a (ng/mg protein) MMP-9 b 1800 ** 1400 1200 ** ** 1200 ** ** 1000 1000 800 800 600 600 ** 400 400 200 200 0 plasma 0.7 ±1.7 (ng/ml) 0 granulo lymphocytes platelets cytes monocytes 212.0 ±314.9 46.6 ±62.2 11.9 ±28.2 plasma granulo cytes 0.9 ±1.2 (ng/ml) d lymphocytes platelets monocytes 7.0 ±12.0 16.1 ±37.4 237.8 ±265.0 1500 5000 4000 * ** ** ** ** 1000 1500 750 1000 ** ** ** 500 0 * ** ** ** 250 0 Kawasaki disease Purulent Febrile Afebrile Group Group Group meningitis controls controls 1 2 3 54.0 ±26.1 Kawasaki disease Purulent Febrile Afebrile GroupGroup Group meningitis controls controls 1 2 3 740.0 389.6 411.1 386.0 299.8 140.8 ±429.2±467.7±336.6 ±275.3 ±195.2 ±61.4 MMP-9/TIMP-1 8 7 ** 6 5 4 * 3 ** * ** * ** * 2 1 0 ** 500 ** ** ** 212.1 139.7 130.4 1964.7 488.4 ±1761.1 ±260.1 ±150.9 ±97.3 ±81.8 * 1250 2000 e **: p<0.01 *: p<0.05 1400 1600 c TIMP-1 (ng/mg protein) Kawasaki disease Group 1 Group 2 Group 3 2.5 ±1.5 2.5 ±2.2 0.5 ±0.7 Purulent meningitis Febrile controls Afebrile controls 0.6 ±0.7 0.4 ±0.3 0.4 ±0.4
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