メチル化遺伝子プロファイルはこちら

膀胱がん
ATM
BRCA1
BRCA2
CD44
CDH13
CDKN2A
CHFR
ESR1
GATA5
GSTP1
MGMT-1
MGMT-2
MSH6
P53
P73
PAX6
PTEN
PYCARD
RARB
RB1-1
RB1-2
STK11
THBS1
VHL
WT1
40.7
72.5
56
38.5
62.6
24.2
18.7
49.5
55
40.7
64.8
67
81.3
46.2
37.4
20.9
31.9
28.6
59.3
27.5
23.1
94.5
25.3
31.9
58.2
膀胱がん
100
90
80
70
60
50
40
30
20
10
0
引用文献：Evaluation of the Methylation Status of Tumour Suppressor Genes
for Predicting Bacillus Calmette-Gue´rin Response in Patients With
T1G3 High-Risk Bladder Tumours
結腸・直腸がん
APC
CDH13
CDKN2A(P16)
CDKN2B
CHFR
ESR1
HIC1
MLH1
RARB
RASSF1
TIMP3
18.6
53.5
2.3
2.3
37.2
67.4
16.3
48.8
37.2
16.3
9.3
結腸・直腸がん
100
90
80
70
60
50
40
30
20
10
0
引用文献：Evaluation of the Methylation Status of Tumour Suppressor Genes
for Predicting Bacillus Calmette-Gue´rin Response in Patients With
T1G3 High-Risk Bladder Tumours
胃がん
胃がん
APC
CDKN2A
CHFR
GSTP1
MGMT
MLH1
P73
RARB
RASSF1
TIMP3
52.9
36
65
20.6
36.8
72.9
24
50.7
61.8
13.2
100
90
80
70
60
50
40
30
20
10
0
APC
CDKN2A
CHFR
GSTP1
MGMT
MLH1
P73
RARB
RASSF1
TIMP3
引用文献：Gene methylation in gastric cancer
乳がん
APC
BRCA1
CASP8
CD44
CDH13
CDKN2B
DAPK1
ESR1
FHIT
GSTP1
HIC1
MLH1
RARB
RASSF1
TIMP3
VHL
10.4
5.2
7.8
2.6
1.3
14.3
14.3
2.6
1.3
40.2
1.3
3.9
3.9
48
5.2
1.3
乳がん
100
90
80
70
60
50
40
30
20
10
0
引用文献：Prediction of BRCA2-association in hereditary
breast carcinomas using array-CGH
上咽頭癌
上咽頭癌
CADM1
CDH13
CDKN2A
CHFR
DAPK1
RASSF1
69.8
77.4
66
58.5
79.2
75.5
100
80
60
40
20
0
引用文献：Epigenetic markers for early detection of　nasopharyngeal
carcinoma
in a high risk　population
子宮頸癌(扁平上皮癌）
子宮頸癌
(扁平上皮癌）
APC
CDKN2A
DAPK1
ESR1
FHIT
HIC1
MGMT
MLH1
RARB
RASSF1
TIMP3
10
32
59
31
9
18
18
2
26
8
6
100
90
80
70
60
50
40
30
20
10
0
引用文献：Utility of Methylation Markers in Cervical Cancer Early
Detection:
子宮頸癌（腺癌）
APC
CDKN2A
DAPK1
ESR1
FHIT
HIC1
MGMT
MLH1
RARB
RASSF1
TIMP3
51
26
34
31
0
49
22
8
14
26
53
子宮頸癌（腺癌）
100
80
60
40
20
0
引用文献：Utility of Methylation Markers in Cervical Cancer Early
Detection:
Appraisal of the State-of-the-Science

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