Introducing KXL II™ and Photorefractive Intrastromal Cross-linking (PiXL™) the next revolution in refractive correction The KXL® and KXL™ II Systems for performing Lasik Xtra® and Accelerated Cross-linking are not for sale in the United States. VibeX RapidTM, VibeX XtraTM, and ParaCelTM are not for sale in the United States. MA-00266 Rev A KXL II PiXL The Future of Cross-linking expanding the possibilities for your practice Avedro’s KXL II System allows patterned, precise, topography-guided accelerated cross-linking with: • Programmable and customizable illumination patterns • Seamless integration with leading industry topographers • Real-time eye tracking • Significantly higher power output Procedures performed with the KXL II System include PiXL, Lasik Xtra® and Accelerated Cross-linking. These procedures have the potential to: • Enhance cataract surgery without surgical intervention • Provide non-surgical refractive correction • Restore biomechanical integrity • Treat pathology with methods unavailable in other devices KXL II is CE Marked and not available for sale in the US. Visit avedro.com/kxl to learn more. Myopic Treatment Pre-Treatment Post-Treatment Difference Images courtesy of A. John Kanellopoulos, MD PiXL is only available with Avedro’s KXL II System. What the Experts are Saying: “ “As one of the first KXL II clinical sites, we experienced the amazing capabilities of customized accelerated cross-linking to achieve specific, reproducible and interim-stable refractive changes on the cornea. It seems to me that every surgeon who has performed cross-linking has experienced refractive corneal changes. We now have a way to design and customize these refractive changes. If these initial clinical results continue to be repeated, as I believe they will, the potential seems unlimited.” — A. John Kanellopoulos, MD ” “Through my involvement in the early stages of scientific development, I have experienced firsthand the potential that the KXL II has to truly change ophthalmology and to open up refractive correction to millions of patients. — John Marshall, MBE, PhD Avedro is a privately held medical device and pharmaceutical company advancing the science and technology of corneal cross-linking and refractive correction. Avedro’s products include capital equipment and related single dose pharmaceuticals. Those products are currently used to enhance Lasik outcomes in a procedure known as Lasik Xtra. Over 75,000 surgeries have been successfully performed outside the US using Avedro’s KXL System. The KXL System’s accelerated cross-linking, in combination with its pharmaceuticals, is also used to treat several important and debilitating ophthalmic pathologies. Avedro’s KXL and pharmaceutical products are currently being used in three Phase III US clinical trials involving over 100 clinical sites. Avedro distributes its products in 62 countries through 33 ophthalmic distributors with 115 representatives. Avedro products are not for sale in the US. 781.768.3400 | [email protected] | www.avedro.com The KXL® and KXL™ II Systems for performing Lasik Xtra® and Accelerated Cross-linking are not for sale in the United States. VibeX RapidTM, VibeX XtraTM, and ParaCelTM are not for sale in the United States. MA-00266 Rev A
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