Institute of Pathology
In cooperation with:
»» Leibniz Institute for Age Research
(Fritz Lipmann Institute)
IZKF Graduate Program for Experimental Medicine
»» Leibniz Institute for Natural Products and
Infection Biology Jena (Hans-Knöll-Institute)
7th POSTGRADUATE
SYMPOSIUM
ON CANCER RESEARCH
Saturday, April 25, 2015
Altes Schloss Dornburg (Kaisersaal)
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ORGANIZATION
Institute of Pathology, Jena University Hospital
in collaboration with
» Interdisciplinary Center for Clinical Research (IZKF) Graduate
Program for Experimental Medicine, University Hospital Jena
» UniversitätsTumorCentrum (UTC) Jena
» Leibniz Institute for Age Research (Fritz Lipmann Institute)
» Leibniz Institute for Natural Products and Infection Biology Jena (Hans-Knöll-Institute)
» Jena School of Molecular Medicine
» Jena Graduate Academy
Prof. Dr. Iver Petersen, Prof. Dr. Alexander Berndt
Phone: +49-(3641)-934002
Email:[email protected]
SCIENTIFIC COMMITEE
Backsch, Claudia
Häfner, Norman
Baniahmad, Aria
Heller, Regine
Beck, James Friderich
Hilger, Ingrid
Berndt, Alexander
Hochhaus, Andreas
Berndt, Angela
Huber, Otmar
Böhmer, Frank-Dietmar
Liehr, Thomas
Chen, Yuan
Markert, Udo
Clement, Joachim H.
Melle, Christian
Dürst, Matthias
Petersen, Iver
Englert, Christoph
Popp, Jürgen
Ewald, Christian
Schulz, Stefan
Franz, Marcus
Stallmach, Andreas
Friedrich, Karlheinz
Wang, Zhao-Qi
Guntinas-Lichius, Orlando
Weigand, Wolfgang
Hansel, Alfred
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LOCATION
Kaisersaal, Altes Schloss Dornburg
TRAVELLING
By train:
Take the regional train from Jena-Paradies to Dornburg (Saale).
See following link to check the schedule: http://vmt.hafas.de
By car (from Jena):
Caution: the street lead to Altes Schloss Dornburg is now under construction.
Please take the alternate detour route. Give (Jena to:50.9632459,11.5966081
to:51.0022176,11.6193937 to:Dornburg/Saale) to your navigation or Google Map
(Schloßplatz, 07778 Camburg, Germany)
Das Symposium ist als ärztliche Fortbildungsveranstaltung im Rahmen des Fortbildungszertifikats der Landesärztekammer Thüringen anerkannt (Kategorie A, Punkte 9).
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THIS SYMPOSIUM IS
SUPPORTED BY:
Boehringer Ingelheim Pharma GmbH & Co. KG . . . . . . . . . . . . . . . . . . . (with 500€)
Carl Zeiss Jena GmbH . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (with 750€)
Dako Deutschland GmbH . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (with 500€)
Lilly Deutschland GmbH . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (with 750€)
Merck Serono GmbH . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (with 500€)
Novartis Pharma GmbH . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (with 1250€)
QIAGEN GmbH . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (with symposium materials)
Roche Pharma AG . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (with 1000€)
Zytomed systems GmbH . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (with 500€)
ZytoVision GmbH . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (with 500€)
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PROGRAM
8:00 Registration
9:00
Welcome address
Prof. Dr. O. Guntinas-Lichius, Vice Dean of Study Affairs of the Medical
Faculty of the Friedrich Schiller University of Jena
9:10
JIP Cancer Graduation Award – Introduction
Prof. Dr. Andreas Hochhaus, Director of the Department for Internal
Medicine II, Jena University Hospital; Vice-dean for Research of Medical
Faculty of FSU; Director of the UniversitätsTumorCentrum Jena
Lecture of the laureate
9:30
Keynote lecture
Prof. W.W. Franke (Helmholtz Group for Cell Biology, German Cancer Research
Center DKFZ): “Molecular Diagnostics: Immunocytochemistry using cytoskeletal
and junctional cell type markers”
10:30
Coffee break
11:00
ORAL PRESENTATIONS
SESSION 1: TUMOR CELL BIOLOGY
Chairs: Frank Böhmer, Daniel Kritsch
1Inhibitor of Growth 2 Inhibits Androgen Receptor Signaling in Prostate
Cancer Cells
Pungsrinont, Thanakorn; Institute of Human Genetics, Jena University
Hospital
2Androgen-dependent regulation of long non-coding RNAs in prostate
cancer
Maiwald, Caroline; Institute of Human Genetics, Jena University
Hospital
3Androgen receptor-dependent regulation of hTERT
Kacal, Merve; Institute of Human Genetics, Jena University Hospital
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4AR-dependent regulation of genes involved in epithelial-mesenchymal
transition in prostate cancer cells
Colditz, Juliane; Institute of Human Genetics, Jena University Hospital
5Protein tyrosine phosphatase expression analysis in chronic myeloid
leukemia (CML)- patient samples and cell lines
Drube, Julia; Institute of Molecular Biology, Jena University Hospital
6Bidirectional HGF/c-Met signalling in the bladder cancer
microenvironment
Jennek, Susanne; Institute of Biochemistry II, Jena University Hospital
7A ChIP-Seq and microarray based approach identifies Wt1 target gene
Dong, Lihua; Molecular Genetics, Leibniz Institute for Age ResearchFritz Lipmann Institute (FLI)
8MCPH1 acts as a modulator of βTrCP2 to regulate mitotic entry
Liu, Xiaoqian; Leibniz Institute for Age Research - Fritz Lipmann
Institute (FLI)
13:00
Lunch Snack
13:45 OSTER SESSION 1: TUMOR CELL BIOLOGY
P
Chairs: Regine Heller, Joachim Clement
9The DNA damage independent function of NBS1 in brain development
Wang, Pei; Leibniz Institute for Age Research - Fritz Lipmann Institute
(FLI)
10DNA double-strand break induces colocalization between 53BP1 and
S100A11
Bayer, Cathrin; Working group Biomolecular Photonics, Jena University
Hospital
11 BIRC3 aberrations in chronic and B-cell acute lymphocytic leukemia patients Alhourani, Eyad; Institute of Human Genetics, Jena University Hospital
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12Relevance of ITIH5 for cervical carcinogenesis
Dittmann, Jessica; Department of Gynecology, Jena University Hospital
13MLL gene displaying an important molecular biomarker in acute
leukaemia
Othman, Moneeb A.K.; Institute of Human Genetics, Jena University
Hospital
14 Detection of cervical carcinoma specific biomarkers by digital PCR Carow, Katrin; Department of Gynecology, Jena University Hospital
15Abnormal expression of keratin 19 in lung carcinoma cell lines
Wölfel, Cornelius; Institute of Pathology, Jena University Hospital
16The role of SKAP in mitosis
Vranesic, Anita Cindric; Institute of Biochemistry II, Jena University
Hospital
17Desmocollin 3 acts as a tumor suppressor through inhibiting PI3K/AKT/
MDM2 signaling in human colorectal cancer
Ma, Yunxia; Institute of Pathology, Jena University Hospital
POSTER SESSION 2: TUMOR DIAGNOSTIC AND THERAPY
Chairs: Karlheinz Friedrich, Marcus Franz
18Synthesis and biological behavior of O,S-chelating platinum(II) and
ruthenium(II) complexes
Hildebrandt, Jana; Institute of Inorganic and Analytical Chemistry, Jena
University
19FAS-Expression and survival as possible predictors in Human
Glioblastoma?
Vestergaard, Anita-Maria; AG Experimentelle Neuroonkologie, Klinik für
Neurochirurgie, Jena University Hospital
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20EGCG induces cell death in human glioblastoma cell cultures
Kögler, Christine; AG Experimentelle Neuroonkologie, Klinik für
Neurochirurgie, Jena University Hospital
21Novel cryptic rearrangements in adult B-cell precursor acute
lymphoplastic leukemia involving MLL-gene
Rittscher, Katharina; Institute of Human Genetics, Jena University
Hospital
22Tumour comorbidities in polycystic kidney disease
Joorabchi, Samrand; Institute of Pathology, Jena University Hospital
23Role of protein tyrosine phosphatases in the development of
antiangiogenic therapy resistance in renal cell carcinoma
Weiland, Anne; Institute for Molecular Cell Biology, Centre for
Molecular Biomedicine (CMB), Jena University Hospital
24 Activated gamma/delta (γδ) T cell subsets after Salmonella stimulation
Polasky, Christina; Institute of Molecular Pathogenesis, FriedrichLoeffler-Institut (FLI)
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25Effect of the autophagy inhibitor chloroquine on gefitinib-resistant lung
cancer cells and clinical relevance of autophagy-associated proteins
Schnitzler, Kai-Leonie; Institute of Pathology, Jena University Hospital
26Does epithelial to mesenchymal transition influence ALA accumulation
in bladder cancer cells?
Schleier, Richard; Institute of Pathology, Jena University Hospital
27Heterogeneous response in cellular survival to MTX-MNP and
hyperthermia exposure
Pömpner, Nadine; Institute of Diagnostic and Interventional Radiology,
Jena University Hospital
POSTER SESSION 3: TUMOR MICROENVIRONMENT AND EPIGENETIC
REGULATION
Chairs: Yuan Chen, Thomas Liehr
28Serum-depletion affects protein trophoblast expression, resembling a
tumoral adaptive switch
Novoa-Herran, S; Placenta-Labor, Department of Obstetrics, Jena
University Hospital
29Methylation of specific genes in the course of cervical carcinogenesis:
correlation to gene expression
Eiselt, Juliane; Department of Gynecology, Jena University Hospital
30Characterization of genes related to cisplatin-resistance in ovarian
carcinoma cell lines
Kritsch, Daniel; Department of Gynecology, Jena University Hospital
31Influence of soy phytoestrogens on the uterine gene expression in mice
Favaro, Rodolfo R; Placenta-Labor, Department of Obstetrics, Jena
University Hospital
32Coated superparamagnetic nickel nanorods affect cell vitality and
intracellular signalling
Schmidt, Ann-Kathrin; Abt. Hämatologie und Internistische Onkologie,
Jena University Hospital
33Raman spectroscopical investigations of senescence in human primary
fibroblast cells
Eberhardt, Katharina; Leibniz Institute of Photonic Technology (IPHT)
Jena
34Proteasomal decline in endothelial senescence
Meçe, Odeta; Institute for Molecular Cell Biology, Centre for Molecular
Biomedicine (CMB), Jena University Hospital
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35Angiogenesis is dependent on endothelial autophagy – the role of
AMPK
Spengler, Katrin; Institut for Molecular Biology, Centre for Molecular
Biomedicine (CMB), Jena University Hospital
36Sodium-hydrogen exchanger NHE1 in endothelial cells regulates
angiogenesis
Kryeziu, Nderim; Institute for Molecular Cell Biology, Centre for
Molecular Biomedicine (CMB); Jena University Hospital
37Multicellular spheroids: A model for nanoparticle-cell interaction
studies
Demut, Johanna; Abt. Hämatologie und Internistische Onkologie, Jena
University Hospital
15:00 O
RAL PRESENTATIONS
SESSION 2: TUMOR DIAGNOSTIC AND THERAPY
Chairs: Ferdinand von Eggeling, Susanne Jennek
38 Functional analysis of CAMK2N1 and RUNX3 in Ovarian Carcinogenesis
Heinze, Karolin; Department of Gynecology, Jena University Hospital
39Measuring G protein signaling with a fluorescence-based membrane
potential assay
Günther, Thomas; Department of Pharmacology and Toxicology, Jena
University Hospital
40 MALDI-Imaging: Mapping the cancer
Hoffmann, Franziska; ENT Department, Jena University Hospital
41 Classification and prediction of liver cancer by Raman imaging
Tolstik, Tatiana; Department of Internal Medicine IV, Division of
Gastroenterology, Hepatology and Infectious Diseases, Jena University
Hospital
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42The expression of the protein lysine demethylases KDM1A, KDM2B,
KDM5B and KDM6B is associated with poor clinical outcome in
childhood acute lymphoblastic leukaemia
Walter, Elisabeth; Department of Paediatric Haematology and
Oncology, Children’s Hospital; Jena University Hospital
43Inhibition of Breast Cancer Proliferation by Androgen Receptor
Antagonists
Luko, Katarina; Institute of Human Genetics, Jena University Hospital
44Molecular analysis of CETCs in patients with hepatocellular carcinoma
Berger, Tina; Abt. Hämatologie und Internistische Onkologie, Jena
University Hospital
45Detection of fetal fibronectin variants in patients’ serum: Implications
for individualized targeted tumor therapy using armed antibodies
Ospel, Johanna; Department of Internal Medicine I, Jena University
Hospital
17:00 Break
17:30
Dinner / Awards
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Institute of Pathology, Jena University Hospital
Prof. Dr. Iver Petersen, Prof. Dr. Alexander Berndt
Phone: +49-(3641)-934002
Email: [email protected]
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