Appendix C Application of Dynamic Swallowing Simulation applying WKA-2 C.1 Purpose Swallowing, known scientifically as deglutition, is the process in the human or animal body that makes something pass from the mouth, to the pharynx, and into the esophagus, while shutting the epiglottis, as shown in Fig. C.1. If this fails and the object goes through the trachea, then choking or pulmonary aspiration can occur as shown in Fig. C.2. In the human body it is controlled by the swallowing reflex [125]. Dysphagia (aspiration) is the medical term for symptoms of difficulty in swallowing [126][127]. Some patients have limited awareness of their own dysphagia, so lack of symptoms does not exclude an underlying disease [128]. When dysphagia goes undiagnosed or untreated, patients are at a high risk of aspiration and subsequent aspiration pneumonia secondary to food or liquids going the wrong way into the lungs [129]. One of the most important causes of aspiration is the spillage of food and liquid into the pharynx. It has been stated that normal subjects can hold food bolus in the mouth without spillage in any head posture. Even if a slight spillage occurs, aspiration following spillage will not occur because a swallowing reflex starts soon after spillage. As the start of the reflex is delayed in patients with dysphagia, spillage becomes a risk factor of aspiration [130]. For these reasons, a lot of researchers have tried to evaluate and diagnose the causes of dysphagia in individual patients to determine appropriate therapies. 301 盧 博士論文 Video Fluorographic Swallowing Study (VFSS) is the gold standard for evaluating the mechanism of swallowing. For this study, the patient is seated comfortably and given foods mixed with barium to make them radiopaque [131][132]. The patient eats and drinks these (a) (b) Figure C.1 Endoscopic image (a) Before aspiration with food bolus (b) Aspiration with food bolus (a) (b) Figure C.2 Larynx and epiglottis (a) Clinical image captured by fluoroscopic unit (b) Anatomical position of epiglottic vallecula (arrow) 302 Application of Dynamic Swallowing Simulation Applying WKA-2m Patient or Oralpharyngeal model Fluoros copic unit model Food bolus (a) (b) Figure C.3 Video fluorographic swallowing study (VFSS) (a) Fluoroscopic unit (b) Image captured by Fluoroscopic Pharyngeal wall Back Epiglottis Tongue Front Tongue Front (a) (b) Figure C.4 in-vitro VFSS simulation system created by gypsum (a) Integration of CT image (b) 3D gypsum model foods while radiographic images are observed on a video monitor and recorded on videotape. Using the VFSS, the author can evaluate and diagnose the causes of dysphagia as shown in Fig. C.3. There are many therapies to reduce dysphagia, such as swallowing therapy, surgery, and dietary modification [133]. In our study, the author focus on dietary modification, a common treatment approach [134]. Normally, swallowing is affected by food bolus properties 303 博士論文 盧 Food Bolus Figure C.5 Image captured by Fluoroscopic unit using 3D gypsum model such as hardness, stickiness and rheological characteristics. Dietary modifications can prevent dysphagia in swallowing disorder patients, as well as promote good nutrition. Based on these facts, our goal is to find food which prevents dysphagia, and develop food for swallowing disorder patients accordingly. For dietary modification testing, the patient eats food boluses (mixed with barium to make them radiopaque) which have different characteristics while radiographic images are observed on a video monitor and recorded on videotape (Figure C.3). Then, doctors evaluate and diagnose whether there is a risk of aspirating the food boluses or not. However, performing these experiments with actual patients is too risky, and also presents ethical problems. Therefore the author are proposing an in-vitro VFSS simulation system. So far the author have studied dietary modification possibilities using the in-vitro VFSS simulation system. From each of the CT images, the author create 3D models, and based on the 3D models, the author manufacture a plaster model as shown in Fig. C.4. As experimental conditions, viscosity and head position were set. While radiographic images are observed on a video monitor and recorded on videotape, foods mixed with barium to make them radiopaque are passed down from the oral cavity to the epiglottis as shown in Fig. C.5. The data from this simulation might facilitate estimation of the optimal food viscosity and feeding position that would allow such patients to eat without aspiration [135]. However, the proposed VFSS simulation system is static and the simulation data can not provide quantitative information because it can not realistically simulate the act of swallowing. Swallowing requires not only dynamic motion of the tongue, but also simultaneous motion of the mandible. Therefore, in order to realistically simulate the act of 304 Application of Dynamic Swallowing Simulation Applying WKA-2m (a) (b) Figure C.6 Dynamic VFSS simulation system (a) Lateral view (b) Frontal view swallowing, the author is proposing an in-vitro dynamic VFSS simulation system. It consists of a head, mandible, neck, tongue, trachea, larynx, pharynx and 16 actuators with wire driving mechanisms. This system can simulate swallowing by moving the tongue and mandible simultaneously. Just as with the static VFSS simulation system, a set of experiments can be carried out with different viscosities and different head positions while radiographic images are observed on a video monitor and recorded on videotape. 305 盧 博士論文 Figure C.7 Detail of the wiring mechanism with their corresponding human muscle. In this paper, the author will present our design concept for an in-vitro VFSS dynamic simulation system, and its hardware configuration. Finally, the author will present a set of swallowing experiments carried out using the dynamic VFSS simulation system, four food boluses with different viscosities, and movie clips captured using the Video Fluoroscopy (VF) unit. C.2 Method The design concept of the dynamic VFSS simulation system assumes four requirements: first, the proposed system should assume patients with severe swallowing disorder. Second, the proposed system should reproduce the physiology and anatomy of the organs involved in swallowing. The third principle is that the system should be capable of simulating swallowing. Finally, an accurate positioning control should be implemented to assure that the task conditions are precisely reproduced. As a result, the dynamic VFSS simulation system contains six active degree of freedoms (DOFs). Such actuation systems 306 Application of Dynamic Swallowing Simulation Applying WKA-2m (a) (b) (c) Figure C.8 3 Tongue model extracted by CT image (a) One layer of CT images (b) Extraction of one layer of one layer of CT image (c) Integration of each of the layers of extracted parts (a) (b) Figure C.9 Manufacture of Tongue, larynx, and trachea (a) Tongue manufactured by 3D printer for the prototype (b) Tongue manufactured by silicon for the simulation system have been designed to control the positioning of the 16 wire driving mechanisms that reproduces the swallowing. In particular, the wire driving mechanisms were designed to control the motion of the following muscles (Figure C.6-7): lateral pterygoid muscle, masseter muscle, infrahyoid muscles, temporal muscle, and suprahyoid muscle. In order to reproduce the swallowing motion, the author have designed simulated organs by considering the range of motion of human organs. In particular, the author reproduced the motion range of the 307 盧 博士論文 (a) (b) Figure C.10 Range of mandible of human and dynamic simulation system (a) Range of human mandible (b) Range of the mandible of the dynamic simulation system mandible and tongue as closely as possible. For this purpose, the author has collected information from medical literature as well as from MRI images. C.2.1 Configuration of Hardware Each part of the Dynamic VFSS simulation system, such as the head, mandible and tongue, is designed based on CT images, and has been redesigned with embedded actuation systems (Figure C.8-11). In particular, the simulation system has been designed to reproduce the motion of the tongue, and the mandible. The actuation system of the simulation system is based on a wire driving system, so that it fits into a human-size model. The wire driving system consists of sixteen Teflon-coated wires (which have a low friction coefficient), pulleys and RC servo motors (placed on a base). The wire driving mechanisms are shown in detail in Fig. C.6-7. The details of these mechanisms are as follows: a) Mandible Humans have a large DOF for chewing food. For the swallowing motion, 2-DOFs is sufficient to simulate with rotational motion (Ө) and translational motion (L). As shown in Fig. C.10a, the range of motion of the mandible is equivalent with that of human [83]. In order to control the motion of the mandible, the author has attached six wires to it. In addition, three 308 Application of Dynamic Swallowing Simulation Applying WKA-2m Figure C.11 Simplified 6 links model and arrangement of 16 wires common wires were connected with the mandible and tongue. For the kinetic axis, the author attached two linear guides. On the linear guides, the author also attached rotational axis (see Fig. C.6-7). b) Tongue In order to control the position of the tongue, the author considered three points: the tongue bone (hyoid bone), the center point of the tongue, and tip of the tongue. The actuation mechanism of the tongue has six wires attached to the tongue bone, three to the center point of the tongue and one to the tip of the tongue (Figure C.7). As the author has previously mentioned, three of those wires are common with the mandible, so the motion of the tongue is connected to that of the mandible. As it is shown in Fig. 11a, the range of motion of the hyoid bone is equivalent with that of a human [86]. In order to control the motion of tongue, the author must control the position of the tongue bone. On the other hand, in order to modify the shape of the tongue, the author must control the center point and tip. Of course, controlling the position of the center point and the tip of the tongue is dependent on the position of the 309 盧 博士論文 Figure C.12 Measurement device for test food texture analysis tongue bone. By using these controls to modify the shape of the tongue, the author may reproduce an oral cavity space appropriate for the swallowing motion. c) Epiglottis and Pharynx The epiglottis and pharynx play an important role in swallowing. During this process, the larynx rises, the pharynx is narrowed, and the epiglottis, which is composed of cartilage, covers its opening and directs food and fluid into the esophagus simultaneously, blocking entry into the trachea which would then lead to the lungs. However, the author assume that patients have severe swallowing disorder which is called severe dysphagia. In such patients, the epiglottis does not close as it should, the larynx does not rise so much, and the pharynx is not narrowed at the same time. Finally, food or liquid may enter the windpipe and become Table C.1 Characterisitics of test foots Test food Barium Barium with food thickener Custard pudding Rice porridge Hardness (Pa) 90 Stickiness (J/m3) 7 300 30 900 1500 10 200 310 Application of Dynamic Swallowing Simulation Applying WKA-2m Figure C.13 Video fluoroscopy unit and dynamic VFSS simulation system maxilla soft palate mandible pharyngeal space epiglottis hyoid bone trachea esophagus epiglottic vallecula (residue of food bolus) (a) (b) Figure C.14 Image captured by video fluoroscopy unit (a) Lateral fluoroscopy view (b) Frontal oblique view trapped, causing choking. The author call this epiglottic dysfunction [136][137]. For these reasons, the epiglottis and the pharynx of the simulation system has no actuation, and has no wire driving mechanism, as shown in Fig. C.9. Epiglottis and pharynx play an important role in the swallowing procedure. During swallowing, the larynx rises and the epiglottis, which is composed of cartilage, covers its opening which then directs food and fluid into the esophagus and preventing its entry into the trachea which would then lead to the lungs. However, in the patient who has swallowing disorder, the epiglottis does not close as it should food or liquid may enter the windpipe, causing choking or trapping of food. The author calls 311 博士論文 盧 Table C.2 Result of experiments Test food Time distance of slip down Barium 0.2 Barium with food thickener Custard pudding Rice porridge 3.5 1.8 9.6 Weight (% of Residual volume) (SD) 11.7 (7.7) Area of Residual (mm2) (SD) Lateral Frontal View View 43.7 56.8 (8.6) (19.9) 62.4 (20.2) 123.1 (13.1) 232.9 (59.1) 52.8 (10.1) 75.8 (9.6) 130.7 (34.9) 162.9 (20.1) 207.6 (20.4) 254.0 (77.0) Density of Residual (% of gray level) Lateral View Frontal View 23.8 22.5 27.5 22.1 26.4 26.2 31.7 25.1 this epiglottic dysfunction [136][137]. For these reasons, the epiglottis of the simulation system has no actuation, and has no wire driving mechanism as shown in Fig. C.9. d) Kinematic Model, Patterns Generation and Control of Dynamic VFSS Simulation System In order to simulate the swallowing motion using our simulation system, the author should analyze the kinematic model of the simulation system for position control. In human anatomy, the motion of the tongue and the vocal cord follows the motion of the mandible because all of the tongue muscles are attached to the mandible. As a result, the author can simplify their motions into 6 DOF Link model as shown in Fig C.12. In order to simulate the swallowing motion, the author propose two coordinate systems, such as one absolute coordinate system O’ and one relative coordinate system O”, shown in Fig. C.12. First, the author adjust the position of the tongue Po’’(xo”, yo”), θ0, θ1 with respect to the relative coordinate, and the position of the mandible θ2, d0 with respect to the absolute coordinate as shown in Fig. C.12. Then, from the kinematic model of the simulation system, the author can obtain the center points of each of the pulleys on the head, the center points of each of the bearing units on the mandible, and the center points of each of the pulleys on the chest. Moreover, the author can also obtain the three points (tongue bone, center point, and tip of the 312 Figure C.15 Result of VFSS simulation (a) Custard pudding (b) Thickened liquid 313 (b) (a) Application of Dynamic Swallowing Simulation Applying WKA-2m 盧 博士論文 tongue) on the tongue. Based on these obtained points, the author can calculate each of the wire lengths, as shown in Fig. C.12. The swallowing motion especially a normal swallowing reflex is so complicate and quick. In comparison with normal human, motion of our robot is very slow. The author highlighted the motion pattern of mandible and hyoid bone in patients with severe dysphagia. C.3 Result and Discussion As stated in the introduction, as the start of the reflex is delayed in patients with dysphagia, spillage becomes a risk factor of aspiration. It is meaningful if the robot could simulate the relationship between the abnormal motion patten of hyoid bone, texture of the food and the occurrence of aspiration. For the purpose of this simulation, the author used the Dynamic VFSS simulation system with four food boluses which have different properties such as hardness, stickiness and rheological characteristics. From the result of the experiments, the author are trying to find the food bolus which does not cause dysphagia and develop food for swallowing disorder patients accordingly. In our experiments, the author used four test foods: barium, barium with food thickener, custard pudding, and rice. While the simulation system swallows the four test food boluses, the author observe movie clips captured by a VF unit to analyze and evaluate the four test foods and determine which food boluses cause dysphagia (aspiration). C.3.1 Measurement of Food Texture and Video Fluoroscopy Using a device to measure food texture (Figure C.13), the author obtained data about the characteristics of the four test food boluses such as hardness and stickiness, as shown in Table 1. In addition, the author uses a VF unit in order to analyze and evaluate the test food boluses during swallowing, as shown in Fig. C.14. This VF unit captures the lateral fluoroscopic view as well as the frontal oblique view, as shown in Fig. 15. 314 Application of Dynamic Swallowing Simulation Applying WKA-2m C.3.2 Video Fluoroscopy Swallow Study (VFSS) Simulation The author prepared four test foods. a) Barium contrast medium, b) Barium contrast medium with food thickening agent, c) Barium custard pudding, and d) Iodic contrast medium coated rice porridge. Before inserting the four test foods into the oral cavity, the author form them into food boluses, round or oval-shaped masses of food which are usually formed in the mouth after thorough chewing. Then, the author place one of the food boluses on the center of tongue with artificial saliva (Saliveht®, Teijin Pharma Tokyo, Japan to simulate the condition of oral mucosa), as shown in Fig. C.16. Then simulation of the swallowing motion begins. The experiments show us the ratio of residue, the time required for the test food to travel down, the area of residual foods in the lateral and the frontal images, and the gray-value density of the image as shown in Table C.2. The higher viscosity foods flowed slowly down the base of the tongue, and caused more residues because they flowed as a mass. Liquids, on the other hand, flowed rapidly and diffusely, leaving less residue. Barium with food thickener, custard pudding and rice porridge slid down the throat as a bolus (Figure C.16a). On the other hand, liquid barium flowed down quickly and made a splash, leaving little residue (Figure C.16b). Regarding the relationship between the amount of residues and the area in the VFSS images, the frontal oblique view showed a better correlation than the lateral view. No apparent correlation was seen between the type of the test food and the image density of residues. C.4 Conclusion The results from these experiments revealed that thickened boluses have a tendency to leave residue in the epiglottic vallecula. As in case of the liquid, fewer residues occur, and the risk of penetration to the larynx and aspiration is increased. This study shows that not only the lateral image but also the frontal image is important for evaluating the food residues in the oral- pharyngeal space. In the future, additional experiments will be carried out with a greater variety of different foods to find out which ones cause aspiration, and the author would like to propose a set of the experiments to see whether the orientation of the head andneck can affect aspiration or not. Moreover, motion of tongue, epiglottis, soft palate, and pharyngeal wall will take under consideration in future study. In our dynamic FDSS simulation system, the author 315 盧 博士論文 found several problems. Each of the wires slackened while applying position control. This caused position errors in the mandible and tongue. In the future, such errors should be evaluated and minimized. The author will propose wire tension controls on each of wire in order to prevent slack, and include embedded tensions sensors to do so. 316 Reference [1] Amitai Ziv, Paul Root Wolpe, Stephen D. Small, and Shimon Glick, “SimulationBased Medical Education: An Ethical Imperative,” Academicmedcine, vol.78, no.8, pp783-788, 2003. [2] Lynoe N, Sandlund M, Westberg K, Duchek M., “Informed consent in clinical training: patient experiences and motives for participating,” Journal of Med Educ., vol. 32, no. 5, pp. 465–471, 1998. [3] Hayes GJ. “Issues of consent: the use of the recently deceased for endotracheal intubation training,” Journal of Clin Ethics, vol. 5, no. 3, pp. 264–266, 1994. [4] Kaldjian LC, Wu BJ, Jekel JF, Kaldjian EP, Duffy TP., “Insertion of femoral vein catheters for practice by medical house officers during cardiopulmonary resuscitation,” New England Journal of Medicine, vol. 341, no. 27, pp. 2088–91, 1999. [5] Feinstein, AR. System, supervision, standards, and the epidemic of Dreyfus HL, Dreyfus SE. Mind over Machine: The Power of Human Intuition and Expertise in the Era of the Computer, New York: Gxford U Press, MacMillan, 1986. [6] OED Inc., [Online]. Available: http://dictionary.oed.com. 317 盧 博士論文 [7] Tjomsland N, Baskett P., “Resuscitation greats: Asmund S Lærdal,” Journal of Resuscitation, vol. 53, no. 2, pp115–119, 2002. [8] Abrahamson S, Denson JS, Wolf RM., “Effectiveness of a simulator in training anaesthesiology residents,” Journal of Med Educ., vol. 44, no. 6, pp. 515–519, 1969. [9] Abrahamson S, Denson JS, Wolf RM., “Effectiveness of a simulator in training anaesthesiology residents,” Journal of Qual Saf Health Care, vol. 13, no. 5, pp. 395– 397, 2004. [10] Gaba DM, DeAnda A., “A comprehensive anaesthesia simulation environment: recreating the operating room for research and training,” Journal of Anaesthesiology, vol. 69, no.3, pp. 387–394, 1988. [11] Good ML, Gravenstein JS., “Anaesthesia simulators and training devices,” Journal of International Anesthesiology Clinics, vol. 27, no.3, pp. 161–166, 1989. [12] Gaba DM, Howard SK, Fish KJ, Smith BE, Sowb YA., “Simulation-based training in anaesthesia crisis resource management (ACRM): a decade of experience,” Journal of Simulation Gaming, vol. 32, no. 2, pp. 175–193, 2001. [13] General Medical Council, Tomorrow’s Doctors: Recommendations on Undergraduate Medical Education, London, GMC, 1993. [14] Association of American Medical Colleges, “Learning objectives for medical student education – guidelines for medical schools: Report 1 of the Medical School Objectives Project,” Journal of Academic Medicine, vol. 74, no. 1, pp. 13–18, 1999. [15] Accreditation Committee, “Assessment and Accreditation of Medical Schools: Standards and Procedures,” Canberra: Australian Medical Council 2002. 318 Referencem [16] World Federation for Medical Education., “Global Standards for Quality Improvement. Copenhagen: WFME 2003. Bligh J. The clinical skills unit. Postgrad,” Journal of Medicinal Chemistry, vol. 71, no. 842, pp. 730–732, 1995. [17] Bradley P, Bligh J., “One year’s experience with a clinical skills resource centre,” Journal of Med Educ., vol. 33, no. 2, pp.114–120, 1999. [18] Dacre J, Nicol M, Holroyd D, Ingram D., “The development of a clinical skills centre,” Journal of Coll Physicians Lond, vol. 30, no. 4, pp. 318–324, 1996; [19] Ziv A, Wolpe PR, Small SD, Glick S., “Simulation-based medical education: an ethical imperative,” Journal of Academic Medicine., vol. 78, no. 8, pp.783-788, Aug. 2003. [20] Walls, R.M., Murphy, F., Luten, R.C., Schneider, E.C., Manual of Emergency Airway Management, 2nd Edition, Philadelphia: LIPPINCOTT WILLIAMS and WILKINS, 2004 [21] Solis, J, “Robotic Control Systems for Learning and Teaching Human Skills,” Ph.D. dissertation, Perceptual Robotics Laboratory, Scuola Superiore Sant’Anna, Pisa, Italy, 2004. [22] Solis, J., Marcheshi, S., Frisoli, A., Avizzano, C.A., Bergamasco, M.,“Reactive Robots System: An active human/robot interaction for transferring skills from robot to unskilled persons,” Advanced Robotics Journal, vol. 21, no. 4, pp. 267-291, 2007. [23] Owen, H., Follows, V., Reynolds, K., Burgess, G., Plummer, J., “Learning to apply effective cricoid pressure using a part task trainer,” Journal of Anaesthesia, vol. 57, no. 11, pp. 1098-1101, 2002. [24] Laerdal Medical Inc., [Online]. Available: http://www.laerdal.com/simman/simman.htm. 319 盧 [25] 博士論文 N. D. Syroid, J. Agutter, F. A. Drews, D. R. Westenskow, R. W. Albert, J. C. Bermudez, D. L. Strayer, H. Prenzel, R. G. Loeb, and M. B.Weinger, “Development and evaluation of a graphical anesthesia drug display,” Journal of Anesthesiology, vol. 96, no. 3, pp. 565-574, 2002. [26] D. M. Gaba, S. K. Howard, B. Flanagan, B. E. Smith, K. J. Fish, and R. Botney, “Assessment of clinical performance during simulated crises using both technical and behavioral ratings,” Journal of Anesthesiology, vol. 89, no. 22, pp. 8-18, 1998. [27] F. A. Drews, N. Syroid, J. Agutter, D. L. Strayer, and D. R.Westenskow, “Drug delivery as control task: Improving performance in a common anesthetic task,” Journal of Human Factors, vol. 48, no. 45, pp. 85-94, 2006. [28] S. B. Wachter, K. Johnson, R. Albert, N. Syroid, F. Drews, and D.Westenskow, “The evaluation of a pulmonary display to detect adverse respiratory events using high resolution human simulator,” Journal of the American Medical Informatics Association, vol. 13, no. 6, pp. 635-642, 2006. [29] N. Segall, J. M. Taekman, J. B. Mark, G. Hobbs, and M. C. Wright, “Coding, visualizing, and analyzing eye tracking data in simulated anesthesia care,” Proceedings of the 51st Annual Meeting of the Human Factors and Ergonomics Society, pp. 670-675, 2003. [30] M. C. Wright, J. M. Taekman, and M. R. Endsley, “Objective measures of situation awareness in a simulated medical environment,” Journal of Quality and Safety in Health Care, vol. 13, no. 7, pp. 165-171, 2004. [31] Martin, J.L, Bucx, M.J.L., van de Vegt, M.H, Snijders C.J., Stijnen, T., Wesselink, P. “Transverse forces exerted on the maxillary incisors during laryngoscopy,” Canadian Journal of Anaesthesia, vol. 43, no. 7, pp. 665-671, 1996 320 Referencem [32] Mayrose J., Kesavadas T., Chugh K., Dhananjay J., Ellis D.G.,“Utilization of Virtual Reality for Endotracheal Intubation Training,” Journal of Resuscitation, vol. 59, no. 1, pp. 133-138, 2003. [33] Burt, D. “Virtual reality in anaesthesia,” British Journal of Anesthesia, vol. 75, no. 4, pp. 472-480, 1995. [34] Aizuddin, M., Oshima, N., Midorikawa, R., Takanishi, A. “Development of Sensor System for Effective Evaluation of Surgical Skills,” Proceedings of the International Conference on Biomedical Robotics and Biomechatronics, ID 287, 2006. [35] Nobuki Oshima, Muhamad Aizuddin, Ryo Midorikawa, Jorge Solis, Yu Ogura, Atsuo Takanishi, “Development of a Suture Training Simulator with Quantitative Evaluation Function,” Proceedings of 5th International Special Topic Conference on Information Technology Applications in Biomedicine, IO 104, 2006. [36] Nobuki Oshima, Muhamad Aizuddin, Ryu Midorikawa, Jorge Solis, Yu Ogura, Atsuo Takanishi, “Development of a Ligature/Suture Training System which provides quantitative information of the learning process of trainees,” Proceedings of the International Conference on Robotics and Automation, pp. 2056-2061, 2007. [37] Nobuki Oshima, Jorge Solis, Hiroyuki Ishii, Kazuyuki Hatake, Atsuo Takanishi, “Acquisition of Quantitative Data for the Detailed Analysis of the Suture/Ligature Tasks with the WKS-2R,” Proceedings of the International Special Topic Conference on Information Technology in Biomedicine, pp. 210-213, 2007. [38] Nobuki Oshima, Jorge Solis, Hiroyuki Ishii, Noriyuki Matsuoka, Kazuyuki Hatake, Atsuo Takanishi: Integration of an evaluation function into the suture/ligature training system WKS-2R,” Proceedings of the International Conference on Robotics and Automation, pp. 1045-1050, 2008. 321 盧 [39] 博士論文 Solis, J., Oshima, N., Ishii, H., Matsuoka, N., Hatake, K., Takanishi, A., “Development of a Sensor System towards the Acquisition of Quantitative Information of the Training Progress of Surgical Skills,” Proceedings of the IEEE/RSJ International conference on Biomedical Robotics and Biomechatronics, pp. 340-345, 2008. [40] Jorge Solis, Nobuki Oshima, Hiroyuki Ishii, Noriyuki Matsuoka, Kazuyuki Hatake and Atsuo Takanishi,” Towards understanding the suture/ligature skills during the training process using WKS-2RII”, International Journal of computer assisted radiology and surgery, vol(3), no.3-4, pp. 231-239. [41] Noh, Y., Nagahiro, K., Ogura Y., Solis, J., Hatake, K., Takanishi, A.,” Design of Airway Management Training System,” Proceedings of the International Special Topic Conference on Information Technology Applications in Biomedicine, IO119, 2006. [42] Noh, Y., Nagahiro, K., Ogura Y., Ishii, H., Solis, J., Hatake, K., Takanishi, A.,” Development of Airway Management Training System which embeds array of sensors on a conventional mannequin,” IEEE/RSJ International Conference on Intelligent Robots and Systems, pp. 1296–1301 [43] Noh, Y., Segawa, M., Shimomura, A., Ishii, H., Solis, J., Hatake, K., Takanishi, A.,” Reproducing Difficulties of Airway Management on Patients with Restricted Opening Mouth using the WKA-1,” Proceedings of the International Special Topic Conference on Information Technology Applications in Biomedicine, pp. 115–118, 2007. [44] Noh, Y., Segawa, M., Shimomura, A., Ishii, H., Solis, J., Hatake, K., Takanishi, A.,” Determination of Effective Evaluation Parameters on the Airway Training System 322 Referencem WKA-1R,” Proceedings of the International Conference of the International Society for Gerontechnology, vol. 7, no.2, pp. 174, 2008. [45] Noh, Y., Segawa, M., Ishii, H., Solis, J., Hatake, K., Takanishi, A.,” Improvements on the sensor system on the WKA-1R to identify the evaluation parameters of the airway management,” Proceedings of Computer Assited Radiology and Surgery 22nd International Cogress and Exhibition, pp. S209-210, 2008. [46] Noh, Y., Segawa, M., Shimomura, A., Ishii, H., Solis, J., Hatake, K., Takanishi, A.,” Development of the Evaluation System for the Airway Management Training System WKA-1R,” Proceedings of the IEEE/RSJ International Conference on Biomedical and Biomechatronics, pp. 574-579, 2008. [47] Noh, Y., Segawa, M., Shimomura, A., Ishii, H., Solis, J., Hatake, K., Takanishi, A.,” WKA-1R Robot Assisted Quantitative Assessment of Airway Management,” International Journal of Computer Assisted Radiology and Surgery, vol. 3, no. 6, 543-550, 2008. [48] Noh, Y., Segawa, M., Shimomura, A., Ishii, H., Solis, J., Hatake, K., Takanishi, A.,” Development of the Airway Management Training System WKA-2 which can reproduce the Cases of Difficult Airway,” Proceedings of IEEE International Conference on Robotics and Automation, pp. 3833–3838, 2009. [49] Noh, Y., Sato, K., Shimomura, A., Segawa, M., Ishii, H., Solis, J., Hatake, K., Takanishi, A.,” Mechanism Design Improvements of the Airway Management Training System WKA-2”, Proceedings of the 17th CISM-IFToMM Symposium on Robot Design, Dynamics and Control, pp.103-110, 2008. [50] Noh, Y., Shimomura, A., Segawa, M., Ishii, H., Solis, J., Hatake, K., Takanishi, A.,” Development of Tension/Compression Detection Sensor System Designed to Acqure 323 盧 博士論文 uantitative Force Information while Training the Airway management,” Proceedings of IEEE/ASME International Conference on Advanced Intelligent Mechatronics, pp.1264 – 1269, 2009. [51] Noh, Y., Sato, K., Shimomura, A., Segawa, M., Ishii, H., Solis, J., Hatake, K., Takanishi, A.,” Mechanism Design Improvements of the Airway Management Training System WKA-3,” Proceedings of 18th CISM-IFToMM Symposium on Robot Design, Dynamics and Control, pp.183-190, 2010. [52] Noh, Y., Shimomura, A., Sato, K., Segawa, M., Ishii, H., Solis, J., Hatake, K., Takanishi, A.,” Development of Patient Scenario Generation which can Reproduce Characteristics of the Patient for Simulating Real-World Conditions of Task for Airway Management Training System WKA-3,” Proceedings of IEEE/RSJ International Conference on Intelligent Robots and Systems, pp.331-336, 2010. [53] Noh, Y., Shimomura, A., Sato, K., Segawa, M., Ishii, H., Solis, J., Hatake, K., Takanishi, A.,” Development of the Airway Management Training System WKA-3: Integration of Evaluation Module to Provide Assessment of Clinical Competence and Feedback Module to Reproduce Different Cases of Airway Difficulties,” Proceedings of IEEE/RSJ International Conference on Intelligent Robots and Systems, pp.337-342, 2010. [54] Noh, Y., Ebihara, K., Shoji, S., Segawa, M., Ishii, H., Solis, J., Hatake, K., Takanishi, A.,” Development of the Airway Management Training System WKA-4: for Improving Reproduction of High Fidelity of Real Patient and Improving Tongue Mechanism and Mandible Mechanism,” Proceedings of IEEE International Conference on Robotics and Automation, pp. 2028-2033, 2011. 324 Referencem [55] Holm-Knudsen RJ, Rasmussen LS, “Paediatric airway management: basic aspects,” Journal of Acta Anaesthesiol Scand., vol. 53, no.1, pp.1-9, Jan. 2009. [56] P. P. Bredmose, J.-K. Heltne,” Pre-hospital airway management guidelines: we need more,” Journal of Acta Anaesthesiol Scand., vol. 54, no.1, pp. 122–123, Jan. 2010. [57] Charles D Deakin, Tom Clarke, Jerry Nolan, David A Zideman, Carl Gwinnutt, Fionna Moore, Michael Ward, Carl Keeble, Wim Blancke,”Crtical reassessment of ambulance service airway management in prehospital care: Joint Royal Colleges Ambulance Liaison Committee Airway Working Group, June 2008”, Emergency Medicine Journal, vol. 27, no. 4, pp. 226-233, 2010. [58] Granholm T, Farmer DL,” The surgical airway,” Journal of Respiratory Care Clinics of North America, vol 7, no. 1, pp. 13-23, Mar. 2001. [59] Dr. Divatia J. V., Dr. Bhowmick K., “Complications of endotracheal intubation and other airway management procedures,” Indian journal of anaesthesia, vol. 49, no. 4, pp. 308-318, 2007. [60] Loh KS, Irish JC., “Traumatic complications of intubation and other airway management procedures,” Journal of Respiratory Care Clinics of North America, vol 20. no.2, pp. 953-969, 2002. [61] Domino KB, Postner KL, Caplan RA, Cheney FW, “Airway injury during anesthesia,” Journal of Anesthesiology, vol 91, no. 3, pp. 1703-1711, 1999. [62] Seitz PA, Gravenstein N., “Endobronchial rupture from endotracheal reintubation with an endotracheal tube,” The Journal of Clinical Anesthesia, vol. 1, no. 9, pp. 214, 1989. 325 盧 [63] 博士論文 Wagner DL, Gammage GW, Wong ML., “Tracheal rupture following insertion of a disposable double-lumen tube,” Journal of Anesthesiology, vol. 63, no. 12, pp. 698, 1985. [64] Kapadia FN, Bajan KB, Raje KV, “Airway accidents in intubated ICU patients: An epidemiological study,” Journal of Critical Care Medicine, vol. 28, no. 3, pp. 659664, 2000. [65] Sunanda Gupta, Rajesh Sharma KR, Dimpel Jain, “Airway assessment: predictors of difficult airway,” Indian Journal of Anaesthesia, vol 49, no. 4, pp. 257-262, 2005. [66] Benumof JL., Definition and incidence of the difficult airway: Principles and practice, 3rd Edition, St Louis Mosby, pp. 121-125, 1996:. [67] Robert C. Luten, Robert E. Schneider, Manual of Emergency airway management 2nd Editon, Lippincott William and Wilkins, 2005. [68] Rade B. Vukmir, Airway Management in the critically ill, 2nd Edition, Parthenon publishing, 2005. [69] Nishikawa, K, Young-Kwang Park, Aizuddin. M, Yoshinaga.K, Ogura K, Umezu M, Takanishi A,” Development of Carbon Microcoils (CMC) Sensor System with High Sensitivity for Effective Acquisition of Tactile Information,” Procceedings of the International Conference on Intelligent Robots and Systems, pp. 110-115, 2005. [70] Yoshiharu T., Naoya, A., Hiroyuki, S., “A study on tactile resolution of human skin,” Procceedings of the SICE Annual Conference, pp.3137-3139, 2002 [71] J Rubens, “Testing Airway Management Skills: Interactive Video Courseware vs ACLS Instructor,” Journal of Respiratory Care, vol. 36, no. 8, pp. 849-856, Aug 1991. [72] MedED Inc., [Online]. Portal https://www.mededportal.org/publication/631 326 Referencem [73] M. Polansky, “Airway Management: The Basics of Endotracheal Intubation,” Internet Journal of Academic Physician Assistants, vol. 1, no. 1, pp.210-218, 1997. [74] Ron M. Walls Michael F. Murphy, Manual of Emergency Airway Management, 3rd Edition, Wolters Kluwer Lippincott Williams and Wilkins, 2009. [75] Jay P. Goldsmith,Edward H. Karotkin, Assisted ventilation of the neonate, 5th Edition, SAUNDERS, 2011. [76] J Rubens, “Testing Airway Management Skills: Interactive Video Courseware vs ACLS Instructor,” Journal of Respiratory Care, vol. 36, no. 8, pp. 849-856, Aug. 1991. [77] American Heart Association, Instructor’s manual for advanced cardiac life support, 2nd Edition, Dallas Tx: AHA. 1987. [78] Aoyama, K., Tracheal Intubation Visual Manual of Clinical Basic Techniques, 1st Edition, Japan: Yodosya, pp.14-15, 2005. [79] Martin, J.L, Bucx, M.J.L., van de Vegt, M.H, Snijders C.J., Stijnen, T.,Wesselink, P., “Transverse forces exerted on the maxillary incisors during laryngoscopy,” Canadian Journal of Anaesthesia, vol. 43, no. 7, pp. 665-671, 1996. [80] P. Sengupta, D.I. Sessler, “Endotracheal tube cuff pressure in three hospitals, and the volume required to produce an appropriate cuff pressure,” Jounal of BMC Anesthesiology, vol. 23, no.4, pp.345-340, 2004. [81] Balakrishnama, S., Ganapathiraju, A., “Linear Discriminant Analysis-A Brief Tutorial,” Institute for Signal and Information Processing, Dep. of Electrical and Computer Engineering, Mississippi State University, 2006. [82] Ferdinand P. Beer, E. Russell, Jr. Johnston, Mechanics of Materials, 5th Edition, McGraw-Hill Science/Engineering/Math, 2000. 327 盧 [83] 博士論文 Ishihara T, Hasegawa S, AI M., Mandibular Movement and Articulators (in Japanese), Tokyo, Japan,. HYORON, p 103, 1975. [84] Edgar N. Starcke, “The History of Articulators: Scribing Articulators: Those with Functionally Generated Custom Guide Controls Part I,” Journal of Prosthodontics, vol 13, no. 2, pp 118-128, 2004. [85] Joseph Brimacombe, Christian Keller, Karl H. Kunzel Othmar Gaber, Michael Boehler, and Fredrich Puhringer, “Cervical Spine Motion During Airway Management: A Cinefluoroscopic Study of the Posteriorly Destabilized Third Cervical Vertebrae in Human Cadavers,” Journal of Anesthesia and Analgesia, vol. 91, no.5, pp. 1274 -1278, 2000. [86] Miwako Honma, “Relations between the bolus size and hyoid movement seen during natural ingestive behavious in humans,” Japan Nigata dental journal, vol. 36 no. 6, pp. 97, 2001. [87] 坂東永一, 三谷英夫, 上村修三郎ほか編, “顎機能障害 新しい診断システムと治 療指針,” 医歯薬出版株式会社, pp. 140-141, 1978. [88] Hiroyuki Ishii, Hiroki Koga, Yuichi Obokawa, Jorge Solis, Atsuo Takanishi and Akitoshi Katsumata, “Path generator control system and virtual compliance calculator for maxillofacial massage robots,” International Journal of Computer Assisted Radiology Surgery, vol. 5, no. 1, pp. 77-84. 2009. [89] LeGrand SA, Hindman BJ, Dexter F, Weeks JB, Todd MM, “Craniocervical notion during direct laryngoscopy and orotracheal intubation with the Macintosh and Miller blades: an in vivo cinefluoroscopic study,” Journal of Anesthesiology, vol.107, no.6, pp. 884-91, 2007. 328 Referencem [90] Bruce N. Epker, Timothy Turvey, and Leward C. Fish, “Indications forsimultaneous mobilization of the maxilla and mandible for thecorrection of dentofacial deformities,” Journal of Oral Surgery, Oral Medicine, Oral Pathology, vol.54, no. 4, pp. 369-381, 1982. [91] “Practice Guidelines for Management of the Difficult Airway – An Updated Report by the American Society of Anesthesiologists Task Force on Management of the Difficult Airway - SPECIAL ARTICLE,” Journal of Anesthesiology, vol. 98, no.5, pp. 1269–1277, 2003. [92] Edward T. Crosby, “Airway Management in Adults after Cervical Spine Trauma,” journal of Anesthesiology, vol. 104, no. 34, pp. 1293–1318, 2006. [93] Michael A. Seropian, “ General Concepts in Full Scale Simulation:Getting Started,” Journal of Anesthesia and Analgesia, vol. 97, no. 6, pp. 1695–1705, 2003. [94] J. Haase, E. Boisen, “Neurosurgical training: more hours needed or a new learning culture?,” Journal of Surgical Neurology, vol 72, no. 1, pp. 89-95, 2004 [95] Kiat, T., Mei, T., & Nagammal, S., “A review of learners’ experience with simulation based training in nursing,” Singapore Nursing Journal, vol. 34, no. 4, pp. 37-43, 2007. [96] Turkstra TP, Pelz DM, Shaikh AA, Craen RA., “Cervical spine motion: a fluoroscopic comparison of Shikani Optical Stylet vs Macintosh laryngoscope,” Canadian Journal of Anesthesia, vol. 54, no. 6, pp. 441-447, Jun 2007. [97] Al-alami AA, Zestos MM, Baraka AS.,”Pediatric laryngospasm: prevention and treatment,” Journal of Curr Opin Anaesthesiol, vol 22, no. 3, pp. 388-395, Jun. 2009. 329 盧 [98] 博士論文 Greenland KB.,”The sniffing and extension-extension position: the need to develop the clinical relevance,” Journal of Anaesthesia, vol. 63, no. 9, pp. 1013-1014, Sep. 2008. [99] Al-alami AA, Zestos MM, Baraka AS.,”Pediatric laryngospasm:prevention and treatment,” Journal of Curr Opin Anaesthesiol, vol. 22, no. 3, pp. 388-395, Jul. 2009. [100] Solis, J., Obokawa, Y., Ishii, H., Koga, H., Takanishi, A., Katsumata, A., “Development of Oral Rehabilitation Robot WAO-1R Designed to Provide Various Massage Techniques,” Proceedings of the IEEE 11th International Conference on Rehabilitation Robotic, pp.457–462, 2009. [101] Bruce N. Epker, Timothy Turvey, and Leward C. Fish,”Indications for simultaneous mobilization of the maxilla and mandible for the correction of dentofacial deformities,” Journal of Oral Surgery, Oral Medicine, Oral Pathology, vol. 54, no. 4, pp. 369-381, 1982. [102] Edward T. Crosby, “Airway Management in Adults after Cervical Spine Trauma,” Journal of Anesthesiology, vol 104, no. 45, pp. 1293-1318, 2006 [103] James W Youdas, Tom R Garrett, Vera J Suman, Connie L Bogard, Horace O Hallman and James R Carey, ”Normal Range of Motion of the Cervical Spine: An Initial Goniometric Study,” Journal of Physical Therapy, vol.72 no.l l, pp. 770-780, 1992. [104] Ichiro Takenaka, Kazuyoshi Aoyama, Tamao Iwagaki, Hiroshi Ishimura, Tatsuo Kadoya, “The sniffing position provides greater occipitoatlanto-axial angulation than simple head extension: a radiological study,” Canadian Journal of Anesthesia, vol 54, no. 2, pp 129–133, 2007. 330 Referencem [105] Minna Silvennoinen, Liisa Kuparinen, Finland, “Usability Challenges in Surgical Simulator Training”, Proceedings of the 31st International Conference on Information Technology Interfaces, pp. 455-460, 2009. [106] Laks Raghupathi, Laurent Grisoni, Franc¸ois Faure, Damien Marchal, Marie-Paule Cani, and Christophe Chaillou, “An Intestinal Surgery Simulator: RealTimeCollision Processing and Visualization” IEEE International Journal: Transactions on Visualization and Computer Graphics, vol 10, no. 6, pp.708-715, 2004. [107] Hideaki Takanobu, Akito Omata, Fumihiko Takahashi, Keishi Yokota, Kenji Suzuki, Hirofumi Miura, Mutsumi Madokoro, Yoshikazu Miyazaki, Koutarou Maki, “Dental Patient Robot as a Mechanical Human Simulator,” Proceedings of International Conference on Mechatronics, pp 1-6, 2007. [108] Brandon S. Spencer, “Incorporating the Sense of Smell Into Patientand Haptic Surgical Simulators,” IEEE International Journal: Transaction on Information Technology in Biomedicine, vol. 10, no. 1, pp.168-173, Jan. 2006. [109] Yongho Hwang, Samsun Lampotang, Nikolaus Gravenstein, Isaac Luria‡ Benjamin Lok,” Integrating Conversational Virtual Humans and Mannequin Patient Simulators to Present Mixed Reality Clinical Training Experiences”, Proceedings of IEEE International Symposium on Mixed and Augmented Reality and Technology,” pp. 197-198, 2009. [110] S. Ikeda, F. Arai, T. Fukuda, M. Negoro and K. Irie, I. Takahashi, “Patient-Specific Neurovascular Simulator for Evaluating the Performance of Medical Robots and Instrumens” Proceedings of IEEE International Conference on Robotics and Automation, pp. 625-630, 2006. 331 盧 [111] 博士論文 Yoshiro Kitagawa, Tomohito Ishikura, Wei Song, Yasushi Mae, Mamoru Minami and Kanji Tanaka, “Human-like Patient Robot with Chaotic Emotion for Injection Training”, Proceedings of ICROS-SICE International Joint Conference, pp. 46354640, 2009. [112] Yuta Nakano and Tomoharu Nagao, “Automatic Construction of Moving Object Segmentation from Video Image using 3D-ACTIT,” Proceedings of IEEE International Conference, pp. 1153-1158, 2007. [113] Xiaojing Zhou and Zhengxu Zhao, “Construction of 3D Virtual Humans from 2D Images,” Proceedings of IEEE International Conference on Networking, Sensing and Control, pp. 719 – 724, 2008. [114] Gamage, P., Xie, S.Q., Delmas, P., Xu, P., “3D Reconstruction of Patient Specific Bone Models from 2D Radiographs for Image Guided Orthopedic Surgery,” Proceedings of International Conference on Digital Image Computing: Techniques and Applications, pp. 212-216, 2009. [115] Graf, H., Sang Min Yoon, Malerczyk, C., “REAL-TIME 3D RECONSTRUCTION AND POSE ESTIMATION FOR HUMAN MOTION ANALYSIS,” Proceedings of IEEE 17th International Conference on Image Processing, pp. 3981-3984, 2009. [116] Sehwun Kim, Etzm-Young Chun,Chung-Hyun Ahit and Woontuck Woo, “Imagebased Panoramic 3D Virtual Environment Using Rotating Two Multi-view Cameras,” Proceedings of International Conference on Image Processing, pp. 917920, 2008. [117] Hamza-Lup, F.G.; Goeser, P.T.; Johnson, W.; Thompson, T.; Railean, E.; Popovici, D.M.; Hamza-Lup, G., “Interactive 3D Web-Based Environments for Online 332 Referencem Learning: Case Studies, Technologies and Challenges,” Proceedings of International Conference on Digital Object Identifier, pp. 13-18, 2009. [118] Maria L. Pinto, Jose M. Sabater, Jorge Sofrony, F. Javier Badesa, Juan Rodriguez, Nicolas Garcia, “Haptic Simulator for training of Total Knee Replacement,” Proceedings of International Conference on Biomedical Robotics and Biomechatronics, pp. 221 – 226, 2008. [119] Zhiyong Yuan, Qian Yin, Jun Hu, Shikun Feng and Dengyi Zhang, “Study on VRBased Medical Image Deformation for Surgical Training System,” Proceedings of the 4th International Conference, pp. 124 – 127, 2010. [120] Padilla, M.A., Teodoro, S., Lira, E.; Soriano, D., Altamirano, F., Arambula, F., “Virtual reality simulator of transurethral resection of the prostate,” International Conference on Health Care Exchanges, pp. 116-119, 2009. [121] Chang-qing Yu, He-hua Ju, Yang Gao, “3D virtual reality simulator for planetary rover operation and testing,” Proceedings of International Conference on Virtual Environments, Human-Computer Interfaces and Measurements Systems, pp. 101-106, 2009. [122] Chen Xiaojun, Lin Yanping, Wang Chengtao, Wu Yiqun, Wang Xudong, Shen Guofang, “An Integrated Surgical Planning and Virtual Training System using a Force Feedback Haptic Device for Dental Implant Surgery,” Proceedings of International Conference on Audio Language and Image Processing, pp. 1257 – 1261, 2010. [123] Wikipedia Inc., [Online]. Availiable: http://en.wikipedia.org/wiki/Airway_management 333 盧 [124] 博士論文 Z. Lin, M. Zecca, S. Sessa, L. Bartolomeo, H. Ishii, K. Itoh, and A. Takanishi, “Development of an Ultra-miniaturized Inertial Measurement Unit WB-3 for Human Body Motion Tracking,” Proceedings of IEEE/SICE International Conference, pp. 414-419, 2010. [125] A.J. Thexton and A.W. Crompton, “Control of swallowing, in Scientific Basis of Eating,” Ed. R.W.A. Linden, Karger, Basel, pp. 168-222, 1999. [126] Smithard DG, Smeeton NC, Wolfe CD., “Long-term outcome after stroke: does dysphagia matter?,” Age Ageing vol. 36, no. 1, pp. 90-94, 2008. [127] Brady A., “Managing the patient with dysphagia,” Journal of Home Healthc Nurse vol. 26, no. 1, pp. 41–6, 2002. [128] Logemann, Jeri A., “Evaluation and treatment of swallowing disorders,” Austin, Tex: Pro-Ed., 1998. [129] Shinichi Matsuzaki, Hitoshi Yamashita, Katsuaki Endou, Takehiko Araki, Satoshi Ban, Katue Yoshida, Tamotsu Ishizuka, Sakae Maruta and Masatomo Mori, “Aspiration Pneumonia Resulting from a Peanut,” Kitakanto Medical Journal, vol. 59, no. 12, pp. 161-163, 2009. [130] Yukihiro Iida, Akitoshi Katsumata and Masami Fujishita, “Effect of head rotation on the pathway of a food bolus through the pharynx as evaluated by a videofluoroscopic swallow study,” Journal of Oral Radiology, vol 12, no. 6, pp. 124-128, 2009. [131] Palmer JB, Kuhlemeier KV, Tippett DC, Lynch C., “A protocol for the videofluorographic swallowing study,” Journal of Dysphagia, vol. 8, no.3, pp. 209214, 1993. 334 Referencem [132] Kuhlemeier KV, Yates P, Palmer JB., “Intra- and interrater variation in the evaluation of videofluorographic swallowing studies,” Journal of Dysphagia, vol. 13, no. 6, pp. 142-147, 1998. [133] Effrey B. Palmer, and Jennifer C. Drennan, “Evaluation and Treatment of Swallowing Impairments,” American Family Physician, 2004. [134] AMO Bakheit, “Management of Neurogenic Dysphagia,” Postgrad Medical Journal, Vol. 77, no. 6, pp. 694-699, 2001. [135] Iida Yukihiro, Katsumata Akitoshi, Fujishita Masami, “A Simulation System for Dynamic Videofluoroscopic Swallow Examination,” Journal of Dental Radiology, vol.44; no.3; pp. 152-160, 2004. [136] Kano M, Shimizu Y, Okayama K, Igari T, Kikuchi M, “A Morphometric Study of Age-Related Changes in Adult Human Epiglottis Using Quantitative Digital Analysis of Cartilage Calcification,” Journal of Cells Tissues Organs, vol. 180, no. 34, pp. 126-137, 2005. [137] Garon BR, Huang Z, Hommeyer M, Eckmann D, Stern GA, Ormiston C, “Epiglottic dysfunction: abnormal epiglottic movement patterns,” Journal of Dysphagia, vol. 17, no.1, pp. 57-68, 2002. 335 盧 博士論文 336 Research Achievements 種類別 題名 発表・発行掲載 誌名 発表・発行年月 連名者 1. 論文 Proceedings of 2011 IEEE International Conference on Robotics and Automation, pp. 4676-4681, 2011 2011 年 5 月 ノヨハン 瀬川正尚 佐藤圭 Wang Chunbao 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 勝又明敏 飯田幸弘 Proceedings of 2011 IEEE International Conference on Robotics and Automation, pp. 1726-1731, 2011 2011 年 5 月 ノヨハン 海老原一樹 瀬川正尚 佐藤圭 Wang Chunbao 石井裕之 ソリスホルヘ 高西淳夫 畠和幸 庄司聡 Development of the Airway Management Training System WKA3: Integration of Evaluation Module to Provide Assessment of Clinical Competence and Feedback Module to Reproduce Different Cases of Airway Difficulties Proceedings of 2010 IEEE/RSJ International Conference on Intelligent Robots and Systems, pp. 337-342, 2010 2010 年 10 月 ノヨハン 佐藤圭 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 ○ Development of Patient Scenario Generation which can Reproduce Characteristics of the Patient for Simulating Real-World Conditions of Task for Airway Management Training System WKA-3 Proceedings of 2010 IEEE/RSJ International Conference on Intelligent Robots and Systems, pp. 331-336, 2010 2010 年 10 月 ノヨハン 佐藤圭 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 Development of a Robot which can Simulate Swallowing of Food Boluses With Various Properties for the Study of Rehabilitation of Swallowing Disorders ○ Development of the Airway Management Training System WKA4 : Improved HighFidelity Reproduction of Real Patient Conditions and Improved Tongue and Mandible Mechanisms 337 博士論文 m 盧 種類別 題名 論文の続 Mechanism Design き Improvements of the Airway Management Training System WKA3 Development of Airway Management Training System WKA3 発表・発行掲載 誌名 Proceedings of 17th CISMIFToMM Symposium on Robot Design, Dynamics and Control, pp. 183-190, 2010 Proceedings of 2009 IEEE International Crossdisciplinary Symposium on Micro-Nano Systems, 2009 Development of Tension/Compression Detection Sensor System Designed to Acqure Quantitative Force Information while Training the Airway management Proceedings of 2009 IEEE/ASME International Conference on Advanced Intelligent Mechatronics, pp. 1264-1269, 2009 Development of the Proceedings of Airway Management 2009 IEEE Training System WKA- International 2 which can reproduce Conference on the Cases of Difficult Robotics and Airway Automation, pp. 3833-3838, 2009 ○ WKA-1R Robot Assisted Quantitative Assessment of Airway Management International Journal of Computer Assisted Radiology and Surgery, vol. 3, no. 6, pp. 543-550, 2008 338 発表・発行年月 連名者 2010 年 7 月 ノヨハン 佐藤圭 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 2009 年 11 月 ノヨハン 佐藤圭 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 2009 年 7 月 ノヨハン 佐藤圭 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 ノヨハン 佐藤圭 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 2009 年 5 月 2008 年 11 月 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 Research Achievements m 種類別 題名 論文の続 Development of the き Evaluation System for the Airway Management Training System WKA-1R 発表・発行掲載 誌名 発表・発行年月 連名者 Proceedings of IEEE/RSJ International Conference on Biomedical and Biomechatronics, pp. 574-579, 2008 2008 年 9 月 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 Improvements on the sensor system on the WKA-1R to identify the evaluation parameters of the airway management Proceedings of 2008 Computer Assited Radiology and Surgery 22nd International Cogress and Exhibition, pp. s209-s210 2008 年 6 月 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 Determination of Effective Evaluation Parameters on the Airway Training System WKA-1R Proceedings of 6th Conference of the International Society for Gerontechnology, 2008 2008 年 5 月 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 Reproducing Difficulties of Airway Management on Patients with Restricted Opening Mouth using the WKA-1 Proceedings of 6th International Special Topic Conference on Information Technology Applications in Biomedicine, pp. 115-118 2007 年 11 月 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 Development of Airway Management Training System which embeds array of sensors on a conventional mannequin Proceedings of 2007 IEEE/RSJ International Conference on Intelligent Robots and Systems, pp. 1296-1301, 2007 2007 年 10 月 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 339 盧 種類別 博士論文 m 題名 論文の続 Design of Airway き Management Training System 発表・発行掲載 誌名 Proceedings of 5th International Special Topic Conference on Information Technology Applications in Biomedicine, pp. 102-107, 2006 発表・発行年 月 連名者 2006 年 10 月 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 気道管理教育訓練シス テム WKA-4 の開発 -動作パターンの生成 アルゴリズムと筋肉の 再現可能なシステム制 御- 第 11 回計測自動 2010 年 12 月 制御学会システム インテグレーショ ン部分講演会予稿 集 ノヨハン 海老原一樹 佐藤圭 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 嚥下障害を再現した患 者ロボット WKA-2 の 開発-物性特性が異な る食べ物により嚥下障 害患者への影響- 第 11 回計測自動 2010 年 12 月 制御学会システム インテグレーショ ン部分講演会予稿 集 ノヨハン 海老原一樹 佐藤圭 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 臨場感を再現した気管 挿管訓練システムの開 発 第 40 回日本救急 医学学会 ノヨハン 海老原一樹 佐藤圭 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 気道管理教育訓練シス テムWKA-4 の開発 -気道管理における患 者状態の再現機能を有 するハードウェアの設 計・製作- 第 28 回日本ロボ 2010 年 9 月 ット学会学術講演 会予稿集 2. 講演 340 2010 年 10 月 海老原一樹 瀬川正尚 ノヨハン 佐藤圭 石井裕之 高西淳夫 庄司 聡 畠和幸 Research Achievements m 種類別 題名 講演の続 訓練者の定量的な手技 き 評価と患者の臨場感の 再現ができる気管挿管 訓練用頭部モデル WKA-3 の開発 発表・発行掲載 誌名 42 回日本医学教 育学会 発表・発行年 月 連名者 2010 年 7 月 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 気管挿管訓練システム の力センサの開発-手 技評価用センサと力制 御用センサの開発- 27 回日本ロボッ 2009 年 9 月 ト学会学術講演会 予稿集 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 気管挿管訓練システム WKA-3 の開発-患者の 状態が再現できるシナ リオ再現アルゴリズム の開発- 第 27 回日本ロボ 2009 年 9 月 ット学会学術講演 会予稿集 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 気管挿管訓練システム WKA-3 の開発-症例再 現機能と手技計測機能 を有するハードウェア の設計•製作- 第 27 回日本ロボ 2009 年 9 月 ット学会学術講演 会予稿集 佐藤圭 下村章宏 ノヨハン 瀬川正尚 石井裕之 ソリスホルヘ 高西淳夫 畠和幸 ロボットによる嚥下時 口腔咽頭形態再現の可 能性 日本歯科放射線学 2009 年 9 月 会第 209 回関東 地方会・第 29 回 北日本地方会 第 17 回合同地方 会 勝又明敏 飯田幸弘 藤下昌己 ノヨハン 石井裕之 高西淳夫 341 盧 種類別 博士論文 m 題名 講演の続 症例·個体差が再現でき き る気管挿管手技訓練ロ ボットWKA-2 の開発 ―張力センサの開発と 仮想コンプライアンス 制御への応用― 発表・発行掲載 発表・発行年月 誌名 連名者 ロボティクス‧メ 2009 年 5 月 カトロニクス講演 会 2009 予稿集 ノヨハン 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 ワイヤ制御を用いてヒ トの症例個体差が再現 可能な気管挿管訓練用 頭部モデル WKA-2 の開 発 第 9 回計測自動制 2008 年 12 月 御学会システムイ ンテグレーション 部分講演会予稿集 瀬川正尚 ノヨハン 石井 裕之 SOLIS Jorge 高西 淳 畠 和幸 気管挿管訓練用頭部モ デル WKA-2 の開発 第 17 回日本コン 2008 年 12 月 ピュータ外科学会 大会講演会予稿集 瀬川 正尚 ノ ヨハン 石井 裕之 SOLIS Jorge 高西 淳夫 畠和幸 気管挿管手技訓練シス テムの開発 -咀嚼筋等 の顎口腔周りの筋を模 したワイヤにより, 個体差および開口障害 などの気管挿管困難症 が再現可能なシステム の製作- 第 19 回日本咀嚼 学会学術大会 2008 年 9 月 瀬川正尚 NOH Yohan 下村彰宏 石井裕之 SOLIS Jorge 畠和幸 高西淳夫 訓練者手技の評価が可 能な気管挿管手技訓練 システムの開発 第 28 回日本臨床 麻酔学会 2008 年 9 月 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 Development of Airway Management Training System WKA-1R which enables to evaluate operators’ task performance 第 38 回日本救急 医学学会 2008 年 9 月 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 342 Research Achievements m 種類別 題名 発表・発行掲載 発表・発行年月 誌名 連名者 気管挿管訓練手技評価 第 26 回日本ロボ 2008 年 9 月 システムの開発(第 3 ット学会学術講演 報)-気管挿管手技評価関 会 数の開発 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 気管挿管訓練用頭部モ 第 26 回日本ロボ 2008 年 9 月 デル WKA-2 の開発-気 ット学会学術講演 管挿管困難症と多様な 会 口腔形状の再現が可能 なハードウェアの設 計・製作- 瀬川正尚 ノヨハン 石井裕之 ソリスホルヘ 高西淳夫 畠和幸 2008 年 7 月 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 気管挿管訓練手技評価 第 25 回日本ロボ 2007 年 9 月 システムの開発(第 2 ット学会学術講演 報)-気管挿管訓練頭部モ 会 デルの製作 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 気管挿管手技訓練シス テムの開発-咀嚼障害 による開口障害を再現 し気管挿管の定量的な 情報が得られるシステ ムの製作 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 Development of Evaluation System for Airway Management Training System WKA-1R 40 回日本医学教 育学会講演会 第 18 回日本咀嚼 学会 343 2007 年 7 月 盧 種類別 博士論文 m 題名 講演の続 気管挿管手技の定量的 き 評価が可能なトレーニ ング用頭部モデルの開 発, 3. 招待 講演 発表・発行掲載 発表・発行年月 誌名 第 39 回日本医学 教育学会講演会 連名者 2007 年 7 月 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 気管挿管訓練手技評価 第 24 回日本ロボ 2006 年 9 月 システムの開発(第 1 ット学会学術講演 報)-全体構想とセンシン 会 グシステムの設計 ノヨハン 下村章宏 瀬川正尚 石井裕之 ソリスホルヘ 畠和幸 高西淳夫 気管挿管訓練システム の開発 第 6 回日本シミュ レーション学会 2009 年 10 月 ノヨハン Development of Airway Management training System WKA-3 TOULOUSE cedex 04, France 2010 年 7 月 ノヨハン 気管挿管訓練装置 特願 2006-239817 特開 2008-64824 2008 年 3 月 ノヨハン 長弘考司 瀬川正尚 石井裕之 ソリスホテル 高西淳夫 畠和幸 4. 特許 344 Research Achievements m 種類別 題名 特許の続 光学式力センサ き 発表・発行掲載 発表・発行年月 誌名 連名者 特願 2008-85233 特開 2009-236799 2009 年 10 月 ノヨハン 下村彰宏 瀬川正尚 石井裕之 ソリスホテル 高西淳夫 畠和幸 力センサ及びセンシン グシステム 特願 2009-54311 特開 2010-210294 2010 年 9 月 ノヨハン 石井裕之 ソリスホテル 高西淳夫 位置検出装置,そのプ ログラム,モニタリン グシステム,及び気管 挿管訓練装置 特願 2008-254328 特開 2010-85687 2010 年 4 月 ノヨハン 下村彰宏 瀬川正尚 石井裕之 ソリスホテル 高西淳夫 畠和幸 気管挿管訓練装置 WO/2009/113196 2009 年 9 月 ノヨハン 下村彰宏 瀬川正尚 石井裕之 ソリスホテル 高西淳夫 畠和幸 時間経過による患者の 状態変化が再現できる 気管挿管訓練用頭部モ デル WKA-3 の開発 日本コンピュータ 2010 年 3 月 外科学会 2009 年 度講演論文賞受賞 佐藤圭 ノヨハン 下村彰宏 瀬川正尚 石井裕之 ソリスホテル 高西淳夫 畠和幸 5. 受賞 345 盧 種類別 博士論文 m 題名 発表・発行掲 載誌名 発表・発行年月 連名者 受賞の続 き 気道管理教育訓練シ ステム WKA-4 の開 発 第 11 回計測自動 制御学会システ ムインテグレー ション部分講演 会優秀講演賞 346 2010 年 12 月 ノヨハン 海老原一樹 瀬川正尚 佐藤圭 石井裕之 高西淳夫 庄司聡 畠和幸 Research Achievements m Award Certificate 347 盧 博士論文 m 348 Research Achievements m 349 盧 博士論文 m 350
© Copyright 2024 ExpyDoc