PRE-PRINTED PHYSICIAN’S ORDERS USE BALL POINT PEN ONLY AN APPROVED THERAPEUTIC/GENERIC EQUIVALENT MAY BE DISPENSED PER PHARMACY & THERAPEUTICS COMMITTEE GUIDELINES. PREPRINTED ORDERS FOR: INPATIENT/OUTPATIENT RITUXIMAB TREATMENT Date Written: Appointment Day: Time: Other _________________________ CD-20 positive non-Hodgkins lymphoma OR: Diagnosis: (Page 1 of 1) Significant Comorbidities: ___________________________________________________ Height:_________cm Weight:__________kg NOTE: Orders with option indicator ( ) are to be carried out only if checked () 1. Lab Work: 2. PREMEDICATION: (before Rituximab infusion) 3. BSA________m2 a) Diphenhydramine (Benadryl) 25 mg IV x 1 dose b) Acetaminophen (Tylenol) 650 mg by mouth x 1 dose c) IV Normal Saline KVO CHEMOTHERAPY: A) Rituximab ____________ mg IV at 50 mg/hr (100mg/hour for subsequent infusions IF initial dose was tolerated as per policy) x 30 minutes, then if no hypersensitivity or infusion related events occur, escalate infusion rate per Rituximab Infusion Policy. B) Vital Signs every 15 min x 4, then if stable every 30 min. C) Adverse reactions: 1) Stop Rituximab infusion. 2) Call Physician. 3) Normal Saline IV @ 150 ml/hr prn Systolic Blood Pressure less than 90. 4) Blount Albuterol (Proventil) every 2 hours prn wheezing. 5) Methylprednisolone (SoluMedrol) 100 mg IV prn upper airway swelling. 6) Aqueous Epinephrine 1:1000 solution 0.3 ml subcutaneous prn anaphylaxis. 7) May resume Rituximab infusion at 50% rate after reaction clears, per physician order. 8) O2 at 2 Liters Per Minute PRN May give Rituximab by rapid infusion with subsequent doses per hospital rituximab policy D) Rapid infusion: total volume 250ml normal saline. Give 20% (50ml) over 30 minutes (100 ml/hour) then remaining 80% (200ml) over 1 hour (200ml/hour). Physician Signature: Date/Time: Revised: 06/2010 Place Patient Label Inside This Box Physicians Orders Inpatient/Outpatient Rituximab Treatment Page 1 of 1 7070.03.15003.01
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