Synergy report example - Chalice Analyzer Online

Chalice Synergy Report
[email protected] - 03 Jun 2014
Combination: Compound A x Compound B
Measure: Inhibition
99
44
61
69
69
76
73
88
97
6
34
34
48
58
66
74
87
0
20
31
35
46
53
65
79
0
1
21
26
47
50
66
77
0
5e-3
.01
.02
.05
.1
.2
.5
.1
.05
79
79
79
79
66
66
68
68
70
72
74
75
40
45
48
52
60
66
71
74
10
21
27
37
51
62
68
73
3
13
21
32
48
59
67
73
0
8
15
26
44
57
66
73
0
5e-3
.01
.02
.05
.1
.2
.5
Compound B (uM)
0 1e-3
.01
.1
1
Compound B (uM)
Dose Response Chart | [email protected] |
50
100
1
Inhibition
.5
Compound B / .5uM
15
16
14
15
15
18
-4
4
6
10
13
16
18
21
-2
10
11
14
16
18
19
24
4
16
21
17
16
7
17
23
-4
13
7
11
7
4
6
14
-3
7
10
3
-2
-6
-2
6
0
-7
6
0
3
-7
0
4
0
5e-3
.01
.02
.05
.1
.2
.5
2.96
0
0
14
12
Synergy Score
0
Inhibition
Dose Response Chart | [email protected] |
.5
0
Compound A / 1.2uM
1
Additivity
Inhibition=80.0
Isobologram | [email protected] |
14
9
Compound B (uM)
50
100
Compound B (uM)
12
9
0 .01
.1
1
10
Compound A (uM)
Created with Chalice Analyzer Online - http://cwr.horizondiscovery.com/
Chi2=1e-20
93
79
10
1
Inhibition Vol=5.76
90
79
5
86
79
9
2
82
78
2
1
79
82
.5
76
82
.25
.5
64
83
82
.1
100
83
82
0
97
83
82
Compound A (uM)
95
83
82
N=1
92
83
82
Loewe Excess | [email protected] |
Inhibition
89
5
85
83
2
83
83
82
1
1
74
83
.5
2
100
.25
99
97
.1
98
97
.05
97
96
0
97
94
Loewe Model | [email protected] |
Compound A (uM)
95
91
N=1
93
91
Inhibition
5
92
83
.25
85
0
Compound A (uM)
Dose Matrix | [email protected] |
.05
Created at Horizon CombinatoRx with Chalice Analyzer