MI BITON I NVESTS I N NOVEL LI FE SCI ENCES I N FRASTRUCTU RE C ontent The Hague, 19 December 2014 Mibiton facility SurgVision BV >> Revolving Mibiton Fund invests in the Life Sciences infrastructure of SurgVision, Cristal Therapeutics, Flowid and Genalice Mibiton facility Cristal Therapeutics BV >> Mibiton facility Flowid BV >> Please find below an overview of our most recent investments, which fortify the product-development infrastructure at four innovative Dutch Life Science companies. In 2015, we will continue our 20-years revolving investment policy to strengthen the Dutch Life Sciences community. Mibiton facility Genalice BV >> Mibiton Share, Solo and Science funds >> Groningen investment Multispectral Normalized Imaging System enabling real time surgery guidance SurgVision is a spin-off company of the Technical University of Munich and has recently signed a clinical collaboration agreement with the University Medical Center Groningen. The company develops innovative real-time imaging technology to assist in the complete removal of cancerous tumour tissue during surgery. The SurgVision Imaging Platform is a technology called ‘Multispectral Normalized Imaging’, which combines hardware, intelligent software algorithms and fluorescently-labelled antibodies. Mibiton will finance three advanced instrumental clinical set-ups. Ton van den Hoven: “SurgVision is pleased to have Mibiton’s support, which enables the placement of three advanced clinical imaging platforms within well-renowned institutions. This will help to meet the milestones in the process of taking this new technology to the market. It will also enable SurgVision to direct its working capital towards completing the clinical schedule.” Contact information: Surgvision B.V. Dalhuysenstraat 37 8448 EW HEERENVEEN +31(0)6 11 78 78 55 [email protected] www.surgvision.com << Maastricht investment Laboratory Equipment for the novel Cristal Therapeutics facility at the BioPartner Centre Maastricht Cristal Therapeutics is a pharmaceutical company developing a new class of nanomedicines based on its polymeric technology platform CriPec®. The application of CriPec® results in better efficacy and improved tolerability of drugs by improved disposition in the body and controlled exposure to the sites of action. The first product in development by Cristal Therapeutics is the CriPec® docetaxel for the treatment of solid tumours. In addition to CriPec® docetaxel, the Cristal Therapeutics product portfolio comprises various early-stage products in various therapeutic areas. Cristianne Rijcken: “With the Mibiton investment, our laboratories can be equipped to enable the pharmaceutical development of novel CriPec®-based products. More specifically, the focus is on organic synthesis, formulation and stability studies and corresponding analytical evaluations and product characterisation. The in-house equipment is highly instrumental in the development of the first product CriPec® docetaxel towards clinical evaluation and further expansions of the CriPec® platform into other product opportunities, also for third parties.” Contact information: Cristal Therapeutics B.V. Cristianne Rijcken Oxfordlaan 55 6229 EV MAASTRICHT +31 (0)43 388 5868 [email protected] www.cristaltherapeutics.com << Eindhoven investment Spinning Disc Production - SpinPro Flowid specializes in optimizing and developing production systems for the pharmaceutical and (bio)chemical industry. The Eindhoven University of Technology’s spin-off has recently developed a pilot-size continuous plants platform ‘SpinPro’, which can be used for the full-scale production of (bio)chemicals and pharmaceuticals. SpinPro is based on the so-called ‘spinning disc technology’. The system is available as a reactor, particularly suited for multi-phase reactions, and as an extractor for the purification of medication, oils, natural ingredients and so much more. The Mibiton investment will enable Flowid to manufacture a second generation of SpinPro equipment. Wouter Stam: “Mibiton helps us to expand our business with the funding of two second generation SpinPro modular plants.” Contact information: Flowid B.V. Postbus 513 Matrix MA 1.26-1.30 5600 MB EINDHOVEN +31 (0)6 24 67 97 74 [email protected] www.flowid.nl << Gelderland investment Accelerate configuration of GENALICE VAULT servers to process Next Generation Sequencing Data GENALICE is a biomedical big data company with headquarters in Harderwijk, Gelderland. The company designs and builds groundbreaking software solutions for ultra-fast, highly accurate and cost-effective DNA data processing and analysis on general-purpose hardware. The lead product, GENALICE MAP, designed to effectively process Next Generation Sequencing (NGS) data, is deployed on an all-inone appliance, the GENALICE VAULT. To tailor the NGS data procession solution to specific needs, five configurations are available, enabling the storage and processing of 500 (XS) to 10,000 (XL) full Human Genomes. Mibiton will finance the hardware components of a number of GENALICE VAULT systems in order to accelerate market acceptance. Jos Lunenberg, Chief Business Officer, is very pleased with the loan agreement provided by Mibiton, and commented as follows: “For a high potential company like GENALICE, active in an extremely dynamic market, reducing the time to market is essential. The support of Mibiton enables us to speed up our product delivery at exactly the right moment. The acceptation process for this agreement was fast and the funds were transferred to our bank account before the ink was dry.” Contact information: Genalice B.V. Deventerweg 9d 3843 GA HARDERWIJK +31 (0)88 122 1000 [email protected] www.genalice.com << Mibiton Share, Solo and Science funds Are you as a Life Sciences SME planning to invest in facilities or equipment to start or extend your business activities? Financial arrangements by the Mibiton Solo fund will enable you to buy specialized or more general equipment to furnish your laboratory. With the Mibiton Share or Science funds, you can finance collaborations to share the exploitation of high value Life Sciences facilities. [email protected] www.mibiton.nl <<
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