Generic Name: rocuronium bromide 21-Sep-14 Trade Name: Zemuron Classification: non-depolarizing neuromuscular blocking agent Supplied: 10 mg/5 ml Actions (Pharmacodynamics): Skeletal muscle relaxant: Prevents neuromuscular transmission by blocking the effect of ACh at the myoneural junction, thus blocking depolarization. Indications: Medication facilitated intubation after administration of sedation/analgesia (when succinylcholine is contraindicated and sedation/analgesia is not enough to facilitate intubation and rescue airway available. Post intubation to facilitate airway control and maintain muscle relaxation. Adult/Paediatric Dosage: (3 months and older) MFI/Loading dose: 0.6 – 1.2 mg/kg IVP (in most patients intubation can proceed within 2 minutes) Maintenance dose: 0.2 – 0.6 mg/kg IVP Defasiculation dose: 0.06 mg/kg IVP Contraindications: Hypersensitivity to drug or components A difficult intubation in a patient who is presently self-ventilating adequately and ventilation may be difficult once paralyzed Precautions: Has no sedative/analgesic properties Notes: Acetylcholinesterase inhibitors, such as neostigmine, antagonize the action of rocuronium. Card 1 of 2 Generic Name: rocuronium bromide Route Onset 1 – 2 minutes IV 21-Sep-14 Peak Unknown Duration 30 – 60 minutes References: Portage College. (2012, June 25). Rocuronium Bromide. In C13 EMTP 212 Advanced Pharmacology. Retrieved September 21, 2014 Card 2 of 2
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