Victor D. Varner - Princeton University

Victor D. Varner
Princeton University
Chemical & Biological Engineering
315 Hoyt Laboratory, William St
Princeton, NJ 08544
(609) 258-8222
[email protected]
Education
Postdoc, Chemical & Biological Engineering, Princeton University
current
Ph.D., Biomedical Engineering, Washington University
2011
M.S., Biomedical Engineering, Washington University
2008
B.S., Mechanical Engineering, Texas A&M University
2003
Research Experience
Postdoctoral fellow with Celeste Nelson, Princeton University
Mechanical control of airway branching morphogenesis in the
developing mouse lung.
2012-present
Graduate student with Larry Taber, Washington University
Mechanics of heart tube formation in the early chick embryo.
2005-2011
Project engineer with Lockheed Martin, Human Research Facility, NASA
Johnson Space Center
Support of human life science experiments on International Space
Station.
2004-2005
Research assistant with Harry Hogan, Texas A&M University
Mechanical testing and μCT imaging of cancellous bone in hindlimb
unloaded rats.
2003-2004
Honors, Awards and Fellowships
New Faculty Boot Camp, Society for Developmental Biology
2014
Mentor, CHOOSE DEVELOPMENT! Undergraduate Research Program,
Society for Developmental Biology/National Science Foundation
2013-2014
American Heart Association Predoctoral Fellowship
2009-2011
Graduated Magna Cum Laude, Texas A&M University
2003
Dean’s Honor Award, Dwight Look College of Engineering, Texas A&M
University
2003
McFadden Scholarship, University Honors Program, Texas A&M University
1
1999-2003
Publications
Varner, V.D., Nelson, C.M. (2014) Cellular and physical mechanisms of branching morphogenesis. Development, 141(14):2750-2759. (Paper featured in “In This Issue”
highlights.)
Varner, V.D., Nelson, C.M. (2014) Toward the directed self-assembly of engineered tissues. Annu Rev Chem Biomol Eng, ;5:507-26.
Varner, V.D., Xu, G., Taber, L.A. (2014) Shape is not enough to test hypotheses for
morphogenesis. In Residual Stress, Thermomechanics & Infrared Imaging, Hybrid
Techniques and Inverse Problems, Volume 8, Conference Proceedings of the Society
for Experimental Mechanics Series, (eds. Rossi, M. et al.), in press.
Wyczalkowski, M.A., Varner, V.D., Taber, L.A. (2013) Computational and experimental
study of the mechanics of embryonic wound healing. J Mech Behav Biomed Mater,
28:125-46.
Varner, V.D., Nelson, C.M. (2013) Let’s push things forward: disruptive technologies and
the mechanics of tissue assembly. Integr Biol, 5:1162-1173.
Piotrowski, A., Varner, V.D., Gjorevski, N., Nelson, C.M. (2013) Three-dimensional traction force microscopy of engineered epithelial tissues. In Tissue Morphogenesis (Methods in Molecular Biology series) (ed. Nelson, C.M.) New York: Springer, in press.
Kim, H.Y.*, Varner, V.D.*, Nelson, C.M. (2013) Apical constriction initiates new bud
formation during monopodial branching of the embryonic chicken lung. Development,
140(15):3146-3155. (* These authors contributed equally to this paper.)
Wyczalkowski, M.A., Chen, Z., Filas, B.A., Varner, V.D., Taber, L.A. (2012) Computational models for mechanics of morphogenesis. Birth Defects Res C Embryo Today,
96(2):132-52.
Varner, V.D., Taber, L.A. (2012). On integrating experimental and theoretical models
to determine physical mechanisms of morphogenesis. BioSystems, 109(3):412-9.
Varner, V.D., Taber, L.A. (2012). Not just inductive: a crucial mechanical role for the endoderm during heart tube assembly. Development, 139(9):1680-90. (Paper featured
in “In This Issue” highlights.)
Yao, J., Varner, V.D., Brilli, L.B., Young, J.M., Taber, L.A., Perucchio, R. (2012).
Viscoelastic material properties of the myocardium and cardiac jelly in the looping
chick heart. J Biomech Eng, 134(2):024502.
Filas, B.A., Varner, V.D., Voronov, D.A., and Taber, L.A. (2011). Tracking morphogenetic tissue deformations in the chick embryo. J Vis Exp, (56):e3129.
2
Varner, V.D., Voronov, D.A., Taber, L.A. (2010). Mechanics of head fold formation:
investigating tissue-level forces during early development. Development, 137(22):380111. (Paper featured in “In This Issue” highlights and editorial by Editorin-Chief Olivier Pourqui´
e)
Varner, V.D., Taber, L.A. (2010). On measuring stress distributions in epithelia. In
IUTAM Symposium on Cellular, Molecular and Tissue Mechanics (ed. K. Garikipati
and E. M. Arruda), 45-54. New York: Springer.
Invited Presentations
Varner, V.D., Voronov, D.A., Taber, L.A. (2011) Mechanics of head fold formation:
investigating tissue-level forces during early development, Experimental Biology 2011,
Washington D.C. (April)
Varner, V.D., Voronov, D.A., Taber, L.A. (2010) Mechanics of head fold formation: investigating tissue-level forces during early development, Biomedical Engineering Seminar,
Saint Louis University (October)
Varner, V.D., Voronov, D.A., Taber, L.A. (2010) Mechanics of head fold formation:
investigating tissue-level forces during early development, Anatomy and Cell Biology
seminar, University of Kansas Medical Center (February)
Contributed Presentations
Varner, V.D., Gleghorn, J.P., Nelson, C.M. (2014) Airway branching morphogenesis
driven by a growth-induced mechanical instability, 7th World Congress of Biomechanics, Boston, MA (July)
Varner, V.D., Gleghorn, J.P., Nelson, C.M. (2013) Physical mechanism for lung branching morphogenesis revealed by 3D traction force microscopy, Biomedical Engineering
Society, Annual Meeting, Seattle, WA (September)
Varner, V.D., Taber, L.A. (2010) Morphomechanics of embryonic heart tube formation,
Biomedical Engineering Society, Annual Meeting, Austin, TX (October)
Varner, V.D., Voronov, D.A., Taber, L.A. Mechanics of head fold formation in the early
chick embryo, 16th International Conference on Mechanics in Medicine and Biology,
Pittsburgh, PA (July)
Professional Societies
American Society of Mechanical Engineers (ASME)
Biomedical Engineering Society (BMES)
Society for Developmental Biology (SDB)
American Society of Cell Biology (ASCB)
3
Teaching/Mentoring Experience
Research Mentor, CHOOSE DEVELOPMENT! Undergraduate Research
Program, Princeton University
Competitive national program, funded by the Society for
Developmental Biology and National Science Foundation,
which targets students from underrepresented minorities
interested in Ph.D. programs related to developmental biology.
2013-2014
Mentoring high school, undergraduate, senior thesis and graduate students, 2012-present
Princeton University
Teaching Assistant, BME 559: Intermediate Biomechanics,
Washington University
Guest Lecturer, BME 568: Cardiovascular Dynamics,
Washington University
Teaching Assistant, BME 240: Biomechanics,
Washington University
2009
2008, 2010
2007
Service
Member of the ASME Tissue & Cellular Engineering Committee
Science Saturday Conversations, St. Louis, MO
Outreach to discuss research and career opportunities
in science with local high school students.
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2011 - present
2009