From Molecular Pathogenesis to Targeted Therapy

SEMI-FINAL PROGRAM
From Molecular Pathogenesis to Targeted Therapy
OCTOBER 27-31, 2014
ROOM V3-26/30 LUMC BUILDING 3 (ONDERWIJSGEBOUW)
ORGANIZERS: PETER TEN DIJKE AND HANS VAN DAM
Monday, October 27, 2014 Moderator: Peter ten Dijke/ Hans van Dam
Signaling pathways
Peter ten Dijke (LUMC)
Introduction and general principles
Hans van Dam (LUMC)
Signaling integration: MAPK/AP1 and TGFb/Smad
Alfred Vertegaal (LUMC)
Post-translational modifications
Daniele Guardavaccaro (Hubrecht)
Ubiquitin ligases
Alexander Vahrmeijer (LUMC)
Image-guidance in cancer surgery
Tuesday, October 28, 2014 Moderator: Peter ten Dijke/Hans van Dam
Diabetes, ageing and bone-related diseases
Bruno Guigas (LUMC)
Insulin, AMPK, and type 2 diabetes
Fried Zwartkruis (UMCUtrecht)
Ras/GTPAse signaling metabolism (amino acid sensing)
Boudewijn Burgering (UMCUtrecht)
PKB, Forkhead transcription factors and longevity
Peter ten Dijke (LUMC)
BMPs and Wnt in high bone mass diseases
Neveen Hamdy (LUMC)
RANKL-signaling and pathogenesis of bone loss
Jan Hoeijmakers (ErasmusMC)
DNA damage and longevity
Wednesday, October 29, 2014 Moderator: Peter ten Dijke/ Hans van Dam
Growth control, stem cells and cancer
Jarno Drost (Hubrecht)
Wnt signalling, intestinal stem cells and cancer
Jan Paul Medema (AMC)
Cancer stem cells
Ricardo Fodde (ErasmusMC)
Personalized cancer medicine: the other side
Roderick Beijersbergen (NKI)
Genome wide identification of targets for anticancer drugs
Arnoud Sonnenberg (NKI)
Integrins
Suzanne Lens (UMCUtrecht)
Mitotis, Aneuploidy and Cancer
Thursday, October 30, 2014 Moderator: Peter ten Dijke/Hans van Dam
Personalized, targeted therapy and imaging
Remco van Doorn (LUMC)
Targeted therapy in melanoma
Ferry Ossendorp (LUMC)
Immunetherapy
? Onno Kranenburg (UMCUtrecht) Determinants of metastasis in colon cancer
John Martens (ErasmusMC)
Circulating tumor cells and metastatic (breast) cancer
Fijs van Leeuwen (LUMC)
Targeted imaging agents for molecular imaging applications
Friday, October 31, 2014
Moderator: Peter ten Dijke/Hans van Dam
Presentations by PhD students

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