生体情報分子解析学在席教員の研究業績 [過去10年間の原著論文] 現教員:三輪匡男、菅谷純子、五十里彰、山崎泰広; 転出教員:前田利男、吉成浩一、高橋忠伸 1997年 1. Katherine M. Howard, Joseph E. Miller, Masao Miwa, Merle Olson: Cell-specific regulation of expression of plasma-type platelet-activating factor acetylhydlolase in the liver. J. Biol. Chem. 272, 27543-27548 (1997) [IF 5.854] 2. Toshiaki Minami, Junko Sugatani, Kenji Sakimura, Manabu Abe, Masayoshi Mishina, Seiji Ito: Absence of prostaglandin E2-induced hyperalgesia in NMDA receptor ε subunit knockout mice. Br. J. Pharmacol., 120, 1522-1526 (1997) [IF 3.410, Citation 24] 3. Mami Ueda, Junko Sugatani, Sawako Unezaki, Yoshie Ito, Hirohiko Miki, Masanobu Uyama, Seiji Ito: Involvement of prostaglandin E2 in rabbit corneal injury by anterior segment ischemia. Prostagl. Leukotr. Essentl. Fatty Acids, 57(3), 285-291 (1997) [IF 1.801, Citation 2] 4. Hideki Sakai, Takashi Sato, Noriko Hamada, Miyuki Yasue, Akira Ikari, Bunpei Kakinoki, Noriaki Takeguchi: Thromboxane A2, released by the anti-tumour drug irinotecan, is a novel stimulator of Cl- secretion in isolated rat colon. J. Physiol. (London), 505, 133-144 (1997) 5. Akira Ikari, Hideki Sakai, Noriaki Takeguchi: ATP, thapsigargin and cAMP increase Ca2+ in rat hepatocytes by activating three different Ca2+ influx pathways. Jpn. J. Physiol., 47, 235-239 (1997) 1998年 1. Hong Xu, Kazumoto Iijima, Shunichi, Shiozawa, Ryojiro Tanaka, Yuji Inoue, Taku Shirakawa, Kaoru Nishiyama, Masao Miwa, Hajime Nakamura, Norishige Yoshikawa: Platelet- activating factor acetylhydrolase gene mutation in Japanese nephrotic children. Kidney International, 54, 1867-1871 (1998) 2. Yumi Munemoto, Hiromichi Kuriyama, Tadashi Doi, Kazuo Sato, Ayumi Matsumoto, Junko Sugatani, Hisayuki Cho, Mototane Komeda, Richard A. Altschuler, Masanori Kitajiri, Masayoshi Mishina, Toshio Ymashita: Auditory pathway and auditory brainstem response in mice lacking NMDA receptor ε1 and ε4 subunits. Neurosci. Lett., 251, 101-104 (1998) [IF 1.898, Citation 7] 3. Masaki Akiyama, Junko Sugatani, Takashi Suzuki, Yasuo Suzuki, Masao Miwa: Identification of a major PAF acetylhydrolase in human serum/plasma as a 43 kDa glycoprotein containing about 9 kDa aspargine-conjugated sugar chain(s). J. Biochem., 123, 786-789 (1998) [IF 1.827, Citation 7] 4. Masahiro Suzuki, Junko Sugatani, Mitsuhiro Ino, Masahiko Shimura, Masaki Akiyama, Ryuta Yamazaki, Yasuo Suzuki, Masao Miwa: Continuous binding of the PAF molecule to its receptor is necessary for the long-term aggregation of platelets. Am. J. Physiol., 274(Cell Physiol.43), C47-C57 (1998) [IF 3.842, Citation 8] 5. Hideki Sakai, Akira Ikari, Tomiyuki Shimizu, Takashi Sato, Noriaki Takeguchi: Cyclic GMP-dependent cytoprotection against ethanol-induced damage in rabbit isolated gastric parietal cells. Eur. J. Pharmacol., 361, 109-117, (1998) 6. Akira Ikari, Hideki Sakai, Noriaki Takeguchi: Protein kinase C-mediated up-regulation of Na+/Ca2+-exchanger in rat hepatocytes determined by a new Na+/Ca2+-exchanger inhibitor, KB-R7943. Eur. J. Pharmacol., 360, 91-98 (1998) 1999年 1. Chris Lee, Farhad Sigari, Theresa Segrado, Sohvi Horkko, SusanHama, P.V. Subbaiah, Masao Miwa, Mohamad Navab, Joseph L. Witztum, Peter D. Reaven: All apoB-containing lipoproteins induce monocyte chmotaxis andadhesion when minimally modified: Modulation of lipoprotein bioactivity by platelet-activating factor acetylhydrolase. Artherioscler Thromb. Vasc. Biol., 19, 1437-1446, (1999) 2. Ryojiro Tanaka, Kazumoto Iijima, Hong Xu, Yuji Inoue, Ryusuke Murakami, Taku Shirakawa, Kaoru Nishiyama, Masao Miwa, Norishige Yoshikawa: Role of platelet-activating factor acetylhydrolase gene mutation in Japanese children IgA nephrophaty. Am. J. Kidney Dis., 34 (2), 289-295 (1999) 3. Veedamali S. Subramanian, Jaya Goyal, Masao Miwa, Junko Sugatani, Masaki Akiyama, Ming Liu, Papasani V Subbaiah: Role of lecithin-cholesterol acyltransferase in the metabolism of oxidized phospholipids in plasma: studies with platelet-activating factor-acetylhydrolase deficient plasma. Biochim. Biophys. Acta 1439, 95-109 (1999) [IF 2.751, Citation 25] 4. Manabu Watanabe, Takayuki Kaihatsu, Masao Miwa, Toshio Maeda: Ca2+/calmodulin-dependent protein kinase II inhibitors potentiate superoxide production in polymorphonuclear leukocytes. J. Pharm. Pharmacol. 51, 295-300 (1999) 5. Toshiyuki Yasui, Tetsuo Mukakami, Toshio Maeda, Takami Oka: Involvement of gonadal steroid hormone disturbance in altered prolactin receptor gene expression in the liver of diabetic mice. J. Endocrinol. 161, 33-40 (1999) 6. Akira Ikari, Hideki Sakai, Akiko Tanaka, Atsushi Ikeda, Kanako Inoue, Noriaki Takeguchi: Prostaglandin E2-activated housekeeping Cl- cannels in the basolateral membrane of rat gastric parietal cells. Jpn. J. Physiol., 49, 365-372 (1999) 7. Akira Ikari, Hideki Sakai, Takahiro Sato, Noriaki Takeguchi : Thromboxane A2 receptor linked with the Ca2+ pathway in rat colonic crypt cells. Biochem. Biophys. Res. Commun., 258, 708-712 (1999) 2000年 1. Masanori Kuroyanagi, Kenichi Yoshida, Atsushi Yamamoto and Masao Miwa: Bicyclo[3.2.1] octane and 6-oxabicyclo[3.2.2]nonane type neolignans from Magnolia denudata. Chem. Pharm. Bull. 48, 832-837 (2000) 2. Hong Xu, Kazumoto Iijima, Taku Shirakawa, Shunichi Shiozawa, Masao Miwa, Kanji Yamaoka, Naohisa Kawamura, Hajime Nakamura and Norishige Yoshikawa: Platelet-activating factor acetylhydrolase gene mutation in Japanese children with Escherichia coli O157-associated hemolytic uremic syndrome. Am. J. Kidney Disease 36, 42-46 (2000) 3. Yukiko Mizutani, Keiko Tamiya-Koizumi, Fumitoshi Irie, Yoshio Hirabayashi, Masao Miwa: Cloning and expression of rat neutral sphingomyelinase: enzymological characterization and identification of essential histidine residues. Biochim. Biophys. Acta 1485, 236-246 (2000) [IF 2.751] 4. Naoki Unno, Toshio Nakamura, Hiroshi Kaneko, Takashi Uchiyama, Naoto Yamamoto, Junko Sugatani, Masao Miwa and Satoshi Nakamura: Plasma platelet-activating factor acetylhydrolase deficiency is associated with atherosclerotic occlusive disease in Japan. J. Vasc. Surg. 32, 263-267 (2000) [IF 3.173, Citation 26] 5. Junko Sugatani, Takashi Igarashi, Machiko Munakata, Yataka Komiyama, Hakuo Takahashi, Naoko Komiyama, Toshio Maeda, Tae Takeda and Masao Miwa: Activation of coagulation in C57BL/6 mice given verotoxin 2 (VT2) and the effect of co-administration of LPS with VT2. Thromb. Res. 100, 61-72 (2000) [IF 2.012, Citation 5] 6. Junko Sugatani, Takashi Igarashi, Masahiko Shimura, Tatsuhiro Yamanaka, Tae Takeda, Masao Miwa: Disorders in the immune responses of T- and B-cells in mice administered intravenous verotoxin 2. Life Sci. 67, 1059-1072 (2000) [IF 2.512, Citation 5] 7. Junko Sugatani, Takahiro Iwai, Manabu Watanabe, Kiyotaka Machida, Toshio Tanaka, Toshio Maeda and Masao Miwa: Inhibition of rabbit platelet aggregation by nucleoside 5'-alkylphosphates: Correlation with inhibition of agonist-induced calcium influx. Biochem. Pharmacol. 60, 197-205 (2000) [IF 3.617, Citation 2] 8. Tomoyuki Suzuki, Hideki Sakai, Akira Ikari, Noriaki Takeguchi: Mobilization of intracellular Ca2+ by thromboxane A2 dose not affect Ca2+-activated K+ channels in rat colonic crypt cells. Jpn. J. Physiol., 50, 389-393 (2000) 9. Tomoyuki Suzuki, Hideki Sakai, Akira Ikari, Noriaki Takeguchi: Inhibition of thromboxane A2-induced Clsecretion by antidiarrhea drug loperamide in isolated rat colon. J. Pharmacol. Exp.Ther., 295, 233-238 (2000) 2001年 1. Junko Sugatani, Hiroyuki Kojima, Akiko Ueda, Satoru Kakizaki, Kouichi Yoshinari, Qi-Hui Geong, Ida S. Owens, Masahiko Negishi and Tatsuya Sueyoshi: The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR. Hepatology, 33, 1232-1238 (2001) [IF 9.792, Citation 121] 2. Miki Shimada, Kouichi Yoshinari, Emi Tanabe, Emi Shimakawa, Maki Kobashi, Kiyoshi Nagata, Yasushi Yamazoe: Identification of ST2A1 as a rat brain neurosteroid sulfotransferase mRNA. Brain Res., 920, 222-225 (2001) 3. Wataru Honma, Yoshiteru Kamiyama, Kouichi Yoshinari, Hironobu Sasano, Miki Shimada, Kiyoshi Nagata, Yasushi Yamazoe: Enzymatic characterization and interspecies difference of phenol sulfotransferases, ST1A forms. Drug Metab. Dispos., 29, 274-281 (2001) [IF 4.015] 4. Kouichi Yoshinari, Tatsuya Sueyoshi, Rickie Moore, Masahiko Negishi: Nuclear receptor CAR as a regulatory factor for the sexually dimorphic induction of CYB2B1 gene by phenobarbital in rat livers. Mol. Pharmacol., 59, 278-284 (2001) [IF 4.612] 5. Toshio Maeda, Rieko Sakita, Takayuki Kaihatsu and Masao Miwa: Sustained hyperglycemia and insulin resistance induced by dietary restriction. Biol. Pharm. Bull., 24, 950-953 (2001) [IF 1.317] 6. Akira Ikari, Kumiko Nakajima, Kazuya Kawano, Yasunobu Suketa: Polyvalent cation-sensing mechanism increaed Na+-independent Mg2+ transport in renal epithelial cells. Biochim. Biophys. Res. Commun., 287, 671-674 (2001) 7. Akira Ikari, Yuka Tachihara, Kazuya Kawano, Yasunobu Suketa: Differential regulation fo Na+,K+-ATPase and the Na+-coupled glucose transporter in hypertensive rat kidney. Biochim. Biophys. Acta., 1510, 118-124 (2001) 8. Hideki Sakai, Masashi Ukai, Akira Ikari, Shinji Asano, Noriaki Takeguchi: Is rabbit CLCA1 related to the basolateral Ca2+-dependent Cl- channel of gastric parietal cells? Jpn. J. Physiol., 51, 121-125 (2001) 2002年 1. Naoki Unno, Toshio Nakamura, Hiroshi Mitsuoka, Takaaki Saito, Keita Miki, Kei Ishimaru, Junko Sugatani, Masao Miwa, Satoshi Nakamura: Single nucleotide polymorphisim (G(994)-> T) in the plasma platelet-activating factor-acetylhydrolase gene is associated with graft patency of femoropopliteal bypass. Surgery, 132, 66-71 (2002) [IF 2.586, Citation 4] 2. Junko Sugatani, Kasumi Yamakawa, Kouichi Yoshinari, Takashi Machida, Hitoshi Takagi, Masatomo Mori, Satoru Kakizaki, Tatsuya Sueyoshi, Masahiko Negishi, Masao Miwa: Identification of defect in UDP-glucuronosyltransferase gene promoter and association with hyperbilirubinemia. Biochem. Biophys. Res. Commun., 292, 492-497 (2002) [IF 3.000, Citation 48] 3. Junko Sugatani, Naoko Komiyama, Toru Mochizuki, Minoru Hoshino, Daisei Miyamoto, Takashi Igarashi, Shoji Hoshi, Masao Miwa: Urinary concentrating defect in rats given Shiga toxin: elevation in urinary AQP2 level associated with polyuria. Life Sciences, 71, 171-189 (2002) [IF 2.512, Citation 5] 4. Naoki Unno, Toshio Nakamura, Hiroshi Mitsuoka, Takashi Uchiyama, Naoto Yamamoto, Takaaki Saito, Junko Sugatani, Masao Miwa, Satoshi Nakamura: Association of a G994→T missense mutation in the plasma platelet-activating factor acetylhydrolase gene with risk of abdominal aortic aneurysm in Japanese. Ann. Surg., 235, 297-302 (2002) [IF 6.328, Citation 11] 5. Toshio Nakamura, Takanori Sakaguchi, Naoki Unno, Junko Sugatani, Masao Miwa, Satoshi Nakamura: Relationship between the platelet activating factor acetylhydrolase gene and intractability of ulcerative colitis. Dis. Colon Rectum, 45, 389-393 (2002) [IF 2.264, Citation 3] 6. Hao Xiong, Kouichi Yoshinari, Kim L. R. Brouwer, Masahiko Negishi: Role of constitutive androstane receptor in the in vivo induction of Mrp3 and CYP2B1/2 by phenobarbital. Drug Metab. Dispos., 30, 918-923 (2002) [IF 4.015] 7. Hisato Iwata, Kouichi Yoshinari, Masahiko Negishi, John J. Stegeman: Species-specific responses of constitutively active receptor (CAR)-CYP2B coupling: lack of CYP2B inducer-responsive nuclear translocation of CAR in marine teleost, scup (Stenotomus chrysops). Comparative Biochemistry and Physiology C- Toxicol. Pharmacol., 131, 501-510 (2002) 8. Akira Ikari, Kumiko Nakajima, Sayuri Taki, Yasunobu Suketa: Up-regulation of Na+-dependent Mg2+ transport by nitric oxide and cyclic GMP pathway in renal epithelial cells. Eup. J. Pharmcol., 451, 133-139 (2002) 9 Akira Ikari, Mika Nakano, Kazuya Kawano, Yasunobu Suketa: Up-regulation of sodium- dependent glucose transporter by interaction with heat shock protein 70. J. Biol. Chem., 277, 33338-33343 (2002) 10. Akira Ikari, Yasunobu Suketa: Expression of GFP-tagged low affinity Na+-dependent glucose transporter in xenopus oocytes and CHO cells. Jpn. J. Physiol., 52, 395-398 (2002) 11. Akira Ikari, Tomoko Kano, Yasunobu Suketa: Magnesium influx enhanced by nitric oxide in hypertensive rat proximal tubule cells. Biochim. Biophys. Res. Commun., 294, 710-713 (2002) 12. Toru Kimura, Ayumi Yoshida, Yoshiaki Tabuchi, Akira Ikari, Noriaki Takeguchi, Shinji Asano: Stable expression of gastric proton pump activity at the cell surfacee. J. Biochem., 131, 923-932 (2002) 13. Hideki Sakai, Takahiro Shimizu, Katsuhito Hori, Akira Ikari, Shinji Asano, Noriaki Takeguchi: Molecular and pharmacological properties of inwardly rectifying K+ channels of human lung cancer cells. Eup. J. Pharmacol., 435, 125-133, (2002) 14. Kazuya Kawano, Akira Ikari, Yasunobu Suketa: Phosphatidylinositol 3-kinase mediates inhibitory effect of angiotensin II on sodium/glucose cotransporter in renal epithelial cells. Life Sciences, 71, 1-13, (2002) 2003年 1. Yoshinari K. Kobayashi K. Moore R. Kawamoto T. Negishi M: Identification of the nuclear receptor CAR:HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbital. FEBS Letters. 548(1-3):17-20 (2003) 2. Akira Ikari, Mika Nakano, Mihoko Ishibashi, Kazuya Kawano, Yasunobu Suketa, Hitoshi Harada, Kuniaki Takagi: Recovery from heat shock injury by activation of Na+-glucose cotransporter in renal epithelial cells. Biochim. Biophys. Acta, 1643, 47-53 (2003) 3. Akira Ikari, Kumiko Nakajima, Hitoshi Harada, Kuniaki Takagi: Arachidonic acid-activated Na+- dependent Mg2+ efflux in rat renal epithelial cells. Biochim. Biophys. Acta, 1618, 1-7 (2003) 4. Hideki Sakai, Yuta Ohira, Akiko Tanaka, Tomoyuki Suzuki, Akira Ikari, Magotoshi Morii, Noriaki Takeguchi: Inhibition of small-conductance Cl- channels by the interleukin-1β-stimulated production of superoxide in rabbit gastric parietal cells. J. Physiol. (London), 551, 207-217 (2003) 5. Chan Choo Yap, Fengyi Liang, Yasuhiro Yamazaki, Yuko Muto, Haruo Kishida, Tsuyako Hayashida, Tsutomu Hashikawa, and Ryoji Yano : CIP98, a novel PDZ domain protein, is expressed in the central nervous system and interacts with calmodulin-dependent serine kinase. J Neurochem. 85, 123-134 (2003) 6. Ryoji Yano, Chan Choo Yap, Yasuhiro Yamazaki, Yuko Muto, Haruo Kishida, Daisuke Okada, and Tsutomu Hashikawa : SAST124, a nevel splice variant of syntrophin-associated serine/threonine kinase (SAST), is specifically localized in the restricted brain regions. Neurosci. 117,373-381 (2003) 2004年 1. Junko Sugatani, Nana Fukazawa, Kenji Ujihara, Kouichi Yoshinari, Ikuo Abe, Hiroshi Noguchi, Masao Miwa: Tea polyphenols inhibit acetyl-CoA:1-alkyl-sn-glycero-3- phosphocholine acetyltransferase (a key enzyme in PAF biosynthesis) and PAF- induced platelet aggregation. Intern. Arch. Allergy Immunol., 134, 17-28 (2004) [IF 2.20, Citation 4] 2. Kouichi Yoshinari, Takeshi Sato, Nao Okino, Junko Sugatani, and Masao Miwa: Expression and Induction of Cytochromes P450 in Rat White Adipose Tissue. J. Pharmacol. Exp Ther., 311, 147-154 (2004) [IF 4.098, Citation 7] 3. Junko Sugatani, Kasumi Yamakawa, Eri Tonda, Shinichi Nishitani, Kouichi Yoshinari, Masakuni Degawa, Ikuro Abe, Hiroshi Noguchi, Masao Miwa: The induction of human bilirubin UDP-glucuronosyltransferase mediated through a distal enhancer module by flavonoids and xenobiotics. Biochem. Palmacol., 67(5), 989-1000 (2004) [IF 3.617, Citation 30] 4. Akira Ikari, Naho Hirai, Morihiko Shiroma, Hitoshi Harada, Hideki Sakai, Hisayoshi Hayashi, Yuichi Suzuki, Masakuni Degawa, Kuniaki Takagi: Association of paracellin-1 with ZO-1 augments the reabsorption of divalent cations in renal epithelial cells. J. Biol. Chem., 279, 54826-54832 (2004) 5. Akira Ikari, Kumiko Nakajima, Yasunobu Suketa, Hitoshi Harada, Kuniaki Takagi: Activation of Na+-independent Mg2+ efflux by 20-hydroxyeicosatetraenoic acid in rat renal epithelial cells. Jpn. J. Physiol., 54, 415-419 (2004) 6. Makoto Kaneda, Katsuyoshi Ishii, Yosuke Morishima, Takumi Akagi, Yasuhiro Yamazaki, Shigetada Nakanishi, and Tsutomu Hashikawa : Off-cholinergic-pathway-selective localization of P2X2 purinoceptors in the mouse retina. J. Comp. Neurol. 476, 103-111 (2004) 2005年 1. Takaomi Minami, Hiroyuki Suzuki, Takashi Takeuchi, Shigeru Uemura, Junko Sugatani, Norishige Yoshikawa: A polymorphism in plasma platelet-activating factor acetylhydrolase is involved in resistance to immunoglobulin treatment in Kawasaki disease. J. Pediatr., 147 (1), 78-83 (2005) [IF 3.857, Citation 4] 2. Tadashi Wada, Junko Sugatani, Etsuko Terada, Masao Ohguchi, Masao Miwa: Physico-chemical characterization and biological effects of inulin enzymatically synthesized from sucrose. J. Agric. Food. Chem., 53, 1246-1253 (2005) [IF 2.507, Citation 3] 3. Junko Sugatani, Shinichi Nishitani, Kasumi Yamakawa, Kouichi Yoshinari, Tatsuya Sueyoshi, Masahiko Negishi, Masao Miwa: Transcriptional regulation of human UGT1A1 gene expression: Activated GR enhances CAR/PXR-mediated UGT1A1 regulation with GRIP1 Mol. Pharmacol., 67 (3), 845-855 (2005) [IF 4.612, Citation 18] 4. Mitsutoshi Tukimoto, Hitoshi Harada, Akira Ikari and Kuniaki Takagi: Involvement of chloride in apoptotic cell death induced by activation of ATP-sensitive P2X7 purinoceptor. J. Biol. Chem., 280, 2653-2658 (2005) [IF 5.854] 5. Akira Ikari, Mika Nakano, Yasunobu Suketa, Hitoshi Harada and Kuniaki Takagi: Reorganization of ZO-1 by sodium-dependent glucose transporter activation after heat stress in LLC-PK1 cells. J. Cell. Physiol., 203, 471-478 (2005) 6. Akira Ikari, Hitoshi Harada and Kuniaki Takagi: Role of actin in the cAMP-dependent activation of sodium/glucose cotransporter in renal epithelial cells. Biochim. Biophys. Acta., 1711, 20-24 (2005) [IF 2.751] 7. Kuniaki Takagi, Tsuyoshi Hasunuma, Nobuhiro Goi, Hitoshi Harada, Akira Ikari, Mitsuo Hiramatsu, Kimitsugu Nakamura and Hirohito Tsuboi: The effects of performance anxiety on salivary ultra-weak chemiluminescence. Stress and Health, 21, 263-268 (2005) 8. Akira Ikari, Yoshiaki Nagatani, Mitsutoshi Tsukimoto, Hitoshi Harada, Masao Miwa and Kuniaki Takagi: Sodium-dependent glucose transporter reduces peroxynitrite and cell injury caused by cisplatin in renal tubular epithelial cells. Biochim. Biophys. Acta., 1717, 109-117 (2005) [IF 2.751] 9. Akira Ikari, Hitoshi, Harada, Kuniaki Takagi, Masakuni Degawa, Masao Miwa: Localization of claudin-16 in tight functionand transport of divalent cations. Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan, 125, 116-117 (2005) 10. Benjamin Delprat, Vincent Michel, Richard Goodyear, Yasuhiro Yamazaki, Nicolas Michalski, Aziz El-Amraoui, Isabelle Perfettini, Pierre Legrain, Guy Richardson, Jean-Pierre Hardelin and Christine Petit: Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly. Hum. Mol. Genet. 14, 401-410 (2005) 11. J. Sugatani, T. Sueyoshi, M. Negishi, M. Miwa: Regulation of the human UGT1A1 gene by nuclear receptors CAR, PXR and GR. In “Conjugation Enzymes”. (H. Sies, and L. Packer, eds.) Methods in Enzymology, Elsevier Inc., 92-104 (2005) 2006年 1. Kouichi Yoshinari, Shunsuke Takagi, Junko Sugatani, Masao Miwa: Changes in the expression of cytochrome P450 and nuclear receptors in the liver of genetically diabetic db/db mice. Biol. Pharm. Bull., 29, 1634-1638 (2006) [IF 1.317, Citation 1] 2. Naoki Unno, Takanori Sakaguchi, Toshio Nakamura, Naoto Yamamoto, Junko Sugatani, Masao Miwa, Hiroyuki Konno: A single nucleotide polymorphism in the plasma PAF acetylhydrolase gene and risk of atherosclerosis in Japanese patients with peripheral artery occlusive disease. J. Surg. Res., 134(1), 36-43 (2006) [IF 1.956] 3. Kouichi Yoshinari, Nao Okino, Takeshi Sato, Junko Sugatani, Masao Miwa: Induction of detoxifying enzymes in rodent white adipose tissue by aryl hydrocarbon receptor agonists and antioxidants. Drug Metab. Dispos., 34(7), 1081-1089 (2006) [IF 4.015] 4. Kouichi Yoshinari, Shunsuke Takagi, Junko Sugatani, Masao Miwa: Hepatic CYP3A expression is attenuated in obese mice fed a high-fat diet. Pharm. Res., 23(6), 1188-1200 (2006) [IF 2.752, Citation 1] 5. Junko Sugatani, Tadashi Wada, Makoto Osabe, Kasumi Yamakawa, Kouichi Yoshinari, Masao Miwa: Dietary inulin alleviates hepatic steatosis and xenobiotics-induced liver injury in rats fed a high-fat and high-sucrose diet: Association with the suppression of hepatic cytochrome P450 and HNF4α expression. Drug Metab. Dispos., 34(10), 1677-1687 (2006) [IF 4.015] 6. Akira Ikari., Satomi Matsumoto, Hitoshi Harada, Kuniaki Takagi, Masakuni Degawa, Tadanobu Takahashi, Junko Sugatani, Masao Miwa: Dysfunction of paracellin-1 by dephosphorylation in Dahl salt-sensitive hypertensive rats. J. Physiol. Sci., 56, 379-383 (2006) [IF 1.760] 7. Akira Ikari., Satomi Matsumoto, Hitoshi Harada, Kuniaki Takagi, Hisayoshi Hayashi, Yuichi Suzuki, Masakuni Degawa, Masao Miwa: Phosphorylation of paracellin-1 at serine 217 by protein kinase A is essential for localization in tight junction. J. Cell Sci., 119, 1781-1789 (2006) 8. Mitsutoshi Tsukimoto, Machiko Maehata, Hitoshi Harada, Akira Ikari, Kuniaki Takagi, Masakuni Degawa: P2X7 receptor-dependent cell death is modulated during murine T cell maturation and mediated by dual signaling pathways. J. Immunol., 177, 2842-2850 (2006) [IF 6.387] 9. Chao-Tan Guo, Tadanobu Takahashi, Kazuya I.P.J. Hidari, Daisei Miyamoto, Takashi Suzuki, Yasuo Suzuki: Edible bird’s nest extraction inhibits the influenza virus infection. Antiviral Res., 70, 140-146 (2006) 10. Toshihiro Kogure, Takashi Suzuki, Tadanobu Takahashi, Daisei Miyamoto, Kazuya I.P.J. Hidari, Chao-Tan Guo, Toshihiro Ito, Yoshihiro Kawaoka, Yasuo Suzuki: Human trachea primary epithelial cells express both sialyl-2,3 Gal receptor for human parainfluenza virus type 1 and avian influenza viruses, and sialyl-2,6 Gal receptor for human influenza viruses. Glycoconj. J., 23, 101-106 (2006) 11. Chie Aoki, Kazuya I.P.J. Hidari, Saki Itonori, Akihiro Yamada, Naonori Takahashi, Takeshi Kasama, Futoshi Hasebe, Mohammend Alimul Islam, Ken Hatano, Koji Matsuoka, Takao Taki, Chao-Tan Guo, Tadanobu Takahashi, Yuichi Sakano, Takashi Suzuki, Daisei Miyamoto, Mutsumi Sugita, Daiyo Terunuma, Koichi Morita, Yasuo Suzuki: Identification and characterization of carbohydrate molecules in mammalian cells recognized by dengue virus type 2. J. Biochem. (Tokyo), 139, 607-614 (2006) [IF 3.638] 12. Yasuko Nagatsuka, Yasuhiro Horibata, Yasuhiro Yamazaki, Masami Kinoshita, Yoko Sinoda, Tsutomu Hashikawa, Hiroyuki Koshino, Takemichi Nakamura, and Yoshio Hirabayashi : Phosphatidylglucoside exists as a single molecular species with saturated fatty acyl chains in developing astroglial membranes. Biochemistry 45, 8742-8750 (2006) 13. Yasuhiro Yamazaki, Yasuko Nagatsuka, Eriko Oshima, Yasuo Suzuki, Yoshio Hirabayashi, and Tsutomu Hashikawa : Comprehensive analysis of monoclonal antibodies against detergent-insoluble membrane/lipid rafts of HL60 cells. J Immunol. Methods 311, 106-116 (2006) 2007年 1. A. Ikari, M. Ito, C. Okude, H. Sawada, H. Harada, M. Degawa, H. Sakai, T. Takahashi, J. Sugatani, M. Miwa: Claudin-16 is directly phosphorylated by protein kinase a independently of a vasodilator-stimulated phosphoprotein-mmediated pathway. J. Cell Physiol., 214, 221-229 (2007) [IF 3.638] 2. A, Ikari, C. Okude, H. Sawada, T. Takahashi, J. Sugatani, M. Miwa: Down-regulation of TRPM6-mediated magnesium influx by cyclosporine A. Arch. Pharmacol., in press. [IF 2.779] 3. M. Osabe, J. Sugatani, T. Fukuyama, S. Ikushiro, A. Ikari, M. Miwa: Constitutive androstane receptor and peroxisome proliferator-activated receptor a are activated in liver of male rats fed a high-fat and high-sucrose diet and the hepatic expression of UGT1A1 and UGT1A6 is enhanced. Drug Metab. Dispos., in press . [IF 4.015] 4, Nobuhiro Goi, Yuko Hirai, Hitoshi Harada, Akira Ikari, Takahiko Ono, Naohide Kinae, Mitsuo Hiramatsu, Kimitsugu Nakamura, Kuniaki Takagi: Comparison of peroxidase response to metal arithmetic stress in saliva of smokers and non-smokers. J. Toxicol. Sci., 32, 121-127 (2007) 5. Yasuhiro Yamazaki, Yasuhiro Horibata, Yasuko Nagatsuka, Yoshio Hirabayashi, and Tsutomu Hashikawa : Fucoganglioside a-fucosyl(a-galactosyl)-GM1: a novel member of lipid membrane microdomain components involved in PC12 cell neuritogenesis. Biochem. J, 407, 31-40 (2007) 6. 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