015) Hos t res pons e to Candida albicans bloods tream infection and s eps is . Virulence 6: 316-326 Ekaney ML, Bockmeyer CL, Sos s dorf M, Reuken PA, Conradi F, Schuerholz T, Blaes s MF, Friedman SL, Los che W, Bauer M, Claus RA (2015) Pres erved expres s ion of mRNA coding von Willebrand factor-cleaving proteas e, ADAMTS13 by s elenite and activated protein C. Molecular medicine 10.2119/molmed.2014.00202 Gabrielli E, Pericolini E, Luciano E, Sabbatini S, Ros elletti E, Perito S, Kas per L, Hube B, Vecchiarelli A (2015) Induction of Cas pas e-11 by As partyl Proteinas es of Candida albicans and Implication in Promoting Inflammatory Res pons e. Infection and immunity 83: 1940-1948 Geis C, Ritter C, Rus chil C, Weis haupt A, Grunewald B, Stoll G, Holmoy T, Mis u T, Fujihara K, Hemmer B, Stadelmann C, Bennett JL, Sommer C, Toyka KV (2015) The intrins ic pathogenic role of autoantibodies to aquaporin 4 mediating s pinal cord dis eas e in a rat pas s ive-trans fer model. Exp Neurol 265: 8-21 Goeb E, Reymann S, Langhaus er F, Schuhmann MK, Kraft P, Thielmann I, Goebel K, Brede M, Homola G, Solymos i L, Stoll G, Geis C, Meuth SG, Nies wandt B, Kleins chnitz C (2015) Blocking of Plas ma Kallikrein Ameliorates Stroke by Reducing Thromboinflammation. Ann Neurol 77: 784-803 Götz T, Milde T, Curio G, Debener S, Lehmann T, Leis tritz L, Witte OW, Witte H, Haueis en J (2015) Primary s omatos ens ory contextual modulation is encoded by os cillation frequency change. Clinical Neurophysiology 10.1016/j.clinph.2014.12.028 Gros s e C, Bergner N, Dellith J, Heller R, Bauer M, Mellmann A, Popp J, Neugebauer U (2015) Label-free imaging and s pectros copic analys is of intracellular bacterial infections . Analytical Chemistry 87: 2137-2142 Hagel S, Reis chke J, Kes s elmeier M, Winning J, Gas tmeier P, Brunkhors t FM, Scherag A, Pletz MW (2015) Quantifying the Hawthorne Effect in Hand Hygiene Compliance Through Comparing Direct Obs ervation With Automated Hand Hygiene Monitoring. Infection Control and Hospital Epidemiology 10.1017/ice.2015.93: 1-6 Hartog CS, Benbenis hty J (2015) Unders tanding nurs e-phys ician conflicts in the ICU. Intensive Care Med 10.1007/s 00134-014-3517-z Hartog CS, Schwarzkopf D, Riedemann NC, Pfeifer R, Guenther A, Egerland K, Sprung CL, Hoyer H, Gens ichen J, Reinhart K (2015) End-of-life care in the intens ive care unit: A patient-bas ed ques tionnaire of intens ive care unit s taff perception and relatives ' ps ychological res pons e. Palliat Med 29: 336-345 Has elmann H, Ropke L, Werner C, Kunze A, Geis C (2015) Interactions of Human Autoantibodies with Hippocampal GABAergic Synaptic Trans mis s ion - Analyzing Antibody-Induced Effects ex vivo. Front Neurol 6: 136-136 Heinekamp T, Schmidt H, Lapp K, Pahtz V, Shopova I, Kos ter-Eis erfunke N, Kruger T, Kniemeyer O, Brakhage AA (2015) Interference of As pergillus fumigatus with the immune res pons e. Seminars in Immunopathology 37: 141-152 Hube B, Hay R, Bras ch J, Veraldi S, Schaller M (2015) Dermatomycos es and inflammation: The adaptive balance between growth, damage, and s urvival. J Myc Med 25: E44-E58 Huenniger K, Bieber K, Martin R, Lehnert T, Figge MT, Loeffler J, Guo R-F, Riedemann NC, Kurzai O (2015) A http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 2/19 Second Stimulus Required for Enhanced Antifungal Activity of Human Neutrophils in Blood Is Provided by Anaphylatoxin C5a. J Immunol 194: 1199-1210 Joynt GM, Lipman J, Hartog C, Guidet B, Paruk F, Feldman C, Kis s oon N, Sprung CL (2015) The Durban World Congres s Ethics Round Table IV: health care profes s ional end-of-life decis ion making. J Crit Care 30: 224230 Karch A, Cas tell S, Schwab F, Geffers C, Bongartz H, Brunkhors t FM, Gas tmeier P, Mikolajczyk RT (2015) Propos ing an empirically jus tified reference thres hold for blood culture s ampling rates in intens ive care units . Journal of Clinical Microbiology 53: 648-652 Klinger-Strobel M, Lautens chlager C, Fis cher D, Mainz JG, Bruns T, Tuchs cherr L, Pletz MW, Makarewicz O (2015) As pects of pulmonary drug delivery s trategies for infections in cys tic fibros is - where do we s tand? Expert Opinion on Drug Delivery 10.1517/17425247.2015.1007949: 1-24 Knippenberg S, Ueberberg B, Maus R, Bohling J, Ding N, Tarres MT, Hoymann H-G, Jonigk D, Izykows ki N, Paton JC, Ogunniyi AD, Lindig S, Bauer M, Welte T, Seeger W, Guenther A, Sis s on TH, Gauldie J, Kolb M, Maus UA (2015) Streptococcus pneumoniae triggers progres s ion of pulmonary fibros is through pneumolys in. Thorax 70: 636-646 Kramer M, Quickert S, Sponholz C, Menzel U, Hus e K, Platzer M, Bauer M, Claus RA (2015) Alternative Splicing of SMPD1 in Human Seps is . PloS one 10 Kunze A, Achilles A, Keiner S, Witte OW, Redecker C (2015) Two dis tinct populations of doublecortin-pos itive cells in the periles ional zone of cortical infarcts . BMC Neuroscience 16 Lappchen CH, Ringer T, Bles s in J, Schulz K, Seidel G, Lange R, Hamzei F (2015) Daily iTBS wors ens hand motor training - A combined TMS, fMRI and mirror training s tudy. NeuroImage 107: 257-265 Leonhardt I, Spielberg S, Weber M, Albrecht-Eckardt D, Blaes s M, Claus R, Barz D, Scherlach K, Hertweck C, Loeffler J, Huenniger K, Kurzai O (2015) The Fungal Quorum-Sens ing Molecule Farnes ol Activates Innate Immune Cells but Suppres s es Cellular Adaptive Immunity. mBio 6 Liu A, Weis s S, Fang H, Claus RA, Roedel J, Dirs ch O, Dahmen U (2015) Lipopolys accharide-binding protein (LBP) blockade augments the protective effect of granulocyte colony-s timulating factor (G-CSF) in a rat s eps is model. Shock 43: 497-503 Liu X, Hinney A, Scholz M, Scherag A, Tonjes A, Stumvoll M, Stadler PF, Hebebrand J, Bottcher Y (2015) Indications for Potential Parent-of-Origin Effects within the FTO Gene. PloS one 10: e0119206 Locke AE, Kahali B, Berndt SI, et al. (2015) Genetic s tudies of body mas s index yield new ins ights for obes ity biology. Nature 518: 197-206 (contributing CSCC member: Scherag A) Matthaeus -Kraemer CT, Thomas -Rueddel DO, Schwarzkopf D, Rueddel H, Poidinger B, Reinhart K, Bloos F (2015) Barriers and s upportive conditions to improve quality of care for critically ill patients : A team approach to quality improvement. J Crit Care 10.1016/j.jcrc.2015.03.022 Mayer K, Hahn-As t C, Muckter S, Schmitz A, Kraus e S, Felder L, Bekeredjian-Ding I, Molitor E, Bros s art P, von Lilienfeld-Toal M (2015) Comparis on of antibiotic prophylaxis with cotrimoxazole/colis tin (COT/COL) vers us ciprofloxacin (CIP) in patients with acute myeloid leukemia. Supportive Care in Cancer 23: 1321-1329 Murahovs chi V, Pivovarova O, Ilkavets I, Dmitrieva RM, Docke S, Keyhani-Nejad F, Gogebakan O, Os terhoff M, Kemper M, Hornemann S, Markova M, Kloting N, Stockmann M, Weickert MO, Lamounier-Zepter V, Neuhaus P, Konradi A, Dooley S, von Loeffelholz C, Bluher M, Pfeiffer AF, Rudovich N (2015) WISP1 is a novel adipokine linked to inflammation in obes ity. Diabetes 10.2337/db14-0444 Nead KT, Li A, Wehner MR, Neupane B, Gus tafs s on S, Butterworth A, Engert JC, Davis AD, Hegele RA, Miller R, den Hoed M, Khaw KT, Kilpelainen TO, Wareham N, Edwards TL, Hallmans G, Varga TV, Kardia SL, Smith JA, Zhao W, Faul JD, Weir D, Mi J, Xi B, Quinteros SC, Cooper C, Sayer AA, James on K, Grontved A, Fornage M, Sidney S, Hanis CL, Highland HM, Haring HU, Heni M, Las ky-Su J, Weis s ST, Gerhard GS, Still C, Melka MM, Paus ova Z, Paus T, Grant SF, Hakonars on H, Price RA, Wang K, Scherag A, Hebebrand J, Hinney A, BioBank Japan A-BMIGC, Franks PW, Frayling TM, McCarthy MI, Hirs chhorn JN, Loos RJ, Ingels s on E, Gers tein HC, Yus uf S, Beyene J, Anand SS, Meyre D (2015) Contribution of common non-s ynonymous variants in PCSK1 to body mas s index variation and ris k of obes ity: a s ys tematic review and meta-analys is with evidence from up to 331 175 individuals . Human molecular genetics 10.1093/hmg/ddv097 Nus s baum C, Bannenberg S, Keul P, Graler MH, Goncalves -de-Albuquerque CF, Korhonen H, von Wnuck Lipins ki K, Heus ch G, de Cas tro Faria Neto HC, Rohwedder I, Gothert JR, Pras ad VP, Haufe G, Lange-Sperandio B, Offermanns S, Sperandio M, Levkau B (2015) Sphingos ine-1-phos phate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-s electin. Nature Communications 6: 6416 Otto GP, Grunwald B, Geis C, Kothe S, Hurtado-Oliveros J, Chung HY, Ekaney M, Bockmeyer CL, Sos s dorf M, Bus ch M, Claus RA (2015) Impact of antibiotic treatment intens ity on long-term s eps is -as s ociated kidney injury in a polymicrobial peritoneal contamination and infection model. Nephron 129: 137-142 http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 3/19 Otto GP, Hurtado-Oliveros J, Chung H-Y, Knoll K, Neumann T, Mueller HJ, Herbs leb M, Kohl M, Bus ch M, Sos s dorf M, Claus RA (2015) Plas ma Neutrophil Gelatinas e-As s ociated Lipocalin Is Primarily Related to Inflammation during Seps is : A Trans lational Approach. PloS one 10 Pers TH, Karjalainen JM, Chan Y, Wes tra HJ, Wood AR, Yang J, Lui JC, Vedantam S, Gus tafs s on S, Es ko T, Frayling T, Speliotes EK, Genetic Inves tigation of ATC, Boehnke M, Raychaudhuri S, Fehrmann RS, Hirs chhorn JN, Franke L (2015) Biological interpretation of genome-wide as s ociation s tudies us ing predicted gene functions . Nature Communications 6: 5890 Pivovarova O, von Loeffelholz C, Ilkavets I, Sticht C, Zhuk S, Murahovs chi V, Lukows ki S, Docke S, Kriebel J, de Las Heras Gala T, Malas hicheva A, Kos tareva A, Lock JF, Stockmann M, Grallert H, Gretz N, Dooley S, Pfeiffer AF, Rudovich N (2015) Modulation of ins ulin degrading enzyme activity and liver cell proliferation. Cell Cycle 10.1080/15384101.2015.1046647: 1-8 Raas ch M, Rennert K, Jahn T, Peters S, Henkel T, Huber O, Schulz I, Becker H, Lorkows ki S, Funke H, Mos ig A (2015) Microfluidically s upported biochip des ign for culture of endothelial cell layers with improved perfus ion conditions . Biofabrication 7 Rautanen A, Mills TC, Gordon AC, Hutton P, Steffens M, Nuamah R, Chiche JD, Parks T, Chapman SJ, Davenport EE, Elliott KS, Bion J, Lichtner P, Meitinger T, Wienker TF, Caulfield MJ, Mein C, Bloos F, Bobek I, Cotogni P, Sramek V, Sarapuu S, Kobilay M, Ranieri VM, Rello J, Sirgo G, Weis s YG, Rus s wurm S, Schneider EM, Reinhart K, Holloway PA, Knight JC, Garrard CS, Rus s ell JA, Walley KR, Stuber F, Hill AV, Hinds CJ, Inves tigators EEG (2015) Genome-wide as s ociation s tudy of s urvival from s eps is due to pneumonia: an obs ervational cohort s tudy. The Lancet Respiratory Medicine 3: 53-60 Reis H, Putter C, Megger DA, Bracht T, Weber F, Hoffmann AC, Bertram S, Wohls chlager J, Hagemann S, Eis enacher M, Scherag A, Schlaak JF, Canbay A, Meyer HE, Sitek B, Baba HA (2015) A s tructured proteomic approach identifies 14-3-3Sigma as a novel and reliable protein biomarker in panel bas ed differential diagnos tics of liver tumors . Biochimica et Biophysica Acta 10.1016/j.bbapap.2014.10.024 Schoeneweck F, Kuhnt E, Scholz M, Brunkhors t FM, Scherag A (2015) Common genomic variation in the FER gene: us eful to s tratify patients with s eps is due to pneumonia? Intensive Care Med 41: 1379-1381 Schroder UC, Beleites C, As s mann C, Glas er U, Hubner U, Pfis ter W, Fritzs che W, Popp J, Neugebauer U (2015) Detection of vancomycin res is tances in enterococci within 3 (1/2) hours . Scientific Reports 5: 8217 Schwarzkopf D, Wes termann I, Skupin H, Riedemann NC, Reinhart K, Pfeifer R, Fritzenwanger M, Guenther A, Witte OW, Hartog CS (2015) A novel ques tionnaire to meas ure s taff perception of end-of-life decis ion making in the intens ive care unit-Development and ps ychometric tes ting. J Crit Care 30: 187-195 Seidel RA, Kahnes M, Bauer M, Pohnert G (2015) Simultaneous determination of the bilirubin oxidation end products Z-BOX A and Z-BOX B in human s erum us ing liquid chromatography coupled to tandem mas s s pectrometry. Journal of Chromatography B 974: 83-89 Shungin D, Winkler TW, Croteau-Chonka DC, et al. (2015) New genetic loci link adipos e and ins ulin biology to body fat dis tribution. Nature 518: 187-196 (contributing CSCC member: Scherag A) Silge A, Abdou E, Schneider K, Meis el S, Bocklitz T, Lu-Walther H-W, Heintzmann R, Roes ch P, Popp J (2015) Shedding light on hos t niches : label-free in s itu detection of Mycobacterium gordonae via carotenoids in macrophages by Raman micros pectros copy. Cellular microbiology 17: 832-842 Stein C, Makarewicz O, Bohnert JA, Pfeifer Y, Kes s elmeier M, Hagel S, Pletz MW (2015) Three Dimens ional Checkerboard Synergy Analys is of Colis tin, Meropenem, Tigecycline agains t Multidrug-Res is tant Clinical Klebs iella pneumonia Is olates . PloS one 10 Szafrans ki K, Kramer M (2015) It's a bit over, is that ok? The s ubtle s urplus from tandem alternative s plicing. RNA Biology 12: 115-122 Thiele M, Rabe S, Hes s enkemper W, Roell D, Barts ch S, Kraft F, Abraham TE, Houts muller AB, van Royen ME, Giannis A, Baniahmad A (2015) Novel Nor-Homo- and Spiro-Oxetan- Steroids Target the Human Androgen Receptor and Act as Antiandrogens . Current Medicinal Chemistry 22: 1156-1167 Thomas -Rueddel DO, Poidinger B, Weis s M, Bach F, Dey K, Haberle H, Kais ers U, Ruddel H, Schadler D, Scheer C, Schreiber T, Schurholz T, Simon P, Sommerer A, Schwarzkopf D, Weyland A, Wobker G, Reinhart K, Bloos F, for the Medical Education for Seps is Source C, Antibiotics s tudy g (2015) Hyperlactatemia is an independent predictor of mortality and denotes dis tinct s ubtypes of s evere s eps is and s eptic s hock. J Crit Care 10.1016/j.jcrc.2014.10.027 Ullrich N, Heinemann A, Nilews ki E, Scheffrahn I, Klode J, Scherag A, Schadendorf D, Singer BB, Helfrich I (2015) CEACAM1-3S Drives Melanoma Cells into NK Cell-Mediated Cytolys is and Enhances Patient Survival. Canc Res 75: 1897-1907 Urbach A, Brueckner J, Witte OW (2015) Cortical s preading depolarization s timulates gliogenes is in the rat entorhinal cortex. J Cereb Blood Flow Metab 35: 576-582 http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 4/19 Vettorazzi S, Bode C, Dejager L, Frappart L, Sheles t E, Klas s en C, Tas dogan A, Reichardt HM, Libert C, Schneider M, Weih F, Henriette Uhlenhaut N, David JP, Graler M, Kleiman A, Tuckermann JP (2015) Glucocorticoids limit acute lung inflammation in concert with inflammatory s timuli by induction of SphK1. Nature Communications 6: 7796 Vry MS, Trits chler LC, Hamzei F, Rijntjes M, Kaller CP, Hoeren M, Umarova R, Glauche V, Herms doerfer J, Goldenberg G, Hennig J, Weiller C (2015) The ventral fiber pathway for pantomime of object us e. NeuroImage 106: 252-263 Weis S, Bielow T, Sommerer I, Iovanna J, Malicet C, Moes s ner J, Hoffmeis ter A (2015) P8 deficiency increas es cellular ROS and induces HO-1. Arch Biochem Biophys 565: 89-94 Weis S, Franke A, Berg T, Moes s ner J, Fleig WE, Schoppmeyer K (2015) Percutaneous ethanol injection or percutaneous acetic acid injection for early hepatocellular carcinoma. Cochrane Database of Systematic Reviews 10.1002/14651858.CD006745.pub3 Wintermann GB, Brunkhors t FM, Petrows ki K, Straus s B, Oehmichen F, Pohl M, Ros endahl J (2015) Stres s Dis orders Following Prolonged Critical Illnes s in Survivors of Severe Seps is . Crit Care Med 10.1097/CCM.0000000000000936 2014 Augs ten M, Bottcher A, Spanbroek R, Rubio I, Friedrich K (2014) Graded inhibition of oncogenic Ras -s ignaling by multivalent Ras -binding domains . Cell Communication and Signaling 12: 1 Axer H, Ros endahl J, Brunkhors t FM (2014) [Neurological and ps ychological long-term effects of s eps is ]. Medizinische Klinik, Intensivmedizin und Notfallmedizin 109: 596-603 Bacher P, Kniemeyer O, Teuts chbein J, Thon M, Vodis ch M, Wartenberg D, Scharf DH, Koes ter-Eis erfunke N, Schutte M, Dubel S, As s enmacher M, Brakhage AA, Scheffold A (2014) Identification of immunogenic antigens from As pergillus fumigatus by direct multiparameter characterization of s pecific conventional and regulatory CD4+ T cells . J Immunol 193: 3332-3343 Bauer M, Kiehntopf M (2014) Shades of yellow - monitoring nutritional needs and hepatobiliary function in the critically ill. Hepatology 10.1002/hep.27076 Bayry J, Beaus s art A, Dufrene YF, Sharma M, Bans al K, Kniemeyer O, Aimanianda V, Brakhage AA, Kaveri SV, Kwon-Chung KJ, Latge JP, Beauvais A (2014) Surface s tructure characterization of As pergillus fumigatus conidia mutated in the melanin s ynthes is pathway and their human cellular immune res pons e. Infection and Immunity 82: 3141-3153 Bis kup C, Rubio I (2014) Real-time vis ualization and quantification of native Ras activation in s ingle living cells . Methods Mol Biol 1120: 285-305 Bles s in J, Hamzei F (2014) A New Approach in Neurorehabilitation – The Role of the Mirror Neuron Sys tem. Eur Neurol Rev 9: 60-63 Bloos F, Senderrek M, Bauer M (2014) Sens itivity of Blood Culture vs Polymeras e Chain Reaction for Skin Contaminants in Specimen Retrieved via the Dis tal Lumen of Seldinger-Guided Central Venous Catheters . Chest 145: 430-431 Bloos F, Thomas -Ruddel D, Ruddel H, Engel C, Schwarzkopf D, Mars hall JC, Harbarth S, Simon P, Ries s en R, Keh D, Dey K, Weis s M, Tous s aint S, Schadler D, Weyland A, Ragaller M, Schwarzkopf K, Eiche J, Kuhnle G, Hoyer H, Hartog C, Kais ers U, Reinhart K (2014) Impact of compliance with infection management guidelines on outcome in patients with s evere s eps is : a pros pective obs ervational multi-center s tudy. Crit Care 18: R42 Blume KR, Dietrich C, Huonker R, Gotz T, Sens E, Friedel R, Hofmann GO, Miltner WH, Weis s T (2014) Cortical reorganization after macroreplantation at the upper extremity: a magnetoencephalographic s tudy. Brain : a journal of neurology 137: 757-769 Bode C, Berlin M, Rös tel F, Teichmann B, Gräler MH (2014) Evaluating Sphingos ine and its Analogues as Potential Alternatives for Aggres s ive Lymphoma Treatment. Cellular Physiology and Biochemistry 34: 16861700 Bohlender C, Glas er S, Klein M, Weis s er J, Thein S, Neugebauer U, Popp J, Wyrwa R, Schiller A (2014) Lighttriggered CO releas e from nanoporous non-wovens . J Materials Chem B 2: 1454-1463 Brämer D, Hoyer D (2014) Herzfrequenzvariabilität als Marker Schlaganfall-as s oziierter Infektionen. Neurophysiol Lab 36: 23-32 Bramer D, Hoyer H, Gunther A, Nowack S, Brunkhors t FM, Witte OW, Hoyer D (2014) Study protocol: prediction of s troke as s ociated infections by markers of autonomic control. BMC neurology 14: 9 http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 5/19 Braun SD, Monecke S, Thurmer A, Ruppelt A, Makarewicz O, Pletz M, Reibetaig A, Slickers P, Ehricht R (2014) Rapid identification of carbapenemas e genes in gram-negative bacteria with an oligonucleotide microarraybas ed as s ay. PloS one 9: e102232 Brunke S, Hube B (2014) Adaptive prediction as a s trategy in microbial infections . PLoS Pathog 10: e1004356 Brunke S, Seider K, Fis cher D, Jacobs en ID, Kas per L, Jablonows ki N, Wartenberg A, Bader O, EnacheAngoulvant A, Schaller M, d'Enfert C, Hube B (2014) One Small Step for a Yeas t - Microevolution within Macrophages Renders Candida glabrata Hypervirulent Due to a Single Point Mutation. PLoS Pathog 10: e1004478 Brunke S, Seider K, Richter ME, Bremer-Streck S, Ramachandra S, Kiehntopf M, Brock M, Hube B (2014) His tidine degradation via an aminotrans feras e increas es the nutritional flexibility of Candida glabrata. Eukaryot Cell EC.00072-14 [pii] 10.1128/EC.00072-14 Brunkhors t FM (2014) Antibiotikatherapie bei Seps is --immer maximal "breit" behandeln? Drug Res 64: 9-10 Brunkhors t FM, Patchev V (2014) [Seps is -as s ociated Purpura Fulminans International Regis try-Europe (SAPFIRE).]. Medizinische Klinik, Intensivmedizin und Notfallmedizin 10.1007/s 00063-014-0402-z Bruns T, Zimmermann HW, Stallmach A (2014) Ris k factors and outcome of bacterial infections in cirrhos is . World journal of gastroenterology : WJG 20: 2542-2554 Donat CK, Fis cher F, Walter B, Deuther-Conrad W, Brodhun M, Bauer R, Brus t P (2014) Early increas e of cannabinoid receptor dens ity after experimental traumatic brain injury in the newborn piglet. Acta neurobiologiae experimentalis 74: 197-210 Donat CK, Fis cher F, Walter B, Kays er T, Deuther-Conrad W, Brodhun M, Bauer R, Brus t P (2014) Early increas e of cannbinoid receptor dens ity after experimental traumatic brain injury in the newborn piglet. Acta neurobiologiae experimentalis 74: 1-15 Dorner L, Schwarzkopf D, Skupin H, Philipp S, Gugel K, Meis s ner W, Schuler S, Hartog CS (2014) Teaching medical s tudents to talk about death and dying in the ICU: feas ibility of a peer-tutored works hop. Intensive Care Med 10.1007/s 00134-014-3541-z Ekaney M, Otto GP, Sos s dorf M, Sponholz C, Boehringer M, Loes che W, Rittirs ch D, Wilharm A, Kurzai O, Bauer M, Claus RA (2014) Impact of plas ma his tones in human s eps is and their contribution to cellular injury and inflammation. Crit Care 18: 543 Ene IV, Brunke S, Brown AJ, Hube B (2014) Metabolis m in Fungal Pathogenes is . Cold Spring Harbor perspectives in medicine 10.1101/cs hpers pect.a019695 Ewald C, Duenis ch P, Walter J, Gotz T, Witte OW, Kalff R, Gunther A (2014) Bone flap necros is after decompres s ive hemicraniectomy for malignant middle cerebral artery infarction. Neurocritical care 20: 9197 Fis cher D, Hube B, Brunke S (2014) Fine-Scale Chromos omal Changes in Fungal Fitnes s . Current Fungal Infection Reports 8: 171-178 Fris ter A, Schmidt C, Schneble N, Brodhun M, Gonnert FA, Bauer M, Hirs ch E, Muller JP, Wetzker R, Bauer R (2014) Phos phoinos itide 3-Kinas e gamma Affects LPS-Induced Dis turbance of Blood-Brain Barrier Via Lipid Kinas e-Independent Control of cAMP in Microglial Cells . Neuromolecular medicine 10.1007/s 12017-014-8320z Galler K, Brautigam K, Gros s e C, Popp J, Neugebauer U (2014) Making a big thing of a s mall cell--recent advances in s ingle cell analys is . The Analyst 139: 1237-1273 Galler K, Schles er F, Frohlich E, Requardt RP, Kortgen A, Bauer M, Popp J, Neugebauer U (2014) Exploitation of the hepatic s tellate cell Raman s ignature for their detection in native tis s ue s amples . Integrative biology : quantitative biosciences from nano to macro 6: 946-956 Geis C (2014) Effects of pooled human immunoglobulins in an animal model of neuromyelitis optica with chronic application of autoantibodies to aquaporin 4. Clinical and experimental immunology 178 Suppl 1: 130-131 Geis s ler K, Bohne S, Siggel R, Sachs e S, Kiehntopf M, Bauer M, Straube E, Guntinas -Lichius O (2014) Preoperative s erum pattern analys is to predict the outcome of tons illectomy in adults with chronic tons illitis . European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-RhinoLaryngological Societies 10.1007/s 00405-014-3084-5 Giamarellos -Bourboulis EJ (2014) Should we be moving from s uppres s ion to s timulation to deal with immunoparalys is in s eps is patients ? Immunotherapy 6: 113-115 Gondan M, Blurton SP, Kes s elmeier M (2014) Even fas ter and even more accurate firs t-pas s age time dens ities and dis tributions for the Wiener diffus ion model. J Math Psychol 60: 20-22 http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 6/19 Götz T, Günther A, Witte OW, Brunkhors t FM, Seidel G, Hamzei F (2014) Long-term s equelae of s evere s eps is : cognitive impairment and s tructural brain alterations - an MRI s tudy (Los s Cog MRI). BMC neurology 14: 145 Götz T, Huonker R, Witte OW, Haueis en J (2014) Thalamocortical Impuls e Propagation and Information Trans fer in EEG and MEG. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 31: 253-260 Griewank KG, Murali R, Puig-Butille JA, Schilling B, Livings tone E, Potrony M, Carrera C, Schimming T, Moller I, Schwamborn M, Sucker A, Hillen U, Badenas C, Malvehy J, Zimmer L, Scherag A, Puig S, Schadendorf D (2014) TERT promoter mutation s tatus as an independent prognos tic factor in cutaneous melanoma. Journal of the National Cancer Institute 106 Grimm A, Axer H (2014) Hochauflös ender Ultras chall in der Dars tellung des Plexus brachialis und der zervikalen Nervenwurzeln. Neurophysiol Lab 36: 135-146 Grimm A, Decard BF, Bis chof A, Axer H (2014) Ultras ound of the peripheral nerves in s ys temic vas culitic neuropathies . Journal of the neurological sciences 347: 44-49 Grimm A, Heiling B, Schumacher U, Witte OW, Axer H (2014) Ultras ound differentiation of axonal and demyelinating neuropathies . Muscle & nerve 50: 976-983 Grimm A, Heiling B, Witte OW, Axer H (2014) Nervenultras chall bei Polyneuropathie - s innvoll oder nicht? Neurophysiol Lab Grunewald B, Geis C (2014) Meas uring s pinal pres ynaptic inhibition in mice by dors al root potential recording in vivo. Journal of visualized experiments : JoVE 10.3791/51473 Hagel S, Bruns T, Pletz MW, Engel C, Kalff R, Ewald C (2014) External ventricular drain infections : ris k factors and outcome. Interdisciplinary perspectives on infectious diseases 2014: 708531 Hartog C, Bloos F (2014) Venous oxygen s aturation. Best practice & research Clinical anaesthesiology 28: 419-428 Hartog CS, Natans on C, Sun J, Klein HG, Reinhart K (2014) Concerns over us e of hydroxyethyl s tarch s olutions . Brit Med J 349 Hartog CS, Pes chel I, Schwarzkopf D, Curtis JR, Wes termann I, Kabis ch B, Pfeifer R, Guenther A, Michals en A, Reinhart K (2014) Are written advance directives helpful to guide end-of-life therapy in the intens ive care unit? A retros pective matched-cohort s tudy. J Crit Care 29: 128-133 Hatters ley JG, Pfeiffer AF, Roden M, Petzke KJ, Hoffmann D, Rudovich NN, Randeva HS, Vatis h M, Os terhoff M, Goegebakan O, Hornemann S, Nowotny P, Machann J, Hierholzer J, von Loeffelholz C, Mohlig M, Arafat AM, Weickert MO (2014) Modulation of amino acid metabolic s ignatures by s upplemented is oenergetic diets differing in protein and cereal fiber content. The Journal of clinical endocrinology and metabolism 10.1210/jc.2014-2302: jc20142302 Hebecker B, Naglik JR, Hube B, Jacobs en ID (2014) Pathogenicity mechanis ms and hos t res pons e during oral Candida albicans infections . Expert Rev Anti Infect Ther 10.1586/14787210.2014.916210 Henry BD, Neill DR, Becker KA, Gore S, Bricio-Moreno L, Ziobro R, Edwards MJ, Muhlemann K, Steinmann J, Kleus er B, Japtok L, Luginbuhl M, Wolfmeier H, Scherag A, Gulbins E, Kadioglu A, Draeger A, Babiychuk EB (2014) Engineered lipos omes s eques ter bacterial exotoxins and protect from s evere invas ive infections in mice. Nature biotechnology 10.1038/nbt.3037 Heyl KA, Klas s ert TE, Heinrich A, Muller MM, Klaile E, Dienemann H, Grunewald C, Bals R, Singer BB, Slevogt H (2014) Dectin-1 is expres s ed in human lung and mediates the proinflammatory immune res pons e to nontypeable Haemophilus influenzae. mBio 5: e01492-01414 Hillmann F, Linde J, Beckmann N, Cyrulies M, Stras s burger M, Heinekamp T, Haas H, Guthke R, Kniemeyer O, Brakhage AA (2014) The novel globin protein fungoglobin is involved in low oxygen adaptation of As pergillus fumigatus . Molecular microbiology 93: 539-553 Hinney A, Albayrak O, Antel J, Volckmar AL, Sims R, Chapman J, Harold D, Gerris h A, Heid IM, Winkler TW, Scherag A, Wiltfang J, Williams J, Hebebrand J, Cons ortium G, Cons ortium I, Cons ortium G (2014) Genetic variation at the CELF1 (CUGBP, elav-like family member 1 gene) locus is genome-wide as s ociated with Alzheimer's dis eas e and obes ity. American journal of medical genetics Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 10.1002/ajmg.b.32234 Hoggart CJ, Venturini G, Mangino M, Gomez F, As cari G, Zhao JH, Teumer A, Winkler TW, Ts ernikova N, Luan J, Mihailov E, Ehret GB, Zhang W, Lamparter D, Es ko T, Mace A, Rueger S, Bochud PY, Barcella M, Dauvilliers Y, Benyamin B, Evans DM, Hayward C, Lopez MF, Franke L, Rus s o A, Heid IM, Salvi E, Vendantam S, Arking DE, Boerwinkle E, Chambers JC, Fiorito G, Grallert H, Guarrera S, Homuth G, Huffman JE, Porteous D, Generation Scotland C, LifeLines Cohort s , Cons ortium G, Moradpour D, Iranzo A, Hebebrand J, Kemp JP, Lammers GJ, Aubert V, Heim MH, Martin NG, Montgomery GW, Peraita-Adrados R, Santamaria J, Negro F, Schmidt CO, Scott RA, Spector TD, Strauch K, Volzke H, Wareham NJ, Yuan W, Bell JT, Chakravarti A, Kooner JS, Peters A, Matullo http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 7/19 G, Wallas chofs ki H, Whitfield JB, Paccaud F, Vollenweider P, Bergmann S, Beckmann JS, Tafti M, Has tie ND, Cus i D, Bochud M, Frayling TM, Mets palu A, Jarvelin MR, Scherag A, Smith GD, Borecki IB, Rous s on V, Hirs chhorn JN, Rivolta C, Loos RJ, Kutalik Z (2014) Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mas s Index. PLoS genetics 10: e1004508 Hoppe S, von Loeffelholz C, Lock JF, Doecke S, Sinn BV, Rieger A, Malinows ki M, Pfeiffer AFH, Neuhaus P, Stockmann M (2014) Nonalcoholic Steatohepatits and Liver Steatos is Modify Partial Hepatectomy Recovery. Journal of investigative surgery : the official journal of the Academy of Surgical Research InanlooRahatloo K, Pars a AF, Hus e K, Ras ooli P, Davaran S, Platzer M, Kramer M, Fan JB, Turk C, Amini S, Steemers F, Gunders on K, Ronaghi M, Elahi E (2014) Mutation in ST6GALNAC5 identified in family with coronary artery dis eas e. Scientific reports 4: 3595 Jacobs en ID, Luttich A, Kurzai O, Hube B, Brock M (2014) In vivo imaging of dis s eminated murine Candida albicans infection reveals unexpected hos t s ites of fungal pers is tence during antifungal therapy. The Journal of antimicrobial chemotherapy 69: 2785-2796 Jbeily N, Claus RA, Dahlke K, Neugebauer U, Bauer M, Gonnert FA (2014) Comparative s uitability of CFDA-SE and rhodamine 6G for in vivo as s es s ment of leukocyte-endothelium interactions . J Biophotonics 7: 369-375 Joerk A, Seidel RA, Walter SG, Wiegand A, Kahnes M, Klopfleis ch M, Kirms e K, Pohnert G, Wes terhaus en M, Witte OW, Holthoff K (2014) Impact of heme and heme degradation products on vas cular diameter in mous e vis ual cortex. Journal of the American Heart Association 3 Karaca I, Tamboli IY, Glebov K, Richter J, Fell LH, Grimm MO, Haupenthal VJ, Hartmann T, Graler MH, van Echten-Deckert G, Walter J (2014) Deficiency of Sphingos ine-1-phos phate Lyas e Impairs Lys os omal Metabolis m of the Amyloid Precurs or Protein. The Journal of biological chemistry 289: 16761-16772 Karner M, Kocjan A, Stein J, Schreiber S, von Boyen G, Uebel P, Schmidt C, Kupcins kas L, Dina I, Zuelch F, Keilhauer G, Stremmel W (2014) Firs t Multicenter Study of Modified Releas e Phos phatidylcholine "LT-02" in Ulcerative Colitis : A Randomized, Placebo-Controlled Trial in Mes alazine-Refractory Cours es . The American journal of gastroenterology 10.1038/ajg.2014.104 Kas per L, Seider K, Gerwien F, Allert S, Brunke S, Schwarzmuller T, Ames L, Zubiria-Barrera C, Mans our MK, Becken U, Barz D, Vyas JM, Reiling N, Haas A, Haynes K, Kuchler K, Hube B (2014) Identification of Candida glabrata Genes Involved in pH Modulation and Modification of the Phagos omal Environment in Macrophages . PloS one 9: e96015 Kes s elmeier M, Legrand C, Peil B, Kabis ch M, Fis cher C, Hamann U, Bermejo JL (2014) Practical inves tigation of the performance of robus t logis tic regres s ion to predict the genetic ris k of hypertens ion. BMC Proceedings 8: S65 Klas s ert TE, Hanis ch A, Brauer J, Klaile E, Heyl KA, Mans our MM, Tam JM, Vyas JM, Slevogt H (2014) Modulatory role of vitamin A on the Candida albicans -induced immune res pons e in human monocytes . Med Microbiol Immunol 10.1007/s 00430-014-0351-4 Klein M, Neugebauer U, Gheis ari A, Malas s a A, Jazzazi TM, Froehlich F, Wes terhaus en M, Schmitt M, Popp J (2014) IR s pectros copic methods for the inves tigation of the CO releas e from CORMs . The journal of physical chemistry A 118: 5381-5390 Kool M, Jones DT, Jager N, Northcott PA, Pugh TJ, Hoves tadt V, Piro RM, Es parza LA, Markant SL, Remke M, Milde T, Bourdeaut F, Ryzhova M, Sturm D, Pfaff E, Stark S, Hutter S, Seker-Cin H, Johann P, Bender S, Schmidt C, Raus ch T, Shih D, Reimand J, Sieber L, Wittmann A, Linke L, Witt H, Weber UD, Zapatka M, Konig R, Beroukhim R, Bergthold G, van Sluis P, Volckmann R, Kos ter J, Vers teeg R, Schmidt S, Wolf S, Lawerenz C, Bartholomae CC, von Kalle C, Unterberg A, Herold-Mende C, Hofer S, Kulozik AE, von Deimling A, Scheurlen W, Fels berg J, Reifenberger G, Has s elblatt M, Crawford JR, Grant GA, Jabado N, Perry A, Cowdrey C, Croul S, Zadeh G, Korbel JO, Doz F, Delattre O, Bader GD, McCabe MG, Collins VP, Kieran MW, Cho YJ, Pomeroy SL, Witt O, Brors B, Taylor MD, Schuller U, Kors hunov A, Eils R, Wechs ler-Reya RJ, Lichter P, Pfis ter SM, Project IPT (2014) Genome s equencing of SHH medulloblas toma predicts genotype-related res pons e to s moothened inhibition. Cancer cell 25: 393-405 Kortgen A (2014) Surrogates of peripheral microcirculation to predict weaning failure, yet another piece of the puzzle. Minerva anestesiologica 80: 1156-1157 Kroll K, Pahtz V, Hillmann F, Vaknin Y, Schmidt-Heck W, Roth M, Jacobs en ID, Os herov N, Brakhage AA, Kniemeyer O (2014) Identification of hypoxia-inducible target genes of As pergillus fumigatus by trans criptome analys is reveals cellular res piration as an important contributor to hypoxic s urvival. Eukaryot Cell 13: 1241-1253 Krus e M, von Loeffelholz C, Hoffmann D, Pohlmann A, Seltmann AC, Os terhoff M, Hornemann S, Pivovarova O, Rohn S, Jahreis G, Pfeiffer AF (2014) Dietary rapes eed/canola oil s upplementation reduces s erum lipids and liver enzymes and alters pos tprandial inflammatory res pons es in adipos e tis s ue compared to olive oil s upplementation in obes e men. Molecular nutrition & food research 10.1002/mnfr.201400446 Kumar V, Cheng SC, Johns on MD, Smeekens SP, Wojtowicz A, Giamarellos -Bourboulis E, Karjalainen J, Franke http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 8/19 L, Withoff S, Plantinga TS, van de Veerdonk FL, van der Meer JW, Joos ten LA, Sokol H, Bauer H, Herrmann BG, Bochud PY, Marchetti O, Perfect JR, Xavier RJ, Kullberg BJ, Wijmenga C, Netea MG (2014) Immunochip SNP array identifies novel genetic variants conferring s us ceptibility to candidaemia. Nature communications 5: 4675 Kunze A, Dres cher R, Kais er K, Frees meyer M, Witte OW, Axer H (2014) Serial FDG PET/CT in autoimmune encephalitis with faciobrachial dys tonic s eizures . Clinical nuclear medicine 39: e436-438 Lapp K, Vodis ch M, Kroll K, Stras s burger M, Kniemeyer O, Heinekamp T, Brakhage AA (2014) Characterization of the As pergillus fumigatus detoxification s ys tems for reactive nitrogen intermediates and their impact on virulence. Front Microbiol 5: 469 Lias kou E, Jeffery LE, Trivedi PJ, Reynolds GM, Sures h S, Bruns T, Adams DH, Sans om DM, Hirs chfield GM (2014) Los s of CD28 Expres s ion by Liver-infiltrating T cells Contributes to Pathogenes is of Primary Scleros ing Cholangitis . Gastroenterology 10.1053/j.gas tro.2014.04.003 Licht V, Noack K, Schlott B, Fors ter M, Schlenker Y, Licht A, Kramer OH, Heinzel T (2014) Cas pas e-3 and Cas pas e-6 cleave STAT1 in leukemic cells . Oncotarget 5: 2305-2317 Lynen Jans en P, Stallmach A, Lohs e AW, Lerch MM (2014) [Development of Gas trointes tinal Infectious Dis eas es between 2000 and 2012]. Zeitschrift fur Gastroenterologie 52: 549-557 Malkewitz A, Makarewicz O, Kentouche K, Keller P, Karras ch M, Pletz MW (2014) Eps tein-Barr Virus MicroRNAs in plas ma as potential biomarkers for chronic infections : (res pons e to: Kawano et al; The Journal of Infectious Dis eas es ; 2013; 208:771-9). The Journal of infectious diseases 209: 1297-1298 Mancini M, Soldovieri MV, Ges s ner G, Wis s uwa B, Barres e V, Bos cia F, Secondo A, Miceli F, Franco C, Ambros ino P, Canzoniero LM, Bauer M, Hos hi T, Heinemann SH, Taglialatela M (2014) Critical role of largeconductance calcium- and voltage-activated potas s ium channels in leptin-induced neuroprotection of Nmethyl-d-as partate-expos ed cortical neurons . Pharmacological research : the official journal of the Italian Pharmacological Society 87: 80-86 Markwart R, Condotta SA, Requardt RP, Borken F, Schubert K, Weigel C, Bauer M, Griffith TS, Fors ter M, Brunkhors t FM, Badovinac VP, Rubio I (2014) Immunos uppres s ion after s eps is : s ys temic inflammation and s eps is induce a los s of naive T-cells but no enduring cell-autonomous defects in T-cell function. PloS one 9: e115094 Mayerl S, Muller J, Bauer R, Richert S, Kas s mann CM, Darras VM, Buder K, Boelen A, Vis s er TJ, Heuer H (2014) Trans porters MCT8 and OATP1C1 maintain murine brain thyroid hormone homeos tas is . The Journal of clinical investigation 124: 1987-1999 Mech F, Wils on D, Lehnert T, Hube B, Thilo Figge M (2014) Epithelial invas ion outcompetes hypha development during Candida albicans infection as revealed by an image-bas ed s ys tems biology approach. Cytometry Part A : the journal of the International Society for Analytical Cytology 85: 126-139 Mehlhorn J, Freytag A, Schmidt K, Brunkhors t FM, Graf J, Troitzs ch U, Schlattmann P, Wens ing M, Gens ichen J (2014) Rehabilitation Interventions for Pos tintens ive Care Syndrome: A Sys tematic Review. Crit Care Med 10.1097/CCM.0000000000000148 Miramon P, Dunker C, Kas per L, Jacobs en ID, Barz D, Kurzai O, Hube B (2014) A family of glutathione peroxidas es contributes to oxidative s tres s res is tance in Candida albicans. Medical mycology : official publication of the International Society for Human and Animal Mycology 52: 223-239 Munchberg U, Ros ch P, Bauer M, Popp J (2014) Raman s pectros copic identification of s ingle bacterial cells under antibiotic influence. Analytical and bioanalytical chemistry 406: 3041-3050 Neugebauer U, Kurz C, Bocklitz T, Berger T, Velten T, Clement JH, Krafft C, Popp J (2014) Raman-Spectros copy Bas ed Cell Identification on a Microhole Array Chip. Micromachines 5: 204-215 Neugebauer U, Trenkmann S, Bocklitz T, Schmerler D, Kiehntopf M, Popp J (2014) Fas t differentiation of SIRS and s eps is from blood plas ma of ICU patients us ing Raman s pectros copy. J Biophotonics 7: 232-240 Otto GP, Sos s dorf M, Breuel H, Schlattmann P, Bayer O, Claus RA, Riedemann NC, Bus ch M (2014) Renal outcome after vancomycin treatment and renal replacement therapy in patients with s evere s eps is and s eptic s hock: a retros pective s tudy. J Crit Care 29: 656-661 Paruk F, Kis s oon N, Hartog CS, Feldman C, Hodgs on ER, Lipman J, Guidet B, Du B, Argent A, Sprung CL (2014) The Durban World Congres s Ethics Round Table Conference Report: III. Withdrawing Mechanical ventilationthe approach s hould be individualized. J Crit Care 29: 902-907 Piro RM, Wies berg S, Schramm G, Rebel N, Os wald M, Eils R, Reinelt G, Konig R (2014) Network topology-bas ed detection of differential gene regulation and regulatory s witches in cell metabolis m and s ignaling. BMC systems biology 8: 56 Pletz MW, Terkamp C, Schumacher U, Rohde G, Schütte H, Welte T, Bals R (2014) Vitamin D deficiency in http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 9/19 community-acquired pneumonia: low levels of 1,25(OH)2 D are as s ociated with dis eas e s everity. Respiratory research 15: 53 Prell T, Schenk A, Witte OW, Gros s kreutz J, Gunther A (2014) Trans cranial brains tem s onography as a diagnos tic tool for amyotrophic lateral s cleros is . Amyotrophic lateral sclerosis & frontotemporal degeneration 15: 244-249 Pres s AT, Traeger A, Piets ch C, Mos ig A, Wagner M, Clemens MG, Jbeily N, Koch N, Gotts chaldt M, Beziere N, Ermolayev V, Ntziachris tos V, Popp J, Kes s els MM, Qualmann B, Schubert US, Bauer M (2014) Cell types pecific delivery of s hort interfering RNAs by dye-functionalis ed theranos tic nanoparticles . Nature communications 5: 5565 Quintin J, Voigt J, Voort RV, Jacobs en ID, Vers chueren I, Hube B, Giamarellos -Bourboulis EJ, Meer JW, Joos ten LA, Kurzai O, Netea MG (2014) Differential role of NK cells agains t Candida albicans infection in immunocompetent or immunocompromis ed mice. European journal of immunology 10.1002/eji.201343828 Ramachandra S, Linde J, Brock M, Guthke R, Hube B, Brunke S (2014) Regulatory networks controlling nitrogen s ens ing and uptake in Candida albicans. PloS one 9: e92734 Reuken PA, Kus s mann A, Kiehntopf M, Budde U, Stallmach A, Claus RA, Bruns T (2014) Imbalance of von Willebrand factor and its cleaving proteas e ADAMTS13 during s ys temic inflammation s uperimpos ed on advanced cirrhos is . Liver Int 10.1111/liv.12657 Ros endahl J, Axer H (2014) Langzeitfolgen der Seps is – Pos ttraumatis che Belas tungs s törung, kognitive Dys funktion, neuromus kuläre Schwäche [Long term-effects of s eps is – Pos t traumatic s tres s dis order, cognitive dys function, neuromus cular weaknes s ]. Klinikarzt 43: 314-319 Schacht T, Os wald M, Eils R, Eichmuller SB, Konig R (2014) Es timating the activity of trans cription factors by the effect on their target genes . Bioinformatics 30: i401-407 Schafer ST, Ges s ner S, Scherag A, Rump K, Frey UH, Siffert W, Wes tendorf AM, Steinmann J, Peters J, Adamzik M (2014) Hydrocortis one fails to abolis h NF-kappaB1 protein nuclear trans location in deletion allele carriers of the NFKB1 promoter polymorphis m (-94ins /delATTG) and is as s ociated with increas ed 30-day mortality in s eptic s hock. PloS one 9: e104953 Schleenvoigt BT, Fobiwe JP, Keller PM, Hagel S, Pletz MW (2014) HIV pos t expos ure prophylaxis induced bicytopenia: a cas e report. AIDS research and therapy 11: 11 Schleenvoigt BT, Gajda M, Baier M, Groten T, Oppel-Heuchel H, Grimm MO, Pfis ter W, Richter J, Pletz MW (2014) Placental Schis tos oma haematobium infection in a German returnee from Malawi. Infection 10.1007/s 15010-014-0684-3 Schmidt B, Dragano N, Scherag A, Pechlivanis S, Hoffmann P, Nothen MM, Erbel R, Jockel KH, Moebus S (2014) Exploring genetic variants predis pos ing to diabetes mellitus and their as s ociation with indicators of s ocioeconomic s tatus . BMC public health 14: 609 Schmidt K, Thiel P, Mueller F, Schmuecker K, Worrack S, Mehlhorn J, Engel C, Brenk-Franz K, Kaus che S, Jakobi U, Bindara-Klippel A, Schneider N, Freytag A, Davydow D, Wens ing M, Brunkhors t FM, Gens ichen J (2014) Seps is s urvivors monitoring and coordination in outpatient health care (SMOOTH): s tudy protocol for a randomized controlled trial. Trials 15: 283 Schulz A, Walther C, Morris on H, Bauer R (2014) In vivo electrophys iological meas urements on mous e s ciatic nerves . Journal of visualized experiments : JoVE 10.3791/51181 Schwarzmuller T, Ma B, Hiller E, Is tel F, Ts cherner M, Brunke S, Ames L, Firon A, Green B, Cabral V, MarcetHouben M, Jacobs en ID, Quintin J, Seider K, Frohner I, Glas er W, Jungwirth H, Bachellier-Bas s i S, Chauvel M, Zeidler U, Ferrandon D, Gabaldon T, Hube B, d'Enfert C, Rupp S, Cormack B, Haynes K, Kuchler K (2014) Sys tematic phenotyping of a large-s cale Candida glabrata deletion collection reveals novel antifungal tolerance genes . PLoS Pathog 10: e1004211 Seidel RA, Schowtka B, Klopfleis ch M, Küh T, Weiland A, Koch A, Görls H, Imhof D, Pohnert G, Wes terhaus en M (2014) Total s ynthes is and characterization of the bilirubin oxidation product (Z)-2-(4-ethenyl-3-methyl-5oxo-1,5-dihydro-2H-pyrrol-2-ylidene)ethanamide (Z-BOX B). Tetrahedron Letters 55: 6526-6529 Seider K, Gerwien F, Kas per L, Allert S, Brunke S, Jablonows ki N, Schwarzmuller T, Barz D, Rupp S, Kuchler K, Hube B (2014) Immune evas ion, s tres s res is tance, and efficient nutrient acquis ition are crucial for intracellular s urvival of Candida glabrata within macrophages . Eukaryot Cell 13: 170-183 Sponholz C, Bayer O, Kabis ch B, Wurm K, Ebert K, Bauer M, Kortgen A (2014) Anticoagulation s trategies in venovenous hemodialys is in critically ill patients : a five-year evaluation in a s urgical intens ive care unit. TheScientificWorldJournal 2014: 808320 Sponholz C, Gonnert FA, Kortgen A, Bauer M (2014) [Monitoring of liver function in the critically ill]. Anaesthesist 63: 603-612; quiz 613-604 http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 10/19 Sponholz C, Schelenz C, Reinhart K, Schirmer U, Stehr SN (2014) Catecholamine and volume therapy for cardiac s urgery in Germany--res ults from a pos tal s urvey. PloS one 9: e103996 Sponholz C, Settmacher U, Bauer M, Kortgen A (2014) Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy in the Perioperative Care of Liver Trans plant Recipients : A Single Center Experience. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 10.1111/1744-9987.12196 Sprung CL, Paruk F, Kis s oon N, Hartog CS, Lipman J, Du B, Argent A, Hodgs on RE, Guidet B, Groeneveld AB, Feldman C (2014) The Durban World Congres s Ethics Round Table Conference Report: I. Differences between withholding and withdrawing life-s us taining treatments . J Crit Care 29: 890-895 Sprung CL, Truog RD, Curtis JR, Joynt GM, Baras M, Michals en A, Briegel J, Kes ecioglu J, Efferen L, De Robertis E, Bulpa P, Metnitz P, Patil N, Hawryluck L, Manthous C, Moreno R, Leonard S, Hill NS, Wennberg E, McDermid RC, Miks tacki A, Mulars ki RA, Hartog CS, Avidan A (2014) Seeking Worldwide Profes s ional Cons ens us on the Principles of End-of-Life Care for the Critically Ill. The Cons ens us for Worldwide End-of-Life Practice for Patients in Intens ive Care Units (WELPICUS) Study. American journal of respiratory and critical care medicine 190: 855-866 Stewards on AJ, Harbarth S, Graves N, Group TS (2014) Valuation of hos pital bed-days releas ed by infection control programs : a comparis on of methods . Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 35: 1294-1297 Stubendorff B, Finke S, Walter M, Kniemeyer O, von Eggeling F, Grus chwitz T, Steiner T, Ott U, Wolf G, Wunderlich H, Junker K (2014) Urine protein profiling identified alpha-1-microglobulin and haptoglobin as biomarkers for early diagnos is of acute allograft rejection following kidney trans plantation. World journal of urology 32: 1619-1624 Suratanee A, Schaefer MH, Betts MJ, Soons Z, Manns perger H, Harder N, Os wald M, Gipp M, Ramminger E, Marcus G, Manner R, Rohr K, Wanker E, Rus s ell RB, Andrade-Navarro MA, Eils R, Konig R (2014) Characterizing protein interactions employing a genome-wide s iRNA cellular phenotyping s creen. PLoS computational biology 10: e1003814 Thuy AV, Reimann CM, Hemdan NY, Graler MH (2014) Sphingos ine 1-phos phate in blood: function, metabolis m, and fate. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 34: 158-171 Trivedi PJ, Bruns T, Cheung A, Li KK, Kittler C, Kumagi T, Shah H, Corbett C, Al-Harthy N, Acars u U, Coltes cu C, Tripathi D, Stallmach A, Neuberger J, Jans s en HL, Hirs chfield GM (2014) Optimis ing ris k s tratification in primary biliary cirrhos is : AST/platelet ratio index predicts outcome independent of urs odeoxycholic acid res pons e. J Hepatol 10.1016/j.jhep.2014.01.029 Ummanni R, Manns perger HA, Sonntag J, Os wald M, Sharma AK, Konig R, Korf U (2014) Evaluation of revers e phas e protein array (RPPA)-bas ed pathway-activation profiling in 84 non-s mall cell lung cancer (NSCLC) cell lines as platform for cancer proteomics and biomarker dis covery. Biochimica et biophysica acta 1844: 950959 Voigt J, Hunniger K, Bouzani M, Jacobs en ID, Barz D, Hube B, Loffler J, Kurzai O (2014) Human natural killer cells acting as phagocytes agains t Candida albicans and mounting an inflammatory res pons e that modulates neutrophil antifungal activity. The Journal of infectious diseases 209: 616-626 von Loeffelholz C (2014) The Role of Non-exercis e Activity Thermogenes is in Human Obes ity. In Endotext, De Groot LJ, Beck-Peccoz P, Chrous os G, Dungan K, Gros s man A, Hers hman JM, Koch C, McLachlan R, New M, Rebar R, Singer F, Vinik A, Weickert MO (eds ). South Dartmouth (MA) Ward A, Shukla K, Balwierz A, Soons Z, Konig R, Sahin O, Wiemann S (2014) MicroRNA-519a is a novel oncomir conferring tamoxifen res is tance by targeting a network of tumour-s uppres s or genes in ER+ breas t cancer. The Journal of pathology 10.1002/path.4363 Wartenberg A, Linde J, Martin R, Schreiner M, Horn F, Jacobs en ID, Jenull S, Wolf T, Kuchler K, Guthke R, Kurzai O, Forche A, d'Enfert C, Brunke S, Hube B (2014) Microevolution of Candida albicans in Macrophages Res tores Filamentation in a Nonfilamentous Mutant. PLoS genetics 10: e1004824 Weber M, Hagel S, Stallmach A (2014) Gas trointes tinale Infektionen [Gas trointes tinal infections ]. Dtsch Med Wochenschr 25/26: 1357-1372 Werner C, Has elmann H, Weis haupt A, Toyka KV, Sommer C, Geis C (2014) Stiff pers on-s yndrome IgG affects pres ynaptic GABAergic releas e mechanis ms . Journal of neural transmission 10.1007/s 00702-014-1268-1 Wils on D, Mayer FL, Miramon P, Sles iona S, Jacobs en ID, Hube B (2014) Candida albicans s pecific genes : dis tinct roles in hos t-pathogen interactions . Eukaryot Cell 13: 977-989 Winkler TW, Day FR, Croteau-Chonka DC, Wood AR, Locke AE, Magi R, Ferreira T, Fall T, Graff M, Jus tice AE, Luan J, Gus tafs s on S, Randall JC, Vedantam S, Workalemahu T, Kilpelainen TO, Scherag A, Es ko T, Kutalik Z, Heid IM, Loos RJ, Genetic Inves tigation of Anthropometric Traits C (2014) Quality control and conduct of http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 11/19 genome-wide as s ociation meta-analys es . Nature protocols 9: 1192-1212 Wood AR, Es ko T, Yang J, et al. (2014) Defining the role of common variation in the genomic and biological architecture of adult human height. Nature genetics 46: 1173-1186 (contributing CSCC member: Scherag A) Ziels ke J, Bohne S, Axer H, Brunkhors t FM, Guntinas -Lichius O (2014) [Dys phagia management of acute and long-term critically ill intens ive care patients ]. Medizinische Klinik, Intensivmedizin und Notfallmedizin 109: 516-525 Ziels ke J, Bohne S, Brunkhors t FM, Axer H, Guntinas -Lichius O (2014) Acute and long-term dys phagia in critically ill patients with s evere s eps is : res ults of a pros pective controlled obs ervational s tudy. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies 271: 3085-3093 2013 As choff M, Hotz-Wagenblatt A, Glatting KH, Fis cher M, Eils R, Konig R (2013) SplicingCompas s : differential s plicing detection us ing RNA-Seq data. Bioinformatics 10.1093/bioinformatics /btt101 Axer H, Grimm A, Porzelius C, Tes chner U, Schumacher U, Witte OW, Brunkhors t FM (2013) Impairment of s mall s omatic and autonomic nerve fibres in intens ive care unit patients with s evere s eps is and critical illnes s polyneuropathy -- a s ingle center controlled obs ervational s tudy. BMC neurology 13: 159 Axer H, Zinke J, Axer M, Grimm A (2013) Elektrophys iologis che Diagnos tik der Critical Illnes s Polyneuropathie und Critical Illnes s Myopathie. Neurophysiol Lab 35: 18-33 Bacher P, Kniemeyer O, Schonbrunn A, Sawitzki B, As s enmacher M, Riets chel E, Steinbach A, Cornely OA, Brakhage AA, Thiel A, Scheffold A (2013) Antigen-s pecific expans ion of human regulatory T cells as a major tolerance mechanis m agains t mucos al fungi. Mucosal immunology 10.1038/mi.2013.107 Bacher P, Schink C, Teuts chbein J, Kniemeyer O, As s enmacher M, Brakhage AA, Scheffold A (2013) AntigenReactive T Cell Enrichment for Direct, High-Res olution Analys is of the Human Naive and Memory Th Cell Repertoire. J Immunol 10.4049/jimmunol.1202221 Bayer O, Schwarzkopf D, Doens t T, Cook D, Kabis ch B, Schelenz C, Bauer M, Riedemann NC, Sakr Y, Kohl M, Reinhart K, Hartog CS (2013) Perioperative fluid therapy with tetras tarch and gelatin in cardiac s urgery-a pros pective s equential analys is *. Crit Care Med 41: 2532-2542 Beauvais A, Bozza S, Kniemeyer O, Formos a C, Balloy V, Henry C, Robers on RW, Dague E, Chignard M, Brakhage AA, Romani L, Latge JP (2013) Deletion of the alpha-(1,3)-Glucan Synthas e Genes Induces a Res tructuring of the Conidial Cell Wall Res pons ible for the Avirulence of As pergillus fumigatus . PLoS Pathog 9: e1003716 Beleites C, Neugebauer U, Bocklitz T, Krafft C, Popp J (2013) Sample s ize planning for clas s ification models . Analytica chimica acta 760: 25-33 Bielecki P, Komor U, Bielecka A, Mus ken M, Puchalka J, Pletz MW, Ballmann M, Martins Dos Santos VA, Weis s S, Haus s ler S (2013) Ex vivo trans criptional profiling reveals a common s et of genes important for the adaptation of Ps eudomonas aeruginos a to chronically infected hos t s ites . Environmental microbiology 15: 570-587 Bloos F, Bayer O, Sachs e S, Straube E, Reinhart K, Kortgen A (2013) Attributable cos ts of patients with candidemia and potential implications of polymeras e chain reaction-bas ed pathogen detection on antifungal therapy in patients with s eps is . J Crit Care 28: 2-8 Bohne S, Siggel R, Sachs e S, Kiehntopf M, Bauer M, Straube E, Guntinas -Lichius O (2013) Clinical s ignificance and diagnos tic us efulnes s of s erologic markers for improvement of outcome of tons illectomy in adults with chronic tons illitis . Journal of negative results in biomedicine 12: 11 Brunke S, Hube B (2013) Two unlike cous ins : Candida albicans and C. glabrata infection s trategies . Cellular microbiology 10.1111/cmi.12091 Caldarelli A, Muller JP, Pas kows ki-Rogacz M, Herrmann K, Bauer R, Koch S, Heninger AK, Kras tev D, Ding L, Kas per S, Fis cher T, Brodhun M, Bohmer FD, Buchholz F (2013) A genome-wide RNAi s creen identifies proteins modulating aberrant FLT3-ITD s ignaling. Leukemia 10.1038/leu.2013.83 Chris taki E, Giamarellos -Bourboulis EJ (2013) The complex pathogenes is of bacteremia: From antimicrobial clearance mechanis ms to the genetic background of the hos t. Virulence 5 Docke S, Lock JF, Birkenfeld AL, Hoppe S, Lies ke S, Rieger A, Ras chzok N, Sauer IM, Florian S, Os terhoff MA, Heller R, Herrmann K, Lindenmuller S, Horn P, Bauer M, Weickert MO, Neuhaus P, Stockmann M, Mohlig M, Pfeiffer AF, von Loeffelholz C (2013) Elevated hepatic chemerin mRNA expres s ion in human non-alcoholic fatty liver dis eas e. European journal of endocrinology / European Federation of Endocrine Societies 169: 547http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 12/19 557 Dorr JR, Yu Y, Milanovic M, Beus ter G, Zas ada C, Dabritz JH, Lis ec J, Lenze D, Gerhardt A, Schleicher K, Kratzat S, Purfurs t B, Walenta S, Mueller-Klies er W, Graler M, Hummel M, Keller U, Buck AK, Dorken B, Willmitzer L, Reimann M, Kempa S, Lee S, Schmitt CA (2013) Synthetic lethal metabolic targeting of cellular s enes cence in cancer therapy. Nature 10.1038/nature12437 Fang H, Liu A, Sun J, Kitz A, Dirs ch O, Dahmen U (2013) Granulocyte Colony Stimulating Factor Induces Lipopolys accharide (LPS) Sens itization via Upregulation of LPS Binding Protein in Rat. PloS one 8: e56654 Finkens ieper A, Bekhite MM, Fis cher H, Nitza S, al. e (2013) Antibacterial Capacity of Differentiated Murine Embryonic Stem Cells During Defined in vitro Inflammatory Conditions . StemCellDev Geis s ler KJ, Jung MJ, Riecken LB, Sperka T, Cui Y, Schacke S, Merkel U, Markwart R, Rubio I, Than ME, Breithaupt C, Peuker S, Seifert R, Kaupp UB, Herrlich P, Morris on H (2013) Regulation of Son of s evenles s by the membrane-actin linker protein ezrin. Proceedings of the National Academy of Sciences of the United States of America 110: 20587-20592 Ghanem H, Hagel S, Keller P, Prochnau D, Stallmach A, Pletz MW (2013) [A 22-year-old patient from Ghana with fever and reduced CD4 T-cell count]. Internist (Berl) 54: 100-104 Giamarellos -Bourboulis EJ (2013) The failure of biologics in s eps is : where do we s tand? International journal of antimicrobial agents 42 Suppl: S45-47 Giannits ioti E, Damoraki G, Rokkas C, Ts aganos T, Fragou A, Kannelaki S, Athanas ia S, Giamarellos Bourboulis EJ (2013) Impact of haplotypes of TNF in the natural cours e of infective endocarditis . Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20: 459-464 Giatrakos S, Hus e K, Kanni T, Tzanetakou V, Kramer M, Grech I, Papadavid E, Katoulis A, Stavrianeas N, Nothnagel M, Platzer M, Bauer M, Giamarellos -Bourboulis EJ (2013) Haplotypes of IL-12Rbeta1 impact on the clinical phenotype of hidradenitis s uppurativa. Cytokine 10.1016/j.cyto.2013.03.008 Gonnert FA, Recknagel P, Hilger I, Claus RA, Bauer M, Kortgen A (2013) Hepatic excretory function in s eps is : implications from biophotonic analys is of trans cellular xenobiotic trans port in a rodent model. Crit Care 17: R67 Götz T, Huonker R, Kranczioch C, Reuken P, Witte OW, Günther A, Debener S (2013) Impaired evoked and res ting-s tate brain os cillations in patients with liver cirrhos is as revealed by magnetoencephalography. NeuroImage: Clinical 2: 873-882 Grimm A, Brunkhors t FM, Axer H (2013) Neuromus kuläre Schwäche-Seps is -induzierte CIP und CIM. NeuroTransmitter 24: 36-43 Grimm A, Tes chner U, Porzelius C, Ludewig K, Ziels ke J, Witte OW, Brunkhors t FM, Axer H (2013) Mus cle ultras ound for early as s es s ment of critical illnes s neuromyopathy in s evere s eps is . Crit Care 17: R227 Grimm A, Witte OW, Axer H (2013) Mus kelultras chall in der neurologis chen Diagnos tik – ein Überblick. Neurophysiol Lab 35: 47-60 Hagel S, Ludewig K, Fros ins ki J, Hutagalung R, Porzelius C, Gas tmeier P, Harbarth S, Pletz MW, Brunkhors t FM (2013) [Effectivenes s of a hos pital-wide educational programme for infection control to reduce the rate of health-care as s ociated infections and related s eps is (ALERTS) - methods and interim res ults ]. Dtsch Med Wochenschr 138: 1717-1722 Hagel S, Pletz MW, Brunkhors t FM, Seifert H, Kern WV (2013) [Bacteremia and s eps is ]. Internist (Berl) 54: 399407 Hagel S, Stallmach A, Keller P, Pletz M (2013) [Multires is tant Organis ms .]. Zentralbl Chir 10.1055/s -00321328343 Hartog CS, Jens en HI (2013) Family-centered ICU care may be good for everyone. Intensive Care Med 10.1007/s 00134-013-2996-7 Hartog CS, Welte T, Schlattmann P, Reinhart K (2013) Fluid replacement with hydroxyethyl s tarch in critical care--a reas s es s ment. Deutsches Arzteblatt international 110: 443-450 Hennicke F, Grumbt M, Lermann U, Uebers chaar N, Palige K, Bottcher B, Jacobs en ID, Staib C, Mors chhaus er J, Monod M, Hube B, Hertweck C, Staib P (2013) Factors s upporting cys teine tolerance and s ulfite production in Candida albicans . Eukaryot Cell EC.00336-12 [pii] 10.1128/EC.00336-12 Heublein S, Wehner F, Hochs mann B, Hochhaus A, Hartmann M, La Ros ee P (2013) Modelling cos t effectivenes s of hors e antithymocyte globulin for treating s evere aplas tic anaemia in Germany. Annals of hematology 10.1007/s 00277-013-1688-2 Holters S, Anacker J, Jans en L, Beer-Grondke K, Durs t M, Rubio I (2013) Tetras panin 1 promotes invas ivenes s http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 13/19 of cervical cancer cells . International journal of oncology 43: 503-512 Hos hi T, Wis s uwa B, Tian Y, Tajima N, Xu R, Bauer M, Heinemann SH, Hou S (2013) Omega-3 fatty acids lower blood pres s ure by directly activating large-conductance Ca2+-dependent K+ channels . Proceedings of the National Academy of Sciences of the United States of America 110: 4816-4821 Hoyer D, Tets chke F, Jaekel S, Nowack S, Witte OW, Schleus s ner E, Schneider U (2013) Fetal functional brain age as s es s ed from univers al developmental indices obtained from neuro-vegetative activity patterns . PloS one 8: e74431 Jbeily N, Suckert I, Gonnert FA, Acht B, Bockmeyer CL, Gros s mann SD, Blaes s MF, Lueth A, Deigner HP, Bauer M, Claus RA (2013) Hyperres pons ivenes s of mice deficient in plas ma-s ecreted s phingomyelinas e reveals its pivotal role in early phas e of hos t res pons e. Journal of lipid research 54: 410-424 Jun JE, Rubio I, Roos e JP (2013) Regulation of Ras Exchange Factors and Cellular Localization of Ras Activation by Lipid Mes s engers in T Cells . Frontiers in immunology 4: 239 Klaile E, Klas s ert TE, Scheffrahn I, Muller MM, Heinrich A, Heyl KA, Dienemann H, Grunewald C, Bals R, Singer BB, Slevogt H (2013) Carcinoembryonic antigen (CEA)-related cell adhes ion molecules are co-expres s ed in the human lung and their expres s ion can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis , TLR3, and type I and II interferons . Respiratory research 14: 85 Klopfleis ch M, Seidel RA, Gorls H, Richter H, Beckert R, Imhof W, Reiher M, Pohnert G, Wes terhaus en M (2013) Total Synthes is and Detection of the Bilirubin Oxidation Product (Z)-2-(3-Ethenyl-4-methyl-5-oxo-1,5dihydro-2H-pyrrol-2-ylidene)ethanamide (Z-BOX A). Organic letters 15: 4608-4611 Kothe S, Muller JP, Bohmer SA, Ts chongov T, Fricke M, Koch S, Thiede C, Requardt RP, Rubio I, Bohmer FD (2013) Features of Ras activation by a mis localized oncogenic tyros ine kinas e: FLT3 ITD s ignals through KRas at the plas ma membrane of acute myeloid leukemia cells . Journal of cell science 126: 4746-4755 Kramer M, Sponholz C, Slaba M, Wis s uwa B, Claus RA, Menzel U, Hus e K, Platzer M, Bauer M (2013) Alternative 5' untrans lated regions are involved in expres s ion regulation of human heme oxygenas e-1. PloS one 8: e77224 Kretz A, Herrmann KH, Fis cher S, Engelmann C, Witte OW, Reichenbach JR, Weih F, Haenold R (2013) Dys functional NF-kappaB and brain myelin formation. European journal of human genetics : EJHG 10.1038/ejhg.2013.240 Kroll K, Pahtz V, Kniemeyer O (2013) Elucidating the fungal s tres s res pons e by proteomics . Journal of proteomics 10.1016/j.jprot.2013.06.001 Kuhl T, Wis s brock A, Goradia N, Sahoo N, Galler K, Neugebauer U, Popp J, Heinemann SH, Ohlens chlager O, Imhof D (2013) Analys is of Fe(III) Heme Binding to Cys teine-Containing Heme-Regulatory Motifs in Proteins . ACS chemical biology 10.1021/cb400317x Lindig S, Quickert S, Vodovotz Y, Wanner GA, Bauer M (2013) Age-independent co-expres s ion of antimicrobial gene clus ters in the blood of s eptic patients . International journal of antimicrobial agents 42 Suppl: S2-7 Louis K, Netea MG, Carrer DP, Kots aki A, Mylona V, Pis tiki A, Savva A, Roditis K, Alexis A, Van der Meer JW, Giamarellos -Bourboulis EJ (2013) Bacterial trans location in an experimental model of multiple organ dys functions . The Journal of surgical research 10.1016/j.js s .2013.01.064 Lubkemeier I, Requardt RP, Lin X, Sas s e P, Andrie R, Schrickel JW, Chkourko H, Bukaus kas FF, Kim JS, Frank M, Malan D, Zhang J, Wirth A, Dobrowols ki R, Mohler PJ, Offermanns S, Fleis chmann BK, Delmar M, Willecke K (2013) Deletion of the las t five C-terminal amino acid res idues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels . Basic research in cardiology 108: 348 Luttich A, Brunke S, Hube B, Jacobs en ID (2013) Serial pas s aging of Candida albicans in s ys temic murine infection s ugges ts that the wild type s train SC5314 is well adapted to the murine kidney. PloS one 8: e64482 Martin R, Albrecht-Eckardt D, Brunke S, Hube B, Hunniger K, Kurzai O (2013) A Core Filamentation Res pons e Network in Candida albicans Is Res tricted to Eight Genes . PloS one 8: e58613 Mayer FL, Wils on D, Hube B (2013) Candida albicans pathogenicity mechanis ms . Virulence 4: 119-128 Mayer FL, Wils on D, Hube B (2013) Hs p21 potentiates antifungal drug tolerance in Candida albicans . PloS one 8: e60417 Mihailidou I, Pelekanou A, Pis tiki A, Spyridaki A, Tzepi IM, Damoraki G, Giamarellos -Bourboulis EJ (2013) Dexamethas one Down-Regulates Expres s ion of Triggering Receptor Expres s ed on Myeloid Cells -1: Evidence for a TNFalpha-Related Effect. Frontiers in public health 1: 50 Miramon P, Kas per L, Hube B (2013) Thriving within the hos t: Candida s pp. interactions with phagocytic cells . Med Microbiol Immunol 10.1007/s 00430-013-0288-z http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 14/19 Mus zkieta L, Beauvais A, Pahtz V, Gibbons JG, Anton Leberre V, Beau R, Shibuya K, Rokas A, Francois JM, Kniemeyer O, Brakhage AA, Latge JP (2013) Inves tigation of As pergillus fumigatus biofilm formation by various "omics " approaches . Front Microbiol 4: 13 Neus chafer-Rube F, Lies ke S, Kuna M, Henkel J, Perry RJ, Erion DM, Pes ta D, Willmes DM, Brachs S, von Loeffelholz C, Tolkachov A, Schupp M, Pathe-Neus chafer-Rube A, Pfeiffer AF, Shulman GI, Pus chel GP, Birkenfeld AL (2013) The Mammalian INDY Homolog is Induced by CREB in a Rat Model of Type 2 Diabetes . Diabetes 10.2337/db13-0749 Offen N, Flemming J, Kamawal H, Ahmad R, Wolber W, Geis C, Zaehres H, Scholer HR, Ehrenreich H, Muller AM, Siren AL (2013) Effects of erythropoietin in murine-induced pluripotent cell-derived panneural progenitor cells . Molecular medicine 19: 399-408 Otto GP, Bus ch M, Sos s dorf M, Claus RA (2013) Impact of s eps is -as s ociated cytokine s torm on plas ma NGAL during acute kidney injury in a model of polymicrobial s eps is . Crit Care 17: 419 Otto GP, Kropf M, Rodel J, Los che W, Rus ter C, Claus RA, Sos s dorf M, Bus ch M (2013) Novel approach for bacteremia detection in patients with end-s tage renal failure undergoing hemodialys is . The International journal of artificial organs 10.5301/ijao.5000243: 0 Otto GP, Ludewig K, Jacobs en ID, Schaars chmidt B, Hube B, Bauer M (2013) Limitation of (1-->3)-beta-Dglucan monitoring in major elective s urgery involving cardiopulmonary bypas s . Crit Care 17: 437 Palige K, Linde J, Martin R, Bottcher B, Citiulo F, Sullivan DJ, Weber J, Staib C, Rupp S, Hube B, Mors chhaus er J, Staib P (2013) Global trans criptome s equencing identifies chlamydos pore s pecific markers in Candida albicans and Candida dubliniens is . PloS one 8: e61940 Papaioannou M, Soderholm AA, Hong W, Dai Y, Roediger J, Roell D, Thiele M, Nyronen TH, Baniahmad A (2013) Computational and functional analys is of the androgen receptor antagonis t atraric acid and its derivatives . Anti-cancer agents in medicinal chemistry Peter J, Frey O, Stallmach A, Bruns T (2013) Attenuated antigen-s pecific T cell res pons es in cirrhos is are accompanied by elevated s erum interleukin-10 levels and down-regulation of HLA-DR on monocytes . BMC gastroenterology 13: 37 Pietrella D, Pandey N, Gabrielli E, Pericolini E, Perito S, Kas per L, Bis toni F, Cas s one A, Hube B, Vecchiarelli A (2013) Secreted as partic proteas es of Candida albicans activate the NLRP3 inflammas ome. European journal of immunology 43: 679-692 Plaimas K, Wang Y, Rotimi SO, Olas ehinde G, Fatumo S, Lanzer M, Adebiyi E, Konig R (2013) Computational and experimental analys is identified 6-diazo-5-oxonorleucine as a potential agent for treating infection by Plas modium falciparum. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 10.1016/j.meegid.2013.09.019 Pletz MW (2013) [Pneumococcal vaccine]. Dtsch Med Wochenschr 138: 1734-1737 Pletz MW, Michaylov N, Schumacher U, van der Linden M, Dues berg CB, Fuehner T, Klugman KP, Welte T, Makarewicz O (2013) Antihypertens ives s uppres s the emergence of fluoroquinolone-res is tant mutants in pneumococci: An in vitro s tudy. International journal of medical microbiology : IJMM 10.1016/j.ijmm.2013.02.014 Prell T, Pes chel T, Kohler B, Bokemeyer MH, Dengler R, Gunther A, Gros s kreutz J (2013) Structural brain abnormalities in cervical dys tonia. BMC neuroscience 14: 123 Prkno A, Wacker C, Brunkhors t FM, Schlattmann P (2013) Procalcitonin-guided therapy in intens ive care unit patients with s evere s eps is and s eptic s hock - a s ys tematic review and meta-analys is . Crit Care 17: R291 Pye DS, Rubio I, Pus ch R, Lin K, Pettitt AR, Till KJ (2013) Chemokine unres pons ivenes s of chronic lymphocytic leukemia cells res ults from impaired endos omal recycling of rap1 and is as s ociated with a dis tinctive type of immunological anergy. J Immunol 191: 1496-1504 Recknagel P, Gonnert FA, Halilbas ic E, Gajda M, Jbeily N, Lupp A, Rubio I, Claus RA, Kortgen A, Trauner M, Singer M, Bauer M (2013) Mechanis ms and functional cons equences of liver failure s ubs tantially differ between endotoxaemia and faecal peritonitis in rats . Liver Int 33: 283-293 Reuken PA, Stallmach A, Bruns T (2013) Mortality after urinary tract infections in patients with advanced cirrhos is - Relevance of acute kidney injury and comorbidities . Liver Int 33: 220-230 Ros endahl J, Brunkhors t FM, Jaenichen D, Straus s B (2013) Phys ical and mental health in patients and s pous es after intens ive care of s evere s eps is : a dyadic pers pective on long-term s equelae tes ting the Actor-Partner Interdependence Model. Crit Care Med 41: 69-75 Rudiger A, Dys on A, Fels mann K, Carre JE, Taylor V, Hughes S, Clatworthy I, Protti A, Pellerin D, Lemm J, Claus RA, Bauer M, Singer M (2013) Early functional and trans criptomic changes in the myocardium predict outcome in a long-term rat model of s eps is . Clin Sci (Lond) 124: 391-401 http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 15/19 Rupprecht S, Walther B, Gudziol H, Steenbeck J, Frees meyer M, Witte OW, Gunther A, Schwab M (2013) Clinical markers of early nigros triatal neurodegeneration in idiopathic rapid eye movement s leep behavior dis order. Sleep medicine 14: 1064-1070 Schack M, Sachs e S, Rodel J, Frangoulidis D, Pletz MW, Rohde GU, Straube E, Boden K (2013) Coxiella burnetii (Q fever) as a caus e of community-acquired pneumonia during the warm s eas on in Germany. Epidemiology and infection 10.1017/S0950268813002914: 1-6 Schleenvoigt BT, Keller PM, Lehmann M, Gras F, Hagel S, Stallmach A, Pletz MW (2013) [Cutaneous manifes tation of tuberculos is caus ing impaired healing after minor injury]. Dtsch Med Wochenschr 138: 2297-2302 Schmidt C, Lautens chlager C, Petzold B, Sakr Y, Marx G, Stallmach A (2013) Confocal las er endomicros copy reliably detects s eps is -related and treatment-as s ociated changes in intes tinal mucos al microcirculation. British journal of anaesthesia 10.1093/bja/aet219 Schmidt C, Schneble N, Muller JP, Bauer R, Perino A, Marone R, Rybalkin SD, Wymann MP, Hirs ch E, Wetzker R (2013) Phos phoinos itide 3-kinas e gamma mediates microglial phagocytos is via lipid kinas e-independent control of cAMP. Neuroscience 233: 44-53 Schmitz RP, Keller PM, Baier M, Hagel S, Pletz MW, Brunkhors t FM (2013) Quality of blood culture tes ting - a s urvey in intens ive care units and microbiological laboratories acros s four European countries . Crit Care 17: R248 Schroder UC, Ramoji A, Glas er U, Sachs e S, Leiterer C, Cs aki A, Hubner U, Fritzs che W, Pfis ter W, Bauer M, Popp J, Neugebauer U (2013) Combined Dielectrophores is -Raman Setup for the Clas s ification of Pathogens Recovered from the Urinary Tract. Analytical chemistry 10.1021/ac4021616 Schulz A, Baader SL, Niwa-Kawakita M, Jung MJ, Bauer R, Garcia C, Zoch A, Schacke S, Hagel C, Mautner VF, Hanemann CO, Dun XP, Parkins on DB, Weis J, Schroder JM, Gutmann DH, Giovannini M, Morris on H (2013) Merlin is oform 2 in neurofibromatos is type 2-as s ociated polyneuropathy. Nature neuroscience 10.1038/nn.3348 Schwarzkopf D, Behrend S, Skupin H, Wes termann I, Riedemann NC, Pfeifer R, Gunther A, Witte OW, Reinhart K, Hartog CS (2013) Family s atis faction in the intens ive care unit: a quantitative and qualitative analys is . Intensive Care Med 39: 1071-1079 Sens E, Knorr C, Preul C, Meis s ner W, Witte OW, Miltner WH, Weis s T (2013) Differences in s omatos ens ory and motor improvement during temporary functional deafferentation in s troke patients and healthy s ubjects . Behavioural brain research 252: 110-116 Shopova I, Bruns S, Thywis s en A, Kniemeyer O, Brakhage AA, Hillmann F (2013) Extrins ic extracellular DNA leads to biofilm formation and colocalizes with matrix polys accharides in the human pathogenic fungus As pergillus fumigatus . Front Microbiol 4: 141 Song SP, Hennig A, Schubert K, Markwart R, Schmidt P, Prior IA, Bohmer FD, Rubio I (2013) Ras palmitoylation is neces s ary for N-Ras activation and s ignal propagation in growth factor s ignalling. The Biochemical journal 10.1042/BJ20121799 Sos s dorf M, Fis cher J, Meyer S, Dahlke K, Wis s uwa B, Seidel C, Schrepper A, Bockmeyer CL, Lupp A, Neugebauer S, Schmerler D, Rodel J, Claus RA, Otto GP (2013) Phys ical Exercis e Induces Specific Adaptations Res ulting in Reduced Organ Injury and Mortality During Severe Polymicrobial Seps is . Crit Care Med 41: 246255 Sos s dorf M, Otto GP, Boettel J, Winning J, Los che W (2013) Benefit of low-dos e as pirin and non-s teroidal antiinflammatory drugs in s eptic patients . Crit Care 17: 402 Sos s dorf M, Otto GP, Menge K, Claus RA, Los che W, Kabis ch B, Kohl M, Smolens ki UC, Schlattmann P, Reinhart K, Winning J (2013) Potential effect of phys iotherapeutic treatment on mortality rate in patients with s evere s eps is and s eptic s hock: A retros pective cohort analys is . J Crit Care 10.1016/j.jcrc.2013.06.023 Stallmach A, Hagel S, Bruns T, Pletz M, Eckmann C (2013) [Empirical antibiotic therapy in intra-abdomial infections : cas es and evidence-bas ed therapeutic recommendations ]. Zeitschrift fur Gastroenterologie 51: 1069-1081 Stehr SN, Woes t I, Hartog CS, Reinhart K (2013) [Seps is : Putting knowledge into practice]. Internist (Berl) 54: 63-74 Stein C, Makarewicz O, Pfeifer Y, Brandt C, Ramos JC, Klinger M, Pletz MW (2013) Direct RNA-bas ed detection and differentiation of CTX-M-type extended-s pectrum beta-lactamas es (ESBL). PloS one 8: e80079 Toufekoula C, Papadakis V, Ts aganos T, Routs i C, Orfanos SE, Kotanidou A, Carrer DP, Raftogiannis M, Baziaka F, Giamarellos -Bourboulis EJ (2013) Compartmentalization of lipid peroxidation in s eps is by multidrugres is tant gram-negative bacteria: experimental and clinical evidence. Crit Care 17: R6 http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 16/19 Wacker C, Prkno A, Brunkhors t FM, Schlattmann P (2013) Procalcitonin as a diagnos tic marker for s eps is : a s ys tematic review and meta-analys is . The Lancet infectious diseases 13: 426-435 Wagener J, Schneider JJ, Baxmann S, Kalbacher H, Borelli C, Nuding S, Kuchler R, Wehkamp J, Kaes er MD, Mailander-Sanchez D, Brauns dorf C, Hube B, Schild L, Fors s mann WG, Korting HC, Liepke C, Schaller M (2013) A peptide derived from the highly cons erved protein GAPDH is involved in tis s ue protection by different antifungal s trategies and epithelial immunomodulation. The Journal of investigative dermatology 133: 144153 Walter B, Eis elt M, Cumming P, Xiong G, Hinz R, Uthe S, Brus t P, Bauer R (2013) Res is tance of brain glucos e metabolis m to thiopental-induced CNS depres s ion in newborn piglets . International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 31: 157-164 Wils on D, Hebecker B, Moyes DL, Miramon P, Jablonows ki N, Wis gott S, Allert S, Naglik JR, Hube B (2013) Clotrimazole dampens vaginal inflammation and neutrophil infiltration in res pons e to Candida albicans infection. Antimicrobial agents and chemotherapy 57: 5178-5180 Zimmermann HW, Reuken PA, Koch A, Bartneck M, Adams DH, Trautwein C, Stallmach A, Tacke F, Bruns T (2013) Soluble urokinas e plas minogen activator receptor is compartmentally regulated in decompens ated cirrhos is and indicates immune activation and s hort-term mortality. Journal of internal medicine 274: 86-100 2012 Bauer R, Schubert H (2012) Therapeutis che Hypothermie – pathophys iologis che und molekularbiologis che Implikationen der Hirnprotektion. Intensiv- und Notfallbehandlung 37: 1-9 Bayer O, Reinhart K, Kohl M, Kabis ch B, Mars hall J, Sakr Y, Bauer M, Hartog C, Schwarzkopf D, Riedemann N (2012) Effects of fluid res us citation with s ynthetic colloids or crys talloids alone on s hock revers al, fluid balance, and patient outcomes in patients with s evere s eps is : a pros pective s equential analys is . Crit Care Med 40: 2543-2551 Bloos F, Sachs e S, Kortgen A, Pletz MW, Lehmann M, Straube E, Riedemann NC, Reinhart K, Bauer M (2012) Evaluation of a polymeras e chain reaction as s ay for pathogen detection in s eptic patients under routine condition: an obs ervational s tudy. PloS one 7: e46003 Bohne S, Schelhorn-Neis e P, Brunkhors t FM, Guntinas -Lichius O (2012) [Severe organic dys phagia after longterm ventilation in a patient with s eps is and multiorgan failure]. Medizinische Klinik, Intensivmedizin und Notfallmedizin 107: 564-566 Brunkhors t FM, Oppert M, Marx G, Bloos F, Ludewig K, Putens en C, Nierhaus A, Jas chins ki U, Meier-Hellmann A, Weyland A, Grundling M, Moerer O, Ries s en R, Seibel A, Ragaller M, Buchler MW, John S, Bach F, Spies C, Reill L, Fritz H, Kiehntopf M, Kuhnt E, Bogats ch H, Engel C, Loeffler M, Kollef MH, Reinhart K, Welte T (2012) Effect of empirical treatment with moxifloxacin and meropenem vs meropenem on s eps is -related organ dys function in patients with s evere s eps is : a randomized trial. JAMA : the journal of the American Medical Association 307: 2390-2399 Bruns T, Peter J, Reuken PA, Grabe DH, Schuldes SR, Brenmoehl J, Scholmerich J, Wies t R, Stallmach A (2012) NOD2 gene variants are a ris k factor for culture-pos itive s pontaneous bacterial peritonitis and monomicrobial bacteras cites in cirrhos is . Liver Int 32: 223-230 Bruns T, Reuken PA, Fis cher J, Berg T, Stallmach A (2012) Further evidence for the relevance of TLR2 gene variants in s pontaneous bacterial peritonitis . J Hepatol 56: 1207-1208; author reply 1208-1209 Citiulo F, Jacobs en ID, Miramon P, Schild L, Brunke S, Zipfel P, Brock M, Hube B, Wils on D (2012) Candida albicans s cavenges hos t zinc via Pra1 during endothelial invas ion. PLoS Pathog 8: e1002777 Godfrey R, Arora D, Bauer R, Stopp S, Muller JP, Heinrich T, Bohmer SA, Dagnell M, Schnetzke U, Scholl S, Os tman A, Bohmer FD (2012) Cell trans formation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor s uppres s or protein-tyros ine phos phatas e DEP-1/ PTPRJ. Blood 119: 4499-4511 Gonnert FA, Kunis ch E, Gajda M, Lambeck S, Weber M, Claus RA, Bauer M, Kinne RW (2012) Hepatic Fibros is in a Long-term Murine Model of Seps is . Shock 37: 399-407 Gow NA, Hube B (2012) Importance of the Candida albicans cell wall during commens alis m and infection. Current opinion in microbiology 15: 406-412 Grimm A, Günther A, Witte OW, Axer H (2012) Critical-Illnes s -Polyneuropathie und Critical-Illnes s -Myopathie. Medizinische Klinik, Intensivmedizin und Notfallmedizin 107: 649-659 Hartog CS, Winning J, Bauer M (2012) Volume replacement after trauma: an update. Swiss medical weekly 142: w13685 Jacobs en ID, Wils on D, Wachtler B, Brunke S, Naglik JR, Hube B (2012) Candida albicans dimorphis m as a http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 17/19 therapeutic target. Expert Rev Anti Infect Ther 10: 85-93 Jaenichen D, Brunkhors t FM, Straus s B, Ros endahl J (2012) [Phys ical and mental long-term s equelae following intens ive care of s evere s eps is in patients and relatives ]. Psychotherapie, Psychosomatik, medizinische Psychologie 62: 335-343 Kleiman A, Hubner S, Rodriguez Parkitna JM, Neumann A, Hofer S, Weigand MA, Bauer M, Schmid W, Schutz G, Libert C, Reichardt HM, Tuckermann JP (2012) Glucocorticoid receptor dimerization is required for s urvival in s eptic s hock via s uppres s ion of interleukin-1 in macrophages . Faseb J 26: 722-729 Kots aki A, Giamarellos -Bourboulis EJ (2012) Emerging drugs for the treatment of s eps is . Expert opinion on emerging drugs 17: 379-391 Kotzampas s i K, Giamarellos -Bourboulis EJ (2012) Probiotics for infectious dis eas es : more drugs , les s dietary s upplementation. International journal of antimicrobial agents 40: 288-296 Lambeck S, Weber M, Gonnert FA, Mrowka R, Bauer M (2012) Comparis on of s eps is -induced trans criptomic changes in a murine model to clinical blood s amples identifies common res pons e patterns . Front Microbiol 3: 284 Loes che W, Boettel J, Kabis ch B, Winning J, Claus RA, Bauer M (2012) Do as pirin and other antiplatelet drugs reduce the mortality in critically ill patients ? Thrombosis 2012: 720254 Mariappan A, Makarewicz O, Chen XH, Borris s R (2012) Two-component res pons e regulator DegU controls the expres s ion of bacilys in in plant-growth-promoting bacterium Bacillus amyloliquefaciens FZB42. Journal of molecular microbiology and biotechnology 22: 114-125 Mayer FL, Wils on D, Jacobs en ID, Miramon P, Sles iona S, Bohovych IM, Brown AJ, Hube B (2012) Small but crucial: the novel s mall heat s hock protein Hs p21 mediates s tres s adaptation and virulence in Candida albicans . PloS one 7: e38584 Miramon P, Dunker C, Windecker H, Bohovych IM, Brown AJ, Kurzai O, Hube B (2012) Cellular res pons es of Candida albicans to phagocytos is and the extracellular activities of neutrophils are critical to counteract carbohydrate s tarvation, oxidative and nitros ative s tres s . PloS one 7: e52850 Muller S, Baldin C, Groth M, Guthke R, Kniemeyer O, Brakhage AA, Valiante V (2012) Comparis on of trans criptome technologies in the pathogenic fungus As pergillus fumigatus reveals novel ins ights into the genome and MpkA dependent gene expres s ion. BMC genomics 13: 519 Neugebauer U, Gros s e C, Bauer M, Kemper B, Barros o-Pena A, Bauwens A, Glueder M, Woerdemann M, Dewenter L, Denz C, Klos s S, Ros ch P, Sabat A, Schutze K, Friedrich A, Bally GV, Popp J, Mellmann A (2012) From Infection to Detection: Imaging S. aureus - hos t interactions . Biomedizinische Technik Biomedical engineering 10.1515/bmt-2012-4284 Neugebauer U, Marz A, Henkel T, Schmitt M, Popp J (2012) Spectros copic detection and quantification of heme and heme degradation products . Analytical and bioanalytical chemistry 404: 2819-2829 Otto GP, Kropf M, Sos s dorf M, Recknagel P, Los che W, Rodel J, Claus RA, Bus ch M (2012) Screening for bacteremia in s eps is and renal failure us ing hemofilters for renal replacement therapy. Infection 10.1007/s 15010-012-0372-0 Otto GP, Neugebauer S, Claus RA, Sos s dorf M (2012) Arginine metabolis m is markedly impaired in polymicrobial infected mice. Crit Care 16: 412 Otto GP, Sos s dorf M, Boettel J, Kabis ch B, Breuel H, Winning J, Los che W (2012) Effects of low-dos e acetyls alicylic acid and atheros clerotic vas cular dis eas es on the outcome in patients with s evere s eps is or s eptic s hock. Platelets 10.3109/09537104.2012.724482 Otto GP, Wis s uwa B, Mehnert A, Marx S, Raes s ler M, Los che W, Claus RA, Sos s dorf M (2012) A method for detection and quantification of hydroxyethyl s tarch in plas ma. Crit Care 16: 426 Pletz MW, Ewig S, Lange C, Welte T, Hoffken G (2012) [Update pneumonia 2012]. Dtsch Med Wochenschr 137: 2265-2280; quiz 2281-2264 Quintin J, Saeed S, Martens JH, Giamarellos -Bourboulis EJ, Ifrim DC, Logie C, Jacobs L, Jans en T, Kullberg BJ, Wijmenga C, Joos ten LA, Xavier RJ, van der Meer JW, Stunnenberg HG, Netea MG (2012) Candida albicans infection affords protection agains t reinfection via functional reprogramming of monocytes . Cell host & microbe 12: 223-232 Ramoji A, Neugebauer U, Bocklitz T, Foers ter M, Kiehntopf M, Bauer M, Popp J (2012) Toward a s pectros copic hemogram: Raman s pectros copic differentiation of the two mos t abundant leukocytes from peripheral blood. Analytical chemistry 84: 5335-5342 Rauchfus s F, Lambeck S, Claus RA, Ullmann J, Schulz T, Weber M, Katenkamp K, Guthke R, Bauer M, Settmacher U (2012) Sus tained liver regeneration after portal vein embolization --a human molecular pilot s tudy. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 18/19 Association for the Study of the Liver 44: 681-688 Recknagel P, Claus RA, Neugebauer U, Bauer M, Gonnert FA (2012) In vivo imaging of hepatic excretory function in the rat by fluores cence micros copy. J Biophotonics 7: 571-581 Recknagel P, Gonnert FA, Wes termann M, Lambeck S, Lupp A, Rudiger A, Dys on A, Carre JE, Kortgen A, Krafft C, Popp J, Sponholz C, Fuhrmann V, Hilger I, Claus RA, Riedemann NC, Wetzker R, Singer M, Trauner M, Bauer M (2012) Liver dys function and phos phatidylinos itol-3-kinas e s ignalling in early s eps is : experimental s tudies in rodent models of peritonitis . PLoS medicine 9: e1001338 Reinhart K, Bauer M, Riedemann NC, Hartog CS (2012) New approaches to s eps is : molecular diagnos tics and biomarkers . Clinical microbiology reviews 25: 609-634 Requardt RP, Hirrlinger PG, Wilhelm F, Winkler U, Bes s er S, Hirrlinger J (2012) Ca(2)(+) s ignals of as trocytes are modulated by the NAD(+)/NADH redox s tate. Journal of neurochemistry 120: 1014-1025 Reuken PA, Bruns T, Zimmer B, Michael A, Brunkhors t FM, Pletz MW, Stallmach A (2012) Recurrent fever and bacteraemia after endos copic variceal haemos tas is with cyanoacrylate: a cas e report. Infection 40: 351353 Reuken PA, Pletz MW, Baier M, Pfis ter W, Stallmach A, Bruns T (2012) Emergence of s pontaneous bacterial peritonitis due to enterococci - ris k factors and outcome in a 12-year retros pective s tudy. Aliment Pharmacol Ther 35: 1199-1208 Richter F, Bauer R, Ebers berger A, Lehmenkuhler A, Schaible HG (2012) Enhanced neuronal excitability in adult rat brains tem caus es wides pread repetitive brains tem depolarizations with cardiovas cular cons equences . J Cereb Blood Flow Metab Schmerler D, Neugebauer S, Ludewig K, Bremer-Streck S, Brunkhors t FM, Kiehntopf M (2012) Targeted metabolomics for dis crimination of s ys temic inflammatory dis orders in critically ill patients . Journal of lipid research 53: 1369-1375 Schmidt K, Mehlhorn J, Kaus che S, Schmücker K, Thiel P, Heintze C, Brunkhors t FM, Gens ichen J (2012) Pos tintens ive Nachs orge in der Haus arztpraxis . Medical special 6: 10-11 Schmidt K, Thiel P, Mehlhorn J, Mueller F, Gens ichen J (2012) Res iduen kritis cher Erkrankungen in der Haus arztpraxis . Intensiv- und Notfallbehandlung 37: 139-145 Schmitt M, Dietzek B, Neugebauer U, Krafft C, Rös ch P, Popp J (2012) Raman-Spektros kopie - der Weg zu einer labelfreien biomedizinis chen Diagnos tik. Endo heute 25: 262-267 Schubert H, Eis elt M, Walter B, Fritz H, Brodhun M, Bauer R (2012) Is oflurane/nitrous oxide anes thes ia and s tres s -induced procedures enhance neuroapoptos is in intrauterine growth-res tricted piglets . Intensive Care Med 38: 1205-1214 Schwarzkopf D, Meis s ner W, Wedding U, Riedemann NC, Pfeifer R, Fritzenwanger M, Günther A, Egerland K, Henkel M, Skupin H, Muecke M, Hartog CS (2012) Kommunikation im Team und Burnout: Eine Befragung von intens iv- und palliativmedizinis chen Pflegekräften und Ärzten zu Therapiebes chränkungen am Lebens ende. Z Palliativmed 13: 293-300 Sobke A, Klinger M, Hermann B, Sachs e S, Nietzs che S, Makarewicz O, Keller PM, Pfis ter W, Straube E (2012) The urinary antibiotic 5-nitro-8-hydroxyquinoline (Nitroxoline) reduces the formation and induces the dis pers al of Ps eudomonas aeruginos a biofilms by chelation of iron and zinc. Antimicrobial agents and chemotherapy 56: 6021-6025 Sponholz C, Hus e K, Kramer M, Giamarellos -Bourboulis EJ, Claus RA, Kern A, Engel C, Kuhnt E, Kiehntopf M, Routs i C, Mylona V, Ts angaris I, Heinemann SH, Reinhart K, Platzer M, Bauer M (2012) Gene polymorphis ms in the heme degradation pathway and outcome of s evere human s eps is . Shock 38: 459-465 Stallmach A, Hagel S, Bruns T, Bauer M (2012) Zu kurz gedacht: Aufgaben fur die Nachwuchs forderung in der klinis chen Fors chung. [Cut a long s tory too s hort: Challenges in clinical res earch]. Dtsch Med Wochenschr 137: 496-500 Tierney L, Linde J, Muller S, Brunke S, Molina JC, Hube B, Schock U, Guthke R, Kuchler K (2012) An Inters pecies Regulatory Network Inferred from Simultaneous RNA-s eq of Candida albicans Invading Innate Immune Cells . Front Microbiol 3: 85 Tzepi IM, Giamarellos -Bourboulis EJ, Carrer DP, Ts aganos T, Claus RA, Vaki I, Pelekanou A, Kots aki A, Tziortzioti V, Topouzis S, Bauer M, Papapetropoulos A (2012) Angiopoietin-2 enhances s urvival in experimental s eps is induced by multidrug-res is tant Ps eudomonas aeruginos a. The Journal of pharmacology and experimental therapeutics 343: 278-287 Vas s ilev T, Bauer M (2012) Pas s ive immunotherapy of s eps is with intravenous immune globulin: not all IVIg preparations are created equal. Crit Care 16: 407 Wachtler B, Citiulo F, Jablonows ki N, Fors ter S, Dalle F, Schaller M, Wils on D, Hube B (2012) Candida albicans http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016 Publikationen Seite 19/19 epithelial interactions : dis s ecting the roles of active penetration, induced endocytos is and hos t factors on the infection proces s . PloS one 7: e36952 Weber M, Lambeck S, Ding N, Henken S, Kohl M, Deigner HP, Enot DP, Igwe EI, Frappart L, Kiehntopf M, Claus RA, Kamradt T, Weih D, Vodovotz Y, Briles DE, Ogunniyi AD, Paton JC, Maus UA, Bauer M (2012) Hepatic induction of choles terol bios ynthes is reflects a remote adaptive res pons e to pneumococcal pneumonia. Faseb J 26: 2424-2436 Weimann A, Kern BR, Loffler M, Sablotzki A, Thiele F, Brunkhors t FM (2012) [Enrolment of intens ive care patients in clinical s tudies : Ethical, legal and organizational problems from an interdis ciplinary point of view.]. Medizinische Klinik, Intensivmedizin und Notfallmedizin 10.1007/s 00063-012-0153-7 Wils on D, Citiulo F, Hube B (2012) Zinc exploitation by pathogenic fungi. PLoS Pathog 8: e1003034 2011 Axer H, Romeike BFM, Brunkhors t F, Zinke J, Ringer TM, Günther A (2011) Neurological s equelae of s eps is : II) Neuromus cular weaknes s . The Open Critical Care Medicine Journal 4: 8-14 Bruns T, Peter J, Hagel S, Herrmann A, Stallmach A (2011) The augmented neutrophil res piratory burs t in res pons e to Es cherichia coli is reduced in liver cirrhos is during infection. Clinical and experimental immunology 164: 346-356 Bruns T, Peter J, Hagel S, Pfeifer R, Prinz P, Stallmach A (2011) Homozygous carrier of the NOD2 1007fs frames hift mutation pres enting with refractory community-acquired s pontaneous bacterial peritonitis and developing fatal pulmonary mucormycos is : A cas e report. Hepatology research : the official journal of the Japan Society of Hepatology 41: 1009-1014 Gonnert FA, Recknagel P, Seidel M, Jbeily N, Dahlke K, Bockmeyer CL, Winning J, Los che W, Claus RA, Bauer M (2011) Characteris tics of clinical s eps is reflected in a reliable and reproducible rodent s eps is model. The Journal of surgical research 170: e123-134 Hagel S, Brunkhors t F (2011) Seps is . Intensivmed Notfmed 1: 57-73 Hagel S, Bruns T, Herrmann A, Stallmach A, Schmidt C (2011) Abnormal Glucos e Tolerance: A Predictor Of 30Day Mortality In Patients With Decompens ated Liver Cirrhos is . Zeitschrift fur Gastroenterologie 49: 331-334 Kiehntopf M, Schmerler D, Brunkhors t FM, Winkler R, Ludewig K, Os terloh D, Bloos F, Reinhart K, Deufel T (2011) Mas s s pectometry-bas ed protein patterns in the diagnos is of s eps is /s ys temic inflammatory res pons e s yndrome. Shock 36: 560-569 Ringer TM, Axer H, Romeike BFM, Zinke J, Brunkhors t F, Witte OW, Günther A (2011) Neurological s equelae of s eps is : I) Septic encephalopathy. The Open Critical Care Medicine Journal 4: 2-7 Seider K, Brunke S, Schild L, Jablonows ki N, Wils on D, Majer O, Barz D, Haas A, Kuchler K, Schaller M, Hube B (2011) The facultative intracellular pathogen Candida glabrata s ubverts macrophage cytokine production and phagolys os ome maturation. J Immunol 187: 3072-3086 http://www.cscc.uniklinikum-jena.de/cscc/Publikationen Ausgabe: 23 Apr 2016
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