Reference Point Indentation Presentations Pre-Meeting Presentations Page 1 ROOM 310 | THURSDAY 1:30PM - 2:45PM Bone Material Properties in Type 2 Diabetes: Is Skeletal Deterioration Another Diabetic Complication? Sundeep Khosla, MD, Mayo Clinic, USA ROOM 310 | 1:15PM - 1:30PM Loss of Nf1 in Osteoprogenitors Affects Fracture Resistance at Multiple Levels of Bone Organization. Mathilde Granke*1, Jean de la Croix Ndong2, Sasidhar Uppuganti2, Guillaume Vignaux2, Alexander Makowski3, Daniel Perrien1, Florent Elefteriou2, Jeffry Nyman1 1Vanderbilt University Medical Center, USA, 2Vanderbilt University, USA, 3Department of Veterans Affairs Vanderbilt University, USA GRAND BALLROOM A | SATURDAY 4:45PM - 5:00PM Bone Material Strength as measured by microindentation in vivo is decreased independently of BMD in patients with fractures. Frank Malgo*1, Neveen Hamdy2, Socrates Papapoulos2, Natasha Appelman-dijkstra3. 1Leiden University Medical Center, Netherlands, 2Leiden University Medical Center, The Netherlands, 3LUMC Centre for Bone Quality Dept of Endocrinology, The Netherlands ROOM 351D | MONDAY Poster Presentations SUNDAY Page 3 DISCOVERY HALL (HALL E) | 12:30PM - 2:30PM [SU0020] Association Between Reference Point Indentation Measures and Cortical Bone Composition, Bending Properties, and Fracture Toughness. Oral Presentations FRIDAY Reference Point Indentation Presentations 11:30PM - 12:30PM Lamya Karim*1, Nathalie Portero-Muzy2, Daniel Brooks3, Evelyne Gineyts2, Pascale Chavassieux4, Roland Chapurlat5, Mary Bouxsein1. 1Beth Israel Deaconess Medical Center, Harvard Medical School, USA, 2Universite de Lyon, France, 3Beth Israel Deaconess Medical Center, USA, 4INSERM UMR1033, Universite De Lyon, France, 5E. Herriot Hospital, France [SU0023] Differences in Assessment of Micro-Indentation Resistance between BioDent and OsteoProbe. Mathilde Granke*1, Sasidhar Uppuganti2, Mary Katherine Manhard2, Mark Does2, Donald Lee2, Daniel Perrien1, Jeffry Nyman1. 1Vanderbilt University Medical Center, USA, 2Vanderbilt University, USA [SU0041] Cx43 Scaffolding C-Terminus Intracellular Domain Is Required for Achieving Proper Bone Architecture and Strength, but It Does Not Mediate the Effect of Osteocytic Cx43 on Cortical Bone. Rafael Pacheco* , Iraj Hassan2, Chad Sorenson2, Hannah Davis2, Max Hammond3, Rejane Reginato4, Eduardo Katchburian4, Joseph Wallace5, Teresita Bellido6, Lilian Plotkin6. Meet-the-Professor Session: In Vivo Microindentation Mary Bouxsein, Ph.D. Beth Israel Deaconess Medical Center, Harvard Medical School, USA 1Indiana University School of Medicine, Federal University of Sa o Paulo, USA, Indiana University School of Medicine, USA, Purdue University, USA, 4Federal University of Sa o Paulo, Brazil, 5Indiana University Purdue University Indianapolis (IUPUI), USA, 6Indiana University School of Medicine, USA TRY OsteoProbe® RUO and BioDent™ AT BOOTH #314 TRY OsteoProbe® RUO and BioDent™ AT BOOTH #314 Reference Point Indentation Presentations Reference Point Indentation Presentations Page 2 Poster Presentations FRIDAY DISCOVERY HALL (HALL E) | 5:30PM - 7:00PM Poster Presentations Page 4 DISCOVERY HALL (HALL E) | SUNDAY 12:30PM - 2:30PM Leiden University Medical Center, The Netherlands [SU0273] Pannexin 1 Knockout Mice Have Reduced RANKL Expression Following Focal Microinjury: Possible Mechanism Involving Pannexin 1 Channels for Osteoclast Recruitment?. [FR0414] Bone Properties in Type 2 Diabetes are Associated with the Advanced Glycation Endproduct Pentosidine 1City College of New York, USA, 2Albert Einstein College of Medicine, USA, 3City College of New York, USA, 4City College of New York, USA [FR0290] Micro-indentation in vivo captures elements of bone fragility independently of BMD - YOUNG INVESTIGATOR AWARD Natasha Appelman-dijkstra*, Frank Malgo, Socrates Papapoulos, Neveen Hamdy. Dorothy Fink*1, Jessica Furst2, Chiyuan Zhang3, Laura Beth Anderson3, Hongfeng Jiang4, Serge Cremers3, Kyle Nishiyama3, Hua Zhou5, David Dempster6, Atharva Poundarik7, Shonni Silverberg3, Deepak Vashishth8, Mishaela Rubin3. Wing-Yee Cheung*1, Eliana Scemes2, David Spray2, Jelena Basta-Pljakic3, Robert Majeska4, Mitchell Schaffler1. MONDAY DISCOVERY HALL (HALL E) | 12:30PM - 2:30PM 1NYP-Columbia, USA, 2Columbia University College of Physicians & Surgeons, USA, 3Columbia University, USA, 4Columbia University College of Physician & Surgeons, USA, 5Helen Hayes Hospital, USA, 6Columbia University, USA, 7Rensselaer Polytechnic University, USA, 8Rensselaer Polytechnic Institute, USA [MO0028] Patients with stress fractures exhibit impaired bone material properties by microindentation SATURDAY 1Ph.D., Norway, 2Oslo University Hospital, Norway DISCOVERY HALL (HALL E) | 12:30PM - 2:30PM Daysi Duarte Sosa*1, Erik Fink Eriksen2. [SA0030] Glycation alters material properties of diabetic mice at multiple length scales [MO0028] The Femoral Neck Strength of Post-menopausal Women is Predicted by Factors at Multiple Length Scales. 1Rensselaer Polytechnic University, USA, 2Rensselaer Polytechnic Institute, USA, 3Columbia University, USA 1Washington University at St.Louis, USA, 2Washington University in St Louis, USA, 3Washington University in St.Louis, USA Atharva Poundarik*1, Grazyna Sroga2, Mishaela Rubin3, Deepak Vashishth2. [SA0290] Microindentation in vivo captures elements of bone fragility independently of BMD Natasha Appelman-dijkstra*1, Frank Malgo2, Socrates Papapoulos1, Neveen Hamdy1 1Leiden University Medical Center, The Netherlands, 2Leiden University Medical Center, Netherlands SUNDAY DISCOVERY HALL (HALL E) | 12:30PM - 2:30PM [SU0019] Age Related Changes in the Structure, Composition and Properties of Porcine Cortical Bone. Iwona Jasiuk*1, Michael Chittenden2 1University of Illinois at Urbana-Champaign, USA, 2University of Illinois, USA TRY OsteoProbe® RUO and BioDent™ AT BOOTH #314 Adam Abraham*1, Simon Tang2, Avinesh Agarwalla3 [MO0277] Deletion of ephrinB2 in osteocytes leads to increased trabecular bone mass, but reduced bone strength. Christina Vrahnas1, Stephen Tonna2, Huynh Nguyen3, Mark Forwood3, T John Martin4, Natalie Sims*5 Australia, 2St Vincent’s Institute, Australia, 3Griffith University, Australia, 4St. Vincent’s Institute of Medical Research, Australia, 5St. Vincent’s Institute of Medical Research, Australia TRY OsteoProbe® RUO and BioDent™ AT BOOTH #314 www.activelifescientific.com | +1.888.906.7770 Toll Free | Santa Barbara, CA | Booth #314
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