CIFANI NOEMI Present position

CIFANI NOEMI
Present position
-From May 2014 to Aprli 2015. Department of Biology and Biotechnology C. Darwin,
Sapienza University (Rome-Italy): research grant.
Education
-October 2009-October 2012. Department of Biology and Biotechnology Charles Darwin, Sapienza
University (Rome-Italy): PhD in Cellular and Developmental Biology.
-June 2010: abilitazione all’esercizio della professione di biologo.
- 2009. Sapienza University (Rome-Italy), Faculty of Biology, Thesis: Evaluation of antimicrobial
activity of probiotic bacteria against Salmonella enterica subsp. enterica serovar typhimurium 1344.
Prof F. Ascenzioni, Dr C. Marianelli. 110/110 cum laude.
-October 2007-November 2009. Training at the Department of Food Safety and Veterinary Public
Health, Istituto Superiore di Sanità (Rome-Italy): identification and characterization of zoonotic
pathogens (Brucella, Salmonella, Mycobacterium) and analysis of their pathogenic mechanisms.
-June-October 2007. Training at the Institute of agro-environmental and forest biology, National
Research Council (CNR) (Italy): evaluation of the effect of cadmium on soil microbial
communities.
Professional Experience
-2013. Sapienza University (Rome-Italy): "Avvio alla Ricerca 2013" financing for the
project " Atherosclerosis and macrophage MMP".
-From April 2013 to March 2014. Department of Clinical and Molecular Medicine,
Sant'Andrea Hospital, Sapienza University (Rome-Italy): research grant.
-November 2012-February 2013. Istituto Pasteur Cenci Bolognetti Foundation: fellowship
for research.
Specific Foreign Countries experience
-May -October 2012. Training at the Department of Medicine, Royal College of Surgeons in
Ireland, Education and Research Centre, Beaumont Hospital (Dublin, Ireland): macrophage
mediated microbial killing with particular focus on the effect of metalloproteases.
-October 2008. Training at the Montepellier 2 University-Centre National De La Recherche
Scientifique–CNRS (France): identification and characterization of Brucella species by
molecular biology.
Participation to congress and workshops
-36th European Cystic Fibrosi Conference. Lisbon, Portugal, 12-15 june 2013.
-35th European Cystic Fibrosi Conference. Dublin, Ireland, 6-9 june 2012.
-XVII Congresso Italiano della Fibrosi Cistica, VII Congresso della Società Italiana per lo
studio della Fibrosi Cistica, Tirrenia, Pisa, 23-26 november 2011.
-34th European Cystic Fibrosi Conference. Hamburg, Germany, 8-11 june 2011.
-ICAR2010, Valladolid, Spain, 3-5 november 2010.
-IV workshop Nazionale di Epidemiologia Veterinaria “Epidemiologia: strumenti per
conoscere, agire e decidere in Sanità Pubblica Veterinaria”. Università degli Studi La Sapienza,
Roma, 11-12 dicembre 2008.
Posters and Presentations
-Cifani N, Ferri V, Pompili B, Fradiani P, Di Domenico EG, Del Porto P, Ascenzioni F. Phenotypic
analysis of Pseudomonas aeruginosa strains isolated from CF lungs. 30th SIMGBM Meeting 2013.
Ischia, 18-21 September 2013.
-Cifani N, Reeves EP, McElvaney NG, Pompili B, Del Porto P, Ascenzioni F. Role of macrophage
proteases in the killing of intracellular bacteria. 36th European Cystic Fibrosi Conference. Lisbon,
Portugal, 12-15 june 2013. (Oral presentation)
-Pompili B, Cifani N, Anile M, Venuta F, Ciminno G, Quattrucci S, Ascenzioni F, Del Porto P. ROS
contribute to P. aeruginosa killing by CF macrophages. XII FISV Congress, Rome, Italy, 24-27
September 2012.
-Pompili B, Cifani N, Anile M, Venuta F, Quattrucci S, Ascenzioni F, Del Porto P. Lung
macrophages from CF patients show a severely compromised bactericidal activity against P.
aeruginosa that is independent from intracellular ROS production. 35th European Cystic Fibrosi
Conference. Dublin, Ireland, 6-9 june 2012.
- Bevivino A, Pirone L, Pilkington R, Cifani N, Dalmastri C, Callaghan M, Ascenzioni F, McClean
S. Environmental Burkholderia cenocepacia strains can disrupt epithelial integrity in bronchial
epithelial cells in vitro and have a more profound effect on ZO-1 in CF cells. 35th European Cystic
Fibrosi Conference. Dublin, Ireland, 6-9 june 2012.
-Cifani N, Guarnieri S, Mariggiò MA, Spadaro F, Guglietta S, Anile M, Venuta F, Quattrucci S,
Ascenzioni F, Del Porto P. Attività battericida dei macrofagi polmonari FC diretta contro
Pseudomonas aeruginosa. XVII Congresso Italiano della Fibrosi Cistica, VII Congresso della
Società Italiana per lo studio della Fibrosi Cistica, Tirrenia, Pisa, 23-26 november 2011. (Oral
presentation)
-Cifani N, Guarnieri S, Di Domenico E, Mariggiò MA, Spadaro F, Guglietta S, Anile M, Venuta F,
Quattrucci S, Ascenzioni F, Del Porto P. Bactericidal activity of human CF Macrophages against
Pseudomonas aeruginosa. 34th European Cystic Fibrosi Conference. Hamburg, Germany, 8-11 june
2011. (Oral presentation)
-Marrapodi R, Cifani N, Quattrucci S, Del Porto P, Ascenzioni F.. Exploiting the antimicrobial
mechanisms of human macrophages against Pseudomonas aeruginosa. ECFS Basic Science
Conference "New Frontiers in Basic Science of Cystic Fibrosis". Tirrenia, Italy, 30 march - 2 april
2011.
-Cifani N, Armas F, Di Marco V, Aronica V, Mazzone P, Corneli S, Capucchio MT, Pasquali P,
Marianelli C. Assessment and genetic characterization of drug resistance in Mycobacterium bovis
strains from animals in Sicily. ICAR2010, Valladolid, Spain, 3-5 november 2010.
-Tarantino M, Martucciello A, Marianelli C, Cifani N, DE Carlo E, Schiavo L, Captano F, Pasquali
P. Detecnion of Coxiella brunetii in water buffalo dairy herds bulk tank milk. Med-Vet- Net 5th
Annual Scientific Meeting; El Escorial, Madrid, Spain, 3-6 june 2009.
-Maranelli C, Cifani N, Pasquali P. Evaluation of antimicrobial activity of probiotics agains
Salmonella enterica serovar Typhimurium 1344. Med-Vet-Net 5th Annual Scientific Meeting; El
Escorial, Madrid, Spain, 3-6 june 2009.
- Di Marco V, Marianelli C, Cifani N, Aronica V, Foasconaro M, Russo M, Amedeo S, Catalano D,
Guarda F, Capecchio MT. IL suino nero dei Nebrodi quale possibile serbatoio della tubercolosi
all’interno di un’area protetta (parco dei Nebrodi): esperienze personali in sei anni di
sorveglianza(2003-2008). Atti della SIPAS (Società Italiana di Patologia ed Allevamento dei suini),
XXXV Meeting Annuale, Modena, 12-13 marzo 2009.
- Marianelli C, Cifani N, Capecchio MT, Fiasconaro M, Russo M, Pasquali P, Di Marco V. Raro
caso di tubercolosi ovina generalizzata da Mycobacterium bovis. IV workshop Nazionale di
Epidemiologia Veterinaria “Epidemiologia: strumenti per conoscere, agire e decidere in Sanità
Pubblica Veterinaria”. Università degli Studi La Sapienza, Roma, 11-12 dicembre 2008.
-Marianelli C, Cifani N, Russo M, Aronica V, Pasquali P, Di Marco V. Preliminary assessment of
tuberculosis in free roaming Nero Siciliano pig populetion. Med-Vet-Net 4th Annual Scientific
Meeting; St Malo, France, 11-14 june 2008.
Publications
- Del Porto F, Cifani N, Proietta M, Taurino M. MMP-12 and macrophage activation in acute aortic
dissection. Accepted for publication in Cardiology.
- Proietta M, Tritapepe L, Cifani N, Ferri L, Taurino M, Del Porto F. MMP-12 as a new marker of
Stanford-A acute aortic dissection. Ann Med. 2014 Feb;46(1):44-8.
-Bordi F, Chronopoulou L, Palocci C, Bomboi F, Di Martino A, Cifani N, Pompili B, Ascenzioni F,
Sennato S. Chitosan–DNA complexes: Effect of molecular parameters on the efficiency of delivery.
Colloids and Surfaces A: Physicochem. Eng. Aspects. 2014. Article in press.
-Cifani N, Pompili B, Anile M, Patella M, Diso D, Venuta F, Cimino G, Quattrucci S, Di Domenico
EG, Ascenzioni F, Del Porto P. Reactive-oxygen-species-mediated P. aeruginosa killing is
functional in human cystic fibrosis macrophages. PLoS One. 2013 Aug 19;8(8):e71717.
- Di Domenico EG, Mattarocci S, Cimino-Reale G, Parisi P, Cifani N, D'Ambrosio E, Zakian VA,
Ascenzioni F. Tel1 and Rad51 are involved in the maintenance of telomeres with capping
deficiency. Nucleic Acids Res. 2013 Jul;41(13):6490-500.
-Bevivino A, Pirone L, Pilkington R, Cifani N, Dalmastri C, Callaghan M, Ascenzioni F, McClean
S. Interaction of environmental Burkholderia cenocepacia strains with cystic fibrosis and non-cystic
fibrosis bronchial epithelial cells in vitro. Microbiology. 2012 May;158(Pt 5):1325-33. Epub 2012
Feb 9.
-Di Marco V, Mazzone P, Capucchio MT, Boniotti MB, Aronica V, Russo M, Fiasconaro M, Cifani
N, Corneli S, Biasibetti E, Biagetti M, Pacciarini ML, Cagiola M, Pasquali P, Marianelli C.
Epidemiological significance of the domestic black pig (Sus scrofa) in maintenance of bovine
tuberculosis in Sicily. J Clin Microbiol. 2012 Apr;50(4):1209-18. Epub 2012 Feb 8.
-Del Porto P, Cifani N, Guarnieri S, Di Domenico EG, Mariggiò MA, Spadaro F, Guglietta S, Anile
M, Venuta F, Quattrucci S, Ascenzioni F. Dysfunctional CFTR alters the bactericidal activity of
human macrophages against Pseudomonas aeruginosa. PLoS One. 2011;6(5):e19970. Epub 2011
May 18.
-Marianelli C, Cifani N, Pasquali P. Evaluation of antimicrobial activity of probiotic bacteria
against Salmonella enterica subsp. enterica serovar typhimurium 1344 in a common medium under
different environmental conditions. Res Microbiol. 2010 Oct;161(8):673-80. Epub 2010 Jul 1.
-Marianelli C, Cifani N, Capucchio MT, Fiasconaro M, Russo M, La Mancusa F, Pasquali P, Di
Marco V. A case of generalized bovine tuberculosis in a sheep. J Vet Diagn Invest. 2010
May;22(3):445-8

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