Thomas Knoll, MD PhD MSc Associate Professor of Urology Department of Urology Sindelfingen-‐Boeblingen Medical Center University of Tuebingen 71065 Sindelfingen, Germany +49 7031 9812501 t.knoll@klinikverbund-‐suedwest.de Birth date: Place of birth: June 12, 1971 Eberbach, Germany Spouse: Children: Maria Antonia Knoll, MD Lale Marie Knoll Felix Nepomuk Knoll Mats Jakob Knoll Education and Training 10/1992-‐10/1998 11/1998-‐12/1999 01/2000-‐12/2002 01/2003-‐12/2003 01/2004-‐05/2004 06/2004-‐08/2004 09/2004-‐12/2004 10/2011-‐12/2011 Medical School, University of Heidelberg, Germany Intern and Resident in Nephrology and Rheumatology Mannheim University Hospital, Germany Resident in Urology Mannheim University Hospital Resident in General Surgery, Mannheim University Hospital Resident in Urology, Mannheim University Hospital Fellow in Endourology and Uro-‐oncology, Capa University Hospital, Istanbul, Turkey Resident in Urology, Mannheim University Hospital Training in robotic surgery, Recklinghausen, Ruhr University, Bochum Certification and Academic Titles 11/1998 2000 06/2005 09/2006 2011 MD-‐Thesis “Role of selective Endothelin-‐1-‐Receptor Anatagonism in acute postischemic renal failure of the rat”, University of Heidelberg German Board of Medicine PhD-‐Thesis “Calciumoxalate Stone Formation: New concepts for Pathogenesis, Therapy and Prevention”, University of Heidelberg MSc-‐Thesis Healthcare Management “Economic Aspects of Outpatient Surgery in Urology”, University of Mannheim Kuwait Board of Medicine Academic and Clinical Appointments Academic Appointments 01/2004-‐12/2004 01/2005-‐11/2007 Instructor in Urology, Mannheim University Hospital Medical School Assistant Professor in Urology, Mannheim University Thomas Knoll, MD PhD MSc 12/2007-‐present 08/2008-‐present Hospital Medical School Associate Professor in Urology, Mannheim University Hospital Medical School Lecturer in Urology, University of Tuebingen Medical School, Germany Clinical Appointments 04/2004-‐07/2008 01/2005-‐07/2008 08/2008-‐present Research Interests Head of Minimal-‐invasive Urology, Mannheim University Hospital Staff Physician, Mannheim University Hospital Head of Urology, Sindelfingen-‐Boeblingen Medical Center, University of Tuebingen, Germany 1. Genetic pathomechanisms and potential therapeutic options of cystinuria 2. Evaluation and Development of new minimal-‐invasive techniques and instruments: -‐ Urinary stone disease (Mini-‐PCNL, flexible URS, SWL) -‐ Benign prostatic hyperplasia (application of medical lasers) -‐ Laparoscopy (application of 3D-‐imaging) -‐ Superficial bladder cancer (Photodynamic imaging and laser application) 3. Development of preventive approaches for recurrent calcium oxalate stone formation 4. Development and evaluation of medical simulators and training tools 5. Experimental research on treatment options of chronic renal transplant failure Grant support – – – – – Richard Wolf Foundation, “Impact on photodynamic imaging on the recurrence of superficial bladder cancer”, 01/2006-‐12/2008, €50.000 Richard Wolf Foundation, “Endoscopic superficial laser ablation of renal papillas”, 01/2004-‐01/2006, €50.000 Research Fund, University of Heidelberg, “Experimental research on cystinuria”, 01/2004-‐12/2004, €25.000 Research Fund, University of Heidelberg, “Laser application for gene transfer”, 01/2002-‐12/2002, €25.000 German Research Foundation (DFG), “Treatment of chronic renal transplant failure”, 01/1997-‐12/1999, €60.000 Honors and Awards 1997 2000 2002 2004 2005 2005-‐2007 20/06/14 DFG Research Grant “Chronic renal allograft failure” Poster Award, German Society of Urology Best Poster, Southwestern German Society of Urology Best Abstract in Stone Disease, American Urological Association Wolfgang-‐Hepp-‐Award, German Society of Urology Award for best lectures, Mannheim University Medical School 2 Thomas Knoll, MD PhD MSc 2005 2005 2011 2013 Young Investigator Award, European Urolithiasis Society 2nd Best Experimental Abstract, European Association of Urology Poster Award, European Association of Urology Arthur-‐Smith-‐Lectureship Award, Endourology Society Membership in Professional Societies 2000-‐present 2000-‐present 2001-‐present 2001-‐present 2002-‐present 2004-‐present 2004-‐present 2004-‐present 2004-‐present 2005-‐2007 2005-‐present 2006-‐present 2011-‐2012 2011-‐2012 2011-‐present German Society of Urology (DGU) European Association of Urology (EAU) Endourology Society Southwestern German Society of Urology German Society for Ultrasound in Medicine (DEGUM) German Working Group Urolithiasis EAU Guideline Group on Urolithiasis Erich-‐Frank-‐Society for German-‐Turkish Relationships in Medicine European Intrarenal Surgery Society (EIRSS) AUA-‐EAU Collaborative Guideline Group on Ureteric Stones German Society for Shock Wave Lithotripsy (DGSWK) American Urological Association (AUA) EAU Young Academic Urologists Group German Working Group Robotics, Laparoscopy and Endourology International Cooperation in Endourology (ICE) Editorial Positions, Boards, and Peer-‐Review Service Guest Editor 2010 2011 Boards 2002-‐2003 2007-‐present 2008-‐present 2008-‐present 2009-‐present 2009-‐present 2010-‐present 2010-‐present 2010-‐present 2011-‐present 2011-‐present 2013-‐present 2012-‐present European Urology Supplement, Vol. 9 World Journal of Urology, Vol. 29 Program Committee German Society of Urology (DGU) EAU Section for Urolithiasis (ESUT) Vice-‐Chair EAU Guideline Group on Urolithiasis Chair German Working Group on Urolithiasis German Society for Shock Wave Lithotripsy Urological Research Video-‐Urology Journal, Journal of Endourology Educational Board, Southwestern German Board of Medicine Vice-‐Chair EAU Section for Uro-‐Technology (EULIS) International Collaboration in Endourology (ICE) Section Editor, World Journal of Urology Journal of Endourology EAU Panel on Ethics in Live Surgery Peer-‐Review Service 2003-‐present German Society of Urology (DGU) 2004-‐present Urological Research 2005 Israel Science Foundation 2005-‐present Journal of Endourology 2005-‐present European Association of Urology (EAU) 20/06/14 3 Thomas Knoll, MD PhD MSc 2005-‐present 2005-‐present 2007-‐present 2008-‐present 2010-‐present 2012 European Urology Urologe Journal of Urology Urologia Internationals World Journal of Urology University of British Columbia, Vancouver, Canada Teaching Dissertation Committees 1999-‐2005 Doctoral Committee for Jens Oltersdorf 1999-‐2003 Doctoral Committee for Uwe Göttmann 2000-‐2003 Doctoral Committee for Hans Sobek 2003-‐2007 Doctoral Committee for Sreedhar Sagi 2004-‐2006 Doctoral Committee for Yanwei Cao 2004-‐2005 Doctoral Committee for Mahmoud Osman 2004-‐2007 Doctoral Committee for Katrin Heger 2005-‐2007 Doctoral Committee for Kristina Dobler 2006-‐2009 Doctoral Committee for Patrick Krombach 2006-‐2008 Doctoral Committee for Yvonne Alfano 2006-‐2009 Doctoral Committee for Thomas Zimmerer 2007-‐2009 Doctoral Committee for Kristina Richardt 2006-‐2010 Doctoral Committee for Susanne Christmann 2009-‐present Doctoral Committee for Heiko Kohns 2011-‐present Doctoral Committee for Martina Holten 2012-‐present Doctoral Committee for Thorsten Brantes 2012-‐present Doctoral Committee for Michael Berner Research Mentor/Supervisor Postdoctoral Fellows 2002-‐2010 Gunnar Wendt-‐Nordahl, MD 2003-‐2010 Patrick Honeck, MD 2010-‐present Jan Peter Jessen, MD 2011-‐present David Zimmermann, MD Consulting Positions 2002-‐2005 2002-‐present 2011-‐present 2011-‐present 2011-‐present 2011-‐present 2013-‐present Simbionix Simulators Karl Storz Endoscopes Schoelly Endoscopes Coloplast Boston Scientific Storz Medical Olympus Visiting Professorships 11/2007 11/2007 10/2010 20/06/14 Harbin University Medical School, China Jinan University Medical School, China Academic Stone Center, Kunming Medical School, China 4 Thomas Knoll, MD PhD MSc 04/2012 03/2013-‐present Chilean Society of Urology, Santiago, Chile Guangzhou Medical School, Guangzhou, China Extramural Invited Presentations and Moderations 2003 2003 2004 2004 2005 2005 2005 2005 2006 2006 2006 2006 2006 2006 2007 2007 2007 2007 2007 2008 2008 2008 2008 2008 2008 20/06/14 “Percutaneous Nephrolithotomy”, Klinikum Coburg, Germany “Percutaneous Nephrolithotomy”, Annual Meeting of the European Intrarenal Surgery Society, Edinburgh, UK Moderation “Urolithiasis and Andrology”, DGU Annual Meeting, Germany “Current standards in stone therapy”, Military Hospital, Ulm, Germany Moderation “Urolithiasis, Andrology and Urogynecology”, Fulda, Germany Endourology and Laparoscopy Session, AUA Annual Meeting, San Antonio, TX “Update Ureteroscopy”, Northern German Urology Meeting, Kiel, Germany Moderation “Experimental Urolithiasis Session”, DGU Annual Meeting, Wiesbaden, Germany “Costs and Reimbursement” Session, “What’s new in Urology Session”, “Pathogenesis of calciumoxalate stone formation”, Annual Meeting SWDGU, Frankfurt, Germany “Ureteroscopy”, Swedish Society of Urology, Stockholm, Sweden “Update flexible Ureteroscopy”, Hellenic Society of Urology, Geneva, Switzerland Moderation Urolithiasis Session, DGU Annual Meeting, Hamburg, Germany “Endourology in difficult anatomy”, “Therapy of bilateral stones”, Urolithiasis Sympsium, Dresden, Germany 23rd Urology Course for nurses and medical assistants, Mannheim, Germany Moderation Urolithiasis Session, “Percutaneous Nephrolithotomy”, EAU Annual, Meeting, Berlin, Germany Urolithiasis Session, “Ureteroscopy”, Annual Meeting DGSWL, Saarbruecken, Germany “Current standards in urolithiasis”, Klinikum Fulda, Germany Urolithiasis Session, Berlin, Germany “The renal papilla and calcium oxalate stone formation”, Annual Meeting of the C. E. Alken Society, Stuttgart, Germany Uro-‐Oncology Working Group, Bonn-‐Siegburg, Germany “Interventional Therapy of Urinary Stones”, Urolithiasis Session, EAU Annual Meeting, Milan, Italy “Perspectives on Side Effects of ESWL”, Indiana University of Medicine, Indianapolis, IN Skills Assessment and Surgical Training Session, AUA Annual Meeting, Orlando, FL “Update Urolithiasis”, Eastern German Urology Meeting, Weimar, Germany “Treatment concepts for Urolithiasis”, Cologne Urology Days, 5 Thomas Knoll, MD PhD MSc 2009 2009 2009 2009 2009 2009 2009 2009 2009 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2011 2011 2011 20/06/14 Cologne, Germany Moderation Research and Medical Treatment of Urolithiasis Session, EAU Annual Meeting Stockholm, Sweden Safety and efficacy of treatments for stones, EAU Annual Meeting, Stockholm, Sweden “New Guidelines Urolithiasis”, Eastern German Urology Meeting, Chemnitz, Germany “Guidelines Urolithiasis”, Bavarian-‐Austrian Urology Meeting, Salzburg, Austria “Treatment of Large Stones”, 1st Meeting of the EAU Section Urolithiasis (EULIS), London, UK Moderation “Sparing the Nephron in Kidney Stones”, World Congress of Endourology, Munich, Germany “Lower Pole Stones: Flexible URS”, EULIS Symposium, Como, Italy “Urolithiasis in the Elderly”, Curriculum Urologicum, Berlin, Germany “Percutaneous nephrolithotomy”, Symposium d’Endourologie, Paris, France “Guidelines Urolithiasis”, Urology Forum, Zuers, Austria “Extracorporal shock wave lithotripsy”, Hall i. Tyrol, Austria “Metabolic evaluation and prevention of urolithiasis”, Rheinische Gespräche, Dusseldorf, Germany “Evidence for stone therapy”, Curriculum Urologicum, Stuttgart, Germany “Percutaneous nephrolithotomy – Prone position”, EAU Annual Meeting, Barcelona, Spain “Current treatment concepts for Urolithiasis”, Kunming, China “Prostate cancer – Update on diagnostics”, Satellite Symposium, AUA Annual Meeting, San Francisco, CA “Guidelines on Urolithiasis”, Northern German Urology Meeting, Potsdam, Germany “How far should live surgery go?”, World Congress on Endourology, Chicago, IL Moderation “Ureteral physiology/Laparoscopy II”, World Congress on Endourology, Chicago, IL Point-‐Counterpoint-‐Discussion “Lower pole stones”, DGU Annual Meeting, Dusseldorf, Germany “Lower Pole Stones: Flexible URS”, Moderation “PNL and URS Session”, EULIS Symposium, Como, Italy “Guidelines on Urolithiasis”, Military Hospital Koblenz, Germany “Flexible URS for large renal calculi”, Panhellenic Urology Meeting, Larncaca, Cyprus “Current update on Urolithiasis”, Salzhaeuser Gespraeche, Lueneburg, Germany “Congress Souvenirs Urolithiasis and BPH”, Klinikum Altona, Hamburg, Germany “Update Urolithiasis”, Urology Forum, Zuers, Austria “Laser Prostatectomy: Thulium Laser”, ESUT Expert Meeting, Davos, Switzerland “Mini-‐PNL”, 2nd World Congress on Controversies in Urology, Paris, 6 Thomas Knoll, MD PhD MSc 2011 2011 2011 2011 2011 2011 2011 2011 2011 2011 2012 2012 2012 2012 2012 2012 2012 2012 2012 2012 2012 2012 2012 2012 2012 2012 20/06/14 France “How to treat stones in 2011”, University Hospital, Kiel, Germany Moderation Urolithiasis Session, SWDGU Annual Meeting, Tuebingen, Germany “Rigid and flexible Ureteroscopy”, 2nd Comprehensive Urolithiasis Workshop, Sofia, Bulgaria “Stones and renal cancer”, Urolithiasis Course, Glashuette, Germany “Diagnostics and intervention for urinary calculi”, Bremen, Germany “Auditing and Quality Control in Laparoscopy and Endourology”, AUA Annual Meeting (E&U Session), Washington, USA “Challenges in BPH treatment” Session, Challenges in Endourology, Paris, France “Dilatation for percutaneous surgery”, “Tailored treatment concepts for BPH”, Round-‐table discussion “BPH Treatment”, World Congress on Videourology, Torino, Italy “Metabolic evaluation and prevention of urinary stones”, Urolithiasis Course, Bremen, Germany “Cystinuria”, Istanbul Urolithiasis Days, Istanbul, Turkey Moderation Live Surgery: Navigation and More, EAU Annual Meeting, Paris, France Moderation Challenges in Education/Urolithiasis, EAU Annual Meeting, Paris, France Round Table Discussion “Stone Disease”, EAU Annual Meeting, Paris, France Retrograde Intrarenal Surgery for Stone Therapie, EAU Annual Meeting, Paris, France Moderation Personalized Treatment of Urinary Stone disease”, EAU Annual Meeting, Paris, France “Mini PCNL”, Masterclass Urolithiasis, Amsterdam, The Netherlands “What’s new in Urolithiasis”, Urology Meeting, Datteln, Germany “Future Techniques in Urology”, “Guidelines Urolithiasis”, Doelln Urology Meeting, Germany “Mini-‐PNL”, “PNL: Prone Position”, “Stones in the Lower Pole”, International Meeting on Urolithiasis, Ouro Preto, Brazil “Where are we apart from Da Vinci: Current state of 3D laparoscopy”, AUA Annual Meeting (E&U Session), Atlanta, GE “Evidence for Stone Therapy”, “Update Ureteroscopy”, “Update Percutaneous Nephrolithotomy”, Urolithiasis Course, Chilean Society of Urology, Santiago, Chile “Ureteroscopy and Stenting”, Annual Meeting of the British Association of Urology (BAUS), Glasgow, UK “EAU and AUA Souvenirs: Oncology and Robotics”, Petersberg Summer Symposia, Petersberg, Germany “PNL: Less Complications, better Efficacy”, World Congress of Endourology, Istanbul, Turkey Moderation “Urolithiasis/Epidemiology”, World Congress of Endourology, Istanbul, Turkey Round Table: Complications of Endourology: Prevention and Management, World Congress of Endourology, Istanbul, Turkey 7 Thomas Knoll, MD PhD MSc 2012 2012 2012 2012 2012 2012 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 20/06/14 “Mini PNL: Yes or No?”, Endourology Meeting, Torino, Italy “Thulium Laser Prostatectomy”, “Medical Treatment of BPH”, Fall Urology Course, Recklinghausen, Germany “Flexible Ureteroscopy”, 6th International Conference of the Royal Medical Services, Dead Sea, Jordan “Urolithiasis in children – Diagnosis, Therapy, Prevention”, Curriculum Urologicum , Hamburg, Germany “Extracorporal Shock Wave Lithotripsy”, Masterclass Urolithiasis, Amsterdam, The Netherlands “Refining Indications for PNL”, Experts in Stone Disease, Dubai, VAE Generation Y – Challenges in recruiting residents and fellows, Urology Forum, Zuers, Austria “What is new in Urolithiasis”, UroUpdate, Duesseldorf, Germany “En-‐bloc Thulium Laser Resection of Non-‐Muscle Invasive Bladder Cancer”, Expert meeting on Superficial Bladder Cancer, Davos, Switzerland “Percutaneous stone manipulation”, Tips & Tricks in Endourology, EAU Wintermeeting Challenge the Expert, Davos, Switzerland “Urolithiasis”, Uro Update, Dusseldorf, Germany “Observation and deferred treatment for urinary stones”, EAU Annual Meeting, Milan, Italy “Stone analysis and epidemiology of urinary stone disease”, EAU Annual Meeting, Milan, Italy “A new perspective in the management of urolithiasis”, Xpanse meeting, Shenzhen, China “Surgical management of BPH”, Xpanse meeting, Shenzhen, China “Mini-‐PNL: How I do it”, Annual meeting of the Turkish society for endourology, Antalya, Turkey “Mini PNL is superior”, Annual meeting of the Turkish society for endourology, Antalya, Turkey “Are the indications for PNL decreasing?”, Annual meeting of the Turkish society for endourology, Antalya, Turkey “The difficult stone case”, Panel discussion, Annual meeting of the Turkish society for endourology, Antalya, Turkey Update Urolithiasis, Urological Academy Spring meeting, Heidelberg, Germany “ESWL update”, Summer Meeting, German Urology Association (BDU), Sylt, Germany “Modern Working time models – Generation Y”, Annual Meeting of the South Western Society of Urology, Baden-‐Baden, Germany “Therapeutic options in CRPC prior chemotherapy”, Annual Meeting of the South Western Society of Urology, Baden-‐Baden, Germany “Metabolics in Stone Disease”, 3rd Challenges in Endourology, Paris, France “Update percutaneous nephrolithotomy”, Postgraduate Course Urology, Lisbon, Portugal “Diversity in Urolithiasis”, 2nd EULIS meeting, Copenhagen, Denmark “Conservative treatment of urinary calculi”, Annual Meeting of the German Society of Urology, Dresden, Germany What is new in percutaneous surgery?, 2nd Meeting of the International Alliance in Urology, Nanning, China 8 Thomas Knoll, MD PhD MSc 2013 2013 2013 2013 2014 2014 2014 2014 2014 2014 2014 2014 2014 2014 2014 2014 2014 2014 2014 Miniaturization of PNL – Potential advantages and limitations, Urolithiasis Meeting, Guangzhou University, China Update Urolithiasis, Fall Seminar, Recklinghausen, Germany TUR-‐Prostate: Intraoperative Techniques, TUR-‐Prostate Course of the German Working Group on Endourolgy, Heilbronn, Germany Thulium Laser Enucleation of the Prostate, BPH Meeting, Ahmedabad, India Flexible URS: Indications, Technique, Tips and tricks, Urology Winter Meeting, Vaasa, Finland “Update Cystectomy”, Workshop Bladder cancer, 3iPathways, Berlin, Germany “Update Neoadjuvant and Adjuvant Chemotherapy”, Workshop Bladder cancer, 3iPathways, Berlin, Germany “Mini-‐, Ultra-‐Mini-‐, Mikro-‐PNL”, 1st Meeting of the German Urolithiasis Working Group, Hamburg, Germany Challenge the Guidelines: RIRS vs. ESWL for lower pole stones, EAU Annual Meeting, Stockholm, Sweden Multi-‐tract PNL, EULIS Section Meeting, EAU Annual Meeting, Stockholm, Sweden ESU Course “Percutaneous nephrolithotomy”, EAU Annual Meeting, Stockholm, Sweden “Emerging Techniques: Tubeless, Mini, Micro PNL”, Update Urolithiasis, Kuwait “Prone, Supine, Endoscopic Combined PNL”, Update Urolithiasis, Kuwait “Update imaging modalities for bladder cancer”, Athens Urology Days, Athens, Greece “How I treat lower pole stones”, Athens Urology Days, Athens, Greece “Update Urolithiasis”, Spring Forum of the German Acadamy of Urology, Dresden, Germany New technology in Laparoscopy and Endourology, Engineering & Urology, Annual Meeting of the American Urological Association, Orlando, FL, USA “Laparoscopic nephrectomy”, Challenges in Laparoscopy and Robotics, Barcelona, Spain Laparotomy and Lymph node Dissection, Surgical training course for residents, Mannheim, Germany Invitations as a tutor in Laparoscopy, Endourology, and Urolithiasis 2003 2004 2004 2004 2005 2005 2005 2006 20/06/14 Hands-‐on-‐Training URS, EAU Annual Meeting, Madrid, Spain Hands-‐on-‐Training URS, EAU Annual Meeting, Vienna, Austria Hands-‐on-‐Training URS, Annual Meeting Southwestern German Society of Urology (SWDGU), Heidelberg, Germany Hands-‐on-‐Training URS, DGU Annual Meeting, Dusseldorf, Germany Hands-‐on-‐Training URS, DGU Annual Meeting, Wiesbaden, Germany Hands-‐on-‐Training URS, EAU Annual Meeting, Istanbul, Turkey Hands-‐on-‐Training URS, Annual Meeting SWDGU, Fulda, Germany Hands-‐on-‐Training URS, DGU Annual Meeting, Hamburg, Germany 9 Thomas Knoll, MD PhD MSc 2006 2007 2009 2009 2010 2010 2010 2011 2011 2011 2011 2012 2012 2012 2012 2012 2012 2013 2013 2013 2013 2013 2013 2013 2013 2014 2014 2014 2014 2014 Hands-‐on-‐Training URS, Annual Meeting SWDGU, Frankfurt, Germany Hands-‐on-‐Training Laparoscopy, EAU EUREP Meeting, Prague, Czech Republic New Trends in Percutaneous Nephrolithotripsy, World Congress of Endourology, Munich, Germany Annual Refresher Course for Residents in Urology, Stromberg, Germany Hands-‐on-‐Training URS, EAU Annual Meeting, Barcelona, Spain Hands-‐on-‐Training URS, DGU Annual Meeting, Dusseldorf, Germany Hands-‐on-‐Training URS, Northern German Urology Meeting, Potsdam, Germany Hands-‐on-‐Training URS, EAU Annual Meeting, Vienna, Austria Hands-‐on-‐Training URS, DGU Annual Meeting, Hamburg, Germany Prophylaxis and Medical Management of Urolithiasis, World Congress of Endourology, Kyoto, Japan Moderation “BPH, TUR, Female Urology”, World Congress of Endourology, Kyoto, Japan Hands-‐on-‐Training Endourology, European Urology Forum, Davos Hands-‐on-‐Training URS, EAU Annual Meeting, Paris, France Prophylaxis and Medical Management of Urolithiasis, World Congress of Endourology, Istanbul, Turkey Hands-‐on-‐Training URS, DGU Annual Meeting, Leipzig, Germany Hands-‐on-‐Training Laser Prostatectomy, DGU Annual Meeting, Leipzig, Germany Hands-‐on-‐Training PCNL, DGU Annual Meeting, Leipzig, Germany Annual Refresher Course for Residents in Urology, Stromberg, Germany Hands-‐on-‐Training Endourology, European Urology Forum, Davos Hands-‐on-‐Training URS, EAU Annual Meeting, Milan, Italy “Percutaneous nephrolithotomy”, Instruction Course, European School of Urology, EAU Annual Meeting, Milan, Italy “Ureteroscopy school”, Richard-‐Wolf-‐Training Center, Knittlingen, Germany Ureteroscopy Hands-‐on-‐Training, Surgical training course for residents, Mannheim, Germany Ureteroscopy Hands-‐on-‐Training, DGU Annual Meeting, Dresden, Germany TUR-‐Prostate Course of the German Working Group on Endourology, Heilbronn, Germany Hands-‐on-‐Training Endourology, European Urology Forum, Davos Hands-‐on-‐Training URS, EAU Annual Meeting, Stockholm, Sweden E-‐Blus Exam Laparoscopy, EAU Annual Meeting, Stockholm, Sweden Annual Refresher Course for Residents in Urology, Stromberg, Germany Laparoscopy Hands-‐on-‐Training, Surgical training course for residents, Mannheim, Germany Invitations as a surgeon 20/06/14 10 Thomas Knoll, MD PhD MSc 2004 2005 2006 2006 2006 2007 2007 2007 2007 2008 2008 2008 2009 2010 2010 2010 2010 2011 2011 2011 2011 2011 2012 2012 2012 2012 2012 2012 2012 2012 2013 2013 2013 2013 2014 2014 2014 Annual Meeting Jordanian Society of Urology, Amman, Jordan Endourology Workshop, University of Tuebingen, Germany Clinical Refresher Course Urology, Mannheim University Hospital Endourology Workshop, University of Tuebingen, Germany Update Endourology, Mannheim University Hospital Update Endourology, Mannheim University Hospital 5th Workshop on Endourology, Pforzheim, Germany University Hospital Harbin, China University Hospital Jinan, China 2nd Endourology Workshop Barmbeck, Hamburg, Germany 7th Workshop on Endourology, Pforzheim, Germany Endovision, University of Tuebingen, Germany Endovision, Hall Medical Center, University of Innsbruck, Austria Academic Stone Center, University Hospital Kunming, China Symposium d’Endourologie, Paris, France Surgical Urology Meeting, Mannheim University Hospital, Germany Urolithiasis Workshop, Dresden, Germany ESUT Session, EAU Annual Meeting, Vienna, Austria Endourology Course, Taiba Hospital, Kuwait City, Kuwait EULIS Comprehensive Urolithiasis Workshop, Sofia, Bulgaria Annual Meeting Societé International d’Urologie, Berlin, Germany Istanbul Urolithiasis Days, Istanbul, Germany Masterclass Urolithiasis, Amsterdam, The Netherlands ESUT Session, EAU Annual Meeting, Paris, France 2nd Challenges in Endourology, Paris, France Workshop flexible URS, Beirut, Lebanon Endourology Meeting, Torino, Italy Prostate Surgery, Prosper Hospital, Germany Workshop Flexible URS, Amman, Jordan ESUT Winter-‐Meeting, Mannheim, Germany “Ureteroscopy” Live Surgery and Hands-‐on-‐Training, Surgical training course for residents, Mannheim, Germany “Mini-‐PNL” Live Surgery at the 2nd EULIS meeting, Copenhagen, Denmark Bipolar TUR-‐Prostate, TUR-‐Prostate Course of the German Working Group on Endourolgy, Heilbronn, Germany “Bipolar TUR-‐Prostate”, Endourology Meeting, Ahmedabad, India Edited Video “Ultra-‐Mini-‐PNL”, ESUT Live Surgery Session, EAU Annual Meeting, Stockholm, Sweden “Flexible Ureterorenoscopy”, Challenges in Endourology, Paris, France Rigid and flexible Ureterorenoscopy, Surgical training course for residents, Mannheim, Germany 20/06/14 11 Thomas Knoll, MD PhD MSc Bibliography Peer-‐Reviewed Original Publications 1. Rainer Birck, Thomas Knoll, Claude Braun, Michael Kirchengast, Klaus Münter, Fokko J. van der Woude, Peter Rohmeiss. Improvement of postischemic acute renal failure with the novel orally active endothelin-‐A receptor antagonist LU 135252 in rats. J Cardiovasc Pharmacol 1998; 32: 80-‐86 2. Rainer Birck, Stefan Krzossok, Thomas Knoll, Claude Braun, Fokko J. Van der Woude, Peter Rohmeis. Effect of the preferential cyclooxygenase-‐2 inhibitor meloxicam on renal perfusion compared to indomethacin. Exp Nephrology 2000; 8: 173-‐180 3. Maurice Stephan Michel, Kai Uwe Köhrmann, Thomas Knoll, Jeannette Hoang-‐ Böhm, Peter Alken. Clinical Evaluation of a newly developed endoscopic resection device (Rotoresect): Physical principle and first clinical results. Surgical Endoscopy 2001; 15:1395-‐1400 4. Francesco. J. Martinez Portillo, Damian. K. Osmonov, Thomas Knoll, Maurice Stephan Michel, Georg Blumberg, Peter Alken, Klaus-‐Peter Jünemann. Postoperativer Vergleich der Plikationsnähte Prolene vs. Gore-‐Tex auf die Lebensqualität von Patienten mit kongenitaler oder erworbener Penisdeviation. Aktuelle Urol 2001; 32: 96-‐100 5. Thomas Knoll, Sabine Schult, Rainer Birck, Claude Braun, Maurice Stephan Michel, Stephan Bross, Klaus-‐Peter Jünemann, Peter Rohmeiss, Michael Kirchengast. Therapeutic administration of an ET-‐A receptor antagonist after acute ischemic renal failure dose-‐dependently improves recovery of renal function. J Cardiovasc Pharmacol 2001; 37:483-‐488 6. Maurice Stephan Michel, Thomas Knoll, Taras Ptashnyk, Kai Uwe Köhrmann, Peter Alken. Flexible ureterorenoscopy for the treatment of lower pole calyx stones: influence of different lithotripsy probes and stone extraction tools on scope deflection and irrigation flow. Eur Urology 2002; 41:312-‐317 7. Thomas Knoll, Maurice Stephan Michel, Armando Cueva-‐Martínez, Stephan Bross, Martin Spahn, Peter Alken, Kai Uwe Köhrmann. Evaluation of superficial papillary laser ablation by endoscopic lasers on an ex-‐vivo kidney model. J Endourol 2002; 16:195-‐200 8. Maurice Stephan Michel, Thomas Knoll, Kai Uwe Köhrmann, Peter Alken. The URO Mentor: development and evaluation of a new computer-‐based interactive training system for virtual life-‐like simulation of diagnostic and therapeutic endourological procedures. Br J Urol 2002; 89:174-‐177 9. Thomas Knoll, Maurice Stephan Michel, Lutz Trojan, Peter Alken, Kai Uwe Köhrmann. Langzeitergebnisse der interstitiellen Laserkoagulation zur Behandlung der benignen Prostatahyperplasie. Aktuelle Urol 2003; 34: 48-‐51 10. Maurice Stephan Michel, Thomas Knoll, Lutz Trojan, Kai Uwe Köhrmann, Peter Alken. The Rotoresect-‐System for Bloodless Transurethral Ablation of the Prostate: Four-‐Year Follow-‐up. Br J Urol 2003; 91:65-‐68 11. Thomas Knoll, Jens Oltersdorf, Uwe Göttmann, Maurice Stephan Michel, Meike Schaub, Fokko J. van der Woude, Peter Rohmeiss, Claude Braun. Influence of acute selective endothelin-‐receptor-‐A blockade on renal hemodynamics in a rat model of chronic allograft rejection. Transpl Int 2003; 16:425-‐9 12. Thomas Knoll, Anton Musial, Lutz Trojan, Taras Ptashnyk, Peter Alken, Kai Uwe Köhrmann. Measurement of Renal Anatomy For Prediction of Lower Pole Caliceal 20/06/14 12 Thomas Knoll, MD PhD MSc Stone Clearance: Reproducibility of Different Parameters. J Endourol 2003, 17:447-‐451 13. Stephan Bross, Peter M. Braun, Joachim Weiß, Francisco J. Martinez Portillo, Thomas Knoll, Christoph Seif, Klaus-‐Peter Jünemann, Peter Alken. The role of the carbachol test and concommittant diseases in patients with nonobstructive urinary retention undergoing sacral neuromodulation. World J Urol 2003; 20: 346-‐649 14. Sreedhar Sagi, Thomas Knoll, Lutz Trojan, Axel Schaaf, Peter Alken, Maurice Stephan Michel. Gene delivery into prostate cancer cells by holmium laser application. Prostate Cancer Prostatic Dis 2003; 6:127-‐130 15. Stephan Bross, Peter Martin Braun, Francisco J. Martinez Portillo, Thomas Knoll, Christoph Seif, Klaus-‐Peter Jünemann. Sakrale Neuromodulation bei nichtobstruktiver, chronischer Harnretention: Die Wertigkeit des Carbacholtest und der Einfluss der assoziierten Nervenläsion. Aktuelle Urol 2003; 34:157 161 16. Stephan Bross, Peter Martin Braun, Maurice Stephan Michel, Thomas Knoll, Francisco J. Martinez Portillo, Klaus-‐Peter Jünemann, Peter Alken. Blasenwandspannung unter physiologischer Blasenentleerung und bei Patienten mit Detrusorhyperaktivität und subvesikaler Obstruktion. Aktuelle Urol 2003; 34:43-‐47 17. Tamara McNealy, Manfred Frey, Lutz Trojan, Thomas Knoll, Peter Alken, Maurice Stephan Michel. Intrinsic presence of poly (ADP-‐ribose) is significantly increased in malignant prostate compared to benign prostate cell lines. Anticancer Research, 2003, 23:1473-‐1478 18. Uwe Göttmann, Jens Oltersdorf, Meike Schaub, Thomas Knoll, Walter E. Back, Fokko J. van der Woude, Claude Braun. Oxidative stress in chronic renal allograft nephropathy in rats: effects of long-‐term treatment with carvedilol, BM 91.0228, or alpha-‐tocopherol J Cardiovasc Pharmacol. 2003; 42:442-‐50 19. Axel Häcker, Martin Hatzinger, Thomas Knoll, Maurice Stephan Michel, Kai Uwe Köhrmann, Peter Alken, Michael Siegsmund. Metachronous testicular tumor of an extragonadal germ cell tumor. Aktuelle Urol 2003; 34:413-‐415 20. Axel Schaaf, Sigrun Langbein, Thomas Knoll, Peter Alken, Maurice Stephan Michel. In vitro transfection of human bladder cancer cells by acoustic energy. Anticancer Res 2003; 6C:4871-‐4875 21. Thomas Knoll, Sreedhar Sagi, Lutz Trojan, Peter Alken, Maurice Stephan Michel. In vitro and ex vivo gene delivery into proximal tubular cells by means of laser energy – a potential approach for curing cystinuria? Urol Res 2004; 32:129-‐132 22. Lutz Trojan, Daniel Thomas, Thomas Knoll, Rainer Grobholz, Peter Alken, Maurice Stephan Michel. Expression of pro-‐angiogenic growth factors VEGF, EGF and bFGF and their topographical relation to neovascularisation in prostate cancer. Urol Res 2004; 32:97-‐103 23. Tamara L. McNealy, Lutz Trojan, Thomas Knoll, Peter Alken, Maurice S. Michel. Micelle delivery of Doxorubicin increases cytotoxicity to prostate carcinoma cells. Urol Res 2004; 32:255-‐260 24. Thomas Knoll, Lutz Trojan, Annette Steidler, Maurice Stephan Michel, Peter Alken. Influence of oxalate on tubular and epithelial renal cell lines. Urol Res 2004; 32:304-‐309 25. Thomas Knoll, Lutz Trojan, Sigrun Langbein, Sreedhar Sagi, Peter Alken, Maurice Stephan Michel. Impact of Holmium:YAG and Neodymium:YAG lasers on the efficacy of DNA delivery in transitional cell carcinoma. Lasers Med Sci 2004; 19:33-‐36 20/06/14 13 Thomas Knoll, MD PhD MSc 26. Stephan Bross, Sigmund Pomer, Leonard Doderlein, Thomas Knoll, Maurice Stephan Michel, Gerd Staehler, Hans-‐Jürgen Gerner, Peter Alken. Urodynamic findings in patients with infantile cerebral palsy. Aktuelle Urol 2004; 35:54-‐57 27. Maurice Stephan Michel, Philipp Erben, Lutz Trojan, Axel Schaaf, Koba Kiknavelidze, Thomas Knoll, Peter Alken. Acoustic energy: a new transfection method for cancer of the prostate, cancer of the bladder and benign kidney cells. Anticancer Res 2004; 24:2303-‐2308 28. Lutz Trojan, Daniel Thomas, Dorothee Friedrich, Rainer Grobholz, Thomas Knoll, Peter Alken, Maurice Stephan Michel. Expression of different vascular endothelial markers in prostate cancer and BPH tissue: an immunohistochemical and clinical evaluation. Anticancer Res 2004; 24:1651-‐1656 29. Maurice Stephan Michel, Philipp Erben, Lutz Trojan, Axel Schaaf, Koba Kiknavelidze, Thomas Knoll, Peter Alken. Acoustic energy: a new transfection method for cancer of the prostate, cancer of the bladder and benign kidney cells. Anticancer Res 2004; 24:2303-‐8 30. Axel Häcker, Kai Uwe Köhrmann, Thomas Knoll, Sigrun Langbein, Annette Steidler, Oliver Kraut, Ernst Marlinghaus, Peter Alken, Maurice Stephan Michel. High-‐ intensity focused ultrasound for ex vivo kidney tissue ablation: influence of generator power and pulse duration. J Endourol 2004; 18:917-‐924 31. Thomas Knoll, Lutz Trojan, Axel Häcker, Peter Alken, Maurice Stephan Michel. Validation of computer-‐based training in ureterorenoscopy. BJU Int 2005; 95:1276-‐9 32. Mahmoud Osman, Yvonne Alfano, Axel Häcker, Peter Alken, Maurice Stephan Michel, Thomas Knoll. 5-‐year follow-‐up of patients with clinically insignificant residual fragements after extracorporeal shockwave lithotripsy. Eur Urol 2005; 47:860-‐4 33. Mahmoud Osman, Gunnar Wendt-‐Nordahl, Katrin Heger, Peter Alken, Maurice Stephan Michel, Thomas Knoll. Percutaneous nephrolithotomy with ultrasonography-‐guided renal accesss: experience from over 300 cases. BJU Int 2005; 96:875-‐8 34. Thomas Knoll, Lutz Trojan, Axel Häcker, Peter Alken, Maurice Stephan Michel. Validation of computer-‐based training in ureterorenoscopy. BJU Int 2005; 95:1276-‐9 35. Stefan Kamp, Thomas Knoll, Mahmoud Osman, Axel Häcker, Maurice Stephan Michel, Peter Alken: Donor-‐site morbidity in buccal mucosa urethroplasty: lower lip or inner cheek? BJU Int 2005; 96:619-‐23 36. Axel Häcker, Stefan Vallo, Christel Weiss, Rainer Grobholz, Peter Alken, Thomas Knoll, Maurice Stephan Michel: Minimally invasive treatment of renal cell carcinoma: Comparison of 4 different monopolar radiofrequency devices. Eur Urol 2005; 48:584-‐92 37. Gunnar Wendt-‐Nordahl, Axel Häcker, K Fastenmeier, Thomas Knoll, Oliver Reich, Peter Alken, Maurice Stephan Michel: New Bipolar Resection Device for Transurethral Resection of the Prostate: First ex-‐Vivo and in-‐Vivo Evaluation. J Endourol 2005; 19:1203-‐9 38. Axel Häcker, Stefan Vallo, Christel Weiss, T Stein, Peter Alken, Thomas Knoll, Maurice Stephan Michel: Technical characterization of a new bipolar and multipolar radiofrequency device for minimally invasive treatment of renal tumours. BJU Int 2006; 97:822-‐8 20/06/14 14 Thomas Knoll, MD PhD MSc 39. Patrick Honeck, Axel Häcker, Peter Alken, Maurice Stephan Michel, Thomas Knoll: Shock wave lithotripsy versus ureteroscopy for distal ureteral calculi: a prospective study. Urol Res 2006; 34:190-‐2 40. Stefan Kamp, Thomas Knoll, Mahmoud Osman, Kai Uwe Köhrmann, Maurice Stephan Michel, Peter Alken: Low-‐power holmium: YAG laser urethrotomy for treatment of urethral strictures: functional outcome and quality of life. J Endourol 2006; 20:38-‐41 41. Axel Häcker, Stefan Vallo, Christel Weiss, Rainer Grobholz, T Stein, Thomas Knoll, Maurice Stephan Michel: Bipolar and multipolar radiofrequency ablation with resistance controlled power output: standardized ex vivo kidney tissue ablation: J Urol 2006; 175(3 Pt 1):1122-‐6 42. Thorsten J Wilhelm, Thomas Knoll, Gerald Weisser, Rainer Grobholz, Kai Uwe Köhrmann, Stefan Post: Urothelial carcinoma of the ureter, giant rectal stone and sigmoid carcinoma 55 years after ureterosigmoidostomy. Scanc J Urol Nephrol 2006; 40:172-‐3 43. Kilian Rödder, Roberto Olianas, Roland Dahlem, Thomas Knoll, Margit Fisch: Retroperitoneoscopy to extract an amorphous matrix calculus of the right kidney. Urologe A 2006; 45:626-‐8 44. Thorsten J Wilhelm, Thomas Knoll, Gerald. Weisser, Rainer Grobholz, Kai Uwe Köhrmann, Stephan Post: Urothelial carcinoma of the ureter, giant rectal stone and sigmoid carcinoma 55 years after ureterosigmoidostomy. Scand J Urol Nephrol 2006; 40: 172-‐3 45. Axel Häcker, Stefan Vallo, Christel Weiss, T Stein, Peter Alken, Thomas Knoll, Maurice Stephan Michel: Technical characterization of a new bipolar and multipolar radiofrequency device for minimally invasive treatment of renal tumours. BJU Int 2006 ; 97 : 822-‐8 46. Axel Häcker, Stefan Vallo, Christel Weiss, Rainer Grobholz, T. Stein, Thomas Knoll, Maurice Stephan Michel: Bipolar and multipolar radio frequency ablation with resistance controlled power output: standardized ex vivo kidney tissue evaluation. J Urol 2006 Mar; 175(3 Pt 1): 1122-‐6 47. Patrick Honeck, Axel Häcker, Peter Alken, Maurice Stephan Michel, Thomas Knoll: Shock wave lithotripsy versus ureteroscopy for distal ureteral calculi: a prospective study. Urol Res 2006; 34: 190-‐2 48. Stefan Kamp, Thomas Knoll, Mahmoud Osman, Kai Uwe Köhrmann, Maurice Stephan Michel, Peter Alken: Low-‐power holmium: YAG laser urethrotomy for treatment of urethral strictures: functional outcome and quality of life. J Endourol 2006; 20: 38-‐41 49. Yanwei Cao, Sreedhar Sagi, Axel Haecker, Annette Steidler, Peter Alken, Thomas Knoll: Impact of hypoxia and hypercapnia on calcium oxalate toxicity in renal epithelial and interstitial cells. Urol Res 2006; 34: 271-‐6 50. Patrick Honeck, Gunnar Wendt-‐Nordahl, Axel Häcker, Peter Alken, Thomas Knoll: Risk of Collateral Damage to Endourologic Toos by Holmium YAG Laser Energy. J Endourol 2006; 20: 495-‐7 51. Axel Hacker, K. Peters, Thomas Knoll, E. Marlinghaus, Peter Alken, J.W. Jenne, Maurice Stephan Michel: Ablation of clinically relevant kidney tissue volumes by high-‐intensity focused ultrasound: Preliminary results of standardized ex-‐vivo investigations. J Endourol 2006; 20:930-‐8. 52. Gunnar Wendt-‐Nordahl, Harald Rotert, Candida Peter, Peter Alken, Maurice Stephan Michel, Thomas Knoll. Intravenous contrast media in urology: evaluation of safety and tolerability in 49,975 patients. Med Princ Pract 2006; 15: 358-‐361 20/06/14 15 Thomas Knoll, MD PhD MSc 53. Thomas Knoll, Maurice Stephan Michel, Peter Alken: Surgical Atlas. Percutaneous nephrolithotomy: the Mannheim technique. BJU Int. 2007; 99:213-‐31 54. Axel Hacker, Gunnar Wendt-‐Nordahl, Patrick Honeck, Maurice Stephan Michel, Peter Alken, Thomas Knoll. A biological model to teach percutaneous nephrolithotomy technique with ultrasound-‐ and fluoroscopy-‐guided access. J Endourol 2007; 21:545-‐50 55. Gunnar Wendt-‐Nordahl, Lutz Trojan, Peter Alken, Maurice Stephan Michel, Thomas Knoll. Retrograde Ureterorenoscopy for stone treatment using a new 270° semiflexible scope – in vitro, ex vivo and clinical application. J Endourol 2007; 21:1439-‐1444 56. Gunnar Wendt-‐Nordahl, Patrick Krombach, Dieter Hannak, Axel Hacker, Maurice Stephan Michel, Peter Alken, Thomas Knoll. Prospective evaluation of acute endocrine pancreatic injury as collateral damage of shock wave lithotripsy for upper urinary tract stones. BJU Int 2007; 100:1339-‐43. 57. Gunnar Wendt-‐Nordahl, Birgit Bucher, Axel Hacker, Thomas Knoll, Peter Alken, Maurice Stephan Michel. Development of mortality and morbidity of TUR-‐ Prostate over 17 years in a single center. J Endourol 2007; 21:1081-‐1087 58. Gunnar-‐Wendt-‐Nordahl, Silke Hukele, Patrick Honeck, Peter Alken, Thomas Knoll, Maurice Stephan Michel, Axel Häcker. 980-‐nm Diode Laser: A Novel Laser Technology for Vaporization of the Prostate. Eur Urol. 2007; 52:1723-‐8. 59. Glenn M Preminger, Hans Göran Tiselius, Dean G Assimos, Peter Alken, A Colin Buck, Michele Gallucci, Thomas Knoll, Jim E Lingeman, Stephen Y Nakada, Magarete S Pearle, Kemal Sarica, Christian Türk, J Stuart Wolf Jr; American Urological Association Education and Research, Inc; European Association of Urology. 2007 Guideline for the management of ureteral calculi. Eur Urol. 2007; 52:1610-‐31. 60. Glenn M Preminger, Hans Göran Tiselius, Dean G Assimos, Peter Alken, A Colin Buck, Michele Gallucci, Thomas Knoll, Jim E Lingeman, Stephen Y Nakada, Magarete S Pearle, Kemal Sarica, Christian Türk, J Stuart Wolf Jr; EAU/AUA Nephrolithiasis Guideline Panel. 2007 guideline 16ort he management of ureteral calculi. J Urol. 2007;178:2418-‐34. 61. Gunnar Wendt-‐Nordahl, Sreedhar Sagi, Christian Bolenz, Peter Alken, Maurice S Michel, Thomas Knoll. Evaluation of cystine transport in cultured human kidney cells and establishment of cystinuria type I phenotype by antisense technology. Urol Res. 2008;36:25-‐29 62. Thomas Zimmerer, Axel Häcker, Hans P Hammes, Claude Braun, Peter Alken, Thomas Knoll. Hospital-‐based evaluation urolithiasis – A link between stone formation and urolithiasis? Urol Int 2009; 82: 350-‐355 63. Gunnar Wendt-‐Nordahl, Sabine Huckele, Patrick Honeck, Peter Alken, Thomas Knoll, Maurice Stephan Michel, Axel Häcker. Systematic Evaluation of a Recently Introduced 2-‐Micron Continuous Wave Thulium Laser for Vaporesection of the Prostate. J Endourol 2008; 22:1041-‐145 64. Thomas Knoll für den Arbeitskreis Harnsteine der Deutschen Gesellschaft für Urologie. S2 Leitlinie zur Diagnostik, Therapie und Metaphylaxe der Urolithiasis: Teil 1: Diagnostik und Therapie. Urologe A 2009; 48: 917-‐924 65. Thomas Knoll für den Arbeitskreis Harnsteine der Deutschen Gesellschaft für Urologie. S2 Leitlinie zur Diagnostik, Therapie und Metaphylaxe der Urolithiasis: Teil 2: Metabolische Diagnostik und Metaphylaxe. Urologe A 2009; 48: 1084-‐1093 66. Elmar Heinrich, Gunnar Wendt-‐Nordahl, Patrick Honeck, Peter Alken, Thomas Knoll, Maurice Stephan Michel, Axel Häcker. 120 W lithium triborate vaporization of the prostate: comparison with 80 W potassium-‐titanyl-‐phosphate laser in an 20/06/14 16 Thomas Knoll, MD PhD MSc ex-‐vivo model. J Endourol 2010; 24: 75-‐79 67. Thomas Knoll, Felix Wezel, Maurice Stephan Michel, Patrick Honeck, Gunnar Wendt-‐Nordahl. Do patients benefit from miniaturized tubeless percutaneous nephrolithotomy? A comparative prospective study. J Endourol 2010; 24: 1075-‐ 179 68. Thomas Knoll, Anne B Schubert, Dirk Fahlenkamp, Dietbert B Leusmann, Gunnar Wendt-‐Nordahl, Gernot Schubert. Urolithiasis through the ages: data on more than 200,000 urinary stone analyses. J Urol 2011; 185: 1304-‐1311 69. Gunnar Wendt-‐Nordahl, Tuna Mut, Patrick Krombach, Maurice Stephan Michel, Thomas Knoll. Do new generation flexible ureterorenoscopes offer a higher treatment success than their predecessors? Urol Res 2011; 39: 185-‐188 70. Markus Ritter, Patrick Krombach, Thomas Knoll, Maurice Stephan Michel, Axel Häcker. Initial experience with a newly developed antirefluxive ureter stent. Urol Res 2012; 40: 349-‐353 71. Thomas Knoll, Jan P. Jessen, Patrick Honeck, Gunnar Wendt-‐Nordahl. Flexible ureterorenoscopy versus miniaturized PNL for solitary renal calculi of 10-‐30 mm size. World J Urol 2011; 29:755-‐759 72. Patrick Honeck, Gunnar Wendt-‐Nordahl, Jens Rassweiler, Thomas Knoll. Three-‐ dimensional laparoscopic imaging improves surgical performance on standardized ex-‐vivo laparoscopic tasks. J Endourol 2012; 26:1085-‐1088 73. Francesco Sanguedolce, Alberto Breda, Felix Milan, Marianne Brehmer, Thomas Knoll, Evangelos Liatsikos, Palle Osther, Olivier Traxer, Cesare Scoffone, . Lower pole stones: prone PCNL versus supine PCNL in the International Cooperation in Endourology (ICE) group experience. World J Urol 2013; 31: 1575-‐1582 74. Cosentino M, Breda A, Sanguedolce F, Landman J, Stolzenburg JU, Verze P, Rassweiler J, Van Poppel H, Klingler HC, Janetschek G, Celia A, Kim FJ, Thalmann G, Nagele U, Mogorovich A, Bolenz C, Knoll T, Porpiglia F, Alvarez-‐Maestro M, Francesca F, Deho F, Eggener S, Abbou C, Meng MV, Aron M, Laguna P, Mladenov D, D'Addessi A, Bove P, Schiavina R, De Cobelli O, Merseburger AS, Dalpiaz O, D'Ancona FC, Polascik TJ, Muschter R, Leppert TJ, Villavicencio H. The use of mannitol in partial and live donor nephrectomy: an international survey. World J Urol. 2013; 31: 977-‐982 75. Jan Peter Jessen, Jan P. Jessen, Patrick Honeck, Thomas Knoll, Gunnar Wendt-‐ Nordahl. Percutaneous nephrolithotomy under combined sonographic/radiologic guided puncture: results of a learning curve using the modified Clavien system. World J Urol 2013; 31: 1599-‐1603 76. Liatsikos E, Knoll T, Kyriazis I, Georgiopoulos I, Kallidonis P, Honeck P, Stolzenburg JU. Unfavorable outcomes of laparoscopic pyeloplasty using barbed sutures: a multi-‐center experience. World J Urol. 2013; 31: 1441-‐1444 77. Doizi S, Knoll T, Scoffone CM, Breda A, Brehmer M, Liatsikos E, Cornu JN, Traxer O. First clinical evaluation of a new innovative ureteral access sheath (Re-‐Trace): An European Study. World J Urol 2014; 32: 143-‐147 78. Wendt-‐Nordahl G, Meister L, Sagi S, Honeck P, Michel MS, Knoll T. Evaluation of alkalinization and chelating agent therapy in murine cystinuria model. J Urol 2014 (submitted) 79. Sanguedolce F, Liatsikos E, Verze P, Hruby S, Breda A, Binbay M, Knoll T. Use of flexible ureteroscopy in the clinical practice for the treatment of renal stones: 20/06/14 17 Thomas Knoll, MD PhD MSc Results from a large European survey conducted by the EAU Young Academic Urologists Working Group. Urolithiasis 2014 (ePub) 80. Khan SA, Chang RT, Ahmed K, Knoll T, van Velthoven R, Challacombe B, Dasgupta P, Rane A. Live Surgical education: A perspective from the surgeons who perform it. BJU Int 2013 (ePub) 81. Jessen JP, Honeck P, Knoll T, Wendt-‐Nordahl G. Flexible ureterorenoscopy for lower pole stones: influence of the collecting system’s anatomy. J Endourol 2014; 28: 146-‐151 82. Schoenthaler M, Buchholz, N, Farin E, Ather H, Bach C, Bach T, Denstedt JD, Fritsche HM, Grasso M, Hakenberg OW, Herwig R, Knoll T, Kuehhas FE, Liatsikos E, Liske P, Marberger M, Osther PJ, Santos JM, Sarica K, Seitz C, Straub, Traxer O, Trincheri A, Turney B, Miernik A. The post-‐ureteroscopic lesion scale (PULS): a multicenter video-‐based evaluation oft he inter-‐rater reliablity. World J Urol 2013 (ePub) 83. Artibani W, Ficarra V, Challacombe BJ, Abbou CC, Bedke J, Boscolo-‐Berto R, Brausi M, de la Rosette JJ, Deger S, Denis L, Guazzoni G, Guillonneau B, Heesakkers JP, Jacmin D, Knoll T, Martínez-‐Pineiro L, Montorsi F, Mottrie A, Piechaud PT, Rane A, Rassweiler J, Stenzl A, van Moorselaar J, van Velthoven RF, van Poppel H, Wirth M, Abrahamsson PA, Parsons KF. EAU Policy on Live Surgery Events. European Urology 2014; 66: 87-‐97) 84. Francesco Sanguedolce, Evangelos Liatsikos, P Verve, Stefan Hruby, Alberto Breda, JD Beatty, Thomas Knoll. Use of flexible ureterorenoscopy in the clinical practice for the treatment of renal stones. Results from a large European survey conducted by the EAU Young Academic Urologists Working party on Endourology and Urolithiasis. Urolithiasis 2014 (in press) 85. Reviews and Editorials 1. Thomas Knoll, Meike Schaub, Rainer Birck, Claude Braun, Klaus-‐Peter Jünemann, Peter Rohmeiss. The renoprotective potential of endothelin receptor antagonists. Expert Opinions On Investigational Drugs 2000; 9: 1041-‐1052 2. Maurice Stephan Michel, Thomas Knoll, Kai Uwe Köhrmann, Peter Alken. Endourology: Virtual-‐reality Training. Deutsches Ärzteblatt 2002; Ausgabe B: 2012-‐2013 3. Wilhelm Hochreiter, Thomas Knoll, Bernhard Hess. Pathophysiology, Diagnostics and conservative Therapy of non-‐calcium stones. Therapeut Umschau 2003; 60: 89-‐97 4. Thomas Knoll, Maurice Stephan Michel, Kai Uwe Köhrmann, Peter Alken. Interventional Therapy of Urinary Stones (I) – ESWL. Therapeut Umschau 2003; 60: 98-‐102 5. Thomas Knoll, Maurice Stephan Michel, Kai Uwe Köhrmann, Peter Alken. Interventional Therapy of Urinary (II) – Endoscopic Techniques. Therapeut Umschau 2003; 60: 103-‐107 6. Thomas Knoll, Maurice Stephan Michel, Peter Alken. 55. DGU Annual Meeting: Scientific background and abstract selection. Urologe A, 2003 20/06/14 18 Thomas Knoll, MD PhD MSc 7. Thomas Knoll, Volker Janitzky, Maurice Stephan Michel, Peter Alken, Kai Uwe Köhrmann. Cystinuria – Current recommendations on Diagnostics, Therapy and Follow-‐up. Aktuelle Urol 2003; 34: 97-‐101 8. Thomas Knoll, Lutz Trojan, Axel Häcker, Maurice Stephan Michel, Kai Uwe Köhrmann, Peter Alken. Minimal-‐invasive Therapy of Urolithiasis. Aktuelle Urol 2003; 34: 313-‐318 9. Thomas Knoll, Maurice Stephan Michel, Peter Alken. Interventional Treatment of Urinary Stones. Dtsch Med Wochenschr 2003; 128: 1485-‐1488 10. Maurice Stephan Michel, Lutz Trojan, Thomas Knoll, Stephan Bross, Peter Alken. Established and new urological therapeutic options in the management of prostate carcinoma. Radiologe 2003; 43: 441-‐447 11. Thomas Knoll. What is your diagnosis? Incomplete renal tubular acidosis type I. Schweiz Rundsch Med Prax 2004; 93:183-‐184 12. Thomas Knoll. Emergency cases in Urology. Notfallmedizin 2004; 29: 487 13. Thomas Knoll, Lutz Trojan, Axel Häcker, Maurice Stephan Michel, Kai Uwe Köhrmann, Peter Alken. Therapy of Urinary Stones: Treatment and Follow-‐up. Notfallmedizin 2004; 29: 506-‐513 14. Thomas Knoll, Antonia Zöllner, Gunnar Wendt-‐Nordahl, Peter Alken, Maurice Stephan Michel: Cystinuria in childhood and adolescence: Recommendations for diagnosis, treatment and follow-‐up. Pediatr Nephrol 2005; 20: 19-‐24 15. Lutz Trojan, Axel Schaaf, Annette Steidler, Markus Haak, Georg Thalmann, Thomas Knoll, Norbert Gretz, Peter Alken, Maurice Stephan Michel. Identification of metastasis-‐associated genes in prostate cancer by genetic profiling of human prostate cancer cell lines. Anticancer Res 2005;25(1A):183-‐91 16. Lutz Trojan, Koba Kiknavelidze, Thomas Knoll, Peter Alken, Maurice Stephan Michel. Prostate cancer therapy: standard management, new options and experimental approaches. Anticancer Research 2005; 25: 551-‐61 17. Thomas Knoll, Gunnar Wendt-‐Nordahl, Peter Alken. PNL: Indications, Techniques and Results. Urologe A 2005; 44: 299-‐306 18. Thomas Knoll, Gunnar Wendt-‐Nordahl, Lutz Trojan, Andreas Wenke, Norbert Roeder, Peter Alken. Actual aspects of Stone Therapy. Akt Urol 2005; 36: 47-‐54 19. Thomas Knoll, Peter Alken, Maurice Stephan Michel. Progress in treatment of ureteric stones. Eur Urol 2005; EAU-‐EBU Update Series Urolithiasis 20. Thomas Knoll, Peter Alken. URS in the past, today and tomorrow. Urologe A 2006; 45 Suppl. 4: 185-‐186 21. Gunnar Wendt-‐Nordahl, Peter Alken, Thomas Knoll: Urolithiasis: Metabolics and Prevention. Arzneimitteltherapie 2006; 24: 6-‐12 22. Christian Türk, Thomas Knoll, Kai Uwe Köhrmann. New Guidelines on Urolithiasis: Progress or Problems? Urologe A 2008; 47: 591-‐593 23. Gunnar Wendt-‐Nordahl, Andy Evan, Martin Spahn, Thomas Knoll. New aspects of calcium oxalate stone formation. Urologe A 2008; 47: 540-‐544 24. Udo Nagele, Thomas Knoll, David Schilling, Maurice Stephan Michel, Arnulf Stenzl. Lower Pole Stones. Urologe A 2008; 47:875-‐884 25. Thomas Knoll. Editorial Comment: Training in percutaneous nephrolithotomy – a critical review. Eur Urol 2008; 54:1003 26. Gunnar Wendt-‐Nordahl, Yanwei Cao, Axel Häcker, Maurice Stephan Michel, Thomas Knoll. Transurethral resection of the prostate: defending its leading position in the management of benign prostatic enlargement. Minerva Urol Nefrol 2009; 61: 291-‐300 27. Thomas Knoll, Andre Tasca, Noor Buchholz. Treatment of small lower pole calculi 20/06/14 19 Thomas Knoll, MD PhD MSc – SWL vs. URS vs. PNL. Arch Ital Urol Androl 2011; 83: 6-‐9 28. Jens Rassweiler, Thomas Knoll, Kai Uwe Köhrmann, Jim A McAteer, Jim E Lingeman, Robin O Cleveland, Michael R Bailey, Christian Chaussy. Shock wave technology and application: an update. Eur Urol 2011; 59: 784-‐796 29. Thomas Knoll, Rainer Hofmann, Klaus Höfner. Benign hyperplasia and urolithiasis. Urologe A 2011; 50 Suppl. 1: 197-‐200 30. Thomas Knoll, Hans-‐Martin Fritsche, Jens Rassweiler. Current medical and economic aspects of stone treatment. Akt Urol 2011; 42:363-‐7 31. Thomas Knoll, Peter Alken. Beyond ESWL: New concepts for definitive stone treatment. World J Urol 2011; 29:703-‐706 32. Thorsten Bach, Rolf Muschter, Ramos Sroka, Stavros Gravas, Andreas Skolarikos, Thomas R. Herrmann, Thomas Bayer, Thomas Knoll, Claude C. Abbou, Günther Janetschek, Alexander Bachmann, Jens Rassweiler. Laser Treatment of benign prostatic obstruction: basics and physical differences. Eur Urol 2012; 61:317-‐25 33. Thomas Knoll. Simultaneous antegrade-‐retrograde Stone Treatment. Urologe 2013; 52: 686-‐690 34. Thomas Knoll, Ulrich Humke. Urolithiasis in childhood. Urologe 2013; 52: 1084-‐ 1091 35. Knoll T. Editorial comment: Mini PNL, Zeng et al. J Endourology 2014; 28: 267-‐ 268 36. Thomas Knoll, Gunnar Wendt-‐Nordahl. Ureterorenoscopy: Management of Complications. Urologe 2014; 53: 689-‐694 Non-‐Peer-‐Reviewed Publications 1. Maurice Stephan Michel, Thomas Knoll, Kai Uwe Köhrmann, Peter Alken. Endourologie: Multimediales interaktives Training. Deutsches Ärzteblatt 2002; Ausgabe B: 2012-‐2013 2. Wilhelm Hochreiter, Thomas Knoll, Bernhard Hess. Pathophysiologie, Diagnostik und konservative Therapie nicht-‐kalziumhaltiger Harnsteine. Therapeut Umschau 2003; 60: 89-‐97 3. Thomas Knoll, Maurice Stephan Michel, Kai Uwe Köhrmann, Peter Alken. Interventionelle Therapie des Harnsteinleidens (I) – Extrakorporale Stoßwellenlithotripsie. Therapeut Umschau 2003; 60: 98-‐102 4. Thomas Knoll, Maurice Stephan Michel, Kai Uwe Köhrmann, Peter Alken. Interventionelle Therapie des Harnsteinleidens (II) – Endoskopische Verfahren. Therapeut Umschau 2003; 60: 103-‐107 5. Thomas Knoll. What is your diagnosis? Incomplete renal tubular acidosis type I. Schweiz Rundsch Med Prax 2004; 93:183-‐184 6. Thomas Knoll, Maurice Stephan Michel, Peter Alken. 55. Kongress der Deutschen Gesellschaft für Urologie – Auswahl-‐ und Begutachtungsverfahren für wissenschaftliche Beiträge. Urologe A, 2003 7. Thomas Knoll. Urologische Notfälle. Notfallmedizin 2004; 29: 487 8. Thomas Knoll, Lutz Trojan, Axel Häcker, Maurice Stephan Michel, Kai Uwe Köhrmann, Peter Alken. Interventionelle Therapie von Harnsteinen: Indikationen, Ergebnisse und Komplikationen. Notfallmedizin 2004; 29: 506-‐513 9. Gunnar Wendt-‐Nordahl, Peter Alken, Thomas Knoll. Harnsteinleiden. Medikamentöse Therapie und Metaphylaxe. Arzneimitteltherapie 2006; 24: 6-‐12 20/06/14 20 Thomas Knoll, MD PhD MSc 10. Heiko Kohns, Thomas Knoll. Therapie von Nierentumoren. Klinische Onkologie 2011; 5 Books Book As Editor „Clinical Urolithiasis“, T. Knoll/M. Pearle, Springer, Heidelberg 2012 „Urolithiasis“, Subsection Editor, in „Die Urologie“, Springer, Heidelberg, 2013 Book Chapters 1. Chapter “Urolithiasis” in “Lehrbuch Urologie”, Eds. U. Schmelz, C. Sparwasser, W. Weidner, Springer Verlag Heidelberg (2005) 2. Chapter “Urolithiasis – To screen or not to screen” in “Evidence for Urology”, Eds. Muir, C. Dawson, tfm publishing, London, UK (2005) 3. Chapter “Ureterorenoscopy” in “Manual Endourology”, Ed. R. Hohenfellner, Springer Verlag Heidelberg (2005) 4. Chapter „Endourological Techniques – Clinical Pathways” in „Therapeutic Energy Applications in Urology“, Eds.. C. Chaussy, G. Haupt, D. Jocham, K.U. Köhrmann, D. Wilbert, Thieme Verlag Stuttgart, (2005) 5. Chapter „Cystinuria“ in „Enzyclopaedia of Molecular Mechanisms of Diseases“, Springer Verlag Heidelberg (2009) 6. Chapter „Percutaneous nephrolithotomy“ in „Top Tips in Endourology“, Eds. A. Rané, M. Monga, Mihir Desai, F. Keeley, Euromed Publishers, 2008 7. Chapter „Medical and Surgical treatment of cystinuria“in „Top Tips in Endourology“, Eds. A. Rané, M. Monga, Mihir Desai, F. Keeley, Euromed Publishers, 2008 8. Chapter „Interventional stone treatment“ in „Therapeutic Energy Applications in Urology“, Eds.. C. Chaussy, G. Haupt, D. Jocham, K. U. Köhrmann, Thieme Verlag Stuttgart (2010) 9. Chapter „Open Stone Surgery“ in „Textbook of Urinary Stone Disease“, Eds. N. Rao, G. Preminger, J. Kavanagh, Springer Verlag Heidelberg (2011) 10. Kapitel „Cystinuria and Cystine Stones“ in „Textbook of Urinary Stone Disease“, Eds. N. Rao, G. Preminger, J. Kavanagh, Springer Verlag Heidelberg (2011) 11. Chapter„Harnleiterschienung“ in „Komplikationen in der Urologie“, Ed. S. Steffens, Thieme Verlag Stuttgart (2012) 12. Chapter„Cystinuria“ in „Urolithiasis“, Tiselius, India Press (to be published 2013) 13. Chapter „Indications for interventional treatment“ in „Clinical Urolithiasis“, Eds. T. Knoll/M. Pearle, Springer Verlag Heidelberg (2012) 14. Chapter „Percutaneous nephrolithotomy in prone position“ in „Supine percutaneous nephrolithotomy“, Scoffone/Hoznek, Springer Verlag Heidelberg (2013) 15. Chapter „Percutaneous nephrolithotomy“ in „Urolithiasis, Basic Science and Clinical Practice“, Eds. J. Talati, H. G. Tiselius, D. Albala, G. Ye, Springer (2013) 16. Chapter „Urolithiasis“ in „Urology Exam“, Eds. H. Schmelz, F. Leyh, Thieme Verlag, Stuttgart (to be published 2014) 17. Chapter „Enuresis“ in „Urology at a glance“, Eds. Merseburger, Kuczyk, Moul, Springer (to be published in 2014) 20/06/14 21 Thomas Knoll, MD PhD MSc 18. Chapter „Urolithiasis“ in „Die Urologie“, Eds. Michel, Wirth, Sulser, Janetscheck, Springer (to be published in 2014) 19. Chapter „Urolithiasis“ in „Urologie Essentials“, Eds. Hegele, Skobek, Thieme (to be published in 2014) 20/06/14 22
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