CV – Christian von Mering – 02/12/15 Curriculum Vitae Name: Birth: Citizenship: Address: Email: Website: Christian von Mering July 19th, 1971, in Munich German Feuerweg 11 8046 Zürich-Affoltern Switzerland [email protected] http://www.imls.uzh.ch/vmering/ Education / Employment since Aug. 2012: Full Professor of Bioinformatics, Institute of Molecular Life Sciences, University of Zurich, Switzerland. Aug. 2006 – July 2012: Associate Professor of Bioinformatics, Institute of Molecular Life Sciences, University of Zurich, Switzerland (‘Ausserordentlicher Professor ad personam’). Sep. 2001 – July 2006: Post-Doc and Staff Scientist (Computational Biology), at the European Molecular Biology Laboratory, Heidelberg (Group of Peer Bork). Aug. 2001: Jul. 1998 - Aug. 2001: May 1998: Dr.sc.nat. (Ph.D.) awarded from the University of Zurich, Switzerland Graduate studies at the University of Zurich, Molecular Biology Institute, under the supervision of Prof. Dr. Konrad Basler. Project Title: “Transfer of human Gli proteins into Drosophila melanogaster developing wing – evolutionary conservation of a developmental program” Diploma (Biochemistry) awarded from the Free University of Berlin, Germany. June 1997 - May 1998: Diploma work in Berlin and Zurich, under the supervision of Prof. Dr. Charles Weissmann, University of Zurich. Project Title: “Reverse Genetics of the Prion Protein through Adenovirus-mediated Gene Transfer” Oct. 1992 - June 1997: Undergraduate studies (Biochemistry) at the Free University, Berlin Aug. 1991 - Sep. 1992: Substitute Military Service (Zivildienst), working with mentally disabled children, at “Lebenshilfe e.V.”, Titisee-Neustadt, Germany June 1991: July 1989: Highschool Diploma (Abitur) from “Kreisgymnasium Hochschwarzwald”, Titisee-Neustadt, Germany Highschool Diploma from „Albert Lea Senior High School“, Albert Lea, Minnesota, USA CV – Christian von Mering – 02/12/15 Honors / Functions since June 2008: Associate Academic Editor at “PLoS Computational Biology” since May 2008: 1992 – 1998: Member of the Executive Board of the “Swiss Institute of Bioinformatics” (Geneva/Lausanne) Full Membership and Student Scholarship from “Studienstiftung des deutschen Volkes”, Berlin. Funding / Research Support • European Research Council (ERC), Starting Investigator Grant – Principal Investigator UMICIS – Uncultivated Microbes In Situ, a Computational Biology Approach. 1'150’000.- EUR, over five years + one year extension (2010-2016) • Swiss National Science Foundation 3100A0-118211 – Principal Investigator Microbial Network and their Functional Capabilities in the Environment. 440'000.- CHF, over three years (2008-2010) 537'000.- CHF, over three years + one year extension (2011-2015) 756'000.- CHF, over three years (2015-2017) • Swiss Institute of Bioinformatics STR08/11 – Principal Investigator The STRING database – known and predicted protein interactions for Systems Biology 530'000.- CHF, over four years (2008-2011) 1'140'000.- CHF, over five years (2012-2016) • SystemsX.ch – Co-Investigator PhosphoNetX: Phosphorylation-Modulated Informational Networks of the Cell InfectX: Systems Biology of Pathogen Entry into Human Cells TargetInfectX: Multi-Pronged Perturbation of Pathogen Infection in Human Cells 1’000'000.- CHF, in three RTD projects (2008-2016, 2009-2012, 2014-2015) Teaching Experience • Conceptualization and Implementation of the Curriculum for a new Masters Program: “Computational Biology & Bioinformatics”, a Specialized Joint Master at the ETH and the University of Zurich; ongoing participation in this Master’s Planning & Admissions Committee. • Lecture: “Functional Genomics” (three hours per week; Modulverantwortung) • Practical: “Bioinformatics and Programming” (with Profs. Wagner, Furrer, Shimizu, Robinson) • Block-Course: “Techniques in Computational Biology” (practicals for Biology graduate students; three full days; with Prof. K. Shimizu und A. Wagner, Modulverantwortung) • Lecturing at various summer schools and international block courses: including Cuernavaca, Mexico (for EMBO), Temasek Labs, Singapore (for EMBO) and Bertinoro, Italy (for the European Genetics Foundation). CV – Christian von Mering – 02/12/15 Publications 90 publications in total; these have been cited 20’563 times so far; Hirsch-index (“h-index”) is 49. The manuscripts considered the most important in recent years are listed below. Online, the full list is also available, at http://tinyurl.com/o2jmfjl * = equal contribution (or shared corresponding author) Szklarczyk D*, Franceschini A*, Wyder S, Forslund K, Heller D, Huerta-Cepas J, Simonovic M, Roth A, Santos A, Tsafou KP, Kuhn M, Bork P*, Jensen LJ*, von Mering C* STRING v10: protein-protein interaction networks, integrated over the tree of life. Nucleic Acids Res. 2015, 43:D447-52, doi: 10.1093/nar/gku1003. Wang MC, Herrmann CJ, Simonovic M, Szklarczyk D, von Mering C Version 4.0 of PaxDb: Protein abundance data, integrated across model organisms, tissues and cell-lines. Proteomics 2015, doi: 10.1002/pmic.201400441. Warinner C, Matias-Rodrigues JF, Vyas R, Trachsel C, Shved N, Grossmann J, Radini A, Hancock Y, Tito RY, Fiddyment S, Speller C, Hendy J, Charlton S, Luder HU, Salazar-García DC, Eppler E, Seiler R, Hansen L, Castruita JAS, Barkow-Oesterreicher S, Teoh KY, Kelstrup C, Olsen JV, Nanni P, Kawai T, Willerslev E, von Mering C, Lewis CM, Collins MJ, Gilbert TP, Rühli F*, Cappellini E*. Pathogens and host immunity in the ancient human oral cavity. Nature Genetics 2014, 46(4):336-44. Schmidt TSB, Matias-Rodrigues JF, von Mering C Limits to Robustness and Reproducibility in the Demarcation of Operational Taxonomic Units. Environmental Microbiology 2014, doi: 10.1111/1462-2920.12610. Franceschini A*, Meier R*, Casanova A*, Kreibich S*, Daga N, Andritschke D, Dilling S, Rämö P, Emmenlauer M, Kaufmann A, Conde-Alvarez R, Low SH, Pelkmans L, Helenius A*, Hardt WD, Dehio C, von Mering C*. Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens. PNAS 2014, 111(12):4548–4553. Matias-Rodrigues JF, von Mering C. HPC-CLUST: Distributed hierarchical clustering for very large sets of nucleotide sequences. Bioinformatics 2014, 30(2), 287-8. Chaffron S, Rehrauer H, Pernthaler J, von Mering C. A global network of coexisting microbes from environmental and whole-genome sequence data. Genome Research 2010, 20(7):947-959. von Mering C, Hugenholtz P, Raes J, Tringe SG, Doerks T, Jensen LJ, Ward N, Bork P. Quantitative phylogenetic assessment of microbial communities in diverse environments. Science 2007, 315(5815):1126-1130. Tringe SG*, von Mering C*, Kobayashi A, Salamov AA, Chen K, Chang HW, Podar M, Short JM, Mathur EJ, Detter JC, Bork P, Hugenholtz P, Rubin EM. Comparative metagenomics of microbial communities. Science 2005, 308(5721):554-557. von Mering C, Krause R, Snel B, Cornell M, Oliver SG, Fields S, Bork P. Comparative assessment of large-scale data sets of protein-protein interactions. Nature 2002, 417(6887):399-403
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