n
Tech
583
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224 221 220
117
Uferstraße
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Dept. of Medicine V
Hematology, Oncology, Rheumatology
Director & Chair: Anthony D. Ho
Molkenkur
Blum
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1.500
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April 1-2, 2016
Lecture hall, Medical Center, Department of Medicine
Im Neuenheimer Feld 410, 69120 Heidelberg
➜
710
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Tech
583
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307
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306
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151
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P29
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Hörsäle
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Geogr.
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Umweltphysik
229
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260
Kirschnerstraße
159
234
Geologie
231
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280
370
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115
153
H
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ZMBH
282
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330
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524
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Mathematik URZ
Südasieninstitut
400
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Völkerrecht
535
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Hochschule
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PVZM Süd
536
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Olympiastützpunkt Rhein-Neckar
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Institut für Sport und
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March 31 – April 2, 2016
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Stem Cell Therapy –
Facts and Myths
3.000 €
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Please register via E-mail by February
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241 222
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March 31, 2016
Neue Aula, Universität Heidelberg
Universitätsplatz, 69117 Heidelberg
➜
Berlinerstraße
Berlinerstraße
Mönchh
505
Neubau Mathematikon
232
Hörsäle
Chemie
he
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232
505
506
227
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Heuscheuer
129
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9
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320
Kirschnerstraße
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370
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151
P35
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Nicole Opitz
H
P
P18
E-mail: [email protected]
19
P
21
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Im Neuenheimer
Feld 410 | 69120 Heidelberg
P
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Phone: +49 6221
56-8001 | Fax: +49 6221 56-5813
36
P
Christiane Wickenhöfer
22
E-mail: [email protected]
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Gästehaus
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Conference Locations
7051
Geogr.
Institut
Alte Brücke
155
304
Botan
te
Zoologisches
Institut
230
Umweltphysik
267
229
Physik
Mensa
234
Geologie
231
tu
Heiligenbergturm
Brückenstraße
152
78
sti
Römerstraße
09:55 – 10:15 Jan Lohmann, Heidelberg
Control of stem cell identity:
Lessons from plants
M
360
rstr
aße
iste
-2
In
e
09:35 – 09:55 Wolfgang Wagner, Aachen
How to keep your stem cells young – DNA methylation changes in aging
fme
154
324
344a
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0
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Anne-Claude Gavin, Heidelberg
Omics profiling of HSC niche
Ho
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305
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Ch
enth
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Fehre
Aging and Disorders of Stem Cells
Chairpersons: Harald Klüter,
Jeroen Krijgsveld
306
365
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236
Mineralogie
235
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alstra
Ernst-WalzBrücke
Key-note lecture
Werner Franke, Heidelberg
Wild and at random: Spontaneous and cumulative syntheses of epithelial
molecules in various hematopoietic cells
307
326
Stauwehr
08:30 – 09:15
Session 8
09:15 – 09:35
im
Lecture hall, Medical Center, Department of Medicine
Im Neuenheimer Feld 410, 69120 Heidelberg
327
346
253/
254
288
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traß
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➜
347
366
364
521
501
Contact
Hörsaal
308
Mathem.
328
Institut
367
Neubau
524
523
Wohnheime
522
503
502
Phys.Chemie
293/
292
294
27
348
Chirurgie
161
nn
Saturday, April 2, 2016
Mathematik URZ
Südasieninstitut
368
MPI für
Völkerrecht
535
504
500
330
350
536
560
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PVZM Süd
Med
Klin .
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Key-note lecture
Richard Champlin, Houston, USA
Advances with alternative donors:
Now everyone can get a transplant
561
Pädagogische
Hochschule
Marsilius-Arkaden
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699
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17:00 – 17:45
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460
400
10:15 – 10:35 Andreas Trumpp, Heidelberg
430
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Molecular and cellular control
of450normal and leukemic stem cells 440
410
10:35 – 11:00 Coffee break
H
P
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Session 9
Clinical Applications
ZOO
H
P
60
Chairpersons: Hanns-Martin Lorenz,1
153
Konrad Kohler
11:00 – 11:20 Jakob van Laar, Utrecht, Netherlands
Stem cell therapy in autoimmune disease – the facts
11:20 – 11:40 Michael Andreeff,
Houston, USA
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Leukemia stemFlucells
ghafe im
A 656 n
Wieblinge
11:40 – 12:00 Hartmut Goldschmidt, Heidelberg
r Weg
Role of autologous transplantation in pursuit of a cure
Session 10
Evolution of Cellular Immunotherapy
Chairpersons: Michael Schmitt,
Eric Rosenbaum
12:00 – 12:20 Hans-Jochem Kolb, München
Evolution of cellular immunotherapy after the first DLI
12:20 – 12:40 Gerhard Ehninger, Dresden
The future of transplantation and cell therapy
12:40 – 13:00 Klaus Cichutek, Langen
Stem cell based medicinal products – hopes and reality
13:00 – 13:45 Key-note lecture
Malcolm Brenner, Houston, USA
Driving CAR-T cells beyond B-cell malignancy
13:45 – 14:45 Lunch
DJH
P3
H
LIZ 1 165
16:40 – 17:00 Hartmut Döhner, Ulm
Genetics for guiding patient care in AML
672
114
676 - 683
670
115
Wohnheime
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16:20 – 16:40 Michael Pfreundschuh, Homburg
Stem cell transplantation in aggressive lymphomas: Do we still need it ?
669
DKFZ
P
530
Technologiepark 515
P6
671
581
580
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traß
nds
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she
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16:00 – 16:20 Rüdiger Hehlmann, Mannheim
Cure of CML: Are we there yet ?
P5
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stw
POb
584
582
516-519
Hubschrauberlandeplatz
Sportanlagen Universität
ße
nstra
garte
Tier
Schwimmbad
520
Do
ss
en
fad
senp
Klau
7050
700
Institut für Sport und
Sportwissenschaft
Hau
Scientific Program
Dear Colleagues and Friends,
May I extend a cordial invitation to you to a Special Symposium „Stem Cell Therapy – Facts and Myths“ to be held
from March 31, 2016 to April 2, 2016 in Heidelberg.
The Department of Medicine V (Hematology, Oncology &
Rheumatology), Ruprecht-Karls-University, Heidelberg,
Germany, will be celebrating the 30th anniversary of the
first successful transplantation using hematopoietic stem
cells (HSC) derived from peripheral blood instead of the
bone marrow, performed 1985 and published in February
1986. Ever since then, stem cell research and stem cell
transplantation have remained a major component of the
Department.
In addition, the Baden-Württemberg Foundation has organized a satellite symposium on the March 31 in the Neue
Aula to earmark twelve years of promotion and support for
adult stem cell research in the State of Baden-Württemberg.
This is followed by the main scientific symposium from
April 1 to April 2, 2016, at the Department of Medicine,
Medical Center of the University.
With kindest regards,
Thursday, March 31, 2016
Satellite Symposium of the Baden-Württemberg Foundation
www.bwstiftung.de
➜
Neue Aula, Universität Heidelberg
Universitätsplatz, 69117 Heidelberg
Opening
08:30 – 08:35 Christoph Dahl, Managing Director,
Baden-Württemberg Foundation
08:35 – 08:40 Wolfgang Herzog,
Dean Faculty of Medicine, Heidelberg
Session 1
Stem Cells and Niche
Chairpersons: Alwin Krämer, Stephan Meuer
08:40 – 09:05 Petra Boukamp, Heidelberg
The niche: A determinant for stem cell
maintenance and function in normal skin and skin carcinomas
09:05 – 09:30 Xi Xi He, Kansas City, USA
Dynamic interaction between tumor
initiating cells and immune response
09:30 – 09:55 Gerd Klein, Tübingen
Molecular and biophysical characterization of the human hematopoietic stem cell niche
Anthony D. Ho, MD, FRCPC
Professor & Chair
Department of Medicine V
Ruprecht-Karls-University
Heidelberg
09:55 – 10:20 Lenhard Rudolph, Jena
Mechanisms and targets to improve function and genetic stability of hematopoietic stem cells at aging
10:20 – 10:50 Coffee break
Session 2
Neuronal Stem Cells, Mitochondrial Damage
Chairpersons: Anna Wobus, Christof von Kalle
10:50 – 11:15 Francesca Ciccolini, Heidelberg
Quiescent stem cells in the adult
mammalian brain
11:15 – 11:40
11:40 – 12:05
12:05 – 12:50
Oliver Rothfuss, Tübingen
Akt dependent regulation of self renewal in pluripotent stem cells
Verdon Taylor, Basel, Switzerland
Notch surprises in brain tumor formation and neural stem cell fate
Key-note lecture
Toshio Suda, Tokyo, Japan
Controlling growth and maturation of blood stem cells
12:50 – 14:15 Lunch break
Session 3
Hematopoietic Stem Cells and iPS
Chairpersons: Motomu Tanaka,
Rupert Handgretinger
14:15 – 14:40 Karin Scharffetter-Kochanek, Ulm
Mesenchymal stem cells promote tissue repair
14:40 – 15:05 Hanno Glimm, Heidelberg
Functional and genetic heterogeneity in gastrointestinal cancers
15:05 – 15:30 Jochen Utikal, Mannheim
Differentiation of induced pluripotent stem cells into cutaneous lineages
15:30 – 15:55 Claudia Lengerke, Basel, Switzerland
The significance of selected stem cell pro-
teines for the tumor biology of breast cancer
15:55 – 16:45 Key-note lecture
Armand Keating, Toronto, Canada
MSC for regenerative medicine, the way forward
Friday, April 1, 2016
➜
Lecture hall, Medical Center, Department of Medicine
Im Neuenheimer Feld 410, 69120 Heidelberg
08:30 – 09:15
Session 4
09:15 – 09:35
Key-note lecture
Hans Schöler, Münster
Small organs, great potential:
Recent advances in stem cell research
Molecular Fundaments of Stem Cells
Chairpersons: Peter Krammer,
Konrad Beyreuther
Michael Boutros, Heidelberg
Reading and writing in the genome
09:35 – 09:55 Jochen Wittbrodt, Heidelberg
Stem cells in growth and regeneration of the retina
09:55 – 10:15
10:15 – 10:45
Session 5
10:45 – 11:05
Christof Niehrs, Mainz
Not so canonical Wnt signaling
Coffee break
Stem Cells and Niche
Chairpersons: Hannah Monyer,
Jürgen Hescheler
Tsvee Lapidot, Rehovot, Israel
Metabolic regulation of blood and bone forming stem cells: The role of ROS and nitric oxide
11:05 – 11:25 Linheng Li, Kansas City, USA
Maintaining normal and targeting leukemia stem cells
11:25 – 11:45 Suzanne Watt, Oxford, UK
Vascular niche and hematopoietic
regeneration
11:45 – 12:05 Hellmut Augustin, Heidelberg
Angiocrine signaling during tissue homeo-
stasis and in the bone marrow stem cell niche
12:05 – 12:25 Albrecht Müller, Würzburg
Polycomb function in ESCs and HSCs
12:25 – 14:00 Lunch break
Session 6
Clinical Transplantations – the Way Forward
Chairpersons: Rainer Haas,
Klaus-Michael Debatin
14:00 – 14:20 Peter Dreger, Heidelberg
Novel trends in allogeneic stem cell
transplantation
14:20 – 14:40
Dai-Hong Liu, Bejing, China
Unmanipulated haploidentical PBSCT for high-risk hematologic malignancies:
Outcomes and feature of GVHD compared with matched related PBSCT
14:40 – 15:00 Helen Heslop, Houston, USA
Engineered cell therapy coming of age
15:00 – 15:20 Nicolaus Kröger, Hamburg
Targeting MRD post transplant
15:20 – 15:40 Ted Ball, San Diego, USA
Checkpoint inhibition for treatment of relapse after allogeneic stem cell
transplantation
15:40 – 16:00 Coffee break
Session 7
Clinical Transplantations –
becoming obsolete?
Chairpersons: Bernd Dörken,
Wolf-Karsten Hofmann